EXHIBIT 32.1 CERTIFICATION OF CHIEF EXECUTIVE OFFICER PURSUANT TO 18 U.S.C. SECTION 1350, AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 I, Jacob Ben Arie, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to my knowledge, Orgenesis Inc.'s Annual Report on Form 10-K for the fiscal year ended November 30, 2011 fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 and that information contained in such Annual Report on Form 10-K fairly presents in all material respects the financial condition and results of operations of Orgenesis Inc. Date: February 28, 2012 By: /s/ Jacob Ben Arie ------------------------------------- Jacob Ben Arie Title: Chief Executive Officer and President A signed original of this written statement required by Section 906 has been provided to Orgenesis Inc. and will be retained by Orgenesis Inc. and furnished to the Securities and Exchange Commission or its staff upon request.