UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                               ------------------

                                    FORM 8-K

                                 CURRENT REPORT
     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

       Date of report (Date of earliest event reported): September 1, 2006

                              --------------------


                            Opexa Therapeutics, Inc.
                            ------------------------
             (Exact Name of Registrant as Specified in Its Charter)

                        (Formerly PharmaFrontiers Corp.)

                                      Texas
                                      -----
                 (State or Other Jurisdiction of Incorporation)

        000-25513                                        76-0333165
        ---------                                        ----------
(Commission File Number)                    (I.R.S. Employer Identification No.)

      2635 N. Crescent Ridge Drive
          The Woodlands, Texas                             77381
          --------------------                             -----
(Address of Principal Executive Offices)                 (Zip Code)

       Registrant's telephone number, including area code: (281) 272-9331

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

[ ]  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR  230.425)
[ ]  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)
[ ]  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange  Act (17 CFR  240.14d-2(b))
[ ]  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))



Item 8.01. Other Events.

On September 1, 2006, Registrant announced that its common shares will be listed
and begin trading on the NASDAQ Global  Market.  The Company's  trading  symbol,
OPXA, will remain  unchanged.  Opexa's common shares will no longer be listed on
the OTC Bulletin Board. A copy of the press release is attached as Exhibit 99.1.


Item 9.01 Financial Statements and Exhibits

(c) Exhibit 99.1

The following exhibit is to be filed as part of this 8-K:

Exhibit No.      Description
- -----------      -----------

99.1             Press release issued September 1, 2006



                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.



                                OPEXA THERAPEUTICS, INC.

                                By: /s/ David B. McWilliams
                                    --------------------------------------------
                                    David B. McWilliams, Chief Executive Officer

DATE: September 1, 2006







                                  EXHIBIT INDEX

Exhibit No.      Description
- -----------      -----------

99.1             Press release issued September 1, 2006