UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 10-K

(Mark One)
[X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
    ACT OF 1934

                  For the fiscal year ended September 30, 2011

[ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
    ACT OF 1934

         For the transition period from ______________to________________

                        Commission file number 000-50331

                            UPSTREAM BIOSCIENCES INC.
             (Exact name of registrant as specified in its charter)

           Nevada                                                98-0371433
(State or other jurisdiction of                               (I.R.S. Employer
 incorporation or organization)                              Identification No.)

50 West Liberty Street, Suite 880, Reno, NV                         89501
  (Address of principal executive offices)                        (Zip Code)

         Registrant's telephone number, including area code 403.537.2516

              Securities registered under Section 12(b) of the Act:

       None                                               N/A
Title of each class                    Name of each exchange on which registered


              Securities registered under Section 12(g) of the Act:

                         Common Stock, $0.001 par value
                                (Title of class)

Indicate by checkmark if the registrant is a well-known seasoned issuer, as
defined in Rule 405 of the Securities Act. Yes [ ] No [X]

Indicate by checkmark if the registrant is not required to file reports pursuant
to Section 13 or 15(d) of the Act. Yes [ ] No [X]

Indicate by checkmark whether the registrant has (1) filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days. Yes [ ] No [X]

Indicate by check mark whether the registrant has submitted electronically and
posted on its corporate Web site, if any, every Interactive Data File required
to be submitted and posted pursuant to Rule 405 of Regulation S-T (ss.232.405 of
this chapter) during the preceding 12 months (or for such shorter period that
the registrant was required to submit and post such files). Yes [ ] No [ ] (Not
currently applicable to the Registrant).

Indicate by checkmark if disclosure of delinquent filers pursuant to Item 405 of
Regulation S-K (ss. 229.405 of this chapter) is not contained herein, and will
not be contained, to the best of registrant's knowledge, in definitive proxy or
information statements incorporated by reference in Part III of this Form 10-K
or any amendment to this Form 10-K. [ ]

Indicate by checkmark whether the registrant is a large accelerated filer, an
accelerated filer, a non-accelerated filer, or a smaller reporting company. See
the definitions of "large accelerated filer," "accelerated filer" and "smaller
reporting company" in Rule 12b-2 of the Exchange Act.

Large  accelerated  filer [ ]                      Accelerated  filer [ ]
Non-accelerated filer [ ]                          Smaller reporting company [X]
(Do not check if a small reporting company)

Indicate by check mark whether the registrant is a shell company (as defined in
Rule 12b-2 of the Act). Yes [ ] No [X]

State the aggregate market value of the voting and non-voting common equity held
by non-affiliates computed by reference to the price at which the common equity
was last sold, or the average bid and asked price of such common equity, as of
the last business day of the registrant's most recently completed second fiscal
quarter: $1,023,362 based on a price of $0.03 per share, being the average bid
and asked price of such common equity as of March 31, 2011.

              APPLICABLE ONLY TO REGISTRANTS INVOLVED IN BANKRUPTCY

                     PROCEEDINGS DURING THE PAST FIVE YEARS:

Indicate by check mark whether the registrant has filed all documents and
reports required to be filed by Section 12, 13 or 15(d) of the Securities
Exchange Act of 1934 subsequent to the distribution of securities under a plan
confirmed by a court. Yes [ ] No [ ]

                   (APPLICABLE ONLY TO CORPORATE REGISTRANTS)

Indicate the number of shares outstanding of each of the registrant's classes of
common stock, as of the latest practicable date. 34,112,065 shares of common
stock as of January 13, 2012.

                       DOCUMENTS INCORPORATED BY REFERENCE

List hereunder the following documents if incorporated by reference and the Part
of the Form 10-K (e.g., Part I, Part II, etc.) into which the document is
incorporated: (1) any annual report to security holders; (2) any proxy or
information statement; and (3) any prospectus filed pursuant to Rule 424(b) or
(c) of the Securities Act of 1933. The listed documents should be clearly
described for identification purposes (e.g., annual report to security holders
for fiscal year ended December 24, 1980). Not Applicable

                                     PART I

FORWARD LOOKING STATEMENTS.

This annual report contains forward-looking statements that involve risks,
uncertainties and assumptions. In some cases, you can identify forward-looking
statements by terminology such as "may", "should", "expect", "plan",
"anticipate", "believe", "estimate", "predict", "potential" or "continue" or the
negative of these terms or other comparable terminology. Examples of
forward-looking statements made in this annual report on Form 10-K include
statements about:

     *    Our business plans,
     *    Our ability to raise additional finances, and
     *    Our future investments and allocation of capital resources.

These statements are only predictions and involve known and unknown risks,
uncertainties and other factors, including:

     *    General economic and business conditions,
     *    Our lack of operating history,
     *    Our financial condition,
     *    Our material weakness in our internal control over financial
          reporting,
     *    Our patents are only a provisional patent, and
     *    The risks in the section of this annual report entitled "Risk
          Factors",

any of which may cause our or our industry's actual results, levels of activity,
performance or achievements to be materially different from any future results,
levels of activity, performance or achievements expressed or implied by these
forward-looking statements.

While these forward-looking statements and any assumptions upon which they are
based are made in good faith and reflect our current judgment regarding the
direction of our business, actual results will almost always vary, sometimes
materially, from any estimates, predictions, projections, assumptions or other
future performance suggested herein. Except as required by applicable law,
including the securities laws of the United States, we do not intend to update
any of the forward-looking statements to conform these statements to actual
results.

The following discussion and analysis should be read in conjunction with the
financial statements and related notes and the other financial information
appearing elsewhere in this annual report. Our financial statements are stated
in United States dollars and are prepared in accordance with United States
Generally Accepted Accounting Principles.

In this report, unless otherwise specified, all dollar amounts are expressed in
United States dollars and all references to "common shares" refer to the common
shares in our capital stock.

As used in this report and unless otherwise indicated, the terms "we", "us" and
"our" refer to Upstream Biosciences Inc.

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ITEM 1. BUSINESS

CORPORATE DEVELOPMENTS

We were incorporated pursuant to the laws of the State of Nevada on March 20,
2002 under the name Integrated Brand Solutions Inc. and on February 6, 2006, we
changed our name to Upstream Biosciences Inc.

We have not generated any revenues from our technologies to date. On August 10,
2009, our company issued a press release announcing that we were actively
seeking licensors or acquirors for our novel anti-parasitic drug discovery
portfolio and cancer diagnostic platform. To that end, our company formed an
independent committee of the board to assess the strategic direction of our
company. During the four months following the issuance of the press release, the
independent board shortlisted a number of potential candidates that may have had
interest in the acquisition of our company's pharmaceutical business as formerly
held by our subsidiary Pacific Pharma Technologies Inc. Our independent
committee contacted such organizations but discussions did not result in any
offers or agreements to acquire such assets.

After several months, our company continued to face challenges in raising funds
due to the continued financial downturn, especially for early-stage life
sciences companies. To this end, and as discussed in our periodic reports, Joel
Bellenson and Dexster Smith, both former directors and officers of our company,
agreed to voluntarily defer their salaries for the 2009 calendar year, or until
such time that our company completed a sizeable financing. TCF Ventures Corp., a
company through which Tim Fernback provided services as chief financial officer
of our company, agreed to defer a portion of the amounts owed to him for
consulting services on the understanding that such amounts would be repaid when
our company obtained sufficient funds. However, a dispute arose as to the terms
of the deferral as discussed under the heading "Item 3 - Legal Proceedings".
Following the continued downturn, low cash reserves, no available financing, and
the commencement of litigation with TCF Ventures, our company was left with two
available options. The first option was to restructure our company, including a
change of its management and board of directors, and the second option was
bankruptcy. As bankruptcy would effectively prevent our shareholders from
realizing any value in our company, the board agreed to restructure our company.
As a result, and following a write-down of the pharmaceutical business operated
by Pacific Pharma, our wholly-owned subsidiary, we entered into the Asset Sale
Agreement to transfer such assets as described below under the heading "Asset
Sale Agreement". Joel Bellenson and Dexster Smith then agreed to enter into
return to treasury agreements and cancel the remaining stock held by them to
treasury for no consideration. The entire board of directors and management
resigned but not before appointing Mike McFarland as sole director and officer
of our company. Following the appointment of the new director, the new board of
directors intends to seek out viable business opportunities in order to maximize
shareholder value.

ASSET SALE AGREEMENT

On December 14, 2009, our subsidiary, Pacific Pharma, a British Columbia
company, entered into and closed an asset sale agreement with JTAT Consulting
Inc., a company wholly-owned by Art Cherkasov. Pursuant to the terms of the
agreement, Pacific Pharma sold all of the assets held by Pacific Pharma to JTAT
Consulting for the payment of $1.00. The assets included the URL domain name
www.pacificpharmatech.com, Pacific Pharma's patents, patent applications, and
inventions, methods, processes and discoveries that may be patentable, Pacific
Pharma's know-how, trade secrets, confidential information, technical
information, data, process technology and plans and drawings, owned, used, or
licensed by Pacific Pharma as licensee or licensor. Our board of directors
decided to proceed with the write-down following our inability to find any
potential acquiror or licensor to purchase the assets and advance the technology
and upon deciding to cease any further research and development of this segment
of our business. The write-down resulted in an impairment charge of $59,010 and
a loss on disposal of $78,570. Our company does not believe that this amount
will result in any future cash expenditures.

RETURN TO TREASURY AGREEMENTS

In connection with the restructuring of our company, and on December 4, 2009, we
entered into a return to treasury agreement with each of Joel Bellenson and
Dexster Smith, both former directors and officers of our company. Pursuant to
the terms of the agreements, each of Mr. Bellenson and Mr. Smith agreed to
return 8,095,470 restricted common shares to the treasury of our company for

                                       3

cancellation without consideration effective December 4, 2009. Following the
share cancellations, each of Joel Bellenson and Dexster Smith held nil shares in
our company.

OPTION TERMINATION AGREEMENTS

On December 14, 2009, Mr. Bellenson and Mr. Smith, both former directors and
officers of our company, entered into Option Termination Agreements with our
company, whereby the 400,000 options held by each person were immediately
cancelled.

RELEASE WITH FORMER DIRECTORS AND MANAGEMENT

On December 14, 2009, our company executed a mutual release with each of Mr.
Bellenson and Mr. Smith, whereby each party agreed to release the other for all
claims each party may have against the other.

SUBSIDIARY

On February 15, 2011, we sold our wholly owned Canadian subsidiary, Upstream
Biosciences, Inc., to an arms length party, for consideration of $1.

OUR BUSINESS

Our business strategy is to generate revenues through licensing our technologies
or collaborating with third parties in the disease susceptibility, biomarkers
identification, and drug response areas of cancer, primarily to companies that
develop and/or market developing diagnostic products.

On June 27, 2008, we re-filed a provisional patent application on genetic
markers that, following successful development and testing, may assist in
determining the susceptibility of patients to liver cancer. These markers may
also be important for determining the susceptibility of patients to other types
of cancer, such as prostate or other cancers. On June 27, 2008, we re-filed a
provisional patent application on an assay for identifying genetic markers that
may predict a patient's response to a drug entitled "In-Vivo Assay, Database and
Software Algorithm for using Liver Enzyme CIS-Regulatory Allelic Binding
Affinities to Profile and Predict a Haplotype's Drug Response". On August 13,
2008, we re-filed the three provisional patents that related to genetic
biomarkers for prostate, ovarian and thyroid cancer susceptibility. On July 22,
2010, we re-filed the five above noted provisional patents along with
provisional patents for "Three-Dimensional Genetic-Variant QSAR Methods" and
"Anti-Parasitic Compounds and Methods for Selection Thereof." On July 21, 2011,
we re-filed the four provisional patents (three susceptibility gene biomarkers
for liver, ovarian and thyroid cancers and the prostate cancer prognosis gene
biomarker. The other 3 provisional patents held by the Company lapsed as these
assets were not getting any interest in discussions with potential collaborators
or licensees/acquirers.

OTHER BUSINESS OPPORTUNITIES

Simultaneously with our genetic diagnostic business, we are seeking new
acquisitions and/or business opportunities with established business entities
for the merger of a business with our company. In certain instances, a business
may wish to become a subsidiary of us or may wish to contribute assets to us
rather than merge. We are not currently in negotiations with any parties to
enter into a business opportunity and there can be no assurance that we will be
able to enter into any agreement. We anticipate that any new acquisition or
business opportunities by our company will require additional financing. There
can be no assurance, however, that we will be able to acquire the financing
necessary to enable us to pursue our plan of operation. If our company requires
additional financing and we are unable to acquire such funds, our business may
fail.

Management of our company believes that there are perceived benefits to being a
reporting company with a class of publicly-traded securities. These are commonly
thought to include: (i) the ability to use registered securities to acquire
assets or businesses; (ii) increased visibility in the financial community;
(iii) the facilitation of borrowing from financial institutions; (iv) improved
trading efficiency; (v) stockholder liquidity; (vi) greater ease in subsequently

                                       4

raising capital; (vii) compensation of key employees through stock options;
(viii) enhanced corporate image; and (ix) a presence in the United States
capital market.

We may seek a business opportunity with entities who have recently commenced
operations, or entities who wish to utilize the public marketplace in order to
raise additional capital in order to expand business development activities, to
develop a new product or service, or for other corporate purposes. We may
acquire assets and establish wholly-owned subsidiaries in various businesses or
acquire existing businesses as subsidiaries.

In implementing a structure for a particular business acquisition or
opportunity, we may become a party to a merger, consolidation, reorganization,
joint venture, or licensing agreement with another corporation or entity. We may
also acquire stock or assets of an existing business.

As of the date hereof, management has not entered into any formal written
agreements for a business combination or opportunity and there is no guarantee
that we will be able to enter into such an agreement.

COMPETITION

The biotechnology industry is highly competitive. Numerous entities in the
United States and elsewhere compete with our efforts to commercialize our
technologies. Our competitors include pharmaceutical, biomedical, biotechnology
and diagnostic companies, academic and research institutions and governmental
and other publicly and privately funded research agencies. We face, and expect
to continue to face, competition from these entities to the extent that they
develop products that have a function similar or identical to the function of
our technologies. We also face, and expect to continue to face, competition from
entities that seek to discover therapeutic and diagnostic products.

Because many of our competitors have substantially greater capital resources and
more experience in research and development, manufacturing and marketing than we
do, we may not succeed in developing our proposed products and bringing them to
market in a cost-effective and timely manner.

We are a development stage company. We have not yet completed the development of
our first product and have no revenue from operations. As a result, we may have
difficulty competing with larger, established biomedical companies and
organizations. Within the global genetic biomarker industry, examples of
publicly traded companies include: Compugen, Ltd., Epigenomics AG, Myriad
Genetics, Inc. and Diagnocure Inc. These companies and organizations have much
greater financial, technical, research, marketing, sales, distribution, service
and other resources than us. Moreover, they may offer broader product lines,
services and have greater name recognition than we do, and may offer discounts
as a competitive tactic.

As we are currently seeking other business opportunities, we compete with other
companies for both the acquisition of prospective properties and businesses and
the financing necessary to develop such properties or businesses.

We conduct our business in an environment that is highly competitive and
unpredictable. In seeking out prospective properties and other businesses, we
have encountered intense competition in all aspects of our proposed business as
we compete directly with other development stage companies as well as
established international companies. Many of our competitors are national or
international companies with far greater resources, capital and access to
information than us. Accordingly, these competitors may be able to spend greater
amounts on the acquisition of prospective properties and on the exploration and
development of such properties or the acquisition of other businesses.

INTELLECTUAL PROPERTY

PATENT APPLICATIONS

Our company has re-filed four original provisional patent applications. Our
company re-files provisional patents with the US Patent and Trademark Office on
an annual basis, prior to completing an initial patent filing as part of our
overall intellectual property strategy. We have identified and filed provisional
patent applications on genetic markers that, following successful development

                                       5

and testing, may assist in determining the susceptibility of patients to liver
cancer, prostate cancer, ovarian cancer, and thyroid cancer.The validity and
breadth of claims in medical technology patents involve complex legal and
factual questions and, therefore, may be highly uncertain. No assurance can be
given that any patents based on pending patent applications or any future patent
applications by us, or any future licensors, will be issued, that the scope of
any patent protection will exclude competitors or provide competitive advantages
to us, that any of the provisional patent applications that have been or may be
issued to us or our licensors will be held valid if subsequently challenged or
that others will not claim rights in or ownership of the provisional patent
applications and other proprietary rights held or licensed by us. Furthermore,
there can be no assurance that others have not developed or will not develop
similar products, duplicate any of our technology or design around any patents
that may be issued to us or our licensors. Since provisional patent applications
in the United States are maintained in secrecy until patents are issued, we also
cannot be certain that others have not or will not file prior applications for
inventions covered by our, and our licensors' pending patent applications, nor
can we be certain that we will not infringe any patents that may be issued to
others on such applications.

We have not conducted freedom of use patent searches and no assurance can be
given that patents do not exist or could not be filed which would have an
adverse affect on our ability to market our technology or maintain our
competitive position with respect to our technology. If our technologies or
subject matter are claimed under other existing United States or foreign patents
or are otherwise protected by third party proprietary rights, we may be subject
to infringement actions. In such event, we may challenge the validity of such
patents or other proprietary rights or we may be required to obtain licenses
from such companies in order to develop, manufacture or market our technology.
There can be no assurances that we will be able to obtain such licenses or that
such licenses, if available, may be obtained on commercially reasonable terms.
Furthermore, the failure to either develop a commercially viable alternative or
obtain such licenses may result in delays in marketing our proposed technology
or the inability to proceed with the development, manufacture or sale of
products requiring such licenses, which may have a material adverse affect on
our business, financial condition and results of operations. If we are required
to defend ourselves against charges of patent infringement or to protect our
proprietary rights against third parties, substantial costs will be incurred
regardless of whether we are successful. Such proceedings are typically
protracted with no certainty of success. An adverse outcome could subject us to
significant liabilities to third parties and force us to curtail or cease our
development and commercialization of our technology.

DOMAIN NAMES

We own the registered internet domain name: www.upstreambio.com but it is
currently inactive. The information contained on our website does not form part
of this annual report.

GENERAL

We also rely on trade secrets and unpatentable know-how that we seek to protect,
in part, by confidentiality agreements. We intend to require all future
employees, consultants, contractors, manufacturers, outside scientific
collaborators and sponsored researchers, directors on our board, technical
review board and other advisors to execute confidentiality agreements upon the
commencement of employment or consulting relationships with us. These agreements
will provide that all confidential information developed or made known to the
individual during the course of the individual's relationship with us is to be
kept confidential and not disclosed to third parties except in specific limited
circumstances. We intend to require signed confidentiality or material transfer
agreements from any company that receives confidential information from our
company. We intend to ensure that, in the case of employees, consultants and
contractors, any agreements that our company enters into with such persons will
generally provide that all inventions conceived by the person while rendering
services to us shall be assigned to us as the exclusive property of our company.
We can offer no assurance, however, that all persons who we seek to sign such
agreements will sign, or if they do, that these agreements will not be breached,
that we will have adequate remedies for any breach, or that our trade secrets or
unpatentable know-how will not otherwise become known or be independently
developed by competitors.

GOVERNMENT REGULATION

The products and technologies that would be developed from our patents will
require regulatory approval by governmental agencies prior to commercialization.
Various federal statutes and regulations also govern or influence the testing,

                                       6

manufacturing, safety, labeling, storage, record keeping, and marketing of
therapeutic products. The process of obtaining these approvals and the
subsequent compliance with applicable statutes and regulations require the
expenditure of substantial time and financial resources.

RESEARCH AND DEVELOPMENT

Our research and development costs primarily consist of research programs
related to the development of drug candidates for the treatment of certain
infectious diseases and cancers. We estimate that we will not have any research
and development cash expenditures for the next twelve months.

Our company incurred no research and developments costs in 2011 and 2010. We
were focused on the restructuring of our company and did not expend funds on
research and development during the past two fiscal years.

EMPLOYEES

We currently have one employee consisting of Michael McFarland, our sole
director and officer. We will hire additional employees when circumstances
warrant.

CUSTOMERS

As we are in the development stage of our business, we do not currently have any
customers of our technologies.

SUPPLIERS

Our company is not reliant upon any suppliers for the research and development
of our technologies.

ITEM 1A. RISK FACTORS

RISKS RELATED TO OUR BUSINESS

WE HAVE HAD NEGATIVE CASH FLOWS FROM OPERATIONS SINCE INCEPTION. WE WILL REQUIRE
SIGNIFICANT ADDITIONAL FINANCING, THE AVAILABILITY OF WHICH CANNOT BE ASSURED,
AND IF OUR COMPANY IS UNABLE TO OBTAIN SUCH FINANCING, OUR BUSINESS MAY FAIL.

To date, we have had negative cash flows from operations and have depended on
sales of our equity securities and debt financing to meet our cash requirements.
Our ability to develop and, if warranted, commercialize our technologies, will
be dependent upon our ability to raise significant additional financing. If we
are unable to obtain such financing, we will not be able to fully develop our
business. Specifically, we will need to raise additional funds to pay our
existing and accrued liabilities, and support our planned growth and carry out
our business plan.

In light of the current financial crises, financing for companies such as ours
is very difficult to obtain. Even if financing is available, it may not be
available on terms that are favorable to us or in sufficient amounts to satisfy
our requirements. If we require, but are unable to obtain, additional financing
in the future, we may be unable to implement our business plan and our growth
strategies, respond to changing business or economic conditions, withstand
adverse operating results and compete effectively. Without additional funds, we
may not be able to pay our employees or contracts to provide services, and these
same employees or service providers may have to either accept accruals or common
shares, or a combination of both, for compensation. More importantly, if we are
unable to raise further financing when required, we may be forced to scale down
our operations and our ability to continue operations may be negatively
affected.

WE HAVE A HISTORY OF LOSSES AND NOMINAL OPERATING RESULTS, WHICH RAISE
SUBSTANTIAL DOUBT ABOUT OUR ABILITY TO CONTINUE AS A GOING CONCERN.

Since inception through the fiscal year ended September 30, 2011, we have
incurred aggregate net losses of $7,108,208. We can offer no assurance that we
will operate profitably or that we will generate positive cash flow in the

                                       7

future. In addition, our operating results in the future may be subject to
significant fluctuations due to many factors not within our control, such as the
level of competition and general economic conditions.

Our company's operations will be subject to all the risks inherent in the
establishment of a developing enterprise and the uncertainties arising from the
absence of a significant operating history. No assurance can be given that we
may be able to operate on a profitable basis.

Due to the nature of our business and the early stage of our development, our
securities must be considered highly speculative. We have not realized a profit
from our operations to date and there is little likelihood that we will realize
any profits in the short or medium term. Any profitability in the future from
our business will be dependent upon the successful commercialization or
licensing of our core technology, which itself is subject to numerous risk
factors as set forth herein or the acquisition of another business.

We expect to continue to incur development costs and operating costs.
Consequently, we expect to incur operating losses and negative cash flows until
our technology gains market acceptance sufficient to generate a sustainable
level of income from the commercialization or licensing of our technology. Our
history of losses and nominal operating results raise substantial doubt about
our ability to continue as a going concern, as described in the explanatory
paragraph in our company's independent registered public accounting firm's audit
report dated January 12, 2012 which is included in our annual report on Form
10-K.

THE WORLDWIDE MACROECONOMIC DOWNTURN MAY REDUCE THE ABILITY OF OUR COMPANY TO
OBTAIN THE FINANCING NECESSARY TO CONTINUE OUR BUSINESS AND MAY REDUCE THE
NUMBER OF VIABLE BUSINESSES THAT WE MAY WISH TO ACQUIRE.

Since 2010, there has been a downturn in general worldwide economic conditions
due to many factors, including the effects of the subprime lending and general
credit market crises, volatile but generally declining energy costs, slower
economic activity, decreased consumer confidence and commodity prices, reduced
corporate profits and capital spending, adverse business conditions, increased
unemployment and liquidity concerns. In addition, these macroeconomic effects,
including the resulting recession in various countries and slowing of the global
economy, will likely result in decreased business opportunities as potential
target companies face increased financial hardship. Tightening credit and
liquidity issues will also result in increased difficulties for our company to
raise capital for our continued operations and to consummate a business
opportunity with a viable business.

WE HAVE IDENTIFIED MATERIAL WEAKNESSES RELATED TO OUR INTERNAL CONTROL OVER
FINANCIAL REPORTING AND CONCLUDED THAT OUR INTERNAL CONTROL OVER FINANCIAL
REPORTING AND DISCLOSURE CONTROLS AND PROCEDURES WERE INEFFECTIVE AS OF
SEPTEMBER 30, 2011. THESE MATERIAL WEAKNESSES REMAIN UNREMEDIED, WHICH COULD
CONTINUE TO IMPACT OUR ABILITY TO REPORT RESULTS OF OPERATIONS AND FINANCIAL
CONDITION ACCURATELY AND IN A TIMELY MANNER.

We have identified a number of material weaknesses in our internal control over
financial reporting. Our management assessed the effectiveness of our internal
control over financial reporting and disclosure controls and procedures as at
September 30, 2011 pursuant to Section 404 of the Sarbanes-Oxley Act of 2002 and
the related SEC rules and concluded that our internal control over financial
reporting and disclosure controls and procedures were ineffective. In connection
with the preparation of our quarterly report for the period ended June 30, 2009,
we determined that an accrual error with respect to the management compensation
of one of our senior officers had been made in our financial statements in prior
periods and we determined that our disclosure controls and procedures were not
effective as at September 30, 2011. We have concluded that four material
weaknesses existed as at September 30, 2011 which are set out in Item 9A under
the heading "Controls and Procedures". Although we intend to remediate such
material weaknesses as set out in Item 9A, we have not yet been able to address
these material weaknesses and they may continue to remain unremedied for some
time, which could adversely impact the accuracy and timeliness of future reports
and filings we make to the SEC and could have a material adverse effect on our
business, results of operations, financial condition and liquidity.

                                       8

WE CURRENTLY HOLD NO PATENTS ON OUR PROPRIETARY TECHNOLOGY AND IF WE ARE NOT
ABLE TO PROTECT OUR PROPRIETARY TECHNOLOGY, OUR COMPANY WILL SUFFER A MATERIAL
ADVERSE EFFECT.

We currently have provisional patent applications filed on our technologies. We
currently rely on the provisional patent applications and trade secrets to
protect our proprietary intellectual property.

While we believe that we have adequately protected our proprietary technology,
and we intend to take all appropriate and reasonable legal measures to protect
it in the future, the use of our technology by a competitor could have a
material adverse effect on our business, financial condition and results of
operations. Our ability to compete successfully and achieve future revenue
growth will depend, in part, on our ability to protect our proprietary
technology and operate without infringing upon the rights of others. We may not
be able to successfully protect our proprietary technology, and our proprietary
technology may otherwise become known or similar technology may be independently
developed by competitors. Competitors may discover novel uses, develop similar
or more marketable technologies or offer services similar to our company at
lower prices. We cannot predict whether our technologies and services will
compete successfully with the technologies and services of existing or emerging
competitors.

WE MAY LOSE OUR COMPETITIVENESS IF WE ARE NOT ABLE TO PROTECT OUR PROPRIETARY
TECHNOLOGY AND INTELLECTUAL PROPERTY RIGHTS AGAINST INFRINGEMENT, AND ANY
RELATED LITIGATION MAY BE TIME-CONSUMING AND COSTLY.

Our success and ability to compete depends to a significant degree on our
proprietary technology. If any of our competitors copy or otherwise gain access
to our proprietary technology or develop similar technologies independently, we
may not be able to compete as effectively. The measures we have implemented to
protect our proprietary technology and other intellectual property rights are
currently based upon a combination of provisional patent applications,
technology licenses and trade secrets. This, however, may not be adequate to
prevent the unauthorized use of our proprietary technology and our other
intellectual property rights. Further, the laws of foreign countries may provide
inadequate protection of such intellectual property rights. We may need to bring
legal claims to enforce or protect such intellectual property rights. Any
litigation, whether successful or unsuccessful, may result in substantial costs
and a diversion of our company's resources. In addition, notwithstanding our
rights to our intellectual property, other persons may bring claims against us
alleging that we have infringed on their intellectual property rights or claims
that our intellectual property rights are not valid. Any claims against us, with
or without merit, could be time consuming and costly to defend or litigate,
divert our attention and resources, result in the loss of goodwill associated
with our business or require us to make changes to our technology.

IF OUR PROVISIONAL PATENT APPLICATIONS AND PROPRIETARY RIGHTS DO NOT PROVIDE
SUBSTANTIAL PROTECTION, THEN OUR BUSINESS AND COMPETITIVE POSITION WILL SUFFER.

Our success depends in large part on our, and any of our potential
collaborators, ability to develop, commercialize and protect our proprietary
technology. However, patents may not be granted on any of our provisional or
future patent applications. Also, the scope of any future patent may not be
sufficiently broad to offer meaningful protection. In addition, any patents
granted to us in the future may be successfully challenged, invalidated or
circumvented so that such patent rights may not create an effective competitive
barrier.

OUR COMPANY MAY BECOME SUBJECT TO INTELLECTUAL PROPERTY LITIGATION WHICH MAY
HARM OUR BUSINESS.

Our success depends in part on our ability to develop commercially viable
products without infringing the proprietary rights of others. Although we have
not been subject to any filed infringement claims, other patents could exist or
could be filed which may prohibit or limit our ability to market our products or
maintain a competitive position. In the event of an intellectual property
dispute, we may be forced to litigate. Intellectual property litigation may
divert management's attention from developing our technology and may force us to
incur substantial costs regardless of whether we are successful. An adverse
outcome could subject us to significant liabilities to third parties, and force
us to curtail or cease the development and commercialization of our technology.

WE HAVE NOT GENERATED ANY REVENUES FROM OPERATIONS AND IF WE ARE UNABLE TO
DEVELOP MARKET SHARE AND GENERATE SIGNIFICANT REVENUES FROM THE
COMMERCIALIZATION OR LICENSING OF OUR TECHNOLOGY, THEN OUR BUSINESS MAY FAIL.

We operate in a highly competitive industry and our failure to compete
effectively and generate income through the licensing of our technology may
adversely affect our ability to generate revenue. There can be no assurance that
our new or existing technologies will gain market acceptance. Management is
aware of similar technologies that our technology, when developed to a stage of

                                       9

commercialization, will compete directly against. Many of our competitors have
greater financial, technical, sales and marketing resources, better name
recognition and a larger customer base than ours. In addition, many of our large
competitors may offer customers a broader or superior range of services and
technologies. Some of our competitors may conduct more extensive promotional
activities and offer lower licensing costs to customers than we do, which could
allow them to gain greater market share or prevent us from establishing and
increasing our market share. Increased competition in the genetic biomarker
industry and the drug development industry may result in significant price
competition, reduced profit margins or loss of market share, any of which may
have a material adverse effect on our ability to generate revenues and
successfully operate our business. Our competitors may develop technologies
superior to those that our company is currently developing. In the future, we
may need to decrease our prices if our competitors lower their prices. Our
competitors may be able to respond more quickly to new or changing
opportunities, technologies and customer requirements. Such competition will
potentially affect our chances of achieving profitability, and ultimately affect
our ability to continue as a going concern.

RAPID TECHNOLOGICAL CHANGES IN OUR INDUSTRY MAY RENDER OUR TECHNOLOGY
NON-COMPETITIVE OR OBSOLETE AND CONSEQUENTLY AFFECT OUR ABILITY TO GENERATE
FUTURE REVENUES.

The genetic biomarker industry is characterized by rapidly changing technology,
evolving industry standards and varying customer demand. We believe that our
success will depend on our ability to generate income through the licensing of
our technology. We can make no assurance that our technology will not become
obsolete due to the introduction of alternative technologies. If we are unable
to continue to develop and introduce new genetic biomarkers, new biotechnology
drugs and drug candidates to meet technological changes and changes in market
demands, our business and operating results, including our ability to generate
revenues, may be adversely affected.

IF WE DO NOT KEEP PACE WITH OUR COMPETITORS, TECHNOLOGICAL ADVANCEMENTS AND
MARKET CHANGES, OUR TECHNOLOGY MAY BECOME OBSOLETE AND OUR BUSINESS MAY SUFFER.

The market for our technology is very competitive, is subject to rapid
technological changes and varies for different individual products. We believe
that there are potentially many competitive approaches being pursued that
compete with our technology, including some by private companies for which
information is difficult to obtain.

Many of our competitors have significantly greater resources and have developed
products and processes that directly compete with our technology. Our
competitors may develop, or may in the future develop, new technologies that
directly compete with our technology or even render our technology obsolete. Our
technology is designed to develop diagnostic products as well as treatments for
certain diseases. Even if we are able to demonstrate improved or equivalent
results from our technology, researchers and practitioners may not use our
technology and we may suffer a competitive disadvantage. Finally, to the extent
that others develop new technologies that address the targeted application for
our current technology, our business will suffer.

OUR BUSINESS IS SUBJECT TO COMPREHENSIVE GOVERNMENT REGULATION AND ANY CHANGE IN
SUCH REGULATION MAY HAVE A MATERIAL ADVERSE EFFECT ON OUR COMPANY.

There is no assurance that the laws, regulations, policies or current
administrative practices of any government body, organization or regulatory
agency in the United States, Canada or any other jurisdiction, will not be
changed, applied or interpreted in a manner which will fundamentally alter the
ability of our company to carry on our business. The actions, policies or
regulations, or changes thereto, of any government body or regulatory agency, or
other special interest groups, may have a detrimental effect on our company. Any
or all of these situations may have a negative impact on our operations.

                                       10

RISKS RELATED TO OUR COMMON STOCK

A DECLINE IN THE PRICE OF OUR COMMON STOCK COULD AFFECT OUR ABILITY TO RAISE
FURTHER WORKING CAPITAL AND ADVERSELY IMPACT OUR ABILITY TO CONTINUE OPERATIONS.

A prolonged decline in the price of our common stock could result in a reduction
in the liquidity of our common stock and a reduction in our ability to raise
capital. Because a significant portion of our operations has been and will be
financed through the sale of equity securities, a decline in the price of our
common stock could be especially detrimental to our liquidity and our
operations. Such reductions may force us to reallocate funds from other planned
uses and may have a significant negative effect on our business plans and
operations, including our ability to develop new products and continue our
current operations. If our stock price declines, we can offer no assurance that
we will be able to raise additional capital or generate funds from operations
sufficient to meet our obligations. If we are unable to raise sufficient capital
in the future, we may not be able to have the resources to continue our normal
operations.

The market price for our common stock may also be affected by our ability to
meet or exceed expectations of analysts or investors. Any failure to meet these
expectations, even if minor, may have a material adverse effect on the market
price of our common stock.

IF WE ISSUE ADDITIONAL SHARES IN THE FUTURE, IT WILL RESULT IN THE DILUTION OF
OUR EXISTING SHAREHOLDERS.

Our certificate of incorporation authorizes the issuance of up to 750,000,000
shares of common stock with a $0.001 par value and 100,000,000 preferred shares
with a par value of $0.001, of which 34,112,065 common shares were issued and
outstanding as of September 30, 2011. Our board of directors may fix and
determine the designations, rights, preferences or other variations of each
class or series within each class. Our board of directors may choose to issue
some or all of such shares to acquire one or more businesses or to provide
additional financing in the future. The issuance of any such shares will result
in a reduction of the book value and market price of the outstanding shares of
our common stock. If we issue any such additional shares, such issuance will
cause a reduction in the proportionate ownership and voting power of all current
shareholders. Further, such issuance may result in a change of control of our
company.

TRADING OF OUR STOCK MAY BE RESTRICTED BY THE SECURITIES EXCHANGE COMMISSION'S
PENNY STOCK REGULATIONS, WHICH MAY LIMIT A STOCKHOLDER'S ABILITY TO BUY AND SELL
OUR STOCK.

The Securities and Exchange Commission has adopted regulations which generally
define "penny stock" to be any equity security that has a market price (as
defined) less than $5.00 per share or an exercise price of less than $5.00 per
share, subject to certain exceptions. Our securities are covered by the penny
stock rules, which impose additional sales practice requirements on
broker-dealers who sell to persons other than established customers and
"accredited investors". The term "accredited investor" refers generally to
institutions with assets in excess of $5,000,000 or individuals with a net worth
in excess of $1,000,000 or annual income exceeding $200,000 or $300,000 jointly
with their spouse. The penny stock rules require a broker-dealer, prior to a
transaction in a penny stock not otherwise exempt from the rules, to deliver a
standardized risk disclosure document in a form prepared by the Securities and
Exchange Commission, which provides information about penny stocks and the
nature and level of risks in the penny stock market. The broker-dealer also must
provide the customer with current bid and offer quotations for the penny stock,
the compensation of the broker-dealer and its salesperson in the transaction and
monthly account statements showing the market value of each penny stock held in
the customer's account. The bid and offer quotations, and the broker-dealer and
salesperson compensation information, must be given to the customer orally or in
writing prior to effecting the transaction and must be given to the customer in
writing before or with the customer's confirmation. In addition, the penny stock
rules require that prior to a transaction in a penny stock not otherwise exempt
from these rules, the broker-dealer must make a special written determination
that the penny stock is a suitable investment for the purchaser and receive the
purchaser's written agreement to the transaction. These disclosure requirements
may have the effect of reducing the level of trading activity in the secondary
market for the stock that is subject to these penny stock rules. Consequently,
these penny stock rules may affect the ability of broker-dealers to trade our
securities. We believe that the penny stock rules discourage investor interest
in and limit the marketability of our common stock.

FINRA'S SALES PRACTICE REQUIREMENTS MAY ALSO LIMIT A STOCKHOLDER'S ABILITY TO
BUY AND SELL OUR STOCK.

In addition to the "penny stock" rules promulgated by the Securities and
Exchange Commission (see above for a discussion of penny stock rules), FINRA
rules require that in recommending an investment to a customer, a broker-dealer
must have reasonable grounds for believing that the investment is suitable for
that customer. Prior to recommending speculative low priced securities to their

                                       11

non-institutional customers, broker-dealers must make reasonable efforts to
obtain information about the customer's financial status, tax status, investment
objectives and other information. Under interpretations of these rules, FINRA
believes that there is a high probability that speculative low priced securities
will not be suitable for at least some customers. FINRA requirements make it
more difficult for broker-dealers to recommend that their customers buy our
common stock, which may limit your ability to buy and sell our stock and have an
adverse effect on the market for our shares.

OUR COMMON STOCK IS ILLIQUID AND THE PRICE OF OUR COMMON STOCK MAY BE NEGATIVELY
IMPACTED BY FACTORS WHICH ARE UNRELATED TO OUR OPERATIONS.

Our common stock is currently quoted on the OTC QB. Trading of our stock through
the OTC QB is frequently thin and highly volatile. There is no assurance that a
sufficient market will develop in the stock, in which case it could be difficult
for shareholders to sell their stock. The market price of our common stock could
fluctuate substantially due to a variety of factors, including market perception
of our ability to achieve our planned growth, quarterly operating results of our
competitors, trading volume in our common stock, changes in general conditions
in the economy and the financial markets or other developments affecting our
competitors or us. In addition, the stock market is subject to extreme price and
volume fluctuations. This volatility has had a significant effect on the market
price of securities issued by many companies for reasons unrelated to their
operating performance and could have the same effect on our common stock.

ITEM 2. PROPERTIES

EXECUTIVE OFFICES

Subsequent to the fiscal year end, our office location moved to 50 West Liberty
Street, Suite 880, Reno, NV, 88501. For the past fiscal year and effective
December 14, 2009, our principal offices were located at 71130, 198 - 8060
Silver Spring Blvd., Calgary, Alberta, Canada. Our sole director and officer
provided this space to us free of charge. We do not own any real property. We
believe this office will be adequate for the near future.

ITEM 3. LEGAL PROCEEDINGS

Other than as set forth below, we know of no material, active, or pending legal
proceeding against our company, nor are we involved as a plaintiff in any
material proceeding or pending litigation where such claim or action involves
damages for more than 10% of our current assets as of January 13, 2012.
Additionally, there were no proceedings in which any of our company's directors,
officers, or affiliates, or any registered or beneficial shareholders holding
more than 5% of our voting securities, is an adverse party or has a material
interest adverse to our company's interest as of January 13, 2012.

On September 1, 2009, TCF Ventures filed a Writ of Summons and Statement of
Claim against our company. The Statement of Claim alleged that our company
notified TCF Ventures that it would be reducing amounts payable to TCF Ventures
by 33% and that our company would eventually repay the salary owed when it had
sufficient funds. TCF Ventures accepted the deferral of salary on the
understanding that the deferral was temporary and that it would be repaid as
soon as possible. The Statement of Claim further alleged that on or about
January 2009, our company notified TCF Ventures that our company would be
deferring the salary by 50%. In response, on or about February 3, 2009, the
Statement of Claim alleges that TCF Ventures delivered a written notice to our
company advising that our company was in material breach of the agreement for
failing to pay the salary. TCF Ventures claimed judgment against our company for
$68,750 plus GST for outstanding salary under the agreement and $150,000 for
severance.

On September 22, 2009, our company filed a Statement of Defence against TCF
Ventures, whereby our company denied the allegations made against our company
and counter claimed against TCF Ventures, which counterclaim included the
following: (a) causing our company to pay GST on amounts payable to TCF
Ventures, even though the agreement did not provide for the payment of GST to
TCF Ventures; (b) failure to cause our company to deduct GST from amounts
payable to TCF Ventures and to remit such payments to the required government
authority; and (c) during the term of the agreement, Mr. Fernback caused our
company to overpay on salary payments by applying a rate of exchange between the
Canadian and US dollars that was more favourable to TCF Ventures than existing

                                       12

market rates. Our company took the position that such breaches constituted
repudiation of the agreement with TCF Ventures such that our company was
entitled to treat the agreement at an end and that TCF Ventures has no cause of
action against our company for the severance. Our company further claimed that
our company was entitled to repayment of the GST paid to TCF Ventures and the
amount paid in excess of the market exchange rates, and therefore claimed a
right of set-off for such amounts against any amount held to be owing to TCF
Ventures.

On December 14, 2009, TCF Ventures and our company signed a mutual release
whereby, in consideration for the payment of $50,000 from our company to TCF
Ventures, both parties agreed to release each other from all claims or
liabilities for any allegations pled in the Statement of Claim and the Statement
of Defence.

ITEM 4. (REMOVED AND RESERVED)

                                    PART II

ITEM 5. MARKET FOR REGISTRANT'S COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND
        ISSUER PURCHASES OF EQUITY SECURITIES

MARKET FOR SECURITIES

Our stock is listed for quotation on the OTC QB under the trading symbol "UPBS".
Our common shares initially began trading on the OTC Bulletin Board on September
1, 2004 under the trading symbol "IBSO.OB". The following table sets forth, for
the periods indicated, the high and low closing prices for each quarter within
the last two fiscal years ended September 30, 2011 as reported by the quotation
service operated by the OTC QB. All quotations for the OTC QB reflect
inter-dealer prices, without retail mark-up, mark-down or commission and may not
necessarily represent actual transactions.

    Quarter Ended                        High                   Low
    -------------                        ----                   ---
    September 30, 2011                   $0.02                  $0.00
    June 30, 2011                        $0.04                  $0.01
    March 31, 2011                       $0.04                  $0.01
    December 31, 2010                    $0.06                  $0.01
    September 30, 2010                   $0.02                  $0.01
    June 30, 2010                        $0.02                  $0.01
    March 31, 2010                       $0.02                  $0.01
    December 31, 2009                    $0.03                  $0.02

On January 12, 2012, the closing price for the common stock as reported by the
quotation service operated by the OTC QB was $0.01.

Nevada Agency and Transfer Company is the registrar and transfer agent for our
common shares. Their address is 50 West Liberty, Suite 800 Reno, Nevada, 89501
Telephone: 775.322.0626, Facsimile: 775.322.5623.

HOLDERS OF OUR COMMON STOCK

As of January 13, 2012 there were 10 registered holders of record of our common
stock. As of such date, 34,112,065 common shares were issued and outstanding.

DIVIDEND POLICY

We have not declared or paid any cash dividends since inception. Although there
are no restrictions that limit our ability to pay dividends on our common
shares, we intend to retain future earnings, if any, for use in the operation
and expansion of our business and do not intend to pay any cash dividends in the
foreseeable future.

                                       13

EQUITY COMPENSATION PLAN INFORMATION

On March 16, 2007, our board of directors approved the 2007 Stock Option Plan.
Under the terms of the 2007 Stock Option Plan, options to purchase up to
5,000,000 shares of our common stock may be granted to our officers, directors,
employees and permitted consultants of our company.

The following table sets forth certain information concerning all equity
compensation plans previously approved by stockholders and all previous equity
compensation plans not previously approved by stockholders, as of the most
recently completed fiscal year.

EQUITY COMPENSATION PLAN INFORMATION AS AT SEPTEMBER 30, 2011



                                                                                                     Number of Securities
                                                                                                   Remaining Available for
                                 Number of Securities to be                                         Future Issuance Under
                                  Issued Upon Exercise of         Weighted-Average Exercise       Equity Compensation Plans
                                   Outstanding Options,        Price of Outstanding Options,  (excluding securities reflected
   Plan Category                   Warrants and Rights             Warrants and Rights               in the first column)
   -------------                   -------------------             -------------------               --------------------
                                                                                        
Equity Compensation Plans to               N/A                             N/A                                N/A
be Approved by Security
Holders

Equity Compensation Plans Not           800,000                           $1.02                           4,200,000
Approved by Security Holders

Total                                   800,000                           $1.02                           4,200,000


RECENT SALES OF UNREGISTERED SECURITIES

The following sets forth certain information concerning securities which were
sold or issued by us during the last fiscal year ended September 30, 2011
without the registration of these securities under the Securities Act of 1933 in
reliance on exemptions from such registration requirements.

None.

ITEM 6. SELECTED FINANCIAL DATA

Not Applicable.

ITEM 7. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATION

The following discussion should be read in conjunction with our audited
consolidated financial statements and the related notes that appear elsewhere in
this annual report. The following discussion contains forward-looking statements
that reflect our plans, estimates and beliefs. Our actual results could differ
materially from those discussed in the forward looking statements. Factors that
could cause or contribute to such differences include those discussed below and
elsewhere in this annual report.

Our audited consolidated financial statements are stated in United States
dollars and are prepared in accordance with United States generally accepted
accounting principles.

                                       14

PLAN OF OPERATIONS AND CASH REQUIREMENTS OVER THE NEXT 12 MONTHS

Without adequate funding, it is management's intention to halt current research
and development efforts associated with our biomarker program and wait until
sufficient financial resources exist before spending additional and significant
funds for the commercialization of our biomarker program. However, we will
continue to evaluate and determine the most cost effective use of available
funds for all future research and development programs, including diagnostic
biomarkers, biomarkers for a drug response assay and drug development efforts.

There is no assurance that our research and development programs will produce
commercially viable products or treatments, and a great deal of additional
research and development will be required before a final evaluation of the
economic feasibility of our technologies can be determined.

We are also currently seeking new acquisitions and/or business opportunities
with established business entities for the merger of a target business with our
company including businesses not having a resource focus. In certain instances,
a target business may wish to become a subsidiary of us or may wish to
contribute assets to us rather than merge. There can be no assurance that we
will be able to enter into any agreements. We anticipate that any new
acquisition or business opportunities by our company will require additional
financing. There can be no assurance, however, that we will be able to acquire
the financing necessary to enable us to pursue our plan of operation. If our
company requires additional financing and we are unable to acquire such funds,
our business may fail.

ANTICIPATED CASH REQUIREMENTS

Over the next 12 months, we have estimated our minimum cash requirements to be
as follows:

               ESTIMATED EXPENSES FOR THE NEXT TWELVE MONTH PERIOD

            Cash Operating Expenses
              Employee and consultant compensation          $ 15,000
              Professional fees                             $ 25,000
              General and administrative expenses           $ 30,000
              Corporate communications                      $ 10,000
                                                            --------

            Total                                           $ 80,000
                                                            ========

For the 12 months ended September 30, 2011, we recorded a net operating loss of
$57,658 and have an accumulated deficit of $7,205,908 since inception. As at
September 30, 2011, we had a working capital deficit of $58,515 and for the next
12 months, management estimates minimum cash requirements of $80,000 to fund
on-going operations and planned research and development programs. Accordingly,
we do not have sufficient funds to meet our plan of operation over the next 12
months and will need to obtain further financing through issuance of shares,
debentures or convertible debentures. We will also endeavor to access available
funding from research and development grants or loans from various public and
private research granting agencies. Moreover, all cash operating expenses will
be carefully monitored to ensure we can meet our obligations as they come due.

Due to the current financial crisis, there can be no assurance that additional
financing will be available when needed or, if available, on commercially
reasonable terms. If we are not able to obtain additional financing on a timely
basis, we may not be able to meet our obligations as they come due and may be
forced to scale down or perhaps even cease business operations.

LIQUIDITY AND CAPITAL RESOURCES

Our financial position as at September 30, 2011 and September 30, 2010 and the
changes for the years then ended are as follows:

                                       15

WORKING CAPITAL

                                                   As at               As at
                                               September 30,       September 30,
                                                   2011                2010
                                                ----------          ----------
Current Assets                                  $   12,998          $   41,411
Current Liabilities                             $   71,513          $  185,882
Working Capital (Deficiency)                    $  (58,515)         $ (144,471)

Working capital deficiency has decreased by $85,956 from the year ended
September 30, 2010 to September 30, 2011 as a result of our company being able
to sell our subsidiary.

CASH FLOWS

                                                   As at               As at
                                               September 30,       September 30,
                                                   2011                2010
                                                ----------          ----------
Net cash (used in) Operating Activities         $ (52,996)          $(192,410)
Net cash from (used in) Investing Activities    $       1           $  30,235
Net cash provided by Financing Activities       $  35,000           $      --
Effect of exchange rate changes                 $    (555)          $ (16,007)
Increase (Decrease) in Cash during the Year     $ (18,550)          $(178,182)
Cash, Beginning of Year                         $  31,152           $ 209,334
Cash, End of Year                               $  12,602           $  31,152

During the years ended September 30, 2011 and 2010:

     (i)  Our net cash used in operating activities decreased by $139,414
          primarily due to our company focusing ( on reducing expenses and
          conserving our available cash.

     (ii) Our net cash provided by investing activities of $1 in 2011 related to
          the sale of our subsidiary. Our net cash provided by investing
          activities of $30,235 in 2010 resulted from converting $31,765 of
          restricted cash to cash, offset by the purchase of equipment for
          $1,530.

     (iii) Our net cash from financing activities was $35,000 in 2011 and $nil
          in 2010.

RESULTS OF OPERATIONS FOR YEAR ENDING SEPTEMBER 30, 2011

The following summary should be read in conjunction with our audited financial
statements for the years ended September 30, 2011 and 2010 included herein.

                                       16

                                               Year Ended           Year Ended
                                              September 30,        September 30,
                                                  2011                 2010
                                               ----------           ----------

Revenue                                        $       --           $       --
                                               ----------           ----------

Expenses
  Management and consulting fees                       --               72,245
  Amortization                                        175                  192
  License fees and royalties                        9,375               24,016
  Loss (gain) of foreign exchange                      --                5,533
  Professional fees                                31,812               76,196
  General and administration                       13,761               37,402
  Interest (income) expense - net                   2,535               32,247
                                               ----------           ----------

Total expenses                                 $   57,658           $  247,831
                                               ==========           ==========

Compensation shares                            $       --           $   25,000
Loss on sale of intellectual property                  --               78,570
Sale of subsidiary                               (126,515)                  --
                                               ----------           ----------
Income (loss) before income taxes                 (68,857)             351,401
Deferred income tax benefit                            --               27,857
                                               ----------           ----------

Net Income (Loss)                              $   68,857           $ (323,544)
                                               ==========           ==========

REVENUE

We are a development stage company and have not generated any revenues from our
technologies since inception. We anticipate significant additional time and
financing will be required before our technologies are developed to a marketable
state.

EXPENSES

Our operating expenses for the year ended September 30, 2011 were $57,658
compared to $247,831 in 2010. This net decrease of $190,173 was primarily due to
the following:

     *    $72,245 increase in management and consulting fees due to us
          renegotiating its management compensation structure
     *    $23,641 decrease in general and administration due to a cash
          conservation strategy adopted by our management during the fiscal
          year.
     *    $14,641 decrease in license fees and royalties expenses due to our
          selling of our subsidiary.
     *    $29,712 decrease in interest expense.

GOING CONCERN

The audited financial statements accompanying this report have been prepared on
a going concern basis, which implies that our company will continue to realize
its assets and discharge its liabilities and commitments in the normal course of
business. Our company has not generated revenues since inception, has never paid
any dividends and is unlikely to pay dividends or generate earnings in the
immediate or foreseeable future. The continuation of our company as a going
concern is dependent upon: (i) the continued financial support from our
shareholders; (ii) the ability of our company to continue raising necessary
equity financing to achieve its operating objectives; and (iii) the eventual
attainment of profitable operations.

                                       17

Our independent auditors included an explanatory paragraph in their annual
report on our financial statements for the year ended September 30, 2011
regarding concerns about our ability to continue as a going concern. In
addition, our financial statements contain further note disclosures in this
regard. The continuation of our business plan is dependent upon our ability to
continue raising sufficient new capital from equity or debt markets in order to
fund our on-going operating losses and oil and gas acquisition and exploration
activities. The issuance of additional equity securities could result in a
significant dilution in the equity interests of our current stockholders.

APPLICATION OF CRITICAL ACCOUNTING POLICIES

The preparation of financial statements in conformity with United States
generally accepted accounting principles requires management to make estimates
and assumptions that affect the amounts reported in the financial statements and
accompanying disclosures of our company. Although these estimates are based on
management's knowledge of current events and actions that our company may
undertake in the future, actual results may differ from such estimates.

BASIS OF PRESENTATION AND CONSOLIDATION
These consolidated financial statements and related notes are presented in
accordance with United States generally accepted accounting principles ("US
GAAP") and are expressed in US dollars. The Company is in the development stage
and has not realized significant revenues from its business plan to date. These
financial statements include the accounts of the Company and its wholly-owned
Canadian subsidiaries, Upstream Biosciences, Inc. ("Upstream Canada") up to the
date of its sale on February 15, 2011 (Note 4) and Pacific Pharma Technologies
Inc. ("PPT"). All inter-company transactions and account balances have been
eliminated on consolidation.

The Company acquired Upstream Canada on February 24, 2006. This transaction was
accounted for as a recapitalization transaction, similar to a reverse
acquisition accounting, with Upstream Canada being treated as the accounting
parent (legal subsidiary) and the Company being treated as the accounting
subsidiary (legal parent). Accordingly, the consolidated results of operations
of the Company include those of Upstream Canada for the period from its
inception on June 14, 2004 to the date of its sale on February 15, 2011 and
those of the Company since the date of the reverse acquisition, February 24,
2006.

EQUIPMENT
Equipment is valued at cost less accumulated amortization. Amortization is
recorded using the straight-line method over four years and maintenance and
repairs are expensed as incurred.

USE OF ESTIMATES AND ASSUMPTIONS
The preparation of financial statements in conformity with US GAAP requires the
Company to make estimates and assumptions that affect the reported amounts of
assets and liabilities and disclosure of contingent assets and liabilities at
the date of the financial statements and the reported amounts of revenue and
expenses during the reporting period. The Company bases its estimates and
assumptions on current facts, historical experience and various other factors
that it believes to be reasonable under the circumstances, the results of which
form the basis for making judgments about the carrying values of assets and
liabilities and the accrual of costs and expenses that are readily apparent from
other sources. The actual results experienced by the Company may differ
materially from the Company's estimates. To the extent there are material
differences, future results may be affected. Estimates used in preparing these
financial statements include the fair value of share-based payments, deferred
income taxes, financial instruments and assumptions relating to going concern.

SHARE-BASED COMPENSATION
The Company accounts for share-based compensation using the fair value method
and related compensation expense is recognized over the period of benefit when
the service is rendered.

FINANCIAL INSTRUMENTS
The Company's financial instruments consist of cash, other receivables, accounts
payable and amounts due to related parties. The carrying amounts of these
financial instruments at September 30, 2011 and 2010 approximate their fair
values due to their short term nature.

                                       18

FOREIGN CURRENCY TRANSACTIONS AND TRANSLATION
The functional currency of the Company is the Canadian dollar. The financial
statements are translated into United States dollars using period-end rates of
exchange for assets and liabilities, and period average rates of exchange for
revenues and expenses. Foreign currency gains (losses) arising from translation
are included in other comprehensive income (loss) which is disclosed as a
separate component of shareholders' deficit. The Company has not entered into
any derivative instruments to offset the impact of foreign currency
fluctuations.

RESEARCH AND DEVELOPMENT
These costs are expensed when incurred and consist primarily of direct material
and personnel costs, contract services and indirect costs. The Company has
received government assistance in the past and may receive same in the future
regarding its research and development activities. When the work is performed
that qualifies for such grants, the related assistance amount is credited to
research and development expense.

INCOME TAXES
The Company uses the asset and liability method of accounting for income taxes.
Under this method, deferred tax assets and liabilities are determined based on
temporary differences between the financial statements and the tax basis of
assets and liabilities, and net operating loss carry forwards based on using
enacted tax rates in effect for the year in which the differences are expected
to reverse. The effect of a change in tax rates on deferred tax assets and
liabilities is recognized in income in the year that includes the enactment
date. Deferred tax assets are only recognized to the extent that it is
considered more likely than not that the assets will be realized. At September
30, 2011 and 2010, a valuation allowance for the full amount of the deferred tax
assets was recorded.

EARNINGS (LOSS) PER SHARE
Basic earnings (loss) per share is computed by dividing the net loss by the
weighted average number of outstanding common shares during the year. Diluted
loss per share gives effect to all potentially dilutive common shares
outstanding during the year, including convertible debt, stock options and share
purchase warrants, using the treasury stock method. The computation of diluted
loss per share does not assume conversion, exercise or contingent exercise of
securities that would have an anti-dilutive effect on loss per share.

RECENT ACCOUNTING PRONOUNCEMENTS

We do not believe that any recently issued, but not yet effective accounting
standards if currently adopted, will have a material effect on our financial
statements.

OFF-BALANCE SHEET ARRANGEMENTS

We have no significant off-balance sheet arrangements that have or are
reasonably likely to have a current or future effect on our financial condition,
changes in financial position, revenues and expenses, results of operations,
liquidity, capital expenditures or capital resources that are material to
stockholders.

                                       19

ITEM 8. FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

             REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Stockholders and Board of Directors of Upstream Biosciences, Inc.

We have  audited  the  accompanying  consolidated  balance  sheets  of  Upstream
Biosciences,  Inc. (a  development  stage  company) as of September 30, 2011 and
2010 and the  related  consolidated  statements  of  operations,  cash flows and
stockholders' deficit for the years then ended and the period from June 14, 2004
(inception)  to  September  30,  2011.   These  financial   statements  are  the
responsibility of the Company's management.  Our responsibility is to express an
opinion on these financial statements based on our audits.

We conducted our audits in accordance  with the standards of the Public  Company
Accounting Oversight Board (United States). Those standards require that we plan
and  perform  an audit to obtain  reasonable  assurance  whether  the  financial
statements  are free of material  misstatement.  The Company is not  required to
have,  nor were we engaged to perform,  an audit of its  internal  control  over
financial reporting.  Our audits included consideration of internal control over
financial  reporting  as  a  basis  for  designing  audit  procedures  that  are
appropriate  in the  circumstances,  but not for the  purpose of  expressing  an
opinion on the  effectiveness  of the Company's  internal control over financial
reporting.  Accordingly,  we express  no such  opinion.  An audit also  includes
examining,  on a test basis,  evidence supporting the amounts and disclosures in
the  financial  statements.  An audit also  includes  assessing  the  accounting
principles  used  and  significant  estimates  made  by  management,  as well as
evaluating the overall  financial  statement  presentation.  We believe that our
audits provide a reasonable basis for our opinion.

In our opinion,  these consolidated  financial statements present fairly, in all
material respects,  the financial position of Upstream  Biosciences,  Inc. as at
September 30, 2011 and 2010 and the results of its operations and its cash flows
for the years  then  ended and the  period  from June 14,  2004  (inception)  to
September 30, 2011 in conformity with accounting  principles  generally accepted
in the United States of America.

The accompanying  consolidated  financial statements have been prepared assuming
that the Company will continue as a going concern. As discussed in Note 1 to the
financial statements, the Company has a working capital deficiency, has incurred
losses in  developing  its business,  and further  losses are  anticipated.  The
Company  requires  additional funds to meet its obligations and the costs of its
operations. These factors raise substantial doubt about the Company's ability to
continue as a going concern.  Management's plans in this regard are described in
Note 1. The  financial  statements  do not  include any  adjustments  that might
result from the outcome of this uncertainty.


                                   /s/ Dale Matheson Carr-hilton Labonte LLP
                                   ---------------------------------------------
                                   DALE MATHESON CARR-HILTON LABONTE LLP
                                   CHARTERED ACCOUNTANTS

Vancouver, Canada
January 12, 2012

                                       20

                           UPSTREAM BIOSCIENCES, INC.
                          (A Development Stage Company)
                           CONSOLIDATED BALANCE SHEETS



                                                                        September 30,        September 30,
                                                                            2011                 2010
                                                                         ----------           ----------
                                                                                        
                                     ASSETS

CURRENT ASSETS
  Cash                                                                   $   12,602           $   31,152
  Other receivables                                                              --               10,259
  Prepaid expenses                                                              396                   --
                                                                         ----------           ----------
                                                                             12,998               41,411
                                                                         ----------           ----------
EQUIPMENT, net                                                                   --                1,338
                                                                         ----------           ----------

                                                                         $   12,998           $   42,749
                                                                         ==========           ==========

                                   LIABILITIES

CURRENT LIABILITIES
   Accounts payable and accrued liabilities                              $   36,513           $  185,822
   Due to related parties                                                    35,000                   --
                                                                         ----------           ----------
                                                                             71,513              185,822
DEFERRED INCOME TAX                                                              --                   --
                                                                         ----------           ----------
                                                                             71,513              185,822
                                                                         ----------           ----------

                              STOCKHOLDERS' DEFICIT

CAPITAL STOCK
  Authorized:
    100,000,000 non-voting preferred shares at $0.001 par value
    750,000,000 common shares at $0.001 par value
  Issued and outstanding:
    34,112,065 common shares (2010 - 34,112,065)                             34,112               34,112
ADDITIONAL PAID-IN CAPITAL                                                7,123,633            7,123,633
ACCUMULATED OTHER COMPREHENSIVE LOSS                                        (10,352)             (26,053)
DEFICIT ACCUMULATED DURING THE DEVELOPMENT STAGE                         (7,205,908)          (7,274,765)
                                                                         ----------           ----------
                                                                            (58,515)            (143,073)
                                                                         ----------           ----------

                                                                         $   12,998           $   42,749
                                                                         ==========           ==========



              The accompanying notes are an integral part of these
                       consolidated financial statements.

                                       21

                           UPSTREAM BIOSCIENCES, INC.
                          (A Development Stage Company)
                      CONSOLIDATED STATEMENTS OF OPERATIONS



                                                                                                    Cumulative Results
                                                                                                      From Inception
                                                                                                    (June 14, 2004) to
                                                              Years Ended September 30,                September 30,
                                                             2011                   2010                   2011
                                                         ------------           ------------           ------------
                                                                                              
REVENUE                                                  $         --           $         --           $     67,600
                                                         ------------           ------------           ------------
OPERATING EXPENSES
   Amortization                                                   175                    192                133,600
   Consulting fees                                                 --                     --                 12,598
   Interest and finance charges                                 2,535                 33,586                598,965
   Interest income                                                 --                 (1,339)               (84,671)
   Investor and corporate communications                           --                     --                258,349
   License fees and royalties                                   9,375                 24,016                114,384
   Loss on foreign exchange                                        --                  5,533                 15,453
   Management compensation                                         --                 72,245              1,526,086
   Office and general administration                           13,761                 37,402                487,557
   Professional fees                                           31,812                 76,196                622,675
   Research and development                                        --                     --              1,421,530
   Stock-based compensation                                        --                     --              2,090,632
                                                         ------------           ------------           ------------
                                                              (57,658)              (247,831)            (7,197,158)

OTHER ITEMS
   Asset impairment loss                                           --                     --                (59,010)
   Compensation shares                                             --                (25,000)               (25,000)
   Loss on sale of intellectual property                           --                (78,570)               (78,570)
   Gain on sale of subsidiary                                 126,515                     --                126,515
                                                         ------------           ------------           ------------
INCOME (LOSS) BEFORE INCOME TAX                                68,857               (351,401)            (7,165,623)
Deferred income tax recovery                                       --                 27,857                 57,415
                                                         ------------           ------------           ------------

NET INCOME (LOSS)                                        $     68,857           $   (323,544)          $ (7,108,208)
                                                         ============           ============           ============

NET INCOME (LOSS) PER SHARE - BASIC AND DILUTED          $       0.00           $      (0.01)
                                                         ============           ============
WEIGHTED AVERAGE NUMBER OF COMMON SHARES
OUTSTANDING - BASIC AND DILUTED                            34,112,065             36,844,724
                                                         ============           ============



              The accompanying notes are an integral part of these
                       consolidated financial statements.

                                       22

                           UPSTREAM BIOSCIENCES, INC.
                          (A Development Stage Company)
                            STATEMENTS OF CASH FLOWS



                                                                                                          Cumulative Results
                                                                                                            From Inception
                                                                                                          (June 14, 2004) to
                                                                        Years Ended September 30,            September 30,
                                                                       2011                 2010                 2011
                                                                   ------------         ------------         ------------
                                                                                                    
CASH FLOW FROM OPERATING ACTIVITIES
  Net loss                                                         $     68,857         $   (323,544)        $ (7,108,208)
  Adjustments to reconcile net loss to net cash used in
   operating activities:
     Amortization                                                           175                  192              133,600
     Accretion of convertible debenture                                      --                   --              302,808
     Shares issued or to be issued for services                              --                   --            1,487,236
     Stock-based compensation                                                --                   --            1,658,590
     Compensation shares                                                     --               25,000               25,000
     Deferred income tax                                                     --              (27,857)             (57,415)
     Asset impairment                                                        --                   --               59,010
     Gain on sale of subsidiary                                        (126,515)                  --             (126,515)
     Loss from sale of intellectual property                                 --               78,570               78,570
  Changes in operating assets and liabilities:
     Other receivables                                                       --               (7,695)             (10,259)
     Prepaid expenses                                                      (396)              29,234               (3,177)
     Accounts payable and accrued liabilities                             4,883               59,676              267,920
     Due to related parties                                                  --              (25,986)             271,984
                                                                   ------------         ------------         ------------
           NET CASH USED IN OPERATING ACTIVITIES                        (52,996)            (192,410)          (3,020,856)
                                                                   ------------         ------------         ------------

CASH FLOW FROM INVESTING ACTIVITIES
   Decrease in restricted cash                                               --               31,765                   --
   Cash paid for acquisition of PPT shares                                   --                   --              (51,507)
   Proceeds on the sale of subsidiary                                         1                   --                    1
   Purchase of equipment                                                     --               (1,530)             (22,764)
                                                                   ------------         ------------         ------------
           NET CASH PROVIDED BY (USED IN) INVESTING ACTIVITIES                1               30,235              (74,270)
                                                                   ------------         ------------         ------------

CASH FLOW FROM FINANCING ACTIVITIES
   Proceeds from issuance of convertible debentures                          --                   --            1,000,000
   Proceeds from issuance of common shares, net                              --                   --            1,995,345
   Loan from related party                                               35,000                   --              113,487
                                                                   ------------         ------------         ------------
           NET CASH PROVIDED BY FINANCING ACTIVITIES                     35,000                   --            3,108,832
                                                                   ------------         ------------         ------------
EFFECT OF EXCHANGE RATE CHANGES                                            (555)             (16,007)              (1,104)
                                                                   ------------         ------------         ------------
INCREASE (DECREASE) IN CASH                                             (18,550)            (178,182)              12,602
CASH, BEGINNING                                                          31,152              209,334                   --
                                                                   ------------         ------------         ------------

CASH, ENDING                                                       $     12,602         $     31,152         $     12,602
                                                                   ============         ============         ============



              The accompanying notes are an integral part of these
                       consolidated financial statements.

                                       23

                           UPSTREAM BIOSCIENCES, INC.
                          (A Development Stage Company)
                 CONSOLIDATED STATEMENT OF STOCKHOLDERS' DEFICIT
             FOR THE PERIOD FROM JUNE 14, 2004 TO SEPTEMBER 30, 2010




                                                                         Common Stock
                                                                     --------------------       Additional    Obligation
                                                                    Number of                    Paid-In       to Issue
                                                                     Shares         Amount       Capital        Shares
                                                                     ------         ------       -------        ------
                                                                                                  
BALANCE - JUNE 14, 2004                                            59,300,000      $59,300     $  (10,300)     $    --

Forward stock split on a 1.5:1 basis                               29,650,000       29,650        (29,650)          --
Comprehensive income (loss)
  Foreign exchange translation adjustment                                  --           --             --           --
  Net loss                                                                 --           --             --           --
                                                                  -----------      -------     ----------      -------
BALANCE - DECEMBER 31, 2005                                        88,950,000       88,950        (39,950)          --

Share exchange and recapitalization
  Shares issued to former shareholders of Upstream Canada          24,000,000       24,000             --           --
  Shares cancelled on acquisition                                 (68,650,000)      68,650             --           --
  Recapitalization adjustment                                              --           --         (4,005)          --
Fair value compensation to consultant
  Issuance of stock at $1.20 per share                                500,000          500        599,500           --
  Amortization of fair value of stock options granted                      --           --        100,150           --
Issuance of convertible debenture
  Fair value of detachable warrants                                        --           --        360,964           --
  Embedded beneficial conversion feature                                   --           --        268,108           --
Issuance of stock for services
  Prepaid for six months ended October 31, 2006                        17,500           18         17,750           --
  Less: amount expensed to September 30, 2006                              --           --             --           --
  Issuance of stock for BCCA license fee                               29,577           30         17,717           --
  Partial forfeiture of convertible debenture                              --           --        141,844           --
Comprehensive loss
  Foreign exchange translation adjustment                                  --           --             --           --
  Net loss                                                                 --           --             --           --
                                                                  -----------      -------     ----------      -------
BALANCE - SEPTEMBER 30, 2006                                       44,847,077       44,848      1,462,078           --

Amortization of fair value of stock options granted                        --           --        771,809           --
Amortization of stock issued for operating expenses                        --           --             --           --
Issuance of stock for services
  Prepaid for twelve months ended October 31, 2007                     48,326           48         34,674           --
  Less: amount expensed to September 30, 2007                              --           --             --           --
Issuance of stock for cash @ 1.50 per share                         1,333,334        1,333      1,998,667           --
Cash payment for unsuccessful due diligence                                --           --         (5,000)          --
Issuance of stock for convertible debenture
  Principal                                                           800,000          800        799,200           --
  Interest payable                                                     53,973           54         53,919           --
Issuance of stock for acquisition of PPT
  For 100% of PPT's shares                                            520,000          520        243,880           --
  For performance-based escrow shares as deferred compensation        225,000          225        105,525           --
Obligation to issue shares under contract                                  --           --             --        4,842
Comprehensive income (loss)
  Foreign exchange translation adjustment                                  --           --             --           --
  Net loss                                                                 --           --             --           --
                                                                  -----------      -------     ----------      -------
BALANCE - SEPTEMBER 30, 2007                                       47,827,710       47,828      5,464,752        4,842

Amortization of fair value of stock options granted                        --           --        424,128           --
Amortization of stock issued for operating expenses                        --           --             --           --
Issuance of stock for consulting services contract
  For six months ended January 31, 2008 @ $0.30 per share              83,183           83         24,872       (4,842)
  For amended and restated contract @ $0.25 per share                 403,388          403        100,445           --
  For six months ended August 31, 2008 @ $0.30 per share              213,725          214         46,841           --
Issuance of stock for achieving Malaria milestone
  New stock issued @ $0.3624/sh                                       925,000          925        334,295           --
  Release of 75,000 performance-based shares from escrow                   --           --             --           --
Obligation to issue shares under contract                                  --           --             --       14,391
Comprehensive income (loss)
  Foreign exchange translation adjustment                                  --           --             --           --
  Net loss                                                                 --           --             --           --
                                                                  -----------      -------     ----------      -------
BALANCE - SEPTEMBER 30, 2008                                       49,453,006       49,453      6,395,333       14,391

Amortization of fair value of stock options granted                        --           --        194,545           --
Forgiveness of related party debt                                          --      300,000             --           --
Obligation to issue shares under contract                                  --           --         85,346           --
Comprehensive income (loss)
Foreign exchange translation adjustment                                    --           --             --           --
Net loss                                                                   --           --             --           --
                                                                  -----------      -------     ----------      -------
BALANCE - SEPTEMBER 30, 2009                                       49,453,006      $49,453     $6,889,878      $99,737
                                                                  -----------      -------     ----------      -------

Forgiveness of related party debt                                          --           --        271,984           --
Issuance of stock as per agreement                                  1,000,000        1,000         24,000           --
Stock returned to treasury                                        (16,340,941)     (16,341)        16,341           --
Forgiveness of obligation to issue shares                                  --           --             --      (99,737)
Forgiveness of deferred compensation due to
 cancellation of escrow shares                                             --           --        (78,570)          --
Comprehensive income (loss)
  Foreign exchange translation adjustment                                  --           --             --           --
  Net loss                                                                 --           --             --           --
                                                                  -----------      -------     ----------      -------
BALANCE - SEPTEMBER 30, 2010                                       34,112,065       34,112      7,123,633           --
                                                                  -----------      -------     ----------      -------
Comprehensive income (loss)
  Foreign exchange translation adjustment                                  --           --             --           --
   Net income                                                              --           --             --           --
                                                                  -----------      -------     ----------      -------

BALANCE - SEPTEMBER 30, 2011                                       34,112,065      $34,112     $7,123,633      $    --
                                                                  ===========      =======     ==========      =======

                                                                                 Accumulated      Deficit
                                                                                   Other        Accumulated
                                                                                Comprehensive    During the       Total
                                                                   Deferred        Income       Development    Stockholders'
                                                                 Compensation      (Loss)          Stage          Equity
                                                                 ------------      ------          -----          ------
BALANCE - JUNE 14, 2004                                          $      --       $     --       $   (77,105)   $   (28,105)

Forward stock split on a 1.5:1 basis
Comprehensive income (loss)
  Foreign exchange translation adjustment                                --         (3,472)              --         (3,472)
  Net loss                                                               --             --          (50,205)       (50,205)
                                                                  ---------       --------      -----------    -----------
BALANCE - DECEMBER 31, 2005                                              --         (3,472)        (127,310)       (81,782)

Share exchange and recapitalization
  Shares issued to former shareholders of Upstream Canada                --             --               --         24,000
  Shares cancelled on acquisition                                        --             --               --        (68,650)
  Recapitalization adjustment                                            --             --          (49,045)       (53,050)
Fair value compensation to consultant
  Issuance of stock at $1.20 per share                                   --             --               --        600,000
  Amortization of fair value of stock options granted                    --             --               --        100,150
Issuance of convertible debenture
  Fair value of detachable warrants                                      --             --               --        360,964
  Embedded beneficial conversion feature                                 --             --               --        268,108
Issuance of stock for services
  Prepaid for six months ended October 31, 2006                     (17,768)            --               --             --
  Less: amount expensed to September 30, 2006                        14,986             --               --         14,986
  Issuance of stock for BCCA license fee                                 --             --               --         17,747
  Partial forfeiture of convertible debenture                            --             --               --        141,844
Comprehensive loss
  Foreign exchange translation adjustment                                --         (5,707)              --         (5,707)
  Net loss                                                               --             --       (1,843,529)    (1,843,529)
                                                                  ---------       --------      -----------    -----------
BALANCE - SEPTEMBER 30, 2006                                         (2,782)        (9,179)      (2,019,884)      (524,919)

Amortization of fair value of stock options granted                      --             --               --        771,809
Amortization of stock issued for operating expenses                   2,782             --               --          2,782
Issuance of stock for services
  Prepaid for twelve months ended October 31, 2007                  (34,722)            --               --             --
  Less: amount expensed to September 30, 2007                        31,600             --               --         31,600
Issuance of stock for cash @ 1.50 per share                              --             --               --      2,000,000
Cash payment for unsuccessful due diligence                              --             --               --         (5,000)
Issuance of stock for convertible debenture
  Principal                                                              --             --               --        800,000
  Interest payable                                                       --             --               --         53,973
Issuance of stock for acquisition of PPT
  For 100% of PPT's shares                                               --             --               --        244,400
  For performance-based escrow shares as deferred compensation     (105,750)            --               --             --
Obligation to issue shares under contract                                --             --               --          4,842
Comprehensive income (loss)
  Foreign exchange translation adjustment                                --         36,035               --         36,035
  Net loss                                                               --             --       (1,796,981)    (1,796,981)
                                                                  ---------       --------      -----------    -----------
BALANCE - SEPTEMBER 30, 2007                                       (108,872)        26,856       (3,816,865)     1,618,541

Amortization of fair value of stock options granted                                                                424,128
Amortization of stock issued for operating expenses                   3,122             --               --          3,122
Issuance of stock for consulting services contract
  For six months ended January 31, 2008 @ $0.30 per share                --             --               --         20,113
  For amended and restated contract @ $0.25 per share                    --             --               --        100,848
  For six months ended August 31, 2008 @ $0.30 per share                 --             --               --         47,055
Issuance of stock for achieving Malaria milestone
  New stock issued @ $0.3624/sh                                          --             --               --        335,220
  Release of 75,000 performance-based shares from escrow             27,180             --               --         27,180
Obligation to issue shares under contract                                --             --               --         14,391
Comprehensive income (loss)
  Foreign exchange translation adjustment                                --         (7,657)              --         (7,657)
  Net loss                                                               --             --       (2,034,502)    (2,034,502)
                                                                  ---------       --------      -----------    -----------
BALANCE - SEPTEMBER 30, 2008                                        (78,570)        19,199       (5,851,367)       548,439

Amortization of fair value of stock options granted                      --             --               --        194,545
Forgiveness of related party debt                                        --             --               --        300,000
Obligation to issue shares under contract                                --             --               --         85,346
Comprehensive income (loss)
Foreign exchange translation adjustment                                  --        (29,237)              --        (29,237)
Net loss                                                                 --             --       (1,099,854)    (1,099,854)
                                                                  ---------       --------      -----------    -----------
BALANCE - SEPTEMBER 30, 2009                                      $ (78,570)      $(10,038)     $(6,951,221)   $      (761)
                                                                  ---------       --------      -----------    -----------

Forgiveness of related party debt                                        --             --               --        271,984
Issuance of stock as per agreement                                       --             --               --         25,000
Stock returned to treasury                                               --             --               --             --
Forgiveness of obligation to issue shares                                --             --               --        (99,737)
Forgiveness of deferred compensation due to
 cancellation of escrow shares                                       78,570             --               --             --
Comprehensive income (loss)
  Foreign exchange translation adjustment                                --        (16,015)              --        (16,015)
  Net loss                                                               --             --         (323,544)      (323,544)
                                                                  ---------       --------      -----------    -----------
BALANCE - SEPTEMBER 30, 2010                                      $      --       $(26,053)     $(7,274,765)   $  (143,073)
                                                                  ---------       --------      -----------    -----------
Comprehensive income (loss)
  Foreign exchange translation adjustment                                --         15,701               --         15,701
  Net income                                                             --             --           68,857         68,857
                                                                  ---------       --------      -----------    -----------

BALANCE - SEPTEMBER 30, 2011                                      $      --       $(10,352)     $(7,205,908)   $   (58,515)
                                                                  =========       =-======      -==========    ===========


              The accompanying notes are an integral part of these
                       consolidated financial statements.

                                       24

                            UPSTREAM BIOSCIENCES, INC
                          (A Development Stage Company)
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                               September 30, 2011


1. NATURE OF BUSINESS AND CONTINUANCE OF OPERATIONS

Upstream  Biosciences,  Inc. ("the Company") was  incorporated on March 20, 2002
under the laws of the State of Nevada.  The  Company  is  engaged in  developing
technology relating to biomarker identification, disease susceptibility and drug
response areas of cancer.

GOING CONCERN
These  consolidated  financial  statements have been prepared in accordance with
accounting  principles  generally  accepted in the United States of America ("US
GAAP") on a going concern basis,  which  contemplates  the realization of assets
and the  satisfaction  of  liabilities  and  commitments in the normal course of
business. As at September 30, 2011, the Company has a working capital deficiency
of $58,515 and has incurred  losses since  inception of $7,108,208.  This raises
substantial  doubt about the  Company's  ability to continue as a going  concern
which is dependent  upon  generating  profitable  operations  and  obtaining the
necessary  financing to meet its  obligations  when they become due. There is no
assurance that equity or debt capital will be available as necessary to meet the
Company's requirements or, if the capital is available, that it will be on terms
acceptable to the Company.

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

BASIS OF PRESENTATION AND CONSOLIDATION
These  consolidated  financial  statements  and related  notes are  presented in
accordance  with United States  generally  accepted  accounting  principles ("US
GAAP") and are expressed in US dollars.  The Company is in the development stage
and has not realized  significant revenues from its business plan to date. These
financial  statements  include the accounts of the Company and its  wholly-owned
Canadian subsidiaries,  Upstream Biosciences, Inc. ("Upstream Canada") up to the
date of its sale on February 15, 2011 (Note 4) and Pacific  Pharma  Technologies
Inc.  ("PPT").  All  inter-company  transactions  and account balances have been
eliminated on consolidation.

The Company acquired  Upstream Canada on February 24, 2006. This transaction was
accounted  for  as  a  recapitalization   transaction,   similar  to  a  reverse
acquisition  accounting,  with Upstream  Canada being treated as the  accounting
parent  (legal  subsidiary)  and the  Company  being  treated as the  accounting
subsidiary (legal parent).  Accordingly,  the consolidated results of operations
of the  Company  include  those  of  Upstream  Canada  for the  period  from its
inception  on June 14,  2004 to the date of its sale on  February  15,  2011 and
those of the Company  since the date of the reverse  acquisition,  February  24,
2006.

EQUIPMENT
Equipment  is valued  at cost less  accumulated  amortization.  Amortization  is
recorded  using the  straight-line  method over four years and  maintenance  and
repairs are expensed as incurred.

USE OF ESTIMATES AND ASSUMPTIONS
The preparation of financial  statements in conformity with US GAAP requires the
Company to make estimates and  assumptions  that affect the reported  amounts of
assets and  liabilities  and disclosure of contingent  assets and liabilities at
the date of the  financial  statements  and the reported  amounts of revenue and
expenses  during the  reporting  period.  The Company  bases its  estimates  and
assumptions  on current facts,  historical  experience and various other factors
that it believes to be reasonable under the circumstances,  the results of which
form the basis for  making  judgments  about the  carrying  values of assets and
liabilities and the accrual of costs and expenses that are readily apparent from
other  sources.  The  actual  results  experienced  by the  Company  may  differ
materially  from the  Company's  estimates.  To the  extent  there are  material
differences,  future results may be affected.  Estimates used in preparing these
financial  statements include the fair value of share-based  payments,  deferred
income taxes, financial instruments and assumptions relating to going concern.

SHARE-BASED COMPENSATION
The Company  accounts for share-based  compensation  using the fair value method
and related  compensation  expense is recognized over the period of benefit when
the service is rendered.

                                       25

FINANCIAL INSTRUMENTS
The Company's financial instruments consist of cash, other receivables, accounts
payable  and  amounts  due to related  parties.  The  carrying  amounts of these
financial  instruments  at September  30, 2011 and 2010  approximate  their fair
values due to their short term nature.

FOREIGN CURRENCY TRANSACTIONS AND TRANSLATION
The  functional  currency of the Company is the Canadian  dollar.  The financial
statements are translated into United States dollars using  period-end  rates of
exchange for assets and  liabilities,  and period  average rates of exchange for
revenues and expenses.  Foreign currency gains (losses) arising from translation
are  included in other  comprehensive  income  (loss)  which is  disclosed  as a
separate  component of shareholders'  deficit.  The Company has not entered into
any   derivative   instruments   to  offset  the  impact  of  foreign   currency
fluctuations.

RESEARCH AND DEVELOPMENT
These costs are expensed when incurred and consist  primarily of direct material
and  personnel  costs,  contract  services and indirect  costs.  The Company has
received  government  assistance  in the past and may receive same in the future
regarding its research and  development  activities.  When the work is performed
that  qualifies for such grants,  the related  assistance  amount is credited to
research and development expense.

INCOME TAXES
The Company uses the asset and liability  method of accounting for income taxes.
Under this method,  deferred tax assets and liabilities are determined  based on
temporary  differences  between the  financial  statements  and the tax basis of
assets and  liabilities,  and net operating  loss carry  forwards based on using
enacted tax rates in effect for the year in which the  differences  are expected
to  reverse.  The  effect of a change in tax rates on  deferred  tax  assets and
liabilities  is  recognized  in income in the year that  includes the  enactment
date.  Deferred  tax  assets  are  only  recognized  to the  extent  that  it is
considered  more likely than not that the assets will be realized.  At September
30, 2011 and 2010, a valuation allowance for the full amount of the deferred tax
assets was recorded.

EARNINGS (LOSS) PER SHARE
Basic  earnings  (loss) per share is computed  by  dividing  the net loss by the
weighted  average number of outstanding  common shares during the year.  Diluted
loss  per  share  gives  effect  to  all  potentially   dilutive  common  shares
outstanding during the year, including convertible debt, stock options and share
purchase  warrants,  using the treasury stock method. The computation of diluted
loss per share does not assume  conversion,  exercise or contingent  exercise of
securities that would have an anti-dilutive effect on loss per share.

NEW ACCOUNTING PRONOUNCEMENTS AND POLICIES
The Company has reviewed recently issued accounting  pronouncements and plans to
adopt those that are  applicable to it. It does not expect the adoption of these
pronouncements  to have a material  impact on its reported  financial  position,
results of operations or cash flows.

3. INTELLECTUAL PROPERTY

Pursuant  to an  agreement  dated  December  14,  2009,  the  Company  sold  its
intellectual  property  for  proceeds  of  $1.  The  agreement  resulted  in the
cancellation  of the  Company's  obligation  to  issue  shares  with a value  of
$99,737, resulting in a loss on disposal of $78,570.

4. SALE OF SUBSIDIARY

On February 15, 2011,  the Company  sold its wholly owned  Canadian  subsidiary,
Upstream  Biosciences,  Inc. to an arms length party,  for  consideration of $1,
realizing a gain on disposal of $126,515.

5. RELATED PARTY TRANSACTIONS

For the year ended September 30, 2011, the Company  incurred  expenses of $7,421
(2010 - $72,245) to management, directors, or companies controlled by directors.

As at  September  30, 2011,  the Company owed $35,000  (2010 - $nil) to the sole
director  and officer of the  Company.  The balance  relates to a loan  advances
during the year and is unsecured, does not bear interest and is due on demand.

                                       26

During the year ended  September 30, 2010,  $271,984  owing to the directors was
forgiven.  The  forgiveness  of debt was  treated as a capital  transaction  and
recorded as Additional Paid in Capital in the consolidated financial statements.

During the year ended  September  30, 2010,  16,190,941  shares were returned to
treasury and cancelled for no  consideration  by two directors of the Company in
connection with their resignation.

During the year ended  September  30, 2010,  the Company  sold its  intellectual
property for proceeds of $1 to a former member of the Company's  management.  In
connection with this transaction, its obligation to issue shares with a value of
$99,737 was cancelled,  and deferred compensation expense of $78,570,  which was
included in shareholders' deficit, was reversed upon the cancellation of 150,000
performance-based escrow shares.

6. INCOME TAXES

A reconciliation of the Company's  expected income tax provision compared to the
actual tax provision is as follows:

                                                 Year ended         Year ended
                                                September 30,      September 30,
                                                    2011               2010
                                                 ----------         ----------
Income (loss) before income taxes                $   68,857         $ (351,401)
Corporate tax rate                                       35%                35%
                                                 ----------         ----------
Expected tax recovery                                24,100           (122,990)
Increase (decrease) resulting from:
  Permanent differences                             (44,280)           197,886
  Deferred tax assets of subsidiary sold
   during the year                                  864,807                 --
  Differences in foreign tax rates                       --             39,074
  Change in valuation allowance                    (844,627)          (141,827)
                                                 ----------         ----------

                                                 $       --         $  (27,857)
                                                 ==========         ==========

At September 30, 2011 and 2010, the components of the deferred income tax assets
and liabilities are as follows:

                                                 Year ended         Year ended
                                                September 30,      September 30,
                                                    2011               2010
                                                 ----------         ----------
Tax loss carry forwards                          $  130,815         $  970,053
Other deferred tax assets                             3,231              8,620
                                                 ----------         ----------
Total deferred tax assets                           134,046            978,673
Less: Valuation allowance                          (134,046)          (978,673)
                                                 ----------         ----------

                                                 $       --         $       --
                                                 ==========         ==========

The  Company is subject to income  taxes in the  United  States of  America.  At
September 30, 2011, the Company had total accumulated tax loss carry-forwards of
approximately  $374,000.  These losses are available to reduce taxable income in
future taxation years and begin to expire in 2025 after a  carry-forward  period
of 20 years. The Company is required to compute the deferred income tax benefits
from the tax loss carry-forwards and other temporary  differences.  However, due
to the  uncertainty  of  realization  of  these  tax  assets,  a full  valuation
allowance has been provided.

                                       27

7. CAPITAL STOCK

A) AUTHORIZED

The  authorized  capital  stock  of the  Company  is  comprised  of  100,000,000
non-voting  preferred shares and 750,000,000  voting common shares,  both with a
par value of $0.001 per share.

B) ISSUED AND OUTSTANDING No preferred shares have been issued to date.

During the year ended September 30, 2011, there were no changes in common stock.

During the year ended  September  30, 2010,  the changes in common stock were as
follows:

     (i)  On November 17, 2009,  1,000,000 shares were issued with a fair market
          value of $25,000  pursuant to the terms of an  agreement  dated August
          24,  2007  regarding  the  purchase  of PPT,  whereby  the Company was
          obligated  to issue these  shares  since the minimum  $150,000 was not
          expended on third-party  testing of the PPT technology during the year
          ended September 30, 2009.

     (ii) On December 4, 2009,  16,190,941  shares were returned to treasury and
          cancelled  for no  consideration  by two  directors  of the Company in
          connection with their resignation.

     (iii)Pursuant  to  an  agreement  dated  December  10,  2009  to  sell  the
          Company's  intellectual  property (Note 3), 150,000  performance-based
          escrow  shares,  recorded  as  deferred  compensation  of  $78,570  in
          shareholders' deficit, were cancelled and returned to treasury.

C) STOCK OPTIONS

The Company has a stock option plan (the "Plan")  authorizing the issuance of up
to  5,000,000  shares of common  stock  upon  exercise  of the  options  granted
pursuant  to the Plan.  Under  the Plan,  the  Company's  employees,  directors,
officers,  consultants  and advisors  (collectively  the  "Optionee  Group") are
eligible to receive a grant of the Company's options, provided however that bona
fide services are rendered by  consultants or advisors and such services are not
in  connection  with  the  offer  or sale  of  securities  in a  capital-raising
transaction.

During the years ended September 30, 2011 and 2010 the Company did not grant any
stock options.

A summary of transactions involving stock options is as follows:

                                        Year ended              Year ended
                                    September 30, 2011      September 30, 2010
                                    ------------------      ------------------
                                               Weighted                 Weighted
                                               average                  average
                                   Number of   exercise    Number of    exercise
                                    options     price       options      price
                                    -------     -----       -------      -----
Outstanding, beginning of year      800,000      1.02       2,000,000     0.95
Expired                                  --        --      (1,200,000)    0.91
                                   --------      ----      ----------     ----

Outstanding, end of year            800,000      1.02         800,000     1.02
                                   ========      ====      ==========     ====

Exercisable, end of year            800,000      1.02         800,000     1.02
                                   ========      ====      ==========     ====

                                       28

At September 30, 2011,  800,000 stock options were  outstanding  with a weighted
average exercise price and remaining life of $1.02 and 0.48 years respectively.

D) SHARE PURCHASE WARRANTS

There are no stock purchase warrants outstanding at September 30, 2011 and 2010.

8. CONTINGENCIES

An  individual  has  alleged a breach of contract by the Company and has filed a
claim in the amount $500,000 plus interest of $114,000 (as at November 26, 2010)
against  the  Company  and its  directors.  The  Company  refuted  the claims on
December 13, 2010 and there have been no further developments since that time.

                                       29

ITEM 9. CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND
        FINANCIAL DISCLOSURE

None.

ITEM 9A. CONTROLS AND PROCEDURES

DISCLOSURE CONTROLS AND PROCEDURES

As required by paragraph (b) of Rules 13a-15 or 15d-15 under the Exchange Act,
our principal executive officer and principal financial officer evaluated our
company's disclosure controls and procedures (as defined in Rules 13a-15(e) and
15d-15(e) of the Exchange Act) as of the end of the period covered by this
annual report on Form 10-K. Based on this evaluation, these officers concluded
that as of the end of the period covered by this annual report on Form 10-K,
these disclosure controls and procedures were not effective to ensure that the
information required to be disclosed by our company in reports it files or
submits under the Exchange Act is recorded, processed, summarized and reported
within the time periods specified in the rules and forms of the Securities
Exchange Commission and include controls and procedures designed to ensure that
such information is accumulated and communicated to our company's management,
including our company's principal executive officer and principal financial
officer, to allow timely decisions regarding required disclosure. The conclusion
that our disclosure controls and procedures were not effective was due to the
presence of material weaknesses in internal control over financial reporting as
identified below under the heading "Management's Report on Internal Control Over
Financial Reporting." Management anticipates that such disclosure controls and
procedures will not be effective until the material weaknesses are remediated.
Our company intends to remediate the material weaknesses as set out below.

Because of the inherent limitations in all control systems, no evaluation of
controls can provide absolute assurance that all control issues, if any, within
our company have been detected. These inherent limitations include the realities
that judgments in decision-making can be faulty and that breakdowns can occur
because of simple error or mistake.

MANAGEMENT'S REPORT ON INTERNAL CONTROL OVER FINANCIAL REPORTING

Our company's management is responsible for establishing and maintaining
adequate internal control over financial reporting (as defined in Rules
13a-15(f) and 15d-15(f) of the Exchange Act) for our company. Our company's
internal control over financial reporting is designed to provide reasonable
assurance, not absolute assurance, regarding the reliability of financial
reporting and the preparation of financial statements for external purposes in
accordance with generally accepted accounting principles in the United States of
America. Internal control over financial reporting includes those policies and
procedures that: (i) pertain to the maintenance of records that, in reasonable
detail, accurately and fairly reflect the transactions and dispositions of our
company's assets; (ii) provide reasonable assurance that transactions are
recorded as necessary to permit preparation of financial statements in
accordance with generally accepted accounting principles in the United States of
America, and that our company's receipts and expenditures are being made only in
accordance with authorizations of our management and directors; and (iii)
provide reasonable assurance regarding prevention or timely detection of
unauthorized acquisition, use or disposition of our assets that could have a
material effect on the financial statements.

Because of its inherent limitations, internal control over financial reporting
may not prevent or detect misstatements. In addition, projections of any
evaluation of effectiveness to future periods are subject to the risk that
controls may become inadequate because of changes in conditions and that the
degree of compliance with the policies or procedures may deteriorate.

Our management, including our principal executive officer and principal
financial officer, conducted an evaluation of the design and operation of our
internal control over financial reporting as of September 30, 2011 based on the
criteria set forth in Internal Control - Integrated Framework issued by the
Committee of Sponsoring Organizations of the Treadway Commission. This
evaluation included review of the documentation of controls, evaluation of the
design effectiveness of controls, testing of the operating effectiveness of
controls and a conclusion on this evaluation. Based on this evaluation, our
management concluded our internal control over financial reporting was not
effective as at September 30, 2011 due to the following material weaknesses
which are indicative of many small companies with small staff: (i) inadequate
segregation of duties and effective risk assessment; (ii) insufficient written
policies and procedures for accounting and financial reporting with respect to

                                       30

the requirements and application of both US GAAP and SEC guidelines; (iii)
inadequate security and restricted access to computer systems including
insufficient disaster recovery plans; and (iv) no written whistle-blower policy.

Our company plans to take steps to enhance and improve the design of our
internal controls over financial reporting. During the period covered by this
annual report on Form 10-K, we have not been able to remediate the material
weaknesses identified above. To remediate such weaknesses, we plan to implement
the following changes during our fiscal year ending September 30, 2012: (i)
appoint additional qualified personnel to address inadequate segregation of
duties and ineffective risk management; (ii) adopt sufficient written policies
and procedures for accounting and financial reporting and a whistle-blower
policy; and (iii) implement sufficient security and restricted access measures
regarding our computer systems and implement a disaster recovery plan. The
remediation efforts set out in (i) and (iii) are largely dependent upon our
company securing additional financing to cover the costs of implementing the
changes required. If we are unsuccessful in securing such funds, remediation
efforts may be adversely effected in a material manner.

This annual report does not include an attestation report of our independent
registered public accounting firm regarding internal control over financial
reporting. Our internal control over financial reporting was not subject to
attestation by our independent registered public accounting firm pursuant to
temporary rules of the Securities and Exchange Commission that permit us to
provide only management's report in this annual report.

Because of the inherent limitations in all control systems, no evaluation of
controls can provide absolute assurance that all control issues, if any, within
our company have been detected. These inherent limitations include the realities
that judgments in decision-making can be faulty and that breakdowns can occur
because of simple error or mistake.

CHANGES IN INTERNAL CONTROL OVER FINANCIAL REPORTING.

There were no changes in our company's internal control over financial reporting
during the quarter ended September 30, 2011 that have materially affected, or
are reasonably likely to materially affect, our company's internal control over
financial reporting.

ITEM 9B. OTHER INFORMATION

None.

                                    PART III

ITEM 10. DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE

DIRECTORS AND EXECUTIVE OFFICERS

As at January 13, 2012, our directors and executive officers, their ages,
positions held, and duration of such, are as follows:

                                                              Date First Elected
Name              Position Held with the Company      Age        or Appointed
----              ------------------------------      ---        ------------
Mike              President, Secretary, Treasurer,    53      December 14, 2009
McFarland(1)(2)   Chief  Executive Officer, Chief
                  Financial Officer and Director

----------
(1)  Member of the Compensation Committee
(2)  Member of the Audit Committee

BUSINESS EXPERIENCE

The following is a brief account of the education and business experience of
each director and executive officer during at least the past five years,
indicating each person's principal occupation during the period, and the name
and principal business of the organization by which he was employed.

                                       31

MIKE MCFARLAND

Mike McFarland was appointed as a director and the president, secretary,
treasurer, chief executive officer and chief financial officer of our company on
December 14, 2009. Mr. McFarland earned his Bachelor of Science degree in 1982
and his Bachelor of Education in 1984, both from St. Francis Xavier University.
Mr. McFarland has been in the education and teaching profession for over 25
years. Since 2005, he has been teaching at Notre Dame High School in Calgary,
Alberta. He has been an active investor in both private and public ventures for
the past 12 years.

We believe Mr. McFarland is qualified to serve on our board of directors because
of his knowledge of our company's history and current operations, which he
gained from working for our company as described above, in addition to his
education and business experience as described above.

SIGNIFICANT EMPLOYEES

We have no significant employees other than the sole director and officer of our
company.

FAMILY RELATIONSHIPS

There are no family relationships among our directors or officers.

INVOLVEMENT IN CERTAIN LEGAL PROCEEDINGS

Our sole director and executive officer has not been involved in any of the
following events during the past ten years:

     1.   any bankruptcy petition filed by or against any business of which such
          person was a general partner or executive officer either at the time
          of the bankruptcy or within two years prior to that time;
     2.   any conviction in a criminal proceeding or being subject to a pending
          criminal proceeding (excluding traffic violations and other minor
          offences);
     3.   being subject to any order, judgment, or decree, not subsequently
          reversed, suspended or vacated, of any court of competent
          jurisdiction, permanently or temporarily enjoining, barring,
          suspending or otherwise limiting his involvement in any type of
          business, securities or banking activities;
     4.   being found by a court of competent jurisdiction (in a civil action),
          the Securities and Exchange Commission or the Commodity Futures
          Trading Commission to have violated a federal or state securities or
          commodities law, and the judgment has not been reversed, suspended, or
          vacated;
     5.   being the subject of, or a party to, any federal or state judicial or
          administrative order, judgment, decree, or finding, not subsequently
          reversed, suspended or vacated, relating to an alleged violation of:
          (i) any federal or state securities or commodities law or regulation;
          or (ii) any law or regulation respecting financial institutions or
          insurance companies including, but not limited to, a temporary or
          permanent injunction, order of disgorgement or restitution, civil
          money penalty or temporary or permanent cease- and-desist order, or
          removal or prohibition order; or (iii) any law or regulation
          prohibiting mail or wire fraud or fraud in connection with any
          business entity; or
     6.   being the subject of, or a party to, any sanction or order, not
          subsequently reversed, suspended or vacated, of any self-regulatory
          organization (as defined in Section 3(a)(26) of the Securities
          Exchange Act of 1934), any registered entity (as defined in Section
          1(a)(29) of the Commodity Exchange Act), or any equivalent exchange,
          association, entity or organization that has disciplinary authority
          over its members or persons associated with a member.

AUDIT COMMITTEE

Mike McFarland has been appointed as the sole member of the audit committee. Mr.
McFarland is not an independent director of our company as defined by Rule
4200(a)(15) of the Nasdaq Marketplace Rules. Our audit committee undertakes an

                                       32

independent review of our company's financial statements, and meets with
management to determine the adequacy of internal controls and other financial
reporting matters.

AUDIT COMMITTEE FINANCIAL EXPERT

Our board of directors has determined that it does not have an audit committee
member that qualifies as an "audit committee financial expert" as defined in
Item 407(d)(5)(ii) of Regulation S-K. We believe that the sole audit committee
member is capable of analyzing and evaluating our financial statements and
understanding internal controls and procedures for financial reporting. In
addition, we believe that retaining an independent director who would qualify as
an "audit committee financial expert" would be overly costly and burdensome and
is not warranted in our circumstances given the early stages of our development
and the fact that we have not generated revenues to date.

NOMINATION PROCEDURES FOR APPOINTMENT OF DIRECTORS

As of January 13, 2012, we did not effect any material changes to the procedures
by which our stockholders may recommend nominees to our board of directors.

CODE OF ETHICS

Effective January 29, 2004, our company's board of directors adopted a Code of
Business Conduct and Ethics that applies to, among other persons, members of our
board of directors, our company's officers, contractors, consultants and
advisors. As adopted, our Code of Business Conduct and Ethics sets forth written
standards that are designed to deter wrongdoing and to promote:

     (1)  honest and ethical conduct, including the ethical handling of actual
          or apparent conflicts of interest between personal and professional
          relationships;
     (2)  full, fair, accurate, timely, and understandable disclosure in reports
          and documents that we file with, or submit to, the Securities and
          Exchange Commission and in other public communications made by us;
     (3)  compliance with applicable governmental laws, rules and regulations;
     (4)  the prompt internal reporting of violations of the Code of Business
          Conduct and Ethics to an appropriate person or persons identified in
          the Code of Business Conduct and Ethics; and
     (5)  accountability for adherence to the Code of Business Conduct and
          Ethics.

Our Code of Business Conduct and Ethics requires, among other things, that all
of our company's personnel shall be accorded full access to our president with
respect to any matter which may arise relating to the Code of Business Conduct
and Ethics. Further, all of our company's personnel are to be accorded full
access to our company's board of directors if any such matter involves an
alleged breach of the Code of Business Conduct and Ethics by our company
officers.

In addition, our Code of Business Conduct and Ethics emphasizes that all
employees, and particularly managers and/or supervisors, have a responsibility
for maintaining financial integrity within our company, consistent with
generally accepted accounting principles, and federal, provincial and state
securities laws. Any employee who becomes aware of any incidents involving
financial or accounting manipulation or other irregularities, whether by
witnessing the incident or being told of it, must report it to his or her
immediate supervisor or to our company's President. If the incident involves an
alleged breach of the Code of Business Conduct and Ethics by the President, the
incident must be reported to any member of our board of directors. Any failure
to report such inappropriate or irregular conduct of others is to be treated as
a severe disciplinary matter. It is against our company policy to retaliate
against any individual who reports in good faith the violation or potential
violation of our company's Code of Business Conduct and Ethics by another.

We will provide a copy of the Code of Business Conduct and Ethics to any person
without charge, upon request. Requests can be sent to our company at the address
on the cover of this annual report.

                                       33

SECTION 16(A) BENEFICIAL OWNERSHIP COMPLIANCE

Section 16(a) of the Securities Exchange Act requires our executive officers and
directors, and persons who own more than 10% of our common stock, to file
reports regarding ownership of, and transactions in, our securities with the
Securities and Exchange Commission and to provide us with copies of those
filings. Based solely on our review of the copies of such forms received by us,
or written representations from certain reporting persons, we believe that
during the fiscal year ended September 30, 2011, all filing requirements
applicable to our officers, directors and greater than 10% percent beneficial
owners were complied with.

ITEM 11. EXECUTIVE COMPENSATION

The following table sets forth all compensation received during the two years
ended September 30, 2011 by our Chief Executive Officer, Chief Financial Officer
and each of the other most highly compensated executive officers whose total
compensation exceeded $100,000 in such fiscal year. These officers are referred
to as the Named Executive Officers in this Report.

SUMMARY COMPENSATION

The following table provides a summary of the compensation received by the
persons set out therein for each of our last two fiscal years:

SUMMARY COMPENSATION TABLE

                           SUMMARY COMPENSATION TABLE


                                                                                        Change in
                                                                                         Pension
                                                                                        Value and
                                                                       Non-Equity      Nonqualified
 Name and                                                              Incentive         Deferred
 Principal                                     Stock      Option          Plan         Compensation    All Other
 Position           Year  Salary($) Bonus($)  Awards($)  Awards($)(4) Compensation($)   Earnings($)  Compensation($) Totals($)
 --------           ----  --------- --------  ---------  ---------    ---------------   -----------  --------------- ---------
                                                                                          
Mike McFarland(1)   2011    Nil       Nil       Nil         Nil            Nil              Nil          Nil            Nil
Chief Executive     2010    Nil       Nil       Nil         Nil            Nil              Nil          Nil            Nil
Officer, Chief
Financial Officer,
President, Secretary
Treasurer and
Director

Joel L.             2011    N/A       N/A       N/A        N/A             N/A              N/A          N/A            N/A
Bellenson(2)        2010    Nil       Nil       Nil        Nil             Nil              Nil          Nil            Nil
Chief Executive
Officer, Chief
Financial Offer
and Director

Dexster L. Smith(3) 2011    N/A       N/A       N/A        N/A             N/A              N/A          N/A            N/A
President and       2010    Nil       Nil       Nil        Nil             Nil              Nil          Nil            Nil
Director

----------
(1)  Mike McFarland was appointed as chief executive officer, chief financial
     officer, president, secretary, treasurer and director on December 14, 2009.
(2)  Joel Bellenson was appointed director and chief executive officer of our
     company on March 1, 2006. Mr. Bellenson was appointed our chief financial
     officer on August 28, 2009. Mr. Bellenson resigned as an officer and
     director on December 14, 2009.
(3)  Dexster Smith was appointed director and president of our company on March
     1, 2006. Mr. Smith resigned as an officer and director on December 4, 2009.
(4)  The determination of value of option awards is based upon the Black-Scholes
     Option pricing model, details and assumptions of which are set out in our
     financial statements included in this annual report. The amounts represent
     annual amortization of fair value of stock options granted to the named
     executive officer.

                                       34

COMPENSATION DISCUSSION AND ANALYSIS

Our compensation program for our executive officers is administered and reviewed
by our board of directors and the Compensation Committee. Historically,
executive compensation consists of a combination of base salary and bonuses.
Individual compensation levels are designed to reflect individual
responsibilities, performance and experience, as well as the performance of our
company. The determination of discretionary bonuses is based on various factors,
including implementation of our business plan, acquisition of assets,
development of corporate opportunities and completion of financing. The
objectives of our compensation program are to retain and offer an incentive to
current management, and to carry out our compensation related policies as per
our Compensation Committee Charter.

OUTSTANDING EQUITY AWARDS AT FISCAL YEAR-END

The following table sets forth for each named executive officer certain
information concerning the outstanding equity awards as of September 30, 2011.

                  OUTSTANDING EQUITY AWARDS AT FISCAL YEAR-END



                                      Option Awards                                              Stock Awards
          -------------------------------------------------------------------  ---------------------------------------------
                                                                                                                     Equity
                                                                                                                    Incentive
                                                                                                         Equity       Plan
                                                                                                        Incentive    Awards:
                                                                                                          Plan      Market or
                                                                                                         Awards:     Payout
                                               Equity                                                   Number of   Value of
                                              Incentive                           Number                Unearned    Unearned
                                             Plan Awards;                           of        Market     Shares,     Shares,
            Number of         Number of       Number of                           Shares     Value of   Units or    Units or
           Securities        Securities      Securities                          or Units   Shares or    Other        Other
           Underlying        Underlying      Underlying                          of Stock    Units of    Rights      Rights
           Unexercised       Unexercised     Unexercised    Option     Option      That     Stock That    That        That
            Options            Options        Unearned     Exercise  Expiration  Have Not    Have Not   Have Not    Have Not
Name      Exercisable(#)(1) Unexercisable(#)  Options(#)(2) Price($)    Date     Vested(#)   Vested($)  Vested(#)   Vested(#)
----      --------------    ---------------- ----------     -----       ----     ---------   ---------  ---------   ---------
                                                                                        
Mike           Nil                Nil            Nil         Nil         Nil        Nil         Nil        Nil         Nil
McFarland(3)
Chief Executive
Officer,
Chief Financial
Officer,
President,
Secretary
Treasurer
and Director

Joel L.        Nil                Nil            Nil(5)      Nil         Nil         Nil        Nil         Nil         Nil
Bellenson(4)
former Chief
Executive
Officer,
Chief
Financial
Officer and
Director

Dexster L.     Nil                Nil            Nil(5)      Nil         Nil         Nil        Nil         Nil         Nil
Smith(6)
former
President
and Director


                                       35

----------
(1)  Represents options granted to the named executive officer that have vested.
(2)  Represents options granted to the named executive officer that have not yet
     vested.
(3)  Mike McFarland was appointed as chief executive officer, chief financial
     officer, president, secretary, treasurer and director on December 14, 2009.
(4)  Joel Bellenson was appointed director and chief executive officer of our
     company on March 1, 2006. Mr. Bellenson was appointed our chief financial
     officer on August 28, 2009. Mr. Bellenson resigned as an officer and
     director on December 14, 2009.
(5)  On December 14, 2009, these options were cancelled.
(6)  Dexster Smith was appointed director and president of our company on March
     1, 2006. Mr. Smith resigned as an officer and director on December 4, 2009.

No options were granted during the year ended September 30, 2011. At September
30, 2011, there were 800,000 stock options issued and outstanding.

In March 2007, our company approved and adopted a stock option plan authorizing
the issuance of up to 5,000,000 shares of common stock upon exercise of the
options granted pursuant to the plan. Under the plan, our employees, directors,
officers, consultants and advisors are eligible to receive a grant of our
shares, provided however that bona fide services are rendered by consultants or
advisors and such services are not in connection with the offer or sale of
securities in a capital-raising transaction.

A summary of our outstanding stock options as of September 30, 2011 is presented
below:

                                                                Options
                                                             Outstanding at
Grant Date         Expiry Date       Exercise Price        September 30, 2010
----------         -----------       --------------        ------------------
March 16, 2007     March 16, 2012     $0.96-$1.00                700,000
May 3, 2007        May 3, 2012        $1.41                      100,000
                                                                 -------
TOTALS                                                           800,000
                                                                 =======

AGGREGATED OPTION EXERCISES

There were no options exercised by any officer or director of our company during
our twelve month period ended September 30, 2011.

LONG-TERM INCENTIVE PLAN

Currently, our company does not have a long-term incentive plan in favor of any
director, officer, consultant or employee of our company.

DIRECTORS COMPENSATION

The particulars of compensation paid to our directors for our year ended
September 30, 2011, is set out in the following director compensation table:

                                       36



                                                                                Change in
                                                                                 Pension
                                                                                Value and
                           Fees                                Non-Equity      Nonqualified
                          Earned                               Incentive         Deferred
                         Paid in      Stock      Option          Plan          Compensation      All Other
    Name                 Cash($)     Awards($)  Awards($)(1) Compensation($)    Earnings($)    Compensation($)   Total($)
    (a)                    (b)         (c)         (d)           (e)               (f)             (g)             (h)
    ----                 -------     ---------  ---------    ---------------    -----------    ---------------   --------
                                                                                            
Mike McFarland(1)          Nil         Nil         Nil            Nil              Nil             Nil              Nil


----------
(1)  Mike McFarland was appointed as a director of our company on December 14,
     2009.

Independent directors may be paid their expenses for attending each board of
directors meeting and may be paid a fixed sum for attendance at each meeting of
the directors or a stated salary as director. No payment precludes any director
from serving our company in any other capacity and being compensated for the
service. Members of special or standing committees may be allowed like
reimbursement and compensation for attending committee meetings.

PENSION AND RETIREMENT PLANS

Currently, we do not offer any annuity, pension or retirement benefits to be
paid to any of our officers, directors or employees, in the event of retirement.

ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND
         RELATED STOCKHOLDER MATTERS

As of January 13, 2012, there were 34,112,065 shares of our common stock
outstanding. The following table sets forth certain information known to us with
respect to the beneficial ownership of our common stock as of that date by (i)
each of our directors, (ii) each of our executive officers, and (iii) all of our
directors and executive officers as a group. Except as set forth in the table
below, there is no person known to us who beneficially owns more than 5% of our
common stock.



Name and Address of                                           Amount and Nature of        Percentage
 Beneficial Owner                       Position              Beneficial Ownership         of Class
 ----------------                       --------              --------------------         --------
                                                                                 
Mike McFarland                 Chief Executive Officer,           6,800,000                  19.9%
71099, 198 - 8060 Silver       Chief Financial Officer,
Spring Blvd., Calgary,         President, Secretary,
Alberta  Canada                Treasurer and Director

Directors and Executive                                           6,800,000                  19.9%
 Officers as a Group


CHANGES IN CONTROL

We are unaware of any contract or other arrangement the operation of which may
at a subsequent date result in a change of control of our company.

ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR
         INDEPENDENCE

Except as described below, no director, executive officer, principal shareholder
holding at least 5% of our common shares, or any family member thereof, had any
material interest, direct or indirect, in any transaction, or proposed
transaction, since the beginning of our year ended September 30, 2011, or in any
currently proposed transaction, in which the amount involved in the transaction
exceeded or exceeds the lesser of $120,000 or one percent of the average of our
total assets at the year end for the last two completed fiscal years.

                                       37

As at September 30, 2011, the Company owed $35,000 (2010 - $nil) to the sole
director and officer of the Company. The balance relates to a loan advances
during the year and is unsecured, does not bear interest and is due on demand.

During the year ended September 30, 2010, $271,984 owing to the directors was
forgiven. The forgiveness of debt was treated as a capital transaction and
recorded as Additional Paid in Capital in the consolidated financial statements.

During the year ended September 30, 2010, 16,190,941 shares were returned to
treasury and cancelled for no consideration by two directors of the Company in
connection with their resignation.

During the year ended September 30, 2010, the Company sold its intellectual
property for proceeds of $1 to a former member of the Company's management. In
connection with this transaction, its obligation to issue shares with a value of
$99,737 was cancelled, and deferred compensation expense of $78,570, which was
included in shareholders' deficit, was reversed upon the cancellation of 150,000
performance-based escrow shares.

All related party transactions are conducted in the ordinary course of business
and measured at the exchange amount, which is the consideration established and
agreed to by the related parties.

CORPORATE GOVERNANCE

We currently have one director: Mike McFarland.

We have determined that Mr. McFarland is not an independent director, as that
term is used in Rule 4200(a)(15) of the Nasdaq Marketplace Rules and National
Instrument 52-110.

AUDIT COMMITTEE

Mike McFarland is the sole member of our audit committee. Mike McFarland is not
independent as defined by Rule 4200(a)(15) of the Nasdaq Marketplace Rules. Our
audit committee undertakes an independent review of our company's financial
statements, and meets with management to determine the adequacy of internal
controls and other financial reporting matters.

Our board of directors has determined that it does not have an audit committee
member that qualifies as an "audit committee financial expert" as defined in
Item 407(d)(5)(ii) of Regulation S-K. We believe that the audit committee
members are collectively capable of analyzing and evaluating our financial
statements and understanding internal controls and procedures for financial
reporting. In addition, we believe that retaining an independent director who
would qualify as an "audit committee financial expert" would be overly costly
and burdensome and is not warranted in our circumstances given the early stages
of our development and the fact that we have not generated revenues to date.

The audit committee acts in accordance with our Audit Committee Charter which
was filed as an exhibit to our Annual Report on Form 10-K, filed with the
Securities and Exchange Commission on December 22, 2008.

COMPENSATION COMMITTEE - COMPENSATION COMMITTEE INTERLOCKS AND INSIDER
PARTICIPATION

Mike McFarland is the sole member of our compensation committee. Our sole member
of the compensation committee is not independent as defined by Rule 4200(a)(15)
of the Nasdaq Marketplace Rules. The purpose of our compensation committee is to
oversee our company's compensation and benefit plans, including our compensation
and equity-based plans. Our compensation committee also monitors and evaluates
matters relating to the compensation and benefits structure of our company and
takes other such actions within the scope of the compensation committee charter
as our board of directors may assign to the compensation committee from time to
time.

The compensation committee acts in accordance with our Compensation Committee
Charter which was filed as an exhibit to our annual report on Form 10-K, filed
with the Securities and Exchange Commission on December 22, 2008.

                                       38

COMPENSATION COMMITTEE REPORT

The compensation committee has reviewed and discussed the Compensation
Discussion and Analysis with management, and based on the review and discussion,
the compensation committee recommended to the board of directors that the
Compensation Discussion and Analysis be included in our company's annual report.

TRANSACTIONS WITH INDEPENDENT DIRECTORS

None of our independent directors entered into any transaction, relationship or
arrangement during the year ended September 30, 2011 that was considered by our
board of directors in determining whether the director maintained his
independence in accordance with Rule 4200(a)(15) of the Nasdaq Marketplace
Rules.

ITEM 14. PRINCIPAL ACCOUNTANT FEES AND SERVICES

AUDIT FEES

The aggregate fees billed for the two most recently completed fiscal periods
ended September 30, 2011 and September 30, 2010 for professional services
rendered by Dale Matheson Carr-Hilton Labonte LLP, Chartered Accountants for the
audit of our annual consolidated financial statements, quarterly reviews of our
interim consolidated financial statements and services normally provided by the
independent accountant in connection with statutory and regulatory filings or
engagements for these fiscal periods were as follows:

                                                Year Ended          Year Ended
                                               September 30,       September 30,
                                                   2011                2010
                                                 --------            --------
Audit Fees and Audit Related Fees                $ 12.500            $ 20,000
Tax Fees                                           12,500                 Nil
All Other Fees                                        Nil                 Nil
                                                 --------            --------

Total                                            $ 25,000            $ 20,000
                                                 ========            ========

In the above table, "audit fees" are fees billed by our company's external
auditor for services provided in auditing our company's annual financial
statements for the subject year. "Audit-related fees" are fees not included in
audit fees that are billed by the auditor for assurance and related services
that are reasonably related to the performance of the audit review of our
company's financial statements. "Tax fees" are fees billed by the auditor for
professional services rendered for tax compliance, tax advice and tax planning.
"All other fees" are fees billed by the auditor for products and services not
included in the foregoing categories.

POLICY ON PRE-APPROVAL BY AUDIT COMMITTEE OF SERVICES PERFORMED BY INDEPENDENT
AUDITORS

The board of directors pre-approves all services provided by our independent
auditors. All of the above services and fees were reviewed and approved by the
board of directors either before or after the respective services were rendered.

The board of directors has considered the nature and amount of fees billed by
Dale Matheson Carr-Hilton Labonte LLP and believes that the provision of
services for activities unrelated to the audit is compatible with maintaining
Dale Matheson Carr-Hilton Labonte LLP.

                                       39

                                     PART IV

ITEM 15. EXHIBITS, FINANCIAL STATEMENT SCHEDULES

Exhibit
Number                             Description
------                             -----------

(2)      PLAN OF PURCHASE, SALE, REORGANIZATION, ARRANGEMENT, LIQUIDATION OR
         SUCCESSION

2.1      Share Exchange Agreement dated February 3, 2006, among our company,
         Upstream Canada, the shareholders of Upstream Canada and Steve Bajic
         (incorporated by reference from our Current Report on Form 8-K filed on
         February 6, 2006).

2.2      Amended and Restated Share Exchange Agreement dated February 24, 2006,
         among our company, Upstream Canada, the shareholders of Upstream Canada
         and Steve Bajic (incorporated by reference from our Current Report on
         Form 8-K filed on February 27, 2006).

(3)      ARTICLES OF INCORPORATION AND BY-LAWS

3.1      Articles of Incorporation (incorporated by reference from our
         Registration Statement on Form SB-2 filed on July 5, 2002).

3.2      Bylaws (incorporated by reference from our Registration Statement on
         Form SB-2 Filed on July 5, 2002). 3.3 Certificate of Amendment filed
         with the Nevada Secretary of State on March 8, 2005 (incorporated by
         reference from our Current Report on Form 8-K filed on March 10, 2005).

3.4      Certificate of Change filed with the Nevada Secretary of State on
         December 20, 2005 (incorporated by reference from our Current Report on
         Form 8-K filed on December 29, 2005).

3.5      Articles of Merger filed with the Nevada Secretary of State on February
         6, 2006 (incorporated by reference from our Current Report on Form 8-K
         filed on February 9, 2006).

3.6      Certificate of Amendment filed with the Nevada Secretary of State on
         November 27, 2006 (incorporated by reference from our Current Report on
         Form 8-K filed on November 30, 2006).

(10)     MATERIAL CONTRACTS

10.1     2007 Stock Option Plan (incorporated by reference from our Registration
         Statement on Form SB-2 filed on October 1, 2007)

10.2     Amendment to Employment Agreement dated August 18, 2009 between our
         company and Dexster Smith (incorporated by reference from our Quarterly
         Report on Form 10-Q filed on August 31, 2009)

10.3     Amendment to Employment Agreement dated August 18, 2009 between our
         company and Joel Bellenson (incorporated by reference from our
         Quarterly Report on Form 10-Q filed on August 31, 2009)

10.4     Return to Treasury Agreement dated December 14, 2009 between our
         company and Joel Bellenson (incorporated by reference from our Current
         Report on Form 8-K filed on December 14, 2009)

10.5     Return to Treasury Agreement dated December 14, 2009 between our
         company and Dexster Smith (incorporated by reference from our Current
         Report on Form 8-K filed on December 14, 2009)

10.6     Asset Sale Agreement dated December 14, 2009 between Pacific Pharma
         Technologies Inc. and JTAT Consulting Inc. (incorporated by reference
         from our Current Report on Form 8-K filed on December 14, 2009)

                                       40

(31)     SECTION 302 CERTIFICATIONS

31.1*    Certification of Principal Executive Officer and Principal Financial
         Officer filed pursuant to Section 302 of the Sarbanes-Oxley Act of
         2002.

(32)     SECTION 906 CERTIFICATIONS

32.1*    Certification of Principal Executive Officer pursuant to 18 U.S.C.
         Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley
         Act of 2002.

(99)     ADDITIONAL EXHIBITS

99.1     Compensation Committee Charter (incorporated by reference from our
         Annual Report on Form 10-K filed on December 19, 2008)

99.2     Audit Committee Charter (incorporated by reference from our Annual
         Report on Form 10-K filed on December 19, 2008)

101      Interactive data files pursuant to Rule 405 of Regulation S-T.

                                       41

                                   SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange
Act of 1934, the registrant has duly caused this report to be signed on its
behalf by the undersigned, thereunto duly authorized.

UPSTREAM BIOSCIENCES INC.


By: /s/ Mike Mcfarland
    ----------------------------------------
    Mike McFarland
    Chief Executive Officer, Chief Financial
    Officer, President, Secretary, Treasurer
    and Director
    (Principal Executive Officer, Principal
    Financial Officer and Principal
    Accounting Officer)
Date: January 13, 2012

Pursuant to the requirements of the Securities Exchange Act of 1934, this report
has been signed below by the following persons on behalf of the registrant and
in the capacities and on the dates indicated.


By: /s/ Mike Mcfarland
    ----------------------------------------
    Mike McFarland
    Chief Executive Officer, Chief Financial
    Officer, President, Secretary, Treasurer
    and Director
    (Principal Executive Officer, Principal
    Financial Officer and Principal
    Accounting Officer)
Date: January 13, 2012

                                       42