EXHIBIT 16.1 July 21, 2006 U. S. Securities and Exchange Commission 450 Fifth Street, NW Washington, DC 20549 Gentlemen: On July 21, 2006, this Firm received a draft copy of a Form 8-K to be filed by SimplaGene USA, Inc. (SEC File #333-100110, CIK #1192323) (Company) reporting an Item 4.01 - Changes in Registrant's Certifying Accountant. We have no disagreements with the statements made in the draft Form 8-K, Item 4.01 disclosures which we read. Yours truly, /s/ S. W. Hatfield, CPA - --------------------------------- S. W. Hatfield, CPA Dallas, Texas