UNITED STATES SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                   Form 8-K/A

                                 Current Report

                       Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934


       Date of Report: (Date of earliest event reported): December 6, 2006


              Life Sciences Research, Inc. ("LSR" or the "Company")
             (Exact name of registrant as specified in its charter)


                                    Maryland
                 (State or other jurisdiction of incorporation)


      0-33505                                      52-2340150
- ---------------------------             ----------------------------------------
(Commission File Number)                 (I.R.S. Employer Identification Number)


Mettlers Road, East Millstone, NJ                    08875
- ------------------------------------       -------------------------------------
(Address of principal executive offices)           (Zip Code)


Registrant's telephone number, including area code:  (732) 649-9961
                                                    ---------------


- ------------------------------------------------------------------
(Former name or former address, if changed since last report)


Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instructions A.2. below):

[   ] Written communications  pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

[   ]  Soliciting  material  pursuant to Rule 14a-12 under the Exchange Act (17
       CFR 240.14a-12)

[   ]  Pre-commencement  communications  pursuant  to Rule  14d-2(b)  under the
       Exchange Act (17 CFR 240.14d-2(b))

[   ]  Pre-commencement  communication  pursuant  to Rule  13e-4(c)  under  the
       Exchange Act (17 CFR 240.13e-4(c))]



EXPLANATORY  NOTE: This Form 8-K/A amends and supplements Items 1.01 and 5.02 of
the Current Report on Form 8-K filed by LSR on December 8, 2006.  This amendment
provides  additional  information  with  respect  to the  performance  goals and
potential costs of the employee incentive plans described below.

Item 1.01.        Entry into a Material Definitive Agreement

Item 5.02.        Compensatory Arrangements of Certain Officers

Establishment of Performance Goals for Annual and Long-Term Incentive Plans

Awards under both the Company's  annual bonus plan and the  long-term  retention
program,  including the long-term incentive plan ("LTIP"),  are issued under the
Company's 2001 Equity Incentive Plan (the "Plan"). The Compensation Committee of
the  Company's   Board  of  Directors  (the   "Committee")  is  responsible  for
establishing  performance  goals for the annual bonus plan and LTIP  performance
periods.

A.   2007 Annual  Bonus Plan At its meeting on December 6, 2006,  the  Committee
     determined  amounts  that may be paid to  executive  officers  and  certain
     senior  management  members  of the  Company  based on the  achievement  of
     varying  levels of  operating  performance  during  fiscal  year 2007.  The
     Committee  established three specific levels of operating margin percentage
     as the thresholds  for payment.  The awards would be paid in cash following
     completion of the 2007 audited  financial  statements  showing the level of
     operating  performance achieved, if the minimum threshold level or a higher
     performance level is achieved.

     The aggregate amount payable to all  participants if the minimum  threshold
     performance level is achieved is approximately $1.5 million;  if the middle
     threshold  performance level is achieved is approximately $3.0 million; and
     if the maximum  threshold level is achieved is approximately  $4.6 million.
     The  potential  ranges of payment under this plan for each of the executive
     officers is as follows:


     Andrew Baker, Chairman and CEO*                   $302,000 - $906,000
     Brian Cass, President and Managing Director*      $302,000 - $906,000
     Richard Michaelson, CFO                           $75,000 - $225,000
     Julian Griffiths, Director of Operations*         $75,500 - $226,500
     Mark Bibi, Secretary and General Counsel          $75,000 - $225,000

     *    Payments to Messrs.  Baker,  Cass and  Griffiths are made in UK pounds
          sterling.  For purposes of estimating these payments in US dollars, an
          exchange rate of (pound)1.00 = $1.83 has been used.

B.       Long-Term Retention Program

     In order to encourage  valuable  members of the  management  team to remain
     with the Company over the next three  years,  the  Committee  has adopted a
     long-term  retention  program that contains two elements:  the LTIP and the
     grant of equity.

     1.   2007 LTIP

          At its meeting on December 6, 2006, the Committee  determined  amounts
          that may be paid to executive  officers and certain senior  management
          members of the  Company in respect of LTIP  awards for the  three-year
          2007-2009  performance  period. The Committee  established a specified
          level of  operating  margin  percentage  to be achieved  over any four
          consecutive quarters during such performance period that would trigger
          the payment of the awards.  This threshold  level of operating  margin
          percentage  is  higher  than the  maximum  level of  operating  margin
          percentage under the 2007 Bonus Plan. The awards would be paid in cash
          following  confirmation by the Company's  independent auditor that the
          threshold performance level had been achieved.

          The aggregate amount payable to all  participants  under the 2007 LTIP
          if the threshold  performance  level is achieved is  approximately  $5
          million.  The  potential  payments  under  this  plan  for each of the
          executive officers is as follows:

          Andrew Baker, Chairman and CEO*                       $1,208,000
          Brian Cass, President and Managing Director*          $1,208,000
          Richard Michaelson, CFO                                 $480,000
          Julian Griffiths, Director of Operations*               $483,000
          Mark Bibi, Secretary and General Counsel                $360,000

          *    Payments  to Messrs.  Baker,  Cass and  Griffiths  are made in UK
               pounds sterling.  For purposes of estimating these payments in US
               dollars, an exchange rate of (pound)1.00 = $1.83 has been used.

         2.    Senior Management Stock Options/Stock Grants

               At its meeting on December 6, 2006,  the Committee (a) authorized
               the  reservation of an additional  750,000 shares of common stock
               for issuance  under the Plan and (b) approved the grant under the
               Plan to members of senior  management  of LSR of stock options to
               acquire an aggregate of 480,000 shares of Common Stock, including
               the following  grants to executive  officers:  options to acquire
               100,000  shares to Andrew  Baker,  Chairman  and CEO;  options to
               acquire  100,000  shares to Brian Cass,  President  and  Managing
               Director;  options to acquire 50,000 shares to Julian  Griffiths,
               Director of Operations;  and options to acquire 100,000 shares to
               Mark Bibi,  General  Counsel and  Secretary  of LSR. The exercise
               price of such options was $9.95 per share, the average daily high
               price  for  the  five  trading  days  ending  on the  date of the
               December 6 Compensation  Committee meeting. Such options vest one
               half on December 31, 2008 and one half on December 31, 2009.  The
               Committee  also  approved  at that  meeting  the  grant of 50,000
               shares of Common  Stock to each of  Richard  Michaelson,  CFO and
               Mark Bibi, General Counsel and Secretary.


Item 9.01      Financial Statements and Exhibits

         (d)      Exhibits

         10.1     Stock Option Agreement, dated as of December 6, 2006, by and
                  between LSR and Andrew Baker. (Incorporated by reference to
                  the Form 8-K filed on December 8, 2006.)

         10.2     Stock Option Agreement,  dated as of December 6, 2006, by and
                  between LSR and Brian Cass.  (Incorporated by reference
                  to the Form 8-K filed on December 8, 2006.)

         10.3     Stock Option  Agreement,  dated as of December 6, 2006, by and
                  between LSR and Julian  Griffiths.  (Incorporated  by
                  reference to the Form 8-K filed on December 8, 2006.)

         10.4     Stock Option Agreement, dated as of December 6, 2006, by and
                  between LSR and Mark Bibi. (Incorporated by reference to the
                  Form 8-K filed on December 8, 2006.)






                                    SIGNATURE



         Pursuant to the requirements of the Securities Exchange Act 1934, Life
Sciences Research, Inc. has duly caused this Report to be signed on its behalf
by the undersigned thereunto duly authorized.

Dated:  December 20, 2006                 LIFE SCIENCES RESEARCH, INC.



                                          By:   /s/   Mark L. Bibi
                                                -----------------------------
                                          Name:  Mark L. Bibi
                                          Title: Secretary and General Counsel






                                  Exhibit Index


          Exhibit No.

          10.1 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Andrew Baker.  (Incorporated  by reference to the
               Form 8-K filed on December 8, 2006.)

          10.2 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Brian Cass.  (Incorporated  by  reference  to the
               Form 8-K filed on December 8, 2006.)

          10.3 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Julian  Griffiths.  (Incorporated by reference to
               the Form 8-K filed on December 8, 2006.)

          10.4 Stock  Option  Agreement,  dated as of December  6, 2006,  by and
               between LSR and Mark Bibi. (Incorporated by reference to the Form
               8-K filed on December 8, 2006.)