Exhibit 99.1

The First Bancshares, Inc. Announces Earnings Guidance

    HATTIESBURG, Miss.--(BUSINESS WIRE)--May 31, 2006--The First
Bancshares, Inc. (NASDAQ:FBMS) today announces guidance on the
earnings for the quarter ending June 30, 2006. The First Bancshares,
Inc. earnings for the quarter ending June 30, 2006 will include $0.09
earnings per share gain on a parcel of real estate that was recently
sold.
    The First Bancshares, Inc. - the parent company of The First, A
National Banking Association - has assets of $311 million. Founded in
1996, The First operates 8 offices with locations in Hattiesburg,
Laurel, Purvis, Picayune, Pascagoula and Bay St. Louis, Mississippi.
    Investors can access additional information or on-line banking and
bill pay services at www.thefirstbank.com.

    CONTACT: The First Bancshares, Inc.
             David Johnson or Dee Dee Lowery, 601-268-8998