Exhibit 32.2

                    CERTIFICATION OF CHIEF FINANCIAL OFFICER
            IN ACCORDANCE WITH SECTION 906 OF THE SARBANES-OXLEY ACT

         In connection with the quarterly report of Sharps Compliance Corp. (the
"Company") on Form 10-QSB for the three months ended September 30, 2006, as
filed with the Securities and Exchange Commission on the date hereof, I, David
P. Tusa, Executive Vice President, Chief Financial Officer, Business Development
and Corporate Secretary of the Company, certify, pursuant to 18 U.S.C. ss.1350,
as adopted pursuant to ss.906 of the Sarbanes-Oxley Act of 2002, to the best of
my knowledge that:

     (1)  The Form 10-QSB report for the three months ended  September 30, 2006,
          filed with the Securities and Exchange Commission on November 9, 2006,
          fully complies with the  requirements of Section 13(a) or 15(d) of the
          Securities Exchange Act of 1934; and

     (2)  The  information  contained  in the Form  10-QSB  report for the three
          months  ended  September  30, 2006 fairly  presents,  in all  material
          respects,  the financial condition and results of operations of Sharps
          Compliance Corp.


By:  /s/ DAVID P. TUSA                                    Date: November 9, 2006
   ---------------------
David P. Tusa
Executive Vice President
Chief Financial Officer,
Business Development and
Corporate Secretary


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