UNITED STATES SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                    Form 8-K

                                 Current Report

                       Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934


       Date of Report: (Date of earliest event reported): December 6, 2006


              Life Sciences Research, Inc. ("LSR" or the "Company")
              -----------------------------------------------------
             (Exact name of registrant as specified in its charter)


                                    Maryland
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                 (State or other jurisdiction of incorporation)


        0-33505                                        52-2340150
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(Commission File Number)                (I.R.S. Employer Identification Number)



Mettlers Road, East Millstone, NJ                        08875
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(Address of principal executive offices)               (Zip Code)


Registrant's telephone number, including area code:  (732) 649-9961



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(Former name or former address, if changed since last report)


Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instructions A.2. below):

[    ] Written communications  pursuant to Rule 425 under the Securities Act (17
       CFR 230.425)

[    ] Soliciting  material  pursuant to Rule 14a-12 under the Exchange Act (17
       CFR 240.14a-12)

[    ] Pre-commencement  communications  pursuant  to Rule  14d-2(b)  under the
         Exchange Act (17 CFR 240.14d-2(b))

[    ] Pre-commencement  communication  pursuant  to Rule  13e-4(c)  under  the
       Exchange Act (17 CFR 240.13e-4(c))]



Item 1.01.        Entry into a Material Definitive Agreement

Item 5.02.        Compensatory Arrangements of Certain Officers

Establishment of Performance Goals for Annual and Long-Term Incentive Plans

Awards under both the Company's  annual bonus plan and the  long-term  retention
program,  including the long-term  incentive  plan ("LTIP") are issued under the
Company's 2001 Equity Incentive Plan (the "Plan"). The Compensation Committee of
the  Company's   Board  of  Directors  (the   "Committee")  is  responsible  for
establishing  performance  goals for the annual bonus plan and LTIP  performance
periods.

A.       2007 Annual Bonus Plan

         At its meeting on December 6, 2006, the Committee determined amounts
         that may be paid to executive officers and certain senior management
         members of the Company based on the achievement of varying levels of
         operating performance during fiscal year 2007. The awards would be paid
         in cash following completion of the 2007 audited financial statements
         showing the level of operating performance achieved, if the minimum
         threshold level or a higher performance level is achieved.

B.       Long-Term Retention Program

         In order to encourage valuable members of the management team to remain
         with the Company over the next three years, the Committee has adopted a
         long-term retention program that contains two elements: the LTIP and
         the grant of equity.

         1.       2007 LTIP

                  At its meeting on December 6, 2006, the Committee determined
                  amounts that may be paid to executive officers and certain
                  senior management members of the Company in respect of LTIP
                  awards for the three-year 2007-2009 performance period. The
                  Committee established a specified level of operating
                  performance to be achieved during any four consecutive
                  quarters during such performance period that would trigger the
                  payment of the awards. The awards would be paid in cash
                  following confirmation by the Company's independent auditor
                  that the threshold performance level had been achieved.

         2.       Senior Management Stock Options/Stock Grants

                  At its meeting on December 6, 2006, the Committee (a)
                  authorized the reservation of an additional 750,000 shares of
                  common stock for issuance under the Plan and (b) approved the
                  grant under the Plan to members of senior management of LSR of
                  stock options to acquire an aggregate of 480,000 shares of
                  Common Stock, including the following grants to executive
                  officers: options to acquire 100,000 shares to Andrew Baker,
                  Chairman and CEO; options to acquire 100,000 shares to Brian
                  Cass, President and Managing Director; options to acquire
                  50,000 shares to Julian Griffiths, Director of Operations; and
                  options to acquire 100,000 shares to Mark Bibi, General
                  Counsel and Secretary of LSR. The exercise price of such
                  options was $9.95 per share, the average daily high price for
                  the five trading days ending on the date of the December 6
                  Compensation Committee meeting. Such options vest one half on
                  December 31, 2008 and one half on December 31, 2009. The
                  Committee also approved at that meeting the grant of 50,000
                  shares of Common Stock to each of Richard Michaelson, CFO and
                  Mark Bibi, General Counsel and Secretary.


Item 9.01         Financial Statements and Exhibits

         (d)      Exhibits

          10.1 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Andrew Baker.

          10.2 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Brian Cass.

          10.3 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Julian Griffiths.

          10.4 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Mark Bibi.





                                    SIGNATURE



         Pursuant to the requirements of the Securities Exchange Act 1934, Life
Sciences Research, Inc. has duly caused this Report to be signed on its behalf
by the undersigned thereunto duly authorized.

Dated:  December 8, 2006                  LIFE SCIENCES RESEARCH, INC.



                                          By:    /s/   Mark L. Bibi
                                                 ------------------------------
                                          Name:  Mark L. Bibi
                                          Title: Secretary and General Counsel





                                  Exhibit Index


          Exhibit No.


          10.1 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Andrew Baker.

          10.2 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Brian Cass.

          10.3 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Julian Griffiths.

          10.4 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Mark Bibi.