UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549



                                    FORM 8-K
                                 Current Report


                       Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934


                Date of Report (date of earliest event reported):

                                October 19, 2006



                     MEDICAL STAFFING NETWORK HOLDINGS, INC.
             (Exact name of registrant as specified in its charter)



           Delaware                  001-31299                65-0865171
       ----------------          ------------------      --------------------
  (State or other jurisdiction      (Commission             (IRS Employer
       of incorporation)            File Number)          Identification No.)


                901 Yamato Road, Suite 110, Boca Raton, FL 33431
                ------------------------------------------------
                    (Address of principal executive offices)

        Registrant's telephone number, including area code: 561-322-1300
                                                            ------------

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

     |_| Written communications pursuant to Rule 425 under the Securities Act
(17 CFR 230.425)

     |_| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17
CFR 240.14a-12)

     |_| Pre-commencement communications pursuant to Rule 14d-2(b) under the
Exchange Act (17 CFR 240.14d-2(b))

     |_| Pre-commencement communications pursuant to Rule 13e-4(c) under the
Exchange Act (17 CFR 240.13e-4(c))





Item 7.01. Regulation FD Disclosure

     The registrant is attaching a copy of a press release dated October 19,
2006, as Exhibit 99.1.


Item 9.01. Financial Statements and Exhibits

           (d) Exhibits:

               99.1  Press Release of Medical Staffing Network Holdings, Inc.,
                     dated October 19, 2006.


Limitation on Incorporation by Reference

     In accordance with General Instruction B.2 of Form 8-K, the information in
this report (including the exhibit) is furnished pursuant to Item 7.01 and shall
not be deemed to be "filed" for the purposes of Section 18 of the Securities
Exchange Act of 1934, as amended, or otherwise subject to liabilities of that
Section, unless we specifically incorporate it by reference in a document filed
under the Securities Act of 1933 or the Securities Exchange Act of 1934. The
filing of this Current Report on Form 8-K is not an admission as to the
materiality of any information in this report that is required to be disclosed
solely by Regulation FD.






                                    SIGNATURE

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.



Date: October 19, 2006                       MEDICAL STAFFING NETWORK
                                             HOLDINGS, INC.



                                             By: /s/ Kevin S. Little
                                                 ------------------------
                                                 Kevin S. Little
                                                 President and Chief Financial
                                                 Officer






                                  EXHIBIT INDEX



Exhibit No.    Description

99.1           Press Release of Medical Staffing Network Holdings, Inc., dated
               October 19, 2006.