EXHIBIT 99.1

    Medical Staffing Network Announces Acquisition of AMR ProNurse

    BOCA RATON, Fla.--(BUSINESS WIRE)--Sept. 13, 2007--Medical
Staffing Network Holdings, Inc. (NYSE: MRN), the third largest
healthcare staffing company and the largest provider of per diem nurse
staffing services in the nation as measured by revenues, announced
today that it has completed the asset acquisition of AMR ProNurse for
$11.0 million in cash. AMR ProNurse provides nurses, allied healthcare
and other medical professionals to healthcare facilities in the
greater Chicago area and is a market leader in healthcare Vendor
Management Services (VMS) with their OneSource VMS program. AMR's
annualized revenue run rate exceeds $15.0 million.

    Robert J. Adamson, MSN's chairman and chief executive officer,
said, "We are pleased to have completed the acquisition of AMR, whose
market-leading vendor management service expertise in the Chicago
marketplace is an asset that we hope to leverage throughout our
national client base. I am excited that the management team behind
AMR's success will remain in place to spearhead this growth initiative
for MSN. Increasingly, clients are expressing an interest in this
process for managing their contingent labor force with solutions that
are effective in controlling costs while providing an environment
conducive to optimal patient care. We believe that the addition of
AMR's VMS portfolio in addition to our current book of VMS business
will establish Medical Staffing Network as one of the largest
providers of healthcare staffing Vendor Management Solutions."

    Fully integrating within an organization, AMR ProNurse's OneSource
VMS streamlines and standardizes every facet of staffing from order
processing, reporting, invoicing, quality initiatives and payment
processes, resulting in vast efficiencies and the best possible cost
savings, quality, and fill ratio performance. The OneSource VMS
program has received national recognition from The Advisory Board
Company (Washington, D.C.) as well as the American College of
Healthcare Executives Congress.

    In commenting on the acquisition, Mark Gallagher, chief executive
officer of AMR ProNurse, added, "We are very excited to announce this
transaction. We believe our innovative approach to helping our clients
manage their supplemental staffing needs and processes through our
OneSource solution will flourish within MSN's national framework. I am
thrilled that the team that built our leadership position in the
Chicago healthcare market will remain in place to serve our current
clients and will have opportunities for growth within MSN. I am
excited to be joining the MSN executive management team."

    About Medical Staffing Network Holdings, Inc.

    Medical Staffing Network Holdings, Inc. is the largest provider of
per diem nurse staffing services in the United States as measured by
revenues. The Company also is a leading provider of travel nurse
staffing services and of allied health professionals, such as
radiology and diagnostic imaging specialists, clinical laboratory
specialists, rehabilitation specialists, pharmacists and respiratory
therapists and other similar healthcare vocations.

    About AMR ProNurse

    AMR ProNurse is the leader in the Chicago healthcare staffing
market through the development of its OneSource vendor management
service for hospital and clinics. The company's clients include some
of the most prestigious healthcare organizations in the country.
Headquartered in downtown Chicago and relying upon a state-of-the-art
technology platform, the company supports clients and healthcare
professionals with the innovative solutions needed in today's
demanding healthcare market.

    Some of the statements in this press release are "forward-looking
statements," as that term is defined in the Private Securities
Litigation Reform Act of 1995. These forward-looking statements
include statements regarding our acquisition of AMR ProNurse.
Forward-looking statements do not relate strictly to historical or
current matters. Rather, forward-looking statements are predictive in
nature and may depend upon or refer to future events, activities or
conditions. Because forward-looking statements relate to matters that
have not yet occurred, these statements are inherently subject to
risks and uncertainties. Many factors could cause our actual
activities or results to differ materially from the activities and
results anticipated in forward-looking statements. These factors
include: our ability to successfully integrate the
business, operations and employees of AMR ProNurse into MSN; our
ability to maintain the operations of AMR ProNurse's VMS program; our
ability to achieve continued revenue growth previously achieved by AMR
ProNurse; and our ability to continue to grow AMR ProNurse's VMS
program. Additional information concerning these and other important
factors can be found within the registrant's filings with the
Securities and Exchange Commission. Forward-looking statements in this
press release should be evaluated in light of these important factors.
Although the registrant believes that these statements are based upon
reasonable assumptions, the registrant cannot provide any assurances
regarding future results. The registrant undertakes no obligation to
revise or update any forward-looking statements, or to make any other
forward-looking statements, whether as a result of new information,
future events or otherwise.

    CONTACT: Medical Staffing Network Holdings, Inc.
             Jeff Yesner, Vice President, Finance, 561-322-1303