UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549


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                                    FORM 10-Q
              (X) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                    For the quarterly period: March 31, 2005

                                       OR
            ( ) TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934
                         COMMISSION FILE NUMBER 0-33505


                            ------------------------


                          LIFE SCIENCES RESEARCH, INC.

             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)
                                    MARYLAND
                 (JURISDICTION OF INCORPORATION OR ORGANIZATION)
                                   52-2340150
                         IRS Employer Identification No.
            PO BOX 2360, METTLERS ROAD, EAST MILLSTONE, NJ 08875-2360
                    (ADDRESS OF PRINCIPAL EXECUTIVE OFFICES)
        REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: 732 649-9961

Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or Section  15(d) of the  Securities  Exchange  Act of
1934  during  the  preceding  12 months  (or for such  shorter  period  that the
registrant  was required to file such report),  and (2) has been subject to such
filing requirements for the past 90 days.

                    Yes X                     No __



Indicate  by check mark  whether  the  registrant  is an  accelerated  filer (as
defined in Rule 12b-2 of the Act)

                    Yes _                     No X

Indicate the number of outstanding shares of each of the Registrant's classes of
common stock as of the latest practicable date.

            12,523,301 Voting Common Stock of $0.01 as of May 3, 2005









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TABLE OF CONTENTS
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PART I          FINANCIAL INFORMATION                                                               Page
                                                                                          
                Item 1      Financial Statements (Unaudited).
                            Condensed Consolidated Statements of Operations for the three
                            months ended March 31, 2005 and 2004.                                      3

                            Condensed Consolidated Balance Sheets at March 31, 2005 and
                            December 31, 2004.                                                         4

                            Condensed Consolidated Statements of Cash Flows for the three
                            months ended March 31, 2005 and 2004.                                      5

                            Notes to Condensed Consolidated Financial Statements.                   6 -9

                Item 2      Management's Discussion and Analysis of Financial Condition and
                            Results of Operations.                                                 10-15

                Item 3      Quantitative and Qualitative Disclosures about Market Risk.               16

                Item 4      Controls and Procedures                                                   16

 PART II        OTHER INFORMATION

                Item 6       Exhibits                                                                 17

                Signature                                                                             17

                Certifications                                                                     18-21









                  LIFE SCIENCES RESEARCH, INC. AND SUBSIDIARIES

PART I            FINANCIAL INFORMATION

ITEM 1            FINANCIAL STATEMENTS



                           CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
                                              Unaudited


                                                                    Three months ended
                                                                         March 31
(Dollars in thousands, except per share data)                         2005                   2004

                                                                                   
Net revenues                                                       $43,294                $37,236
Cost of revenues                                                  (31,082)               (29,435)
                                                                                   ---------------
                                                          -----------------
Gross profit                                                        12,212                  7,801
Selling, general and administrative expenses                       (7,012)                (5,485)
                                                          -----------------        ---------------
Operating income                                                     5,200                  2,316
Interest income                                                         23                     14
Interest expense                                                   (1,783)                (1,576)
Other (expense)/income                                               (732)                  1,355
                                                                                   ---------------
                                                          -----------------
Income before income taxes                                           2,708                  2,109
Income tax expense                                                   (184)                  (716)
                                                                                   ---------------
                                                          -----------------
Net income                                                          $2,524                 $1,393
                                                          -----------------        ---------------
                                                          -----------------        ---------------


Income per common share
- - Basic                                                              $0.20                  $0.12
- - Diluted                                                            $0.17                  $0.11

Weighted average common shares outstanding
- - Basic     (000's)                                                 12,454                 12,040
- - Diluted  (000's)                                                  14,500                 12,241


<FN>

See Notes to Condensed Consolidated Financial Statements.
</FN>







                  LIFE SCIENCES RESEARCH, INC. AND SUBSIDIARIES

                      CONDENSED CONSOLIDATED BALANCE SHEETS



(Dollars in thousands, except per share data)                           March 31,           December 31,
                                                                             2005                   2004
ASSETS                                                                  Unaudited                Audited
                                                                                          
Current assets:
Cash and cash equivalents                                                 $29,899                $33,341
Accounts receivable, net of allowance of $289 and $259 in
    2005 and 2004 respectively                                             26,750                 27,841
Unbilled receivables                                                       10,727                 11,516
Inventories                                                                 1,981                  2,024
Prepaid expenses and other current assets                                   4,214                  2,929
                                                                  ----------------       ----------------
Total current assets                                                       73,571                 77,651

Property and equipment, net                                               109,278                109,999
Goodwill                                                                      885                    901
Unamortized Capital Bonds issue costs                                         217                    271
Deferred income taxes                                                      10,932                 11,253
                                                                  ----------------       ----------------
Total assets                                                             $194,883               $200,075
                                                                  ----------------       ----------------
                                                                  ----------------       ----------------
LIABILITIES AND STOCKHOLDERS' EQUITY/(DEFICIT)
Current liabilities:
Accounts payable                                                          $13,052                $13,547
Accrued payroll and other benefits                                          4,251                  4,024
Accrued expenses and other liabilities                                     18,141                 19,987
Short term debt                                                               258                    719
Fees invoiced in advance                                                   33,208                 37,574
                                                                   ---------------       ----------------
Total current liabilities                                                 $68,910                $75,851

Long-term debt                                                             88,555                 89,685
Pension liabilities                                                        36,032                 36,603
                                                                   ---------------       ----------------
Total liabilities                                                        $193,497               $202,139
                                                                   ---------------       ----------------

Commitments and contingencies
Stockholders' equity/(deficit)
Preferred Stock, $0.01 par value.  Authorized 5,000,000
Issued and outstanding: None                                                    -                      -
Non-Voting Common Stock, $0.01 par value.  Authorized 5,000,000
Issued and outstanding: None                                                    -                      -
Voting Common Stock, $0.01 par value.  Authorized 50,000,000
Issued and outstanding at March 31, 2005: 12,488,639 (December
31, 2004: 12,441,281)                                                         125                    125
Paid in capital                                                            75,744                 75,671
Less: Promissory notes for the issuance of common stock                     (410)                  (697)
Accumulated comprehensive loss                                           (34,158)               (34,724)
Accumulated deficit                                                      (39,915)               (42,439)
                                                                   ---------------       ----------------
Total stockholders' equity /(deficit)                                       1,386                (2,064)
                                                                   ---------------       ----------------
Total liabilities and stockholders' equity /(deficit)                    $194,883               $200,075
                                                                   ---------------       ----------------
<FN>

See Notes to Condensed Consolidated Financial Statements.
</FN>






                  LIFE SCIENCES RESEARCH, INC. AND SUBSIDIARIES

                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                                    Unaudited



                                                                        Three months ended March 31
(Dollars in thousands)                                                        2005                  2004
                                                                                          
Cash flows from operating activities:
Net income                                                                  $2,524                $1,393

Adjustments to reconcile net income to net cash used in
operating activities:
Depreciation and amortization                                                2,349                 2,346
Foreign exchange loss/(gain) on Capital Bonds                                  732               (1,355)
Deferred income taxes                                                          184                   716
Provision for losses on accounts receivable                                     30                    40
Amortization of warrants                                                        86                    57
Amortization of Capital Bonds issue costs                                       50                    46

Changes in operating assets and liabilities:
Accounts receivable, unbilled receivables and prepaid expenses                (87)               (4,784)
Inventories                                                                     12                   200
Accounts payable, accrued expenses and other liabilities                   (1,505)                 (198)
Fees invoiced in advance                                                   (3,798)                 3,011
                                                                   ----------------      ----------------
Net cash provided by operating activities                                     $577                $1,472
                                                                   ----------------      ----------------

Cash flows used in investing activities:
Purchase of property and equipment                                         (3,209)               (2,309)
                                                                   ----------------      ----------------
Net cash used in investing activities                                     $(3,209)              $(2,309)
                                                                   ----------------      ----------------

Cash flows provided by financing activities:
Proceeds from issue of Voting Common Stock                                     360                    18
Repayments of short term borrowings                                          (560)                 (484)
                                                                   ----------------      ----------------
Net cash used in financing activities                                       $(200)                $(466)
                                                                   ----------------      ----------------

Effect of exchange rate changes on cash and cash equivalents                 (610)                 (545)
                                                                   ----------------      ----------------
Decrease in cash and cash equivalents                                      (3,442)               (1,848)
Cash and cash equivalents at beginning of period                            33,341                17,271
                                                                   ----------------      ----------------
Cash and cash equivalents at end of period                                 $29,899               $15,423
                                                                   ----------------      ----------------
Supplementary disclosures

Interest paid in the quarter                                               $2,444                 $2,307

<FN>

See Notes to Condensed Consolidated Financial Statements.

</FN>






                  LIFE SCIENCES RESEARCH, INC. AND SUBSIDIARIES
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
                             March 31, 2005 and 2004
                                    Unaudited

1.       THE COMPANY AND ITS OPERATIONS

Business

Life  Sciences  Research,  Inc.  ("LSR")  and  subsidiaries  (collectively,  the
"Company")  is a  global  contract  research  organization,  offering  worldwide
pre-clinical and non-clinical  testing for biological safety evaluation research
services to pharmaceutical,  biotechnology, agrochemical and industrial chemical
companies.  The Company  serves the rapidly  evolving  regulatory and commercial
requirements to perform safety evaluations on new  pharmaceutical  compounds and
chemical  compounds  contained  within the products that humans use, eat and are
otherwise  exposed  to.  In  addition,  the  Company  tests  the  effect of such
compounds on the  environment and also performs work on assessing the safety and
efficacy of veterinary products.

Organization

LSR,  incorporated in Maryland on July 19, 2001, was formed specifically for the
purpose of acquiring  Life Sciences  Research Ltd (LSR Ltd) formerly  Huntingdon
Life Sciences Group plc  ("Huntingdon"),  which has been in business since 1952.
The Offer was declared  unconditional on January 10, 2002, and LSR completed the
purchase of all  outstanding  ordinary shares of Huntingdon on March 26, 2002 at
which time  Huntingdon  became a wholly owned  subsidiary of LSR (the  "Exchange
Offer").

Under accounting principles generally accepted in the United States ("US GAAP"),
the  Company  whose  stockholders  retain the  majority  interest  in a combined
business must be treated as the acquirer for accounting  purposes.  Accordingly,
the  Exchange  Offer is accounted  for as a reverse  acquisition  for  financial
reporting purposes.  The reverse acquisition is deemed a capital transaction and
the net assets of Huntingdon  (the  accounting  acquirer) are carried forward to
LSR (the legal acquirer and the reporting entity) at their carrying value before
the combination.  Although Huntingdon was deemed to be the acquiring corporation
for financial accounting and reporting purposes,  the legal status of LSR as the
surviving corporation does not change. The relevant acquisition process utilizes
the capital  structure of LSR and the assets and  liabilities  of Huntingdon are
recorded  at  historical  cost.  The equity of LSR is the  historical  equity of
Huntingdon, retroactively restated to reflect the number of shares issued in the
Exchange Offer.

LSR's executive office is based at the Princeton Research Center in New Jersey.





                  LIFE SCIENCES RESEARCH, INC. AND SUBSIDIARIES
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
                             March 31, 2005 and 2004
                                    Unaudited


2.       SIGNIFICANT ACCOUNTING POLICIES

i)       Basis of Presentation

The accompanying  unaudited condensed  consolidated financial statements reflect
all  adjustments  of a normal  recurring  nature,  which are,  in the opinion of
management,  necessary for a fair statement of the results of operations for the
interim periods presented.  The condensed  consolidated financial statements are
unaudited  and are subject to such  year-end  adjustments  as may be  considered
appropriate and should be read in conjunction  with the historical  consolidated
financial  statements  of LSR  years  ended  December  31,  2004,  2003 and 2002
included in LSR's Annual Report on Form 10-K for the fiscal year ended  December
31, 2004.  Operating  results for the three-months  ended March 31, 2005 are not
necessarily  indicative  of the results that may be expected for the year ending
December 31, 2005.

These  financial  statements  have been prepared in accordance  with US GAAP and
under the same accounting principles as the financial statements included in the
Annual Report on Form 10-K. Certain information and footnote disclosures related
thereto  normally  included in the financial  statements  prepared in accordance
with US GAAP have been omitted in accordance with Rule 10-01 of Regulation S-X.

ii)      Stock-Based Compensation

The Company  has stock  option and  stock-based  compensation  plans,  which are
described in detail in our audited consolidated financial statements included in
our Annual Report on Form 10-K for the year ended  December 31, 2004.  Under the
Long Term  Incentive Plan (LTIP),  the Company  granted  362,663  ten-year stock
options to  executives  on June 1, 2004.  All such  options were granted with an
exercise price equal to the market price of the underlying  stock on the date of
the grant.  These options will vest 100% on March 31, 2007 for those  executives
who remain employed with the Company through that date.

Effective  January  1,  2003,  the  Company  adopted  FASB  Statement  No.  148,
Accounting for Stock-Based  Compensation - Transition and Disclosure.  Statement
No. 148 amends FASB Statement No. 123, Accounting for Stock-Based  Compensation,
to  provide,  among  other  things,  prominent  disclosure  of the effects of an
entity's accounting policy with respect to stock-based employee  compensation on
reported  net income and  earnings  per share in annual  and  interim  financial
statements.  The  Company  intends to  continue  to follow  the  disclosure-only
provisions of FASB Statement No. 123 and, accordingly,  will continue to account
for these plans under the recognition and measurement  principles of APB Opinion
No. 25, Accounting for Stock Issued to Employees,  and related  interpretations.
Under APB 25, when stock options are issued with an exercise  price equal to the
market  price of the  underlying  stock on the date of  grant,  no  compensation
expense is recognized.




ii)      Stock-Based Compensation (Cont'd)

No  compensation  cost is recorded for options  granted under the Company's plan
since all options  granted are issued with an exercise price equal to the market
value of the  underlying  common stock on the date of grant,  and employees must
pay for these stock issuances. The following table illustrates the effect on net
income and earnings per share for the three months ended March 31, 2005 and 2004
had the Company applied the fair value recognition  provisions of FASB Statement
No. 123,  Accounting for  Stock-Based  Compensation,  to all of its  stock-based
employee compensation plans.



                                                                                  Three months ended
                                                                                       March 31
                                                                                  2005            2004
(Dollars in thousands, except per share data)
                                                                                            
Net Income, as reported                                                         $2,524            $1,393

Deduct: Total stock-based employee compensation expense determined under
fair value based method for all awards, net of related tax effects                $(91)               $-

                                                                            ----------------- --------------
Pro forma net income                                                            $2,433            $1,393
                                                                            ----------------- --------------

Earnings per share:
Basic - as reported                                                             $0.20             $0.12
Basic - pro forma                                                               $0.20             $0.12
Diluted - as reported                                                           $0.17             $0.11
Diluted - pro forma                                                             $0.17             $0.11



There were no stock options granted during the three months ended March 31, 2005
or 2004. The HLS options  granted prior to 2002 are considered to have no value.
These fair values were estimated using the Black-Scholes  option-pricing  model,
based on the following assumptions:



                                                                                3 Months ended March 31
                                                                                  2005            2004
                                                                                          
Dividend yield                                                                     0%              0%
Volatility                                                                        135%            135%
Risk-free interest rate                                                          4.63%            4.63%
Expected term of options (in years)                                             10 years        10 years








3.       SEGMENT ANALYSIS

The Company  operates  within two segments based on  geographical  markets,  the
United Kingdom and the United States.  The Company has one continuing  activity,
Contract Research.

The analysis of the Company's  net revenues and operating  income by segment for
the three month periods ended March 31, 2005 and March 31, 2004 is as follows:

                                                     Three months ended
                                                          March 31
                                                     2005              2004
(Dollars in thousands)
Net revenues
                          UK                        $34,594          $30,175
                          US
                                                      8,700            7,061
                          Corporate                       -                -
                                             ---------------    ----------------
                                                    $43,294          $37,236
                                             ===============    ================
Operating income
                          UK                         $5,905           $3,057
                          US
                                                      1,078              398
                          Corporate                 (1,783)           (1,139)
                                             ---------------    ----------------
                                                     $5,200           $2,316
                                             ===============    ================

4.       REFINANCING

On March 28, 2002, LSR closed the sale in a private placement of an aggregate of
5,085,334  shares of Voting  Common Stock at a price of $1.50 per share.  Of the
aggregate proceeds of approximately $7.6 million, $4.4 million was in cash, $2.4
million  represented  conversion  into  equity of debt owed to Mr.  Baker  ($2.1
million) and Focused Healthcare Partners ("FHP") ($0.3 million) and $825,000 was
paid with promissory  notes. A net $128,000 of such promissory  notes was repaid
to the end of 2004,  and a further net  $287,000  was repaid to the end of March
2005.


5.       COMMITMENTS AND CONTINGENCIES

(i)  The  Company is party to certain  legal  actions  arising out of the normal
     course of its business. In management's opinion, none of these actions will
     have a material effect on the Company's operations,  financial condition or
     liquidity. No form of proceedings has been brought,  instigated or is known
     to be contemplated against the Company by any governmental agency.

(ii) The Compensation  Committee approved as of June 1, 2004 a performance based
     cash bonus award for  executives.  This award,  issued  under the Long Term
     Incentive Plan (LTIP),  will award cash compensation to select  individuals
     if certain performance goals relating to operations are reached by December
     31,  2006.  The  amount  of the  award  varies  based  upon  the  level  of
     performance,  with a complete  default  of the award if  minimum  operating
     levels are not achieved.

     Management is ratably accruing, as compensation expense, an amount equal to
     the currently estimated cash bonus over the performance period.  Management
     will  re-evaluate  this estimate  periodically  throughout the  performance
     period and, if applicable, will adjust the estimate accordingly.




ITEM 2  MANAGEMENT'S  DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATIONS

1.      RESULTS OF OPERATIONS

a)   Three  months ended March 31, 2005  compared  with three months ended March
     31, 2004.

Net revenues for the three  months  ended March 31 2005 were $43.3  million,  an
increase of 16.3% on net  revenues of $37.2  million for the three  months ended
March 31, 2004.  Excluding the effect of exchange rate  movements,  the increase
was 13.6%. UK net revenues  increased by 14.6%;  at constant  exchange rates the
increase was 11.4%. In the US, net revenues  increased by 23.2%.  This growth in
revenues  reflects  the increase in orders and,  consequently,  backlog over the
last year.  This growth has been  particularly  strong  from the  pharmaceutical
industry,  but  has  been  partly  offset  by a  decline  in  non-pharmaceutical
business.

Cost of revenues for the three  months ended March 31, 2005 were $31.1  million,
an increase of 5.6% on cost of  revenues of $29.4  million for the three  months
ended March 31, 2004.  Excluding  the effects of exchange  rate  movements,  the
increase was 3.2%. UK cost of revenues  increased by 3.4%; at constant  exchange
rates there was a increase of 0.5%.  This low increase in costs  compared to the
increase in revenues  reflects  the  consolidation  of duplicate  facilities  in
response to changes in the market  announced  in the fourth  quarter of 2003 and
implemented  at the end of the  first  quarter  of  2004.  US  cost of  revenues
increased by 14.5% reflecting the growth in revenues.

Selling,  general  and  administrative  expenses  (SG&A)  rose by  27.8% to $7.0
million  for the three  months  ended  March 31,  2005 from $5.5  million in the
corresponding  period in 2004. Excluding the effects of exchange rate movements,
the  increase was 25.5%.  The  increase  was mainly due to  increased  costs for
headquarters  salary  and  bonuses,   higher  insurance  costs,  some  increased
administrative  expenses,  and certain  expenses which are now  classified  into
SG&A.

Net interest expense for the three months ended March 31, 2005 was $1.8 million,
which was $0.2 million higher than the net interest expense for the three months
ended March 31, 2004.  Excluding  the effects of exchange  rate  movements,  the
increase  was  mainly  due to an  increase  in LIBOR and costs  associated  with
foreign currency hedging.

Other  expense in the three months  ended March 31, 2005 was $0.7 million  which
relates to the non-cash foreign exchange  re-measurement loss which arose on the
Convertible  Capital Bonds denominated in US dollars (the functional currency of
the  financial  subsidiary  that  holds  the  bonds  in UK  sterling),  with the
strengthening  of the dollar against  sterling.  In the three months ended March
31, 2004,  other income of $1.4 million related to the non-cash foreign exchange
re-measurement  gain  that  arose on the  Convertible  Capital  Bonds,  with the
weakening of the dollar against sterling.

The income tax expense on income for the three  months  ended March 31, 2005 was
$0.2  million,  which was  primarily  a  non-cash  charge  due to the  company's
operating loss carry forwards. The income tax expense for the three months ended
March 31, 2004 was $0.7  million.  The expense for the three  months ended March
31, 2005 has been reduced by $1.1 million in respect of research and development
tax  credits  in the UK.  The  gross  net  operating  losses in the US are $12.8
million at March 31, 2005;  with gross net  operating  losses in the UK of $63.9
million.



The  overall  net  income for the three  months  ended  March 31,  2005 was $2.5
million  compared to $1.4 million for the three months ended March 31, 2004. The
increase in the net income of $1.1  million is due to an  increase in  operating
income of $2.9  million;  offset by an  increase in  non-cash  foreign  exchange
re-measurement  loss of $2.1 million,  an increase in interest  expenses of $0.2
million and an decrease in the income tax expense of $0.5 million.

Basic  income per common  share was 20 cents,  compared  to 12 cents in the same
period  last  year,  on  the  weighted  average  common  shares  outstanding  of
12,453,633  (2004:  12,039,874).  Diluted income per diluted share was 17 cents,
compared to 11 cents in the same period last year.

Earnings  before  interest,  taxes,  depreciation  and  amortization,  and other
income/(expense)  ("EBITDA")  was $7.5 million for the first quarter of 2005, or
17.4% of revenues, compared with $4.7 million, or 12.5% of revenues for the same
period in the prior year.

The Company  believes that EBITDA  information,  which for this Company excludes
other  income/(expense),  enhances an investor's  understanding of our financial
performance and our ability to satisfy  principal and interest  obligations with
respect  to our  indebtedness.  However,  EBITDA  should  not be  considered  in
isolation or viewed as a substitute for net income, cash flow from operations or
other  measures  of  performance  as defined by  generally  accepted  accounting
principles in the United States.  We understand that while securities  analysts,
lenders  and others in their  evaluation  of  companies  frequently  use EBITDA,
EBITDA as used herein is not necessarily  comparable to other  similarly  titled
captions of other  companies due to potential  inconsistencies  in the method of
calculation.  Management  uses EBITDA to assess  financial  performance and debt
service capabilities. In assessing financial performance, our management reviews
EBITDA as a general indicator of economic performance compared to prior periods.
Because EBITDA excludes interest, income tax, depreciation and amortization, and
other  income/(expense),  EBITDA  provides  an  indicator  of  general  economic
performance  that is not  affected by changes in debt  levels,  fluctuations  in
interest rates or effective tax rates,  levels of depreciation and amortization,
or exchange rate movements on the Capital Bonds.  Management  believes this type
of measurement is useful for comparing general operating performance from period
to period and making  certain  management  decisions.  Nevertheless,  management
recognizes that there are material limitations associated with the use of EBITDA
as  compared  to net  income,  which  reflects  overall  financial  performance,
including the effects of interest, taxes,  depreciation,  amortization and other
income/(expense).

2.       LIQUIDITY & CAPITAL RESOURCES

Bank Loan and Non-Bank Loans

On January 20, 2001, the Company's  non-bank loan of (pound)22.6  million ($42.7
million  approximately),  was  refinanced  by  Stephens'  Group  Inc.  and other
parties.  The loan was  transferred  from  Stephens  Group Inc., to an unrelated
third party  effective  February 11, 2002.  It is now repayable on June 30, 2006
and  interest is payable  quarterly  at LIBOR plus  1.75%.  At the same time the
Company was required to take all  reasonable  steps to sell off some of its real
estate assets through  sale/leaseback  transactions  and/or  obtaining  mortgage
financing  secured by the Company's  real estate assets to discharge  this loan.
The loan is held by Life Sciences Research Ltd (LSR Ltd.), and is secured by the
guarantees  of the  Company's  wholly  owned  subsidiaries,  including  LSR Ltd,
Huntingdon   Life  Sciences  Ltd,  and   Huntingdon   Life  Sciences  Inc.,  and
collateralized by all the assets of these companies.

On October 9, 2001, on behalf of  Huntingdon,  LSR issued to Stephens Group Inc.
warrants  to  purchase  up to  704,425  shares of LSR Voting  Common  Stock at a
purchase price of $1.50 per share. The warrants were subsequently transferred to
an unrelated third party.  The LSR warrants are exercisable at any time and will
expire on October 9, 2011.  These warrants arose out of  negotiations  regarding
the  refinancing of the bank loan by the Stephens Group Inc. in January 2001. In
accordance  with APB Opinion No. 14,  Accounting for  Convertible  Debt and Debt
Issued with Stock  Purchase  Warrants  ("APB 14"), the warrants were recorded at
their pro rata fair values in relation to the  proceeds  received on the date of
issuance.  As a result, the value of the warrants was $430,000.  154,425 of such
warrants were exercised in 2004.



Convertible Capital Bonds

The remainder of the Company's  long term  financing is provided by  Convertible
Capital Bonds repayable on September 25, 2006. At the time of the issue in 1991,
these bonds were for $50 million par and at March 31, 2005,  $46.2  million were
outstanding. They carry interest at a rate of 7.5% per annum, payable biannually
in March and  September.  During 2002,  the Company  repurchased  and  cancelled
$2,410,000  principal  amount of such bonds  resulting  in a $1.2  million  gain
recorded in other  income/expense.  In 2003 the Company further  repurchased and
cancelled  $1,345,000 principal amount of such bonds resulting in a gain of $0.6
million recorded in other  income/expense.  At the current  conversion rate, the
number of shares of Voting Common Stock to be issued on conversion  and exchange
of each unit of $10,000  comprised in a Bond would be 49. The conversion rate is
subject to adjustment in certain circumstances.

Related Party Transactions

On June 11, 2002 LSR issued to Focused  Healthcare  Partners ("FHP"),  an entity
controlled by Andrew Baker, the Company's Chairman and CEO, warrants to purchase
up to 410,914 shares of LSR Voting Common Stock at a purchase price of $1.50 per
share.  The LSR warrants are exercisable at any time and will expire on June 11,
2012. These warrants arose out of negotiations regarding the provision of a $2.9
million loan facility made available to the Company on September 25, 2000 by Mr.
Baker.  This loan was paid in full in 2002. In  accordance  with APB 14 the loan
and  warrants  were  recorded  at their pro rata fair  values in relation to the
proceeds received. As a result, the value of the warrants was $250,000.

Common Shares

On March 28, 2002, LSR closed the sale in a private placement of an aggregate of
5,085,334  shares of Voting  Common Stock at a price of $1.50 per share.  Of the
aggregate proceeds of approximately $7.6 million, $4.4 million was in cash, $2.4
million  represented  conversion  into  equity of debt owed to Mr.  Baker  ($2.1
million) and FHP ($0.3 million) and $825,000 was paid with  promissory  notes. A
net  $128,000  of such  promissory  notes was  repaid to the end of 2004,  and a
further net $287,000 was repaid to the end of March 2005.

Cash flows

During the three  months  ended March 31,  2005,  funds used were $3.4  million,
reducing  cash and cash  equivalents  from $33.3 million at December 31, 2004 to
$29.9 million at March 31, 2005.

Net days sales  outstanding  ("DSOs") at March 31, 2005 were 9 days, an increase
from  the 4 days at  December  31,  2004 (14 days at  March  31,  2004).  DSO is
calculated as a sum of accounts  receivables,  unbilled  receivables and fees in
advance over total  revenue.  Since January  1999,  DSOs at the quarter end have
varied from 1 day to 47 days so they are  currently at a  relatively  low level.
The impact on liquidity from a one-day change in DSO is approximately $484,000.



3.       CRITICAL ACCOUNTING POLICIES

Management's  Discussion  and  Analysis of  Financial  Condition  and Results of
Operations discusses the Company's consolidated financial statements, which have
been prepared in accordance  with US GAAP.  The Company  considers the following
accounting policies to be critical accounting policies.

Revenue recognition

The majority of the  Company's  net revenues  have been earned under  contracts,
which generally range in duration from a few months to three years. Revenue from
these  contracts  is  generally  recognized  over the term of the  contracts  as
services are rendered.  Contracts may contain  provisions for  renegotiations in
the  event of  changes  in the level of work  scope.  Renegotiated  amounts  are
included in net revenue when earned and  realization is assured.  Provisions for
losses to be incurred on contracts are recognized in full in the period in which
it is determined  that a loss will result from  performance  of the  contractual
arrangement.  The Company's customers may terminate most service contracts for a
variety of reasons,  either  immediately  or upon notice of a future  date.  The
contracts  generally  require payments to the Company to recover costs incurred,
including costs to wind down the study,  and payment of fees earned to date, and
in some cases to provide the  Company  with a portion of the fees or income that
would have been earned under the  contract had the contract not been  terminated
early.

Unbilled  receivables  are  recorded  for  revenue  recognized  to date  that is
currently  not  billable to the  customer  pursuant  to  contractual  terms.  In
general,  amounts become billable upon the achievement of certain aspects of the
contract  or  in  accordance  with  predetermined  payment  schedules.  Unbilled
receivables  are  billable  to  customers  within  one year from the  respective
balance sheet date. Fees in advance are recorded for amounts billed to customers
for whom  revenue has not been  recognized  at the  balance  sheet date (such as
upfront  payments  upon  contract   authorization,   but  prior  to  the  actual
commencement of the study).

If the Company does not accurately  estimate the resources required or the scope
of work to be  performed,  or does not manage its projects  properly  within the
planned  periods of time or satisfy its  obligations  under the contracts,  then
future  margins  may be  significantly  and  negatively  affected  or  losses on
existing contracts may need to be recognized.  Any such resulting  reductions in
margins or contract  losses  could,  though it is  unlikely,  be material to the
Company's results of operations.

Use of estimates

The  preparation  of financial  statements in  conformity  with US GAAP requires
management to make estimates and assumptions that affect the reported amounts of
assets and liabilities and disclosure of contingent assets and liabilities as of
the dates of the financial  statements and the results of operations  during the
reporting periods. These also include management estimates in the calculation of
pension  liabilities  covering  discount rates,  return on plan assets and other
actuarial assumptions. Although these estimates are based upon management's best
knowledge of current events and actions,  actual results could differ from those
estimates.

Taxation

The Company  accounts  for income  taxes under the  provisions  of  Statement of
Financial  Accounting  Standards ("SFAS") No. 109, "Accounting For Income Taxes"
("SFAS  109").  SFAS  109  requires  recognition  of  deferred  tax  assets  and
liabilities for the estimated future tax consequences of events  attributable to
differences  between the financial statement carrying amounts of existing assets
and liabilities and their respective tax bases and operating loss and tax credit
carry  forwards.  Deferred tax assets and liabilities are measured using enacted
rates in  effect  for the year in  which  the  differences  are  expected  to be
recovered  or settled.  The effect on  deferred  tax assets and  liabilities  of
changes in tax rates is  recognized in the statement of operations in the period
in which the enactment  rate changes.  Deferred tax assets and  liabilities  are
reduced  through the  establishment  of a valuation  allowance  at such time as,
based on  available  evidence,  it is more likely than not that the deferred tax
assets will not be realized.  While the Company has  considered  future  taxable
income and ongoing prudent and feasible tax planning strategies in assessing the
need  for the  valuation  allowance,  in the  event  that  the  Company  were to
determine  that it would not be able to realize all or part of its net  deferred
tax assets in the future,  an  adjustment  to the  deferred  tax assets would be
charged to income in the period such  determination was made.  Likewise,  should
the Company  determine  that it would be able to realize its deferred tax assets
in the  future  in excess  of its net  recorded  amount,  an  adjustment  to the
deferred tax assets would increase income in the period such  determination  was
made.

Exchange rate fluctuations and exchange controls

The Company operates on a worldwide basis and generally  invoices its clients in
the  currency  of the  country in which it  operates.  Thus,  for the most part,
exposure to exchange rate  fluctuations  is limited as sales are  denominated in
the same currency as costs. Trading exposures to currency  fluctuations do occur
as a result of certain  sales  contracts,  performed  in the UK for US  clients,
which are  denominated  in US dollars and contribute  approximately  7% of total
revenues. Management has decided not to hedge against this exposure.

Also,  exchange  rate  fluctuations  may have an  impact on the  relative  price
competitiveness  of the Company vis a vis  competitors  who trade in  currencies
other than  sterling or dollars.  Such  fluctuations  also have an impact on the
translation of the 7.5% Convertible Capital Bonds payable in September 2006.

The  Company  has  debt  denominated  in both USD and  GBP,  each of which  have
repayment  dates in 2006.  Whereas the Company's  functional  currency is the UK
pound  sterling,  which  results  in the  Company  recording  other  income/loss
associated with USD debt as a function of relative  changes in foreign  exchange
rates,  no decision  has been made as to which  currency  might be chosen as the
basis for replacement financing.  The Company recognizes that there has recently
been   volatility  in  exchange  rates  which  could  have  an  impact  on  such
refinancing.  To manage the volatility relating to these exposures, from time to
time, the Company may enter into certain  derivative  transactions.  The Company
holds and issues derivative financial  instruments for economic hedging purposes
only.  In February  2005 the Company  purchased a currency  hedge against the UK
pound sterling. The call amount of the hedge was (pound)15.0 million and the put
amount was $30.0 million.

Finally,  the  consolidated  financial  statements of LSR are  denominated in US
dollars.  Changes in exchange  rates  between the UK pounds  sterling and the US
dollar will affect the translation of the UK subsidiary's financial results into
US dollars for the purposes of reporting the consolidated financial results. The
process by which each foreign subsidiary's financial results are translated into
US dollars is as follows:  income  statement  accounts are translated at average
exchange  rates for the period;  balance sheet asset and liability  accounts are
translated at end of period exchange rates;  and capital accounts are translated
at historical  exchange  rates and retained  earnings are translated at weighted
average of  historical  rates.  Translation  of the balance sheet in this manner
affects  the  stockholders'  equity  account,  referred  to as  the  accumulated
comprehensive  loss.  Management  has decided not to hedge against the impact of
exposures giving rise to these translation adjustments as such hedges may impact
upon the Company's cash flow compared to the  translation  adjustments  which do
not affect cash flow in the medium term.

Exchange rates for translating sterling into US dollars were as follows:

             At December 31         At March 31         3 months to March 31
                                                          Average rate (1)
   2003          1.7857                1.5807                  1.6031
   2004          1.9199                1.8378                  1.8365
   2005             -                  1.8896                  1.8909

(1)  Based on the average of the exchange rates on each day of each month during
     the period.

On May 3, 2005 the noon buying rate for sterling was (pound)1.00 = $1.891.

The  Company  has  not  experienced  difficulty  in  transferring  funds  to and
receiving funds remitted from those  countries  outside the US or UK in which it
operates and Management expects this situation to continue.

While the UK has not at this time  entered  the  European  Monetary  Union,  the
Company has ascertained  that its financial  systems are capable of dealing with
Euro denominated transactions.

The  following  table  summarizes  the  financial  instruments   denominated  in
currencies other than the US dollar held by LSR and its subsidiaries as of March
31, 2005:



                                                             Expected Maturity Date
                                       2005     2006     2007    2008     2009  Thereafter    Total  Fair
                                                                                                     Value
(In   US   Dollars,   amounts   in thousands)
                                                                            
Cash            - Pound Sterling     14,091        -        -       -        -           -   14,091    14,091
                - Euro                2,743        -        -       -        -           -    2,743     2,743
                - Japanese Yen        1,876        -        -       -        -           -    1,876     1,876
Accounts
receivable      - Pound Sterling     20,156        -        -       -        -           -   20,156    20,156
                - Euro                  606        -        -       -        -           -      606       606
                - Japanese Yen        1,767                 -       -        -           -    1,767     1,767

Debt            - Pound Sterling          -   42,679        -       -        -           -   42,679    42,679
                - Japanese Yen           57        -        -       -        -           -       57        57



4.       LEGAL PROCEEDINGS

The Company is party to certain legal  actions  arising out of the normal course
of its  business.  In  management's  opinion,  none of these actions will have a
material effect on the Company's  operations,  financial condition or liquidity.
No  form  of  proceedings  has  been  brought,  instigated  or  is  known  to be
contemplated against the Company by any governmental agency.

5.       FORWARD LOOKING STATEMENTS

Statements in this management's  discussion and analysis of financial  condition
and results of  operations,  as well as in certain other parts of this Quarterly
Report on Form 10-Q (as well as information included in oral statements or other
written statements made or to be made by the Company) that look forward in time,
are forward looking  statements  made pursuant to the safe harbor  provisions of
the Private Securities Litigation Reform Act of 1995. Forward looking statements
include  statements  concerning plans,  objectives,  goals,  strategies,  future
events or  performance,  expectations,  predictions,  and  assumptions and other
statements  which are other than  statements of historical  facts.  Although the
Company believes such forward-looking  statements are reasonable, it can give no
assurance that any  forward-looking  statements  will prove to be correct.  Such
forward-looking  statements  are subject  to, and are  qualified  by,  known and
unknown risks,  uncertainties and other factors that could cause actual results,
performance or achievements to differ materially from those expressed or implied
by those statements.  These risks,  uncertainties and other factors include, but
are not limited to the Company's  ability to estimate the impact of  competition
and of industry  consolidation  and risks,  uncertainties and other factors more
fully  described  in  the  Company's   filings  with  the  SEC,   including  its
Registration  Statement on Form S-1,  dated July 12, 2002,  and Annual Report on
Form  10-K  for the  year  ended  December  31,  2004,  each as  filed  with the
Securities and Exchange Commission.



ITEM 3            QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

The Company's (pound)22.6 million  (approximately $42.7 million) credit facility
is sterling  denominated and does not contribute to transaction gains and losses
on the income  statement.  Interest  on all  outstanding  borrowings  under this
credit  facility is based upon LIBOR plus a margin and  approximated  6.639% per
annum for the three months  ended March 31, 2005.  At March 31, 2005 this credit
facility was fully drawn down.

In the three  months  ended  March 31,  2005,  a 1% change in LIBOR  would  have
resulted in a fluctuation in interest expense of $107,000.

The  Company  has  debt  denominated  in both USD and  GBP,  each of which  have
repayment  dates in 2006.  Whereas the Company's  functional  currency is the UK
pound  sterling,  which  results  in the  Company  recording  other  income/loss
associated with USD debt as a function of relative  changes in foreign  exchange
rates,  no decision  has been made as to which  currency  might be chosen as the
basis for replacement financing.  The Company recognizes that there has recently
been   volatility  in  exchange  rates  which  could  have  an  impact  on  such
refinancing.  To manage the volatility relating to these exposures, from time to
time, the Company may enter into certain  derivative  transactions.  The Company
holds and issues derivative financial  instruments for economic hedging purposes
only.  In February  2005 the Company  purchased a currency  hedge against the UK
pound sterling. The call amount of the hedge was (pound)15.0 million and the put
amount was $30.0 million.

For the three months ended March 31, 2005,  approximately  73% of the  Company's
net revenues were from outside the United States.

On March 31, 2005, the Company's $46.2 million  principal  amount of Convertible
Capital Bonds is US dollar  denominated,  but is held by a non-US  subsidiary of
the Company.  As a result,  with respect to these bonds, the Company experiences
exchange  related  gains and  losses  which  only has a  non-cash  impact on the
financial  statements,  based on the  movement of  exchange  rates.  Hence,  the
Company does not take any actions to hedge  against  such risks.  The Company is
unable to predict whether it will experience  future gains or future losses from
such exchange-related risks on the bonds.

See Management's  Discussion and Analysis of Financial  Condition and Results of
Operations.


ITEM 4            CONTROLS AND PROCEDURES

As of March 31, 2005 an evaluation  was carried out, under the  supervision  and
with the participation of management,  including our Chief Executive Officer and
Chief Financial Officer, of the effectiveness of the design and operation of our
disclosure controls and procedures  pursuant to Exchange Act Rule 13a-15.  Based
upon that evaluation,  the Chief Executive  Officer and Chief Financial  Officer
concluded that the Company's  disclosure  controls and procedures were effective
as of the  quarter  ended  March 31,  2005 in timely  alerting  them to material
information  relating to the Company  (including its consolidated  subsidiaries)
required to be included in our periodic SEC  filings.  During the quarter  ended
March 31,  2005 there were no  significant  changes in  internal  controls or in
other  factors  that  has  materially  affected,  or are  reasonably  likely  to
materially affect, internal controls over financial reporting.



PART II  OTHER INFORMATION



ITEM 6     EXHIBITS
                          

           Exhibit 31.1         Certification of the Chief Executive Officer

           Exhibit 31.2         Certification of the Chief Financial Officer

           Exhibit 32.1         Certification pursuant to 18 U.S.C. Section 1350
                                as  adopted  pursuant  to Section 906 of the
                                Sarbanes-Oxley Act of 2002 of the Chief
                                Executive Officer

           Exhibit 32.2         Certification pursuant to 18 U.S.C. Section 1350
                                as adopted pursuant to Section 906 of the
                                Sarbanes-Oxley Act of 2002 of the Chief
                                Financial Officer

           Exhibit 99.1         Press Release, dated May 4, 2005, announcing the
                                first quarter earnings results for 2005.



                                    SIGNATURE


Pursuant to the requirements of Section 13 or 15 (d) of the Securities  Exchange
Act of 1934,  this  Quarterly  Report on Form 10-Q has been signed  below by the
following  person on behalf of the  Registrant  and in the capacities and on the
dates indicated.

                           Life Sciences Research Inc.
                                  (Registrant)


By:      /s/ Richard Michaelson

Name:    Richard Michaelson

Title:   CFO & Secretary

Date:    May 4, 2005