DIRECTOR STOCK OPTION AGREEMENT

     THIS  STOCK  OPTION  AGREEMENT  is made as of the  8th day of  June,  2006,
between Life Sciences Research, Inc., a Maryland corporation (hereinafter called
the  "Corporation"),   and  Gabor  Balthazar,  a  director  of  the  Corporation
(hereinafter called the "Option Holder").

1.   Grant of Option.  In accordance  with the 2001 Equity  Incentive  Plan, the
     Corporation  hereby  grants to the  Option  Holder  the  right and  option,
     hereinafter  called the "Option",  to purchase an aggregate of 2,500 shares
     (the  "Shares") of the  Corporation's  $0.01 par value voting  common stock
     (such  number  being  subject to  adjustment  as  provided  in  paragraph 7
     hereof),  on the terms and  conditions  herein set forth.  Such  shares are
     granted in connection with Option Holder's service as a Board member.  Such
     Option  shall vest as  follows:  Fifty (50%)  Percent of the Option  herein
     granted  (for up to 1,250  shares)  shall vest and may be  exercised  on or
     after the date hereof,  and the remaining Fifty (50%) Percent of the Option
     herein  granted (for up to 1,250 shares) shall vest and may be exercised on
     or after June 8, 2007 (unless  terminated  earlier  pursuant to paragraph 6
     hereof).

2.   Purchase  Price.  The  purchase  price of the Shares  covered by the Option
     shall be ten dollars and seventy-five cents ($10.75) per Share.

3.   Term of Option.  Subject to paragraph 8 hereof,  the Option  granted hereby
     shall be  exercisable  in whole or in part in accordance  with paragraph 1.
     The Option  Holder's  right to exercise  the  aforementioned  Option  shall
     expire ten (10)  years  from the date  hereof.  Unless  terminated  earlier
     pursuant to paragraph 6 hereof,  any Option not exercised  within such time
     specified of the date hereof shall terminate.

4.   Transferability.  Subject to  paragraph 5 hereof,  the Option  Holder shall
     have the right to  freely  assign,  transfer,  pledge  or  hypothecate  the
     Option.

5.   Disclosure  and Risk.  The Option  Holder  represents  and  warrants to the
     Corporation as follows:

     (a)  The  Shares  will be  acquired  by the  Option  Holder  for the Option
          Holder's own account,  for  investment  and not with a view to, or for
          resale in connection with, any distribution or public offering thereof
          within the  meaning of the  Securities  Act of 1933,  as amended  (the
          "Securities Act").

     (b)  As of the date of the grant and of  exercise,  because of his position
          as a director of the Corporation, and as a result of inquiries made by
          him and information furnished to him by the Corporation, Option Holder
          has  and  will  have  all  information  necessary  for  him to make an
          informed investment decision.

     Each certificate representing the Shares shall, if applicable,  be endorsed
with the following or a substantially similar legend:


     "THE  SECURITIES  EVIDENCED BY THIS  CERTIFICATE  HAVE NOT BEEN  REGISTERED
     UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE SECURITIES ACT'), AND MAY
     NOT BE SOLD,  TRANSFERRED,  ASSIGNED  OR  HYPOTHECATED  UNLESS  THERE IS AN
     EFFECTIVE  REGISTRATION  STATEMENT UNDER SUCH ACT COVERING SUCH SECURITIES,
     OR THE  CORPORATION  RECEIVES AN OPINION OF COUNSEL FOR THE HOLDER OF THESE
     SECURITIES,  REASONABLY SATISFACTORY TO THE CORPORATION,  STATING THAT SUCH
     SALE,  TRANSFER,  ASSIGNMENT OR HYPOTHECATION  MAY BE MADE PURSUANT TO RULE
     144,  PROMULGATED UNDER THE SECURITIES ACT, OR IS OTHERWISE EXEMPT FROM THE
     REGISTRATION  AND  PROSPECTUS   DELIVERY   REQUIREMENTS  OF  SUCH  ACT  AND
     APPLICABLE STATE SECURITIES LAWS."

     The  Corporation  need not allow a transfer of any of the Shares unless one
of  the  conditions  specified  in  the  foregoing  legend  is  satisfied.   The
Corporation  may also  instruct its transfer  agent not to allow the transfer of
any of the Shares unless one of the conditions specified in the foregoing legend
is satisfied.

     Any legend endorsed on a certificate pursuant to the foregoing language and
the stop transfer  instructions with respect to such Shares shall be removed and
the  Corporation  shall promptly issue a certificate  without such legend to the
holder  thereof if the  Shares are  registered  under the  Securities  Act and a
prospectus  meeting  the  requirements  of Section 10 of the  Securities  Act is
available or if the holder provides the  Corporation  with an opinion of counsel
for such holder of the Shares reasonably satisfactory to the Corporation, to the
effect that a public  sale,  transfer or  assignment  of such Shares may be made
without registration.

6.      Termination of Service as a Director; Death.

     (a)  In the event that the Option  Holder  shall  cease to be a director of
          the Corporation for any reason whatsoever, the Option may be exercised
          by the Option  Holder (to the extent that the Option Holder shall have
          been  entitled  to do so as of  the  date  of the  termination  of his
          directorship  with the  Corporation) at any time within 365 days after
          such  termination  but in  any  event  not  later  than  the  date  of
          expiration  of the Option  term.  So long as the Option  Holder  shall
          continue to be a director of the Corporation,  the Option shall not be
          affected by any change of duties or  position.  Nothing in this Option
          Agreement shall confer upon the Option Holder any right to continue as
          a director of the Corporation.

     (b)  In the event that the Option  Holder dies prior to  exercising  all or
          any portion of the Option,  the Option may be  exercised by the estate
          of the Option  Holder (to the extent that the Option Holder shall have
          been entitled to do so) at any time within 365 days after the death of
          the  Option  Holder,  but in any  event  not  later  than  the date of
          expiration of the Option term.

7.   Changes in Capital Structure.  If all or any portion of the Option shall be
     exercised  subsequent to any share  dividend,  split-up,  recapitalization,
     merger,  consolidation,  combination  or  exchange  of shares,  separation,
     reorganization, or liquidation occurring after the date hereof, as a result
     of which  shares of any class  shall be issued in  respect  of  outstanding
     Shares or Shares  shall be changed  into the same or a different  number of
     shares of the same or  another  class or  classes,  the  person or  persons
     exercising the Option shall receive, for the aggregate price paid upon such
     exercise, the aggregate number and class of shares which, if the Shares (as
     authorized  at the date  hereof) had been  purchased at the date hereof for
     the same aggregate  price (on the basis of the price per share set forth in
     paragraph  2 hereof) and had not been  disposed  of, such person or persons
     would be holding at the time of such  exercise as a result of such purchase
     and  all  such  share  dividends,  split-ups,  recapitalizations,  mergers,
     consolidations,   combinations   or  exchanges   of  shares,   separations,
     reorganizations,  or liquidations;  provided,  however,  that no fractional
     shares shall be issued upon any such exercise, and the aggregate price paid
     shall be  appropriately  reduced  on account  of any  fractional  share not
     issued. In no event shall any adjustments be made to the Option as a result
     of the issuance or redemption of securities of the  Corporation for cash or
     other  consideration,  or upon the exercise of any conversion rights of any
     securities of the Corporation.

8.   Method of Exercising  Option.  Subject to the terms and  conditions of this
     Option  Agreement,  the Option may be  exercised  by written  notice to the
     Secretary  of the  Corporation,  at its  principal  office  or  such  other
     location as may be  designated by the  Secretary of the  Corporation.  Such
     notice  shall state the  election to exercise  the Option and the number of
     Shares in  respect of which it is being  exercised,  and shall be signed by
     the person or persons so  exercising  the  Option.  The notice of  election
     shall be  accompanied  by this  Agreement  and payment of the full purchase
     price for the Shares being  purchased.  As an alternative to payment of the
     purchase  price for the  Shares,  the Option  may,  at the  election of the
     holder,  be converted  into the nearest whole number of Shares equal to (X)
     the product of (A) the number of Shares  subject to this option and (B) the
     excess,  if any,  of (1) the  closing  market  price  per  Share  as of the
     exercise date over (2) the Purchase Price (as adjusted through the exercise
     date), divided by (Y) the closing market price per Share as of the exercise
     date.  The   Corporation   shall  deliver  a  certificate  or  certificates
     representing Shares as soon as practicable after the notice of election has
     been received.  In the event the Option shall be exercised by any person or
     persons  other than the Option  Holder,  the  notice of  election  shall be
     accompanied by appropriate  proof of the right of such person or persons to
     exercise the Option.  All Shares that shall be purchased  upon the exercise
     of the Option as provided herein shall be fully paid and nonassessable.

9.   Change in Control.  A Change in Control of the  Corporation  (as defined in
     the 2001 Equity  Incentive  Plan) shall have the effect upon the Option set
     forth in Section 9 of the 2001 Equity Incentive Plan.

10.  Optionee Not a Shareholder.  The Option Holder under this Option,  as such,
     shall not be entitled by any reason of this Option to any rights whatsoever
     as a shareholder of the Corporation.


11.  General Provisions.

     (a)  The  Corporation  shall at all  times  during  the term of the  Option
          reserve and keep available such number of Shares as will be sufficient
          to satisfy the  requirements of this Option  Agreement,  shall pay all
          fees  and  expenses   necessarily   incurred  by  the  Corporation  in
          connection  therewith,  and shall use its best  efforts to comply with
          all laws and regulations  which, in the reasonable  opinion of counsel
          for the Corporation, are applicable thereto.

     (b)  This Agreement  shall be governed by and construed in accordance  with
          the laws of the State of  Maryland  other than its  conflicts  of laws
          provisions.

     (c)  Any notice to be given hereunder by either party to the other shall be
          in writing and shall be given either by personal  delivery or by mail,
          registered or certified,  postage prepaid,  return receipt  requested,
          addressed  to the other party at the  respective  addresses  set forth
          below their  signatures to this Agreement,  or at any other address as
          such party may hereafter specify in writing.

     (d)  This  Agreement  sets  forth  the  entire  agreement  of  the  parties
          concerning the subject matter hereto, and no other  representations or
          warranties, express or implied, other than those contained herein, and
          no amendments or modifications hereto, shall be binding unless made in
          writing and signed by the parties hereto.

     (e)  The  waiver by either  party of a breach of any term or  provision  of
          this  Agreement  shall not  operate or be  construed  as a waiver of a
          subsequent  breach of the same provision or of the breach of any other
          term or provision of this Agreement.

     (f)  As used herein,  the  masculine  gender shall include the feminine and
          the neuter  genders,  the neuter shall  include the  masculine and the
          feminine  genders,  the  singular  shall  include the plural,  and the
          plural shall include the singular.

     (g)  The headings in this Agreement are solely for convenience of reference
          and shall be given no effect in the construction or  interpretation of
          this Agreement.

     (h)  The  invalidity or  enforceability  of any provision of this Agreement
          shall not affect the validity or enforceability of any other provision
          of this Agreement, which shall remain in full force and effect.

     IN WITNESS WHEREOF,  the Corporation has caused this Option Agreement to be
duly executed by its officer  thereunto duly  authorized,  and the Option Holder
has  hereunto  set his hand and  seal,  all as of the day and year  first  above
written.

                                     OPTION HOLDER

                                        /s/ Gabor Balthazar
                                     ------------------------------
                                     Name:     Gabor Balthazar
                                     Address:




                                     LIFE SCIENCES RESEARCH, INC.


                                     By:   /s/ Mark Bibi
                                     ------------------------------
                                     Name:      Mark Bibi
                                     Title:     General Counsel
                                     Address: