UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

- --------------------------------------------------------------------------------

                                    FORM 10-Q
                (X) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

               For the quarterly period ended: September 30, 2005

                                       OR
            ( ) TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934
                         COMMISSION FILE NUMBER 0-33505


                            ------------------------


                          LIFE SCIENCES RESEARCH, INC.

             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)
                                    MARYLAND
                 (JURISDICTION OF INCORPORATION OR ORGANIZATION)
                                   52-2340150
                         IRS Employer Identification No.
            PO BOX 2360, METTLERS ROAD, EAST MILLSTONE, NJ 08875-2360
                    (ADDRESS OF PRINCIPAL EXECUTIVE OFFICES)
        REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: 732 649-9961

Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or Section  15(d) of the  Securities  Exchange  Act of
1934  during  the  preceding  12 months  (or for such  shorter  period  that the
registrant  was required to file such report),  and (2) has been subject to such
filing requirements for the past 90 days.

                        Yes X                     No __

Indicate by check mark whether the registrant is an accelerated filer (as
defined in Rule 12b-2 of the Exchange Act)

                         Yes _                     No X

Indicate by check mark whether the registrant is a shell company (as defined in
Rule 12b-2 of the Exchange Act).

                         Yes _                     No X

Indicate the number of outstanding shares of each of the Registrant's classes of
common stock as of the latest practicable date.

         12,553,251 Voting Common Stock of $0.01 as of November 2, 2005

- --------------------------------------------------------------------------------




TABLE OF CONTENTS



PART I    FINANCIAL INFORMATION                                                                 Page
                                                                                   

           Item 1      Financial Statements (Unaudited).
                       Condensed Consolidated Statements of Operations for the three
                       and nine months ended September 30, 2005 and 2004.                         3

                       Condensed Consolidated Balance Sheets at September 30, 2005 and
                       December 31, 2004.                                                         4

                       Condensed Consolidated Statements of Cash Flows for the nine
                       months ended September 30, 2005 and 2004.                                  5

                       Notes to Condensed Consolidated Financial Statements.                 6 - 10

            Item 2     Management's Discussion and Analysis of Financial Condition
                       and Results of Operations.                                           11 - 20

           Item 3      Quantitative and Qualitative Disclosures about Market Risk.               21

           Item 4      Controls and Procedures                                                   21

 PART II   OTHER INFORMATION

           Item 6      Exhibits                                                                  22

           Signature                                                                             22

           Certifications                                                                   23 - 26






PART I            FINANCIAL INFORMATION

ITEM 1            FINANCIAL STATEMENTS



                 CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
                                    Unaudited


                                                         Three months ended              Nine months ended
                                                            September 30                    September 30

(Dollars in thousands, except per share data)           2005            2004            2005            2004
                                                                                           
Net revenues                                             $43,758         $40,855       $131,993        $116,406
Cost of revenues                                        (31,673)        (29,674)       (95,214)        (87,220)
                                                    -------------    ------------    -----------     -----------
Gross profit                                              12,085          11,181         36,779          29,186
Selling, general and administrative expenses             (6,410)         (6,659)       (20,496)        (18,345)
                                                    -------------    ------------    -----------     -----------
Operating income                                           5,675           4,522         16,283          10,841
Interest income                                               21              13             66              41
Interest expense                                         (2,138)         (1,689)        (5,855)         (4,858)
Other (expense)/income                                   (1,760)           (105)        (5,195)             625
                                                    -------------    ------------    -----------     -----------
Income before income taxes                                 1,798           2,741          5,299           6,649
Income tax expense                                         (649)           (945)        (3,288)         (2,261)
                                                    -------------    ------------    -----------     -----------
Net income                                                $1,149          $1,796         $2,011          $4,388
                                                    -------------    ------------    -----------     -----------


Income per common share
- - Basic                                                    $0.09           $0.15          $0.16           $0.36
- - Diluted                                                  $0.08           $0.13          $0.14           $0.33

Weighted average common shares outstanding
- - Basic     (000's)                                       12,542          12,166         12,506          12,085
- - Diluted  (000's)                                        14,601          13,914         14,521          13,369

<FN>

See Notes to Condensed Consolidated Financial Statements.
</FN>







                  LIFE SCIENCES RESEARCH, INC. AND SUBSIDIARIES
                      CONDENSED CONSOLIDATED BALANCE SHEETS


(Dollars in thousands, except per share data)                       September 30,           December 31,
                                                                             2005                   2004
ASSETS                                                                  Unaudited                Audited
                                                                                          
Current assets:
Cash and cash equivalents                                                 $12,161                $33,341
Accounts receivable, net of allowance of $338 and $259 in
    2005 and 2004 respectively                                             29,581                 27,841
Unbilled receivables                                                       12,531                 11,516
Inventories                                                                 1,733                  2,024
Prepaid expenses and other current assets                                   8,712                  2,929
                                                                  ----------------       ----------------
Total current assets                                                       64,718                 77,651

Property and equipment, net                                               107,709                109,999
Goodwill                                                                    1,032                    901
Unamortized capital bonds issue costs                                         117                    271
Deferred income taxes                                                       7,450                 11,253
                                                                  ----------------       ----------------
Total assets                                                             $181,026               $200,075
                                                                  ----------------       ----------------
                                                                  ----------------       ----------------

LIABILITIES AND STOCKHOLDERS' EQUITY/(DEFICIT)
Current liabilities:
Accounts payable                                                          $15,855                $13,547
Accrued payroll and other benefits                                          3,948                  4,024
Accrued expenses and other liabilities                                     16,928                 19,987
Short-term debt                                                            46,499                    719
Fees invoiced in advance                                                   31,850                 37,574
                                                                   ---------------       ----------------
Total current liabilities                                                 115,080                 75,851

Long-term debt                                                             29,643                 89,685
Pension liabilities                                                        33,760                 36,603
                                                                   ---------------       ----------------
Total liabilities                                                         178,483                202,139
                                                                   ---------------       ----------------

Commitments and contingencies
Stockholders' equity/(deficit)
Preferred Stock, $0.01 par value.  Authorized 5,000,000
Issued and outstanding: None                                                    -                      -
Non-Voting Common Stock, $0.01 par value.  Authorized 5,000,000
Issued and outstanding: None                                                    -                      -
Voting Common Stock, $0.01 par value.  Authorized 50,000,000
Issued and outstanding at September 30, 2005: 12,548,251
(December 31, 2004: 12,441,281)                                               125                    125
Paid in capital                                                            75,841                 75,671
Less: Promissory notes for the issuance of common stock                     (238)                  (697)
Accumulated comprehensive loss                                           (32,757)               (34,724)
Accumulated deficit                                                      (40,428)               (42,439)
                                                                   ---------------       ----------------
Total stockholders' equity /(deficit)                                       2,543                (2,064)
                                                                   ---------------       ----------------
Total liabilities and stockholders' equity /(deficit)                    $181,026               $200,075
                                                                   ---------------       ----------------
<FN>

See Notes to Condensed Consolidated Financial Statements.
</FN>







                  LIFE SCIENCES RESEARCH, INC. AND SUBSIDIARIES
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                                    Unaudited



                                                                          Nine months ended September 30
(Dollars in thousands)                                                        2005                  2004

                                                                                          
Cash flows from operating activities:
Net income                                                                  $2,011                $4,388

Adjustments to reconcile net income to net cash used in
operating activities:
Depreciation and amortization                                                7,229                 7,044
Foreign exchange loss/(gain) on Capital Bonds                                3,765                 (625)
Deferred income taxes                                                        3,288                 2,256
Provision for losses on accounts receivable                                     79                    15
Amortization of warrants                                                       260                   135
Amortization of Capital Bonds issue costs                                      137                   134
Amortization of Financing Costs                                              1,420                     -

Changes in operating assets and liabilities:
Accounts receivable, unbilled receivables and prepaid expenses            (13,880)              (12,661)
Inventories                                                                    131                    71
Accounts payable, accrued expenses and other liabilities                     2,063                 3,020
Fees invoiced in advance                                                   (2,876)                 8,176
                                                                   ----------------      ----------------
                                                                   ----------------      ----------------
Net cash provided by operating activities                                   $3,627               $11,953
                                                                   ----------------      ----------------
                                                                   ----------------      ----------------
Cash flows used in investing activities:
Purchase of property and equipment                                        (12,084)               (7,049)
                                                                   ----------------      ----------------
                                                                   ----------------      ----------------
Net cash used in investing activities                                    $(12,084)              $(7,049)
                                                                   ----------------      ----------------
                                                                   ----------------      ----------------
Cash flows provided by financing activities:
Proceeds from issuance of Voting Common Stock                                  629                   193
Repayments of long-term borrowings                                        (11,106)                     -
Repayments of short-term borrowings                                          (684)                 (838)
                                                                   ----------------      ----------------
                                                                   ----------------      ----------------
Net cash used in financing activities                                    $(11,161)                $(645)
                                                                   ----------------      ----------------
                                                                   ----------------      ----------------

Effect of exchange rate changes on cash and cash equivalents               (1,562)                 (729)
                                                                   ----------------      ----------------
                                                                   ----------------      ----------------
(Decrease)/increase in cash and cash equivalents                          (21,180)                 3,530
Cash and cash equivalents at beginning of period                            33,341                17,271
                                                                   ----------------      ----------------
                                                                   ----------------      ----------------
Cash and cash equivalents at end of period                                 $12,161               $20,801
                                                                   ----------------      ----------------
Supplementary Disclosures

Interest paid in the period                                                $5,392                 $5,261
Taxes paid in the period
           Japan                                                               18                    139
           US                                                                 298                    168

Supplementary Disclosure of Non-Cash Financing Activities:

Proceeds from Sale/Leaseback used to pay off non-bank loan                $30,000                      -

<FN>

See Notes to Condensed Consolidated Financial Statements.
</FN>





                  LIFE SCIENCES RESEARCH, INC. AND SUBSIDIARIES
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
                           September 30, 2005 and 2004
                                    Unaudited


1.       THE COMPANY AND ITS OPERATIONS

Business

Life  Sciences  Research,  Inc.  ("LSR")  and  subsidiaries  (collectively,  the
"Company")  is a  global  contract  research  organization,  offering  worldwide
pre-clinical and non-clinical  testing for biological safety evaluation research
services to pharmaceutical,  biotechnology, agrochemical and industrial chemical
companies.  The Company  serves the rapidly  evolving  regulatory and commercial
requirements to perform safety evaluations on new  pharmaceutical  compounds and
chemical  compounds  contained  within the products that humans use, eat and are
otherwise  exposed  to.  In  addition,  the  Company  tests  the  effect of such
compounds on the  environment and also performs work on assessing the safety and
efficacy of veterinary products.

LSR's executive office is based at the Princeton Research Center in New Jersey.

Organization

LSR,  incorporated in Maryland on July 19, 2001, was formed specifically for the
purpose of acquiring  Life Sciences  Research Ltd (LSR Ltd) formerly  Huntingdon
Life Sciences Group plc  ("Huntingdon"),  which has been in business since 1952.
The Offer was declared  unconditional on January 10, 2002, and LSR completed the
purchase of all outstanding  ordinary shares of Huntingdon on March 26, 2002, at
which time  Huntingdon  became a wholly owned  subsidiary of LSR (the  "Exchange
Offer").

Under accounting principles generally accepted in the United States ("US GAAP"),
the  Company  whose  stockholders  retain the  majority  interest  in a combined
business must be treated as the acquirer for accounting  purposes.  Accordingly,
the  Exchange  Offer is accounted  for as a reverse  acquisition  for  financial
reporting purposes.  The reverse acquisition is deemed a capital transaction and
the net assets of Huntingdon  (the  accounting  acquirer) are carried forward to
LSR (the legal acquirer and the reporting entity) at their carrying value before
the combination.  Although Huntingdon was deemed to be the acquiring corporation
for financial accounting and reporting purposes,  the legal status of LSR as the
surviving corporation does not change. The relevant acquisition process utilizes
the capital  structure of LSR and the assets and  liabilities  of Huntingdon are
recorded  at  historical  cost.  The equity of LSR is the  historical  equity of
Huntingdon, retroactively restated to reflect the number of shares issued in the
Exchange Offer.

On June 14, 2005,  the Company  entered into and  consummated  purchase and sale
agreements   with  Alconbury   Estates  Inc.  and   subsidiaries   (collectively
"Alconbury")  for the  sale  and  leaseback  of the  Company's  three  operating
facilities in Huntingdon and Eye,  England and East  Millstone,  New Jersey (the
"Sale/Leaseback Transaction").  Alconbury is a newly formed company wholly owned
by LSR's  Chairman  and CEO,  Andrew  Baker.  The  total  consideration  paid by
Alconbury for the three properties was $40 million, consisting of $30 million in
cash and a five year, $10 million  variable rate  subordinated  promissory note,
which Alconbury has agreed to make a best effort to repay within twelve months.

The proceeds from the Sale/Leaseback  Transaction (plus additional cash on hand)
were used by the Company to pay in full its  (pound)22.6  million  non-bank debt
(approximately $41.1 million).

In accordance with the provisions of FASB  Interpretation No. 46R (FIN 46R), the
Company will reflect the  consolidation of Alconbury as long as it is considered
the "primary  beneficiary" of Alconbury's  variable interests.  The Company will
not record the gain and loss  associated  with the sale of the  properties,  nor
recognize the associated changes in depreciation,  interest,  and rent expenses,
until FIN 46R  consolidation  accounting no longer  applies.  At that time,  the
Company will record a non-cash loss of approximately $44 million for the sale of
the UK properties,  and a gain of approximately  $6 million,  amortized over the
term of the lease, for the US property.  In addition,  the Company anticipates a
net reduction in its annual  depreciation  charge of approximately $2.7 million,
offset by a net  increase of $0.5  million in interest  and rent  expenses.  The
Company  anticipates  that it will  no  longer  be the  primary  beneficiary  of
Alconbury when the $10 million subordinated promissory note has been repaid.

2.       SIGNIFICANT ACCOUNTING POLICIES

i)       Basis of Presentation

The accompanying  unaudited condensed  consolidated financial statements reflect
all  adjustments  of a normal  recurring  nature,  which are,  in the opinion of
management,  necessary for a fair statement of the results of operations for the
interim periods presented.  The condensed  consolidated financial statements are
unaudited  and are subject to such  year-end  adjustments  as may be  considered
appropriate and should be read in conjunction  with the historical  consolidated
financial  statements  of LSR  years  ended  December  31,  2004,  2003 and 2002
included in LSR's Annual Report on Form 10-K for the fiscal year ended  December
31, 2004.  Operating  results for the  three-month  and nine month periods ended
September  30, 2005 are not  necessarily  indicative  of the results that may be
expected for the year ending December 31, 2005.

These  financial  statements  have been prepared in accordance  with US GAAP and
under the same accounting principles as the financial statements included in the
Annual Report on Form 10-K. Certain information and footnote disclosures related
thereto  normally  included in the financial  statements  prepared in accordance
with US GAAP have been omitted in accordance with Rule 10-01 of Regulation S-X.

ii)      Stock-Based Compensation

The Company  has stock  option and  stock-based  compensation  plans,  which are
described in detail in our audited consolidated financial statements included in
our Annual Report on Form 10-K for the year ended  December 31, 2004.  Under the
Long Term  Incentive Plan (LTIP),  the Company  granted  362,663  ten-year stock
options to  executives  on June 1, 2004.  All such  options were granted with an
exercise price equal to the market price of the underlying  stock on the date of
the grant.  These options will vest 100% on March 31, 2007 for those  executives
who remain employed with the Company through that date.

Effective  January  1,  2003,  the  Company  adopted  FASB  Statement  No.  148,
Accounting for Stock-Based  Compensation - Transition and Disclosure.  Statement
No. 148 amends FASB Statement No. 123, Accounting for Stock-Based  Compensation,
to  provide,  among  other  things,  prominent  disclosure  of the effects of an
entity's accounting policy with respect to stock-based employee  compensation on
reported  net income and  earnings  per share in annual  and  interim  financial
statements.  The  Company  intends to  continue  to follow  the  disclosure-only
provisions of FASB Statement No. 123 and, accordingly,  will continue to account
for these plans under the recognition and measurement  principles of APB Opinion
No. 25, Accounting for Stock Issued to Employees,  and related  interpretations.
Under APB 25, when stock options are issued with an exercise  price equal to the
market  price of the  underlying  stock on the date of  grant,  no  compensation
expense is recognized.




ii)      Stock-Based Compensation (cont'd)

No  compensation  cost is recorded for options  granted under the Company's plan
since all options  granted are issued with an exercise price equal to the market
value of the  underlying  common stock on the date of grant,  and employees must
pay for these stock issuances. The following table illustrates the effect on net
income and earnings per share for the three and nine months ended September,  30
2005 and 2004 had the Company applied the fair value  recognition  provisions of
FASB Statement No.123,  Accounting for Stock-Based  Compensation,  to all of its
stock-based employee compensation plans.




                                               Three months ended September 30   Nine months ended September 30
                                               -------------------------------   ------------------------------
                                                    2005             2004           2005           2004
                                                                                      
(Dollars in thousands, except per share data)
Net Income, as reported                            $1,149           $1,796         $2,011         $4,388

Deduct: Total stock-based employee
compensation expense determined under fair
value based method for all awards, net of
related tax effects                                $(101)           $(40)          $(340)          $(71)

Pro forma net income                               $1,048           $1,756         $1,671         $4,317

Earnings per share:

Basic - as reported                                 $0.09           $0.15           $0.16          $0.36
Basic - pro forma                                   $0.08           $0.14           $0.13          $0.36
Diluted - as reported                               $0.08           $0.13           $0.14          $0.33
Diluted - pro forma                                 $0.07           $0.13           $0.12          $0.32


There were no grants of stock  options  during the three months ended  September
30, 2005 (nor the three months ended September 30, 2004). The per share weighted
average fair value of stock options  granted was $7.74 and $1.82 during the nine
months ended September 30, 2005 and 2004  respectively.  The HLS options granted
prior to 2002 are considered to have no value.  These fair values were estimated
using  the   Black-Scholes   option-pricing   model,   based  on  the  following
assumptions:

                                                Nine months ended
                                                  September 30
                                              2005            2004

Dividend yield                                 0%              0%
Volatility                                     56%            40%
Risk-free interest rate                       3.93%          3.72%
Expected term of options                    10 years        10 years







3.       SEGMENT ANALYSIS

The Company  operates  within two segments based on  geographical  markets,  the
United  Kingdom  and the  United  States,  and incurs  corporate  administrative
expenses. The Company has one continuing activity, Contract Research.

The analysis of the Company's  net revenues and operating  income by segment for
the three and nine month periods ended September 30, 2005 and September 30, 2004
is as follows:



                                         Three months ended             Nine months ended
                                            September 30                   September 30
                                        2005            2004           2005            2004
(Dollars in thousands)
                                                                         

Net revenues
                  UK                      $33,673         $32,944       $103,763         $93,709
                  US
                                           10,085           7,911         28,230          22,697
                  Corporate                     -               -              -               -
                                       -----------     -----------    -----------     -----------
                                                                                      -----------
                                          $43,758         $40,855       $131,993        $116,406
                                       ===========     ===========    ===========     ===========

Operating income
                  UK                       $5,183          $4,906        $16,905         $12,394
                  US                        1,792           1,069          4,437           2,248
                  Corporate               (1,300)         (1,453)        (5,059)         (3,801)
                                       -----------     -----------    -----------     -----------
                                           $5,675          $4,522        $16,283         $10,841
                                       ===========     ===========    ===========     ===========
                                       ===========     ===========    ===========     ===========



4.       REFINANCING

On March 28, 2002, LSR closed the sale in a private placement of an aggregate of
5,085,334  shares of Voting  Common Stock at a price of $1.50 per share.  Of the
aggregate proceeds of approximately $7.6 million, $4.4 million was in cash, $2.4
million  represented  conversion  into  equity of debt owed to Mr.  Baker  ($2.1
million) and Focused Healthcare Partners ("FHP") ($0.3 million) and $825,000 was
paid with promissory  notes. A net $128,000 of such promissory  notes was repaid
to the  end of  2004,  and a  further  net  $459,000  was  repaid  to the end of
September 2005.

On June 14, 2005, the Company entered into and  consummated  the  Sale/Leaseback
Transaction with Alconbury.  Alconbury is a newly formed company wholly owned by
LSR's Chairman and CEO, Andrew Baker. The total  consideration paid by Alconbury
for the three  properties was $40 million,  consisting of $30 million cash and a
five year,  $10  million  variable  rate  subordinated  promissory  note,  which
Alconbury  has agreed to make a best effort to repay within twelve  months.  The
Company  has  agreed  to  pay  the   expenses   incurred  by  Alconbury  in  the
Sale/Leaseback Transaction of approximately $4.8 million, subject to Alconbury's
obligation to reimburse those expenses in the future.  Such reimbursement  shall
be made in equal  installments  in each year of the five-year  period  beginning
June 14, 2008, the third  anniversary of the closing date of the  Sale/Leaseback
Transaction.

Due to the consolidation  resulting from the Company's  adoption of FIN 46R, the
Company's financial statements reflect a loan by an unrelated third party in the
aggregate principal amount of $30 million. This loan has a term date of June 14,
2006, with the right to extend the term up to an additional one-year.  Alconbury
intends to refinance  this debt on a long-term  basis prior to the maturity date
of June  14,  2006.  However,  if the  long  term  financing  is not  available,
Alconbury  has  advised the Company  that it intends to  exercise  the  one-year
renewal option, and accordingly,  has classified the loan as long-term debt. The
loan,  which  carries an annual  interest rate of 15%, has been secured by first
priority lien on all the assets, including the facilities,  of Alconbury, and is
also  personally  guaranteed by the owner of  Alconbury.  This loan is currently
payable in twelve monthly  installments of interest only, with a balloon payment
of $30 million due on June 14, 2006.

As part of the Sale/Leaseback  Transaction,  the Company (through  subsidiaries)
entered  into  thirty year leases with  Alconbury  for each  facility,  with two
five-year renewal options. Base aggregate annual rent for the facilities is $4.9
million  (approximately $1.8 million in the US and approximately $3.1 million in
the UK) which amount will increase by 3% each year for the UK facilities  and by
an amount equal to the annual US consumer price index for the US facility. Under
the terms of the leases,  no  security  deposit was  initially  required,  but a
three-month  security  deposit  will be  required  at such time  that  Alconbury
refinances its current financing arrangements.  Additionally, because the leases
are "triple net" leases,  LSR will also pay for all of the costs associated with
the operation of the facilities,  including  costs such as insurance,  taxes and
maintenance.

Since the Sale/Leaseback  Transaction was with a related party (Mr. Baker, LSR's
Chairman and CEO and the owner of Alconbury),  an Independent Committee of LSR's
Board of  Directors  (the  "Committee")  was formed to analyze and  consider the
proposed  Sale/Leaseback  Transaction.  The Committee was comprised of the three
independent directors of LSR: Gabor Balthazar, Afonso Junqueiras and Yaya Sesay.
The Committee retained  independent legal and financial advisors to assist it in
its analysis.  The Committee and LSR's senior  management (other than Mr. Baker)
negotiated the key terms and provisions of the  Sale/Leaseback  Transaction with
Alconbury.  The  Committee  also  obtained  appraisals  of the  facilities  from
independent real estate appraisal firms.

The proceeds from the Sale/Leaseback  Transaction (plus additional cash on hand)
were used by the Company to pay in full its  (pound)22.6  million  non-bank debt
(approximately $41.1 million).

In accordance with the provisions of FASB  Interpretation No. 46R (FIN 46R), the
Company will reflect the  consolidation of Alconbury as long as it is considered
the "primary  beneficiary" of Alconbury's  variable interests.  The Company will
not record the gain and loss  associated  with the sale of the  properties,  nor
recognize the associated changes in depreciation,  interest,  and rent expenses,
until FIN 46R  consolidation  accounting no longer  applies.  At that time,  the
Company will record a non-cash loss of approximately $44 million for the sale of
the UK properties,  and a gain of approximately  $6 million,  amortized over the
term of the lease, for the US property.  In addition,  the Company anticipates a
net reduction in its annual  depreciation  charge of approximately  $2.7million,
offset by a net  increase of $0.5  million in interest  and rent  expenses.  The
Company  anticipates  that it will  no  longer  be the  primary  beneficiary  of
Alconbury when the $10 million subordinated promissory note has been repaid.


5.       COMMITMENTS AND CONTINGENCIES

     (i)  The  Company  is party to certain  legal  actions  arising  out of the
          normal course of its business.  In management's opinion, none of these
          actions  will  have a  material  effect on the  Company's  operations,
          financial  condition or  liquidity.  No form of  proceedings  has been
          brought, instigated or is known to be contemplated against the Company
          by any governmental agency.

     (ii) The Compensation  Committee  approved as of June 1, 2004 a performance
          based cash bonus award for  executives.  This award,  issued under the
          Long Term  Incentive  Plan  (LTIP),  will award cash  compensation  to
          select individuals if certain performance goals relating to operations
          are reached by December 31, 2006. The amount of the award varies based
          upon the level of performance, with a complete default of the award if
          minimum operating levels are not achieved.

          Management is ratably  accruing,  as compensation  expense,  an amount
          equal to the  currently  estimated  cash  bonus  over the  performance
          period.   Management  will  re-evaluate  this  estimate   periodically
          throughout the performance period and, if applicable,  will adjust the
          estimate accordingly.





ITEM 2   MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
         OF OPERATIONS

1.       RESULTS OF OPERATIONS

a)   Three  months ended  September  30, 2005  compared  with three months ended
     September 30, 2004.

Net revenues for the three months ended September 30 2005 were $43.8 million, an
increase of 7.1% on net  revenues of $40.9  million for the three  months  ended
September  30,  2004.  Excluding  the effect of  exchange  rate  movements,  the
increase was 8.6%. UK net revenues increased by 2.4%; at constant exchange rates
the  increase  was 4.3%.  US net  revenues  increased  by 26.6%.  The  growth in
revenues  in both the UK and the US  reflects  the  increase  in orders from the
pharmaceutical industry.

Cost of  revenues  for the three  months  ended  September  30,  2005 were $31.7
million,  an increase of 6.7% on cost of revenues of $29.7 million for the three
months  ended  September  30,  2004.  Excluding  the  effects of  exchange  rate
movements,  the increase  was 8.2%.  UK cost of revenues  increased by 2.7%;  at
constant  exchange  rates  there was a  increase  of 4.5%.  US cost of  revenues
increased by 23.6%.  The increase in the cost of revenues in both the UK and the
US reflects the growth in revenues.

Selling,  general and  administrative  expenses (SG&A) decreased by 3.8% to $6.4
million for the three months ended  September  30, 2005 from $6.7 million in the
corresponding  period in 2004. Excluding the effects of exchange rate movements,
the decrease was 8.1%. The decrease was mainly due to lower incentive plan costs
and exchange gains, offset in part by higher salary and insurance costs.

Net  interest  expense for the three months  ended  September  30, 2005 was $2.1
million,  which was $0.4 million  higher than the net  interest  expense for the
three months ended  September  30, 2004.  Excluding the effects of exchange rate
movements,  the increase was mainly due to an increase in costs  associated with
the  unrelated  third  party  loan of  Alconbury,  which  is  included  in these
consolidated financial statements due to the Company's adoption of FIN 46R, when
compared to the  interest  associated  with the non bank loan that was repaid on
June 14, 2005.

Other  expense in the three  months  ended  September  30, 2005 was $1.8 million
reflecting a non-cash foreign exchange re-measurement loss of $0.6 million which
arose on the Convertible Capital Bonds denominated in US dollars (the functional
currency of the financial subsidiary that holds the bonds is UK sterling),  with
the strengthening of the dollar against sterling,  and finance  arrangement fees
of $1.2 million.  The finance  arrangement  fees represent the  amortization  of
costs  incurred by Alconbury as part of the sale and leaseback  transaction.  In
the three months ended September 30, 2004, other expense of $0.1 million related
to  the  non-cash  foreign  exchange  re-measurement  loss  that  arose  on  the
Convertible  Capital  Bonds,  with  the  strengthening  of  the  dollar  against
sterling.

The income tax expense for the three  months ended  September  30, 2005 was $0.6
million.  The income tax expense for the three months ended  September 30, 2004,
was $0.9 million.  Net operating losses are $61.2 million at September 30, 2005;
with net  operating  losses  in the US of $6.4  million  and with net  operating
losses in the UK of $54.8 million.





The net income for the three  months ended  September  30, 2005 was $1.1 million
compared to $1.8  million for the three  months ended  September  30, 2004.  The
decrease in the net income of $0.7  million is due to an  increase in  operating
income of $1.2  million;  offset by an  increase in  non-cash  foreign  exchange
re-measurement  loss of $0.6 million,  finance arrangement fees of $1.2 million,
an increase in  interest  expenses of $0.4  million and a decrease in the income
tax expense of $0.3 million.

Basic income per common share for the three months ended  September 30, 2005 was
9 cents,  compared  to 15 cents  income in the same  period  last  year,  on the
weighted  average common shares  outstanding of 12,541,912  (2004:  12,165,643).
Diluted  income per diluted share for the three months ended  September 30, 2005
was 8 cents, compared to 13 cents income in the same period last year.

Excluding  the Other  Expense  items  described  above  related  to the  finance
arrangement fees, the non-cash foreign exchange losses,  and related tax effect,
non-GAAP  net income for the three  months  ended  September  30,  2005 was $3.2
million, or $0.22 per fully diluted share (non-GAAP), compared with $1.9 million
or $0.13 per fully diluted share for the same period in the prior year.

Earnings  before  interest,  taxes,  depreciation  and  amortization,  and other
income/(expense)  ("EBITDA")  was  $8.1  million  for  the  three  months  ended
September 30, 2005, or 18.5% of revenues,  compared with $7.0 million,  or 17.0%
of revenues for the same period in the prior year.

This  Quarterly  Report  on Form  10-Q  contains  non-GAAP  financial  measures,
including  EBITDA and  non-GAAP  earnings per share which  exclude,  among other
items,   gains  or  losses   associated  with  the  non-cash   foreign  exchange
remeasurement loss pertaining to the Company's Convertible Capital Bonds and one
time charges.  We exclude these items in the non-GAAP financial measures because
they are  outside  our normal  operations.  We  believe  that the  inclusion  of
non-GAAP  financial  measures  in  this  Quarterly  Report  on Form  10-Q  helps
investors to gain a meaningful  understanding of our core operating  results and
future prospects,  and is consistent with how management  measures and forecasts
the  Company's  performance  and  debt  service  capabilities,  especially  when
comparing  such results to prior  periods or  forecasts.  Non-GAAP  results also
allow  investors  to compare the  Company's  operations  against  the  financial
results of other  companies  in the  industry  who  similarly  provide  non-GAAP
results.  The non-GAAP  financial  measures included in this Quarterly Report on
Form 10-Q are not meant to be considered superior to or a substitute for results
of operations prepared in accordance with GAAP.  Reconciliations of the non-GAAP
financial  measures  used in this  Quarterly  Report  on Form  10-Q to the  most
directly  comparable  GAAP financial  measures are set forth in the text of this
Quarterly Report on Form 10-Q and other public filings, and can also be found on
the Company's website at www.lsrinc.net.

b)   Nine  months  ended  September  30 2005  compared  with nine  months  ended
     September 30, 2004

Net revenues for the nine months ended  September 30, 2005 were $132.0  million,
an increase of 13.4% on net revenues of $116.4 million for the nine months ended
September  30,  2004.  Excluding  the effect of  exchange  rate  movements,  the
increase was 12.3%.  UK net revenues  increased by 10.8%;  at constant  exchange
rates the  increase was 9.4%.  This growth in revenues  reflects the increase in
orders  and,  consequently,  backlog  over the last year,  principally  from the
pharmaceutical  industry.  Also  reflected  in the  nine  months  were  revenues
associated  with the post life phase of an  unusually  large number of long-term
studies,  much of which was  subcontracted  due to  capacity  constraints.  This
increased revenues for the nine months by approximately $1.8 million. In the US,
net revenues  increased by 24.0%.  The growth in revenues in the US reflects the
increase in orders from the pharmaceutical industry.

Cost of  revenues  for the nine  months  ended  September  30,  2005 were  $95.2
million,  an increase of 9.2 % on cost of revenue of $87.2  million for the nine
months  ended  September  30,  2004.  Excluding  the  effects of  exchange  rate
movements,  the increase  was 8.1%.  UK cost of revenues  increased by 6.8%;  at
constant exchange rates the increase was 5.5%. Reflected in the nine months were
costs of $0.8 million  associated with  subcontracting the post life phase of an
abnormal  number of long-term  studies.  US cost of revenues  increased by 18.7%
reflecting the growth in revenues.

Selling,  general  and  administrative  expenses  (SG&A)  rose by 11.7% to $20.5
million for the nine months ended  September  30, 2005 from $18.3 million in the
corresponding  period in 2004. Excluding the effects of exchange rate movements,
the increase  was 9.8%.  This  increase  was mainly due to increased  salary and
insurance costs.

Net  interest  expense for the nine  months  ended  September  30, 2005 was $5.8
million,  which was $1.0 million  higher than the net  interest  expense for the
nine months ended  September  30, 2004.  Excluding  the effects of exchange rate
movements,  the  increase  was mainly  due to an  increase  in LIBOR,  the costs
associated with foreign  currency  hedging,  and the increased cost of financing
since the repayment of the non-bank loan.

Other  expense in the nine months  ended  September  30,  2005 was $5.2  million
reflecting a non-cash foreign exchange  remeasurement loss of $3.8 million which
arose on the Convertible Capital Bonds denominated in US dollars (the functional
currency of the financial subsidiary that holds the bonds is UK sterling),  with
the strengthening of the dollar against sterling,  and finance  arrangement fees
of $1.4 million.  The finance  arrangement  fees represent the  amortization  of
costs  incurred by Alconbury as part of the sale and leaseback  transaction.  In
the nine months ended  September 30, 2004,  other income of $0.6 million related
to  the  non-cash  foreign  exchange   remeasurement  gain  that  arose  on  the
Convertible Capital Bonds with the weakening of the dollar against sterling.

The income tax  expense for the nine months  ended  September  30, 2005 was $3.3
million.  This expense  includes $2.4 million in respect of the tax liability on
the sale of the  Company's  US  facility.  The income tax  expense  for the nine
months ended September 30, 2004 was $2.3 million.

The net income for the nine months  ended  September  30, 2005 was $2.0  million
compared to $4.4  million for the nine months  ended  September  30,  2004.  The
decrease  in the  net  income  of  $2.4  million  is due to an  increase  in the
operating  income of $5.4  million;  offset by a decrease  in  non-cash  foreign
exchange  remeasurement loss of $4.4 million,  finance  arrangement fees of $1.4
million, an increase in interest expense of $1.0 million, and an increase in the
income tax expense of $1.0 million.

Basic income per common share for the nine months ended  September  30, 2005 was
16 cents,  compared  to 36 cents  income in the same  period  last year,  on the
weighted  average common shares  outstanding of 12,505,798  (2004:  12,085,311).
Diluted  income per diluted  share for the nine months ended  September 30, 2005
was 14 cents, compared to 33 cents income for the same period in the prior year.

Excluding  the Other  Expense  items  described  above  related  to the  finance
arrangement fees, the non-cash foreign exchange losses,  and related tax effect,
and the transaction related tax charges, non-GAAP net income for the nine months
ended  September  30,  2005 was $9.4  million or $0.65 per fully  diluted  share
(non-GAAP),  compared with $3.9 million or $0.29 per fully diluted share for the
same period in the prior year.

Earnings  before  interest,  taxes,  depreciation  and  amortization  and  other
income/(expense)  ("EBITDA")  was  $23.5  million  for  the  nine  months  ended
September 30, 2005 or 17.8% of revenues, compared with $17.9 million or 15.4% of
revenues for the same period in the prior year.

2.       LIQUIDITY & CAPITAL RESOURCES

Non-Bank Loans

On  January  20,  2001,  the  Company's  non-bank  loan of  (pound)22.6  million
($41.1million  approximately),  was  refinanced by Stephens Group Inc. and other
parties.  The loan was  transferred  from  Stephens  Group Inc., to an unrelated
third party  effective  February 11, 2002. It was repayable on June 30, 2006 and
interest was payable quarterly at LIBOR plus 1.75%. At the same time the Company
was  required to take all  reasonable  steps to sell off some of its real estate
assets through  sale/leaseback  transactions and/or obtaining mortgage financing
secured by the Company's real estate assets to discharge this loan. The loan was
held by Life Sciences Research Ltd (LSR Ltd.), and was secured by the guarantees
of the Company's wholly owned  subsidiaries,  including LSR Ltd, Huntingdon Life
Sciences Ltd, and Huntingdon Life Sciences Inc., and  collateralized  by all the
assets of these companies.  On June 14, 2005 this non-bank loan was fully repaid
using the proceeds from the Sale/Leaseback Transaction and cash on hand.

On October 9, 2001, on behalf of  Huntingdon,  LSR issued to Stephens Group Inc.
warrants to purchase  704,425  shares of LSR Voting  Common  Stock at a purchase
price of $1.50 per share.  The  warrants  were  subsequently  transferred  to an
unrelated  third party.  The LSR warrants are  exercisable  at any time and will
expire on October 9, 2011.  These warrants arose out of  negotiations  regarding
the  refinancing of the bank loan by the Stephens Group Inc. in January 2001. In
accordance  with APB Opinion No. 14,  Accounting for  Convertible  Debt and Debt
Issued with Stock  Purchase  Warrants  ("APB 14"), the warrants were recorded at
their pro rata fair values in relation to the  proceeds  received on the date of
issuance.  As a result, the value of the warrants was $430,000.  154,425 of such
warrants were exercised in 2004.

On June 14, 2005, the Company entered into and  consummated  the  Sale/Leaseback
Transaction with Alconbury.  Alconbury is a newly formed company wholly owned by
LSR's Chairman and CEO, Andrew Baker. The total  consideration paid by Alconbury
for the three  properties was $40 million,  consisting of $30 million cash and a
five year,  $10  million  variable  rate  subordinated  promissory  note,  which
Alconbury  has agreed to make a best effort to repay within twelve  months.  The
Company  has  agreed  to  pay  the   expenses   incurred  by  Alconbury  in  the
Sale/Leaseback Transaction of approximately $4.8 million, subject to Alconbury's
obligation to reimburse those expenses in the future.  Such reimbursement  shall
be made in equal  installments in each year of the five-year period beginning on
June 14, 2008, the third  anniversary of the closing date of the  Sale/Leaseback
Transaction.

As part of the Sale/Leaseback  Transaction,  the Company (through  subsidiaries)
entered into  thirty-year  leases with  Alconbury  for each  facility,  with two
five-year renewal options. Base aggregate annual rent for the facilities is $4.9
million  (approximately $1.8 million in the US and approximately $3.1 million in
the UK) which amount will increase by 3% each year for the UK facilities  and by
an amount equal to the annual US consumer price index for the US facility. Under
the terms of the leases,  no  security  deposit was  initially  required,  but a
three-month  security  deposit  will be  required  at such time  that  Alconbury
refinances its current financing arrangements.  Additionally, because the leases
are "triple net" leases,  LSR will also pay for all of the costs associated with
the operation of the facilities,  including  costs such as insurance,  taxes and
maintenance.

Since the Sale/Leaseback  Transaction was with a related party (Mr. Baker, LSR's
Chairman and CEO and the owner of Alconbury),  an Independent Committee of LSR's
Board of  Directors  (the  "Committee")  was formed to analyze and  consider the
proposed  Sale/Leaseback  Transaction.  The Committee was comprised of the three
independent directors of LSR: Gabor Balthazar, Afonso Junqueiras and Yaya Sesay.
The Committee retained independent legal and financial advisors to assist in its
analysis.  The  Committee  and LSR's senior  management  (other than Mr.  Baker)
negotiated the key terms and provisions of the  Sale/Leaseback  Transaction with
Alconbury.  The  Committee  also  obtained  appraisals  of the  facilities  from
independent real estate appraisal firms.

The proceeds from the Sale/Leaseback  Transaction (plus additional cash on hand)
were used by the Company to pay in full its  (pound)22.6  million  non-bank debt
(approximately $41.1 million).

In accordance with the provisions of FASB  Interpretation No. 46R (FIN 46R), the
Company will reflect the  consolidation of Alconbury as long as it is considered
the "primary  beneficiary" of Alconbury's  variable interests.  The Company will
not record the gain and loss  associated  with the sale of the  properties,  nor
recognize the associated changes in depreciation,  interest,  and rent expenses,
until FIN 46R  consolidation  accounting no longer  applies.  At that time,  the
Company will record a non-cash loss of approximately $44 million for the sale of
the UK properties,  and a gain of approximately  $6 million,  amortized over the
term of the lease, for the US property.  In addition,  the Company anticipates a
net reduction in its annual  depreciation  charge of approximately $2.7 million,
offset by a net  increase of $0.5  million in interest  and rent  expenses.  The
Company  anticipates  that it will  no  longer  be the  primary  beneficiary  of
Alconbury when the $10 million subordinated promissory note has been repaid.

Due to the consolidation  resulting from the Company's  adoption of FIN 46R, the
Company's financial statements reflect a loan by an unrelated third party in the
aggregate principal amount of $30 million. This loan has a maturity date of June
14,  2006,  with the right to extend  the term one  additional  year.  Alconbury
intends to refinance  this debt on a long-term  basis prior to the maturity date
of June  14,  2006.  However,  if the  long  term  financing  is not  available,
Alconbury  has  advised the Company  that it intends to  exercise  the  one-year
renewal option, and accordingly,  has classified the loan as long-term debt. The
loan,  which  carries an annual  interest rate of 15%, has been secured by first
priority lien on all the assets, including the facilities,  of Alconbury, and is
also  personally  guaranteed by the owner of  Alconbury.  This loan is currently
payable in twelve monthly  installments of interest only, with a balloon payment
of $30 million due on June 14, 2006.

Convertible Capital Bonds

The  remainder of the  Company's  financing is provided by  Convertible  Capital
Bonds  repayable on September 25, 2006. At the time of the issue in 1991,  these
bonds were for $50 million par and at  September  30, 2005,  $46.2  million were
outstanding. They carry interest at a rate of 7.5% per annum, payable biannually
in March and  September.  During 2002,  the Company  repurchased  and  cancelled
$2,410,000  principal  amount of such bonds  resulting  in a $1.2  million  gain
recorded in other  income/expense.  In 2003 the Company further  repurchased and
cancelled  $1,395,000 principal amount of such bonds resulting in a gain of $0.6
million recorded in other  income/expense.  At the current  conversion rate, the
number of shares of Voting Common Stock to be issued on conversion  and exchange
of each unit of $10,000  comprised in a Bond would be 49. The conversion rate is
subject to adjustment in certain circumstances.



Related Party Transactions

On June 11, 2002 LSR issued to Focused  Healthcare  Partners ("FHP"),  an entity
controlled by Andrew Baker, the Company's Chairman and CEO, warrants to purchase
up to 410,914 shares of LSR Voting Common Stock at a purchase price of $1.50 per
share.  The LSR warrants are exercisable at any time and will expire on June 11,
2012. These warrants arose out of negotiations regarding the provision of a $2.9
million loan facility made available to the Company on September 25, 2000 by Mr.
Baker.  This loan was paid in full in 2002. In  accordance  with APB 14 the loan
and  warrants  were  recorded  at their pro rata fair  values in relation to the
proceeds received. As a result, the value of the warrants was $250,000.

On June 14, 2005,  the Company  completed the  Sale/Leaseback  Transaction  with
Alconbury, a company formed by Mr Baker, LSR's Chairman and CEO. The Company has
agreed  to  pay  the  expenses  incurred  by  Alconbury  in  the  Sale/Leaseback
Transaction of approximately $4.8 million,  subject to Alconbury's obligation to
reimburse  those  expenses in the future.  Such  reimbursement  shall be made in
equal  instalments  in each year of the five-year  period  beginning on June 14,
2008,  the  third  anniversary  of  the  closing  date  of  the   Sale/Leaseback
Transaction.

Alconbury  has  received  an  interest  free  loan of  $250,000,  which has been
included in accrued  expenses and other  liabilities,  from Andrew Baker,  LSR's
Chairman and CEO.

Common Shares

On March 28, 2002, LSR closed the sale in a private placement of an aggregate of
5,085,334  shares of Voting  Common Stock at a price of $1.50 per share.  Of the
aggregate proceeds of approximately $7.6 million, $4.4 million was in cash, $2.4
million  represented  conversion  into  equity of debt owed to Mr.  Baker  ($2.1
million) and FHP ($0.3 million) and $825,000 was paid with  promissory  notes. A
net  $128,000  of such  promissory  notes was  repaid to the end of 2004,  and a
further net $459,000 was repaid to the end of September 2005.

Cash flows

During the three months ended September 30, 2005,  funds used were $3.2 million,
reducing cash and cash  equivalents from $15.4 million at June 30, 2005 to $12.2
million at September 30, 2005.

In the nine months to September 30, 2005 funds used were $21.1 million, reducing
cash and cash  equivalents  from $33.3  million in  December  31,  2004 to $12.2
million at September 30, 2005.

Net days sales  outstanding  ("DSOs") at  September  30,  2005 were 21 days,  an
increase from the 13 days at June 30, 2005,  and 4 days at December 31, 2004 (20
days at September 30, 2004). DSO is calculated as a sum of accounts receivables,
unbilled receivables and fees in advance over total revenue. Since January 1999,
DSOs at the quarter end have varied from 4 days to 47 days so they are currently
at a mid range level.  The impact on liquidity  from a one-day  change in DSO is
approximately $485,000.

New York Stock Exchange Listing Application

On August 22, 2005 the Company  announced that its listing  application had been
accepted  by the New  York  Stock  Exchange  ("NYSE")  and that  trading  of the
Company's  common  stock on the NYSE was  expected to begin on  September  7. On
September  7, 2005 the  Company  announced  that the NYSE had  "postponed"  such
listing.  The Company has  received no further  information  from the NYSE since
September 7 about when or whether such postponement will be resolved.



3.       CRITICAL ACCOUNTING POLICIES

Management's  Discussion  and  Analysis of  Financial  Condition  and Results of
Operations discusses the Company's consolidated financial statements, which have
been prepared in accordance  with US GAAP.  The Company  considers the following
accounting policies to be critical accounting policies.

Revenue recognition

The majority of the  Company's  net revenues  have been earned under  contracts,
which generally range in duration from a few months to three years. Revenue from
these  contracts  is  generally  recognized  over the term of the  contracts  as
services are rendered.  Contracts may contain  provisions for  renegotiations in
the  event of  changes  in the level of work  scope.  Renegotiated  amounts  are
included in net revenue when earned and  realization is assured.  Provisions for
losses to be incurred on contracts are recognized in full in the period in which
it is determined  that a loss will result from  performance  of the  contractual
arrangement.  The Company's customers may terminate most service contracts for a
variety of reasons,  either  immediately  or upon notice of a future  date.  The
contracts  generally  require payments to the Company to recover costs incurred,
including costs to wind down the study,  and payment of fees earned to date, and
in some cases to provide the  Company  with a portion of the fees or income that
would have been earned under the  contract had the contract not been  terminated
early.

Unbilled  receivables  are  recorded  for  revenue  recognized  to date  that is
currently  not  billable to the  customer  pursuant  to  contractual  terms.  In
general,  amounts become billable upon the achievement of certain aspects of the
contract  or  in  accordance  with  predetermined  payment  schedules.  Unbilled
receivables  are  billable  to  customers  within  one year from the  respective
balance sheet date. Fees in advance are recorded for amounts billed to customers
for whom  revenue has not been  recognized  at the  balance  sheet date (such as
upfront  payments  upon  contract   authorization,   but  prior  to  the  actual
commencement of the study).

If the Company does not accurately  estimate the resources required or the scope
of work to be  performed,  or does not manage its projects  properly  within the
planned  periods of time or satisfy its  obligations  under the contracts,  then
future  margins  may be  significantly  and  negatively  affected  or  losses on
existing contracts may need to be recognized.  Any such resulting  reductions in
margins or contract  losses  could,  though it is  unlikely,  be material to the
Company's results of operations.

Use of estimates

The  preparation  of financial  statements in  conformity  with US GAAP requires
management to make estimates and assumptions that affect the reported amounts of
assets and liabilities and disclosure of contingent assets and liabilities as of
the dates of the financial  statements and the results of operations  during the
reporting periods. These also include management estimates in the calculation of
pension  liabilities  covering  discount rates,  return on plan assets and other
actuarial assumptions. Although these estimates are based upon management's best
knowledge of current events and actions,  actual results could differ from those
estimates.

Taxation

The Company  accounts  for income  taxes under the  provisions  of  Statement of
Financial  Accounting  Standards ("SFAS") No. 109, "Accounting For Income Taxes"
("SFAS  109").  SFAS  109  requires  recognition  of  deferred  tax  assets  and
liabilities for the estimated future tax consequences of events  attributable to
differences  between the financial statement carrying amounts of existing assets
and liabilities and their respective tax bases and operating loss and tax credit
carry  forwards.  Deferred tax assets and liabilities are measured using enacted
rates in  effect  for the year in  which  the  differences  are  expected  to be
recovered  or settled.  The effect on  deferred  tax assets and  liabilities  of
changes in tax rates is  recognized in the statement of operations in the period
in which the enactment  rate changes.  Deferred tax assets and  liabilities  are
reduced  through the  establishment  of a valuation  allowance  at such time as,
based on  available  evidence,  it is more likely than not that the deferred tax
assets will not be realized.  While the Company has  considered  future  taxable
income and ongoing prudent and feasible tax planning strategies in assessing the
need  for the  valuation  allowance,  in the  event  that  the  Company  were to
determine  that it would not be able to realize all or part of its net  deferred
tax assets in the future,  an  adjustment  to the  deferred  tax assets would be
charged to income in the period such  determination was made.  Likewise,  should
the Company  determine  that it would be able to realize its deferred tax assets
in the  future  in excess  of its net  recorded  amount,  an  adjustment  to the
deferred tax assets would increase income in the period such  determination  was
made.

Consolidation of Alconbury

In accordance with the provisions of FASB  Interpretation No. 46R (FIN 46R), the
Company will reflect the  consolidation of Alconbury as long as it is considered
the "primary  beneficiary" of Alconbury's  variable interests.  The Company will
not record the gain and loss  associated  with the sale of the  properties,  nor
recognize the associated changes in depreciation,  interest,  and rent expenses,
until FIN 46R  consolidation  accounting no longer  applies.  At that time,  the
Company will record a non-cash loss of approximately $44 million for the sale of
the UK properties,  and a gain of approximately  $6 million,  amortized over the
term of the lease, for the US property.  In addition,  the Company anticipates a
net reduction in its annual  depreciation  charge of approximately  $2.7million,
offset by a net  increase of $0.5  million in interest  and rent  expenses.  The
Company  anticipates  that it will  no  longer  be the  primary  beneficiary  of
Alconbury when the $10 million subordinated promissory note has been repaid.

Exchange rate fluctuations and exchange controls

The Company operates on a worldwide basis and generally  invoices its clients in
the  currency  of the  country in which it  operates.  Thus,  for the most part,
exposure to exchange rate  fluctuations  is limited as sales are  denominated in
the same currency as costs. Trading exposures to currency  fluctuations do occur
as a result of certain  sales  contracts,  performed  in the UK for US  clients,
which are  denominated  in US dollars and contribute  approximately  6% of total
revenues. Management has decided not to hedge against this exposure.

Also,  exchange  rate  fluctuations  may have an  impact on the  relative  price
competitiveness  of the Company vis a vis  competitors  who trade in  currencies
other than  sterling or dollars.  Such  fluctuations  also have an impact on the
translation of the 7.5% Convertible Capital Bonds payable in September 2006.

The Company  has debt  denominated  in USD,  whereas  the  Company's  functional
currency is the UK pound sterling,  which results in the Company recording other
income/loss  associated  with USD debt as a  function  of  relative  changes  in
foreign  exchange rates. No decision has been made as to which currency might be
chosen as the basis for replacement financing. The Company recognizes that there
has recently  been  volatility  in exchange  rates which could have an impact on
such  refinancing.  To manage the volatility  relating to these exposures,  from
time to time, the Company may enter into certain  derivative  transactions.  The
Company holds and issues derivative  financial  instruments for economic hedging
purposes  only.  There  were no  derivative  financial  instruments  in place on
September 30, 2005.

Finally,  the  consolidated  financial  statements of LSR are  denominated in US
dollars.  Changes in exchange  rates  between the UK pounds  sterling and the US
dollar will affect the translation of the UK subsidiary's financial results into
US dollars for the purposes of reporting the consolidated financial results. The
process by which each foreign subsidiary's financial results are translated into
US dollars is as follows:  income  statement  accounts are translated at average
exchange  rates for the period;  balance sheet asset and liability  accounts are
translated at end of period exchange rates;  and capital accounts are translated
at historical  exchange  rates and retained  earnings are translated at weighted
average of  historical  rates.  Translation  of the balance sheet in this manner
affects  the  stockholders'  equity  account,  referred  to as  the  accumulated
comprehensive  loss.  Management  has decided not to hedge against the impact of
exposures giving rise to these translation adjustments as such hedges may impact
upon the Company's cash flow compared to the  translation  adjustments  which do
not affect cash flow in the medium term.




Exchange rates for translating sterling into US dollars were as follows:



            At December 31       At September 30     3 months to September 30    9 months to September 30
                                                         Average rate (1)            Average rate (1)
                                                                             
   2003         1.7857               1.6614                   1.6111                      1.6111
   2004         1.9199               1.8096                   1.8192                      1.8209
   2005            -                 1.7691                   1.7854                      1.8437
<FN>

(1)      Based on the average of the exchange rates on each day of each month during the period.
</FN>


On November 2, 2005 the noon buying rate for sterling was (pound)1.00 = $1.7755

The  Company  has  not  experienced  difficulty  in  transferring  funds  to and
receiving funds remitted from those  countries  outside the US or UK in which it
operates and Management expects this situation to continue.

While the UK has not at this time  entered  the  European  Monetary  Union,  the
Company has ascertained  that its financial  systems are capable of dealing with
Euro denominated transactions.

The  following  table  summarizes  the  financial  instruments   denominated  in
currencies  other  than the US  dollar  held by LSR and its  subsidiaries  as of
September 30, 2005:


                                                             Expected Maturity Date
                                       2005     2006     2007    2008     2009  Thereafter    Total  Fair
                                                                                                     Value
(In US Dollars, amounts in thousands)

                                                                                           
Cash            - Pound Sterling      3,512        -        -       -        -           -    3,512     3,512
                - Euro                  605        -        -       -        -           -      605       605
                - Japanese Yen        2,325        -        -       -        -           -    2,325     2,325
Accounts
receivable      - Pound Sterling     20,834        -        -       -        -           -   20,834    20,834
                - Euro                2,033        -        -       -        -           -    2,033     2,033
                - Japanese Yen        2,080                 -       -        -           -    2,080     2,080

Debt            - Pound Sterling          -        -        -       -        -           -        -         -
                - Japanese Yen           87        -        -       -        -           -       87        87



4.       LEGAL PROCEEDINGS

The Company is party to certain legal  actions  arising out of the normal course
of its  business.  In  management's  opinion,  none of these actions will have a
material effect on the Company's  operations,  financial condition or liquidity.
No  form  of  proceedings  has  been  brought,  instigated  or  is  known  to be
contemplated against the Company by any governmental agency.




5.       FORWARD LOOKING STATEMENTS

Statements in this management's  discussion and analysis of financial  condition
and results of  operations,  as well as in certain other parts of this Quarterly
Report on Form 10-Q (as well as information included in oral statements or other
written statements made or to be made by the Company) that look forward in time,
are forward looking  statements  made pursuant to the safe harbor  provisions of
the Private Securities Litigation Reform Act of 1995. Forward looking statements
include  statements  concerning plans,  objectives,  goals,  strategies,  future
events or  performance,  expectations,  predictions,  and  assumptions and other
statements  which are other than  statements of historical  facts.  Although the
Company believes such forward-looking  statements are reasonable, it can give no
assurance that any  forward-looking  statements  will prove to be correct.  Such
forward-looking  statements  are subject  to, and are  qualified  by,  known and
unknown risks,  uncertainties and other factors that could cause actual results,
performance or achievements to differ materially from those expressed or implied
by those statements.  These risks,  uncertainties and other factors include, but
are not limited to the Company's  ability to estimate the impact of  competition
and of industry  consolidation  and risks,  uncertainties and other factors more
fully  described  in  the  Company's   filings  with  the  SEC,   including  its
Registration  Statement on Form S-1,  dated July 12, 2002,  and Annual Report on
Form  10-K  for the  year  ended  December  31,  2004,  each as  filed  with the
Securities and Exchange Commission.



ITEM 3            QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

The Company's (pound)22.6 million (approximately  $41.1million on June 14, 2005)
non-bank loan was sterling  denominated  and did not  contribute to  transaction
gains and losses on the income  statement.  Interest on this  non-bank  loan was
based upon LIBOR plus a margin and  approximated  6.66% per annum for the period
ended June 14, 2005.  On June 14, 2005 this non-bank loan was fully repaid using
the proceeds from the Sale/Leaseback transaction and cash on hand.

The Company  has debt  denominated  in USD,  whereas  the  Company's  functional
currency is the UK pound sterling,  which results in the Company recording other
income/loss  associated  with USD debt as a  function  of  relative  changes  in
foreign  exchange rates. No decision has been made as to which currency might be
chosen as the basis for replacement financing. The Company recognizes that there
has recently  been  volatility  in exchange  rates which could have an impact on
such  refinancing.  To manage the volatility  relating to these exposures,  from
time to time, the Company may enter into certain  derivative  transactions.  The
Company holds and issues derivative  financial  instruments for economic hedging
purposes  only.  There  were no  derivative  financial  instruments  in place on
September 30, 2005.

For the three and nine months ended  September 30, 2005,  approximately  73% and
74%  respectively,  of the  Company's  net revenues were from outside the United
States.

On  September  30,  2005,  the  Company's  $46.2  million  principal  amount  of
Convertible  Capital  Bonds is US  dollar  denominated,  but is held by a non-US
subsidiary of the Company. As a result, with respect to these bonds, the Company
experiences  exchange  related gains and losses which only has a non-cash impact
on the financial statements, based on the movement of exchange rates. Unlike the
Company's  position to hedge against the debt mentioned  above, the Company does
not take any  action to hedge  against  the risk of  currency  fluctuation  with
regard to the Capital  Bonds..  The Company is unable to predict whether it will
experience future gains or future losses from such exchange-related risks on the
bonds.

See Management's  Discussion and Analysis of Financial  Condition and Results of
Operations.


ITEM 4            CONTROLS AND PROCEDURES

As of September 30, 2005 an evaluation  was carried out,  under the  supervision
and with the participation of management,  including our Chief Executive Officer
and Chief Financial Officer, of the effectiveness of the design and operation of
our  disclosure  controls and  procedures  pursuant to Exchange Act Rule 13a-15.
Based upon that  evaluation,  the Chief  Executive  Officer and Chief  Financial
Officer  concluded that the Company's  disclosure  controls and procedures  were
effective as of the quarter ended  September 30, 2005 in timely alerting them to
material  information  relating  to  the  Company  (including  its  consolidated
subsidiaries)  required to be included in our periodic  SEC filings.  During the
quarter ended  September 30, 2005 there were no significant  changes in internal
controls or in other factors that has  materially  affected,  or are  reasonably
likely to materially affect, internal controls over financial reporting.





PART II  OTHER INFORMATION

ITEM 6     EXHIBITS

     Exhibit 31.1  Certification of the Chief Executive Officer

     Exhibit 31.2  Certification of the Chief Financial Officer

     Exhibit 32.1  Certification  pursuant to 18 U.S.C.  Section 1350 as adopted
                   pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 of
                   the Chief Executive Officer

     Exhibit 32.2  Certification  pursuant to 18 U.S.C.  Section 1350 as adopted
                   pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 of
                   the Chief Financial Officer

     Exhibit 99.1  Press Release,  dated  November 3, 2005, announcing the third
                   quarter earnings results for 2005.


                                    SIGNATURE


Pursuant to the requirements of Section 13 or 15 (d) of the Securities  Exchange
Act of 1934,  this  Quarterly  Report on Form 10-Q has been signed  below by the
following  person on behalf of the  Registrant  and in the capacities and on the
dates indicated.

                           Life Sciences Research Inc.
                                  (Registrant)


By:      /s/ Richard Michaelson

Name:    Richard Michaelson

Title:   CFO

Date:    November 4, 2005