[ENOX LETTERHEAD] October 27, 2008 VIA EDGAR Russell Mancuso, Branch Chief Joseph McCann, Attorney Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Mail Stop 6010 Washington, DC 20549 Re: Enox Biopharma, Inc. Registration Statement on Form SB-2 Filed February 4, 2008 File No. 333-149028 Dear Messrs. Mancuso and McCann: Pursuant to Rule 477 promulgated under the Securities Act of 1933, as amended (the "Securities Act"), Enox Biopharma, Inc. (the "Company") hereby requests the immediate withdrawal of its Registration Statement on Form SB-2 (File No. 333-149028) together with all exhibits thereto (collectively, the "Registration Statement"). The Registration Statement was filed on February 4, 2008 and has not been declared effective. No securities were sold in connection with the offering contemplated in the Registration Statement. In accordance with discussions between the Commission and the Company's counsel, the Company intends to promptly file a new registration statement on Form S-1, which will address the comment received from the Staff on the Registration Statement, in order to re-register the securities covered by the Registration Statement and register additional securities. Such registration statement also will contain updated disclosure. Should you have any questions, please contact the undersigned at 604-603-1806 or David Danovitch or Jaclyn Amsel of Gersten Savage LLP at 212-752-9700. Very truly yours, /s/ Yossef Av-Gay ----------------------------- Prof. Yossef Av-Gay President and CEO