UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 10-Q

(Mark One)
[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
    ACT OF 1934

                For the quarterly period ended December 31, 2012

[ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
    ACT OF 1934

           For the transition period from __________ to ____________

                        Commission file number 000-50331


                            UPSTREAM BIOSCIENCES INC.
             (Exact name of registrant as specified in its charter)

             Nevada                                              98-0371433
  (State or other jurisdiction                                (I.R.S. Employer
of incorporation or organization)                            Identification No.)

Three Sugar Creek Center, Suite 100, Sugar Land, TX                77478
    (Address of Principal Executive Offices)                     (Zip Code)

                                  713-929-3863
              (Registrant's telephone number, including area code)

                 50 West Liberty St., Suite 880, Reno, NV, 89501
              (Former name, former address and former fiscal year,
                          if changed since last report)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days. Yes [X] No [ ]

Indicate by check mark whether the registrant has submitted electronically and
posted on its corporate Web site, if any, every Interactive Data File required
to be submitted and posted pursuant to Rule 405 of Regulation S-T (ss.232.405 of
this chapter) during the preceding 12 months (or for such shorter period that
the registrant was required to submit and post such files). Yes [X] No [ ]

Indicate by check mark whether the registrant is a large accelerated filer, an
accelerated filer, a non-accelerated filer, or a smaller reporting company. See
definitions of "large accelerated filer," "accelerated filer," " and "smaller
reporting company" in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer [ ]                        Accelerated filer [ ]

Non-accelerated filer [ ]                          Smaller reporting company [X]
(Do not check if a smaller reporting company)

Indicate by check mark whether the registrant is a shell company (as defined in
Rule 12b-2 of the Exchange Act). Yes [ ] No [X]

                      APPLICABLE ONLY TO CORPORATE ISSUERS

Indicate the number of shares outstanding of each of the issuer's classes of
common stock, as of the latest practicable date:

1,975,645 common shares issued and outstanding as at February 14, 2013.

                         PART I - FINANCIAL INFORMATION

ITEM 1. FINANCIAL STATEMENTS.

Our unaudited interim financial statements are stated in United States dollars
and are prepared in accordance with United States generally accepted accounting
principles.

It is the opinion of management that the unaudited interim financial statements
for the quarter ended December 31, 2012 include all adjustments necessary in
order to ensure that the unaudited interim financial statements are not
misleading.

                                       2

                           Upstream Biosciences, Inc.
                         (A Development Stage Company)
                                 Balance Sheets





                                                                        December 31,          September 30,
                                                                           2012                   2012
                                                                       ------------           ------------
                                                                        (Unaudited)
                                                                                        
ASSETS

CURRENT ASSETS:
  Cash                                                                 $      1,065           $      4,312
  Prepaid expenses                                                            2,125                  3,500
                                                                       ------------           ------------
      Total Current Assets                                                    3,190                  7,812
                                                                       ------------           ------------

      Total Assets                                                     $      3,190           $      7,812
                                                                       ============           ============

LIABILITIES AND STOCKHOLDERS' DEFICIT

CURRENT LIABILITIES:
  Accounts payable and accrued liabilities                             $     28,348           $     24,576
  Advances from related parties                                              30,823                 10,000
                                                                       ------------           ------------
      Total Current Liabilities                                              59,171                 34,576
                                                                       ------------           ------------
STOCKHOLDERS' DEFICIT:
  Preferred stock: $0.001 par value; 100,000,000 shares authorized;
   none issued or outstanding                                                    --                     --
  Common stock: $0.001 par value; 100,000,000 shares authorized;
   1,974,630 shares issued and outstanding                                    1,975                  1,975
  Additional paid-in capital                                              7,190,770              7,190,770
  Deficit accumulated during the development stage                       (7,236,888)            (7,207,671)
  Accumulated other comprehensive income (loss):
    Foreign currency translation gain (loss)                                (11,838)               (11,838)
                                                                       ------------           ------------
      Total Stockholders' Deficit                                           (55,981)               (26,764)
                                                                       ------------           ------------

      Total Liabilities and Stockholders' Deficit                      $      3,190           $      7,812
                                                                       ============           ============



               See accompanying notes to the financial statements.

                                       3

                           Upstream Biosciences, Inc.
                         (A Development Stage Company)
                            Statements of Operations



                                                                                            For the Period from
                                                    For the                For the             June 14, 2004
                                                  Three Months           Three Months           (inception)
                                                     Ended                  Ended                 through
                                                  December 31,           December 31,           December 31,
                                                     2012                   2011                   2012
                                                 ------------           ------------           ------------
                                                  (Unaudited)            (Unaudited)            (Unaudited)
                                                                                      
Revenues                                         $         --           $         --           $     67,600
                                                 ------------           ------------           ------------
Operating expenses:
  Amortization                                             --                     --                133,600
  Consulting fees                                          --                     --                 12,598
  Investor and corporate communications                    --                     --                258,349
  License fees and royalties                               --                     --                114,384
  Management compensation                                  --                     --              1,526,086
  Research and development                                 --                     --              1,421,530
  Stock-based compensation                                 --                     --              2,090,632
  Loss on foreign exchange translations                    --                     --                 15,544
  Professional fees                                    10,649                  3,490                661,111
  General and administrative expenses                  18,568                  3,603                514,132
                                                 ------------           ------------           ------------
      Total operating expenses                         29,217                  7,093              6,747,966
                                                 ------------           ------------           ------------

Loss from operations                                  (29,217)                (7,093)            (6,680,366)

Other (income) expense:
  Asset impairment loss                                    --                     --                 59,010
  Compensation shares                                      --                     --                 25,000
  Interest and finance charges                             --                     --                598,965
  Interest income                                          --                     --                (84,671)
  Loss on sale of intellectual property                    --                     --                 78,570
  (Gain) loss on sale of subsidiary                        --                     --               (126,515)
  Other (income) expense                                   --                     --                (34,122)
                                                 ------------           ------------           ------------
      Total other (income) expense                         --                     --                516,237

Loss before income tax provision                      (29,217)                (7,093)            (7,196,603)

Income tax provision                                       --                     --                 57,415
                                                 ------------           ------------           ------------

Net loss                                         $    (29,217)          $     (7,093)          $ (7,139,188)
                                                 ============           ============           ============
Net loss per common share:
  - Basic and diluted                            $      (0.01)          $      (0.01)
                                                 ============           ============
Weighted average common shares outstanding:
 - Basic and diluted                                1,974,630                974,630
                                                 ============           ============



               See accompanying notes to the financial statements.

                                       4

                           Upstream Biosciences, Inc.
                         (A Development Stage Company)
                            Statements of Cash Flows



                                                                                                   For the Period from
                                                           For the                For the             June 14, 2004
                                                         Three Months           Three Months           (inception)
                                                            Ended                  Ended                 through
                                                         December 31,           December 31,           December 31,
                                                            2012                   2011                   2012
                                                        ------------           ------------           ------------
                                                         (Unaudited)            (Unaudited)            (Unaudited)
                                                                                             
Cash flows from operating activities:
  Net loss                                              $    (29,217)          $     (7,093)          $ (7,139,188)
  Adjustments to reconcile net loss to net cash
   used in operating activities:
     Amortization                                                 --                     --                133,600
     Accretion of convertible debenture                           --                     --                302,808
     Shares issued or to be issued for services                   --                     --              1,487,236
     Stock-based compensation                                     --                     --              1,658,590
     Compensation shares                                          --                     --                 25,000
     Deferred income tax                                          --                     --                (57,415)
     Asset impairment                                             --                     --                 59,010
     Gain on sale of subsidiary                                   --                     --               (126,515)
     Loss from sale of intellectual property                      --                     --                 78,570
  Changes in operating assets and liabilities:
     Prepaid expenses                                          1,375                    396                 (4,906)
     Other receivables                                            --                     --                (10,259)
     Accounts payable and accrued liabilities                  3,772                   (619)               259,755
     Due to related parties                                       --                     --                271,984
                                                        ------------           ------------           ------------
Net cash used in operating activities                        (24,070)                (7,316)            (3,061,730)
                                                        ------------           ------------           ------------
Cash flows from investing activities:
  Cash paid for acquisition of PPT shares                         --                     --                (51,507)
  Proceeds from the sale of subsidiary                            --                     --                      1
  Purchase of equipment                                           --                     --                (22,764)
                                                        ------------           ------------           ------------
Net cash used in investing activities                             --                     --                (74,270)
                                                        ------------           ------------           ------------
Cash flows from financing activities:
  Proceeds from issuance of convertible debentures                --                     --              1,000,000
  Proceeds from issuance of common shares, net                    --                     --              2,030,345
  Advances from (repayment made to) related party             20,823                     --                109,310
                                                        ------------           ------------           ------------
Net cash provided by financing activities                     20,823                     --              3,139,655
                                                        ------------           ------------           ------------

Effect of exchange rate changes on cash                           --                    207                 (2,590)
                                                        ------------           ------------           ------------

Net change in cash                                            (3,247)                (7,109)                 1,065

Cash at beginning of period                                    4,312                 12,602                     --
                                                        ------------           ------------           ------------

Cash at end of period                                   $      1,065           $      5,493           $      1,065
                                                        ============           ============           ============
Supplemental disclosure of cash flows information:
  Interest paid                                         $         --           $         --           $         --
                                                        ============           ============           ============
  Income tax paid                                       $         --           $         --           $         --
                                                        ============           ============           ============


               See accompanying notes to the financial statements.

                                       5

                           Upstream Biosciences, Inc.
                         (A Development Stage Company)
                           December 31, 2012 and 2011
                        Notes to the Financial Statements
                                   (Unaudited)

NOTE 1 - ORGANIZATION AND OPERATIONS

UPSTREAM BIOSCIENCES, INC.

Upstream  Biosciences,  Inc. ("the Company") was  incorporated on March 20, 2002
under  the laws of the  State of  Nevada.  The  Company  engages  in  developing
technology relating to biomarker identification, disease susceptibility and drug
response areas of cancer.

UPSTREAM BIOSCIENCES, INC., THE CANADIAN SUBSIDIARY

The Company acquired its wholly-owned Canadian subsidiary, Upstream Biosciences,
Inc.  ("Upstream  Canada") on February 24, 2006. This  transaction was accounted
for  as  a  recapitalization  transaction,  similar  to  a  reverse  acquisition
accounting,  with Upstream Canada being treated as the accounting  parent (legal
subsidiary)  and the Company being treated as the accounting  subsidiary  (legal
parent).

On February 15, 2011,  the Company sold  Upstream  Canada to a third party,  for
consideration of $1, realizing a gain on disposal of $126,515.

PACIFIC PHARMA TECHNOLOGIES, INC.

On December 14, 2009, The Company's  subsidiary,  Pacific  Pharma  Technologies,
Inc. ("PPT"), a British Columbia company,  entered into and closed an asset sale
agreement with JTAT  Consulting  Inc., a company  wholly-owned by Art Cherkasov.
Pursuant to the terms of the  agreement,  Pacific  Pharma sold all of the assets
held by Pacific Pharma to JTAT Consulting for the payment of $1.

The agreement resulted in the cancellation of the Company's  obligation to issue
shares with a value of $99,737, resulting in a loss on disposal of $78,570.

AMENDMENT TO THE ARTICLES OF INCORPORATION

Effective  December  4,  2012 the Board of  Directors  and the  majority  voting
stockholders  adopted  and  approved  a  resolution  to amend  its  Articles  of
Incorporation to effectuate a reverse split of all issued and outstanding shares
of common stock,  at a ratio of  one-for-thirty  five (1:35) (the "Reverse Stock
Split").

All shares and per share amounts in the financial  statements have been adjusted
to give retroactive effect to the Reverse Stock Split.

NOTE 2 - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

BASIS OF PRESENTATION

The accompanying  unaudited interim financial  statements and related notes have
been prepared in accordance with accounting principles generally accepted in the
United States of America ("U.S.  GAAP") for interim financial  information,  and
with the rules and  regulations  of the United  States  Securities  and Exchange
Commission  ("SEC") to Form 10-Q and Article 8 of Regulation  S-X.  Accordingly,
they do not include all of the information  and footnotes  required by U.S. GAAP
for complete financial  statements.  The unaudited interim financial  statements
furnished  reflect all  adjustments  (consisting of normal  recurring  accruals)
which are, in the opinion of  management,  necessary to a fair  statement of the
results for the interim periods  presented.  Interim results are not necessarily
indicative of the results for the full year. These financial  statements  should
be read in  conjunction  with the  financial  statements  of the Company for the
fiscal  year  ended  September  30,  2012 and  notes  thereto  contained  in the
Company's Annual Report on Form 10-K as filed with the SEC on December 31, 2012.

                                       6

RECLASSIFICATION

Certain amounts in the prior period financial  statements have been reclassified
to conform to the current period presentation.  These  reclassifications  had no
effect on reported income or losses.

DEVELOPMENT STAGE COMPANY

The Company is a development  stage  company as defined by section  915-10-20 of
the FASB  Accounting  Standards  Codification.  Although the Company  recognized
nominal  amount  of  revenues,  it is still  devoting  substantially  all of its
efforts on establishing the business and its planned  principal  operations have
not commenced.  All losses  accumulated  since inception have been considered as
part of the Company's development stage activities.

USE OF ESTIMATES AND ASSUMPTIONS

The preparation of financial statements in conformity with accounting principles
generally  accepted in the United States  requires  management to make estimates
and assumptions  that affect the reported  amounts of assets and liabilities and
disclosure of  contingent  assets and  liabilities  at the date of the financial
statements  as well as the reported  amount of revenues and expenses  during the
reporting period.

The Company's  significant  estimates and assumptions  include the fair value of
financial  instruments;  income tax rate,  income tax  provision  and  valuation
allowance of deferred tax assets;  and the assumption that the Company will be a
going concern.  Those significant  accounting  estimates or assumptions bear the
risk of change due to the fact that there are  uncertainties  attached  to those
estimates or assumptions,  and certain estimates or assumptions are difficult to
measure or value.

Management  bases  its  estimates  on  historical   experience  and  on  various
assumptions  that are believed to be  reasonable  under the  circumstances,  the
results of which form the basis for making  judgments  about the carrying values
of assets and liabilities that are not readily apparent from other sources.

Management   regularly  reviews  its  estimates  utilizing  currently  available
information,  changes  in facts and  circumstances,  historical  experience  and
reasonable  assumptions.  After such reviews,  and if deemed appropriate,  those
estimates are adjusted accordingly.

Actual results could differ from those estimates.

FAIR VALUE OF FINANCIAL INSTRUMENTS

The Company follows  paragraph  825-10-50-10  of the FASB  Accounting  Standards
Codification for disclosures  about fair value of its financial  instruments and
paragraph 820-10-35-37 of the FASB Accounting Standards Codification ("Paragraph
820-10-35-37") to measure the fair value of its financial instruments. Paragraph
820-10-35-37  establishes  a framework  for  measuring  fair value in  generally
accepted accounting  principles (GAAP), and expands disclosures about fair value
measurements.   To  increase   consistency  and   comparability  in  fair  value
measurements and related disclosures,  Paragraph 820-10-35-37 establishes a fair
value  hierarchy which  prioritizes  the inputs to valuation  techniques used to
measure fair value into three (3) broad levels.  The fair value  hierarchy gives
the  highest  priority  to quoted  prices  (unadjusted)  in active  markets  for
identical assets or liabilities and the lowest priority to unobservable  inputs.
The three (3) levels of fair value hierarchy  defined by Paragraph  820-10-35-37
are described below:

Level 1  Quoted market prices  available in active markets for identical  assets
         or liabilities as of the reporting date.

Level 2  Pricing inputs other than quoted prices in active  markets  included in
         Level 1, which are either  directly or indirectly  observable as of the
         reporting date.

                                       7

Level 3  Pricing   inputs  that  are   generally   observable   inputs  and  not
         corroborated by market data.

Financial  assets are  considered  Level 3 when their fair values are determined
using pricing models,  discounted cash flow  methodologies or similar techniques
and at least one significant model assumption or input is unobservable.

The  fair  value  hierarchy   gives  the  highest   priority  to  quoted  prices
(unadjusted)  in active  markets for  identical  assets or  liabilities  and the
lowest  priority  to  unobservable  inputs.  If the inputs  used to measure  the
financial  assets and  liabilities  fall  within  more than one level  described
above, the categorization is based on the lowest level input that is significant
to the fair value measurement of the instrument.

The carrying amounts of the Company's financial assets and liabilities,  such as
cash, prepaid expenses and accounts payable and accrued liabilities, approximate
their fair values because of the short maturity of these instruments.

Transactions  involving  related parties cannot be presumed to be carried out on
an arm's-length basis, as the requisite  conditions of competitive,  free-market
dealings may not exist. Representations about transactions with related parties,
if made, shall not imply that the related party transactions were consummated on
terms equivalent to those that prevail in arm's-length  transactions unless such
representations can be substantiated.

It is not,  however,  practical  to  determine  the fair value of advances  from
stockholder, if any, due to their related party nature.

FISCAL YEAR-END

The Company elected September 30 as its fiscal year-end date.

CASH EQUIVALENTS

The Company  considers all highly liquid  investments  with  maturities of three
months or less at the time of purchase to be cash equivalents.

RELATED PARTIES

The  Company  follows   subtopic   850-10  of  the  FASB  Accounting   Standards
Codification for the identification of related parties and disclosure of related
party transactions.

Pursuant to Section  850-10-20 the related  parties include a. affiliates of the
Company;  b. entities for which  investments in their equity securities would be
required,  absent the  election  of the fair value  option  under the Fair Value
Option Subsection of Section 825-10-15, to be accounted for by the equity method
by the investing entity; c. trusts for the benefit of employees, such as pension
and  profit-sharing  trusts  that are  managed  by or under the  trusteeship  of
management; d. principal owners of the Company; e. management of the Company; f.
other  parties  with which the  Company  may deal if one party  controls  or can
significantly  influence the management or operating policies of the other to an
extent  that one of the  transacting  parties  might  be  prevented  from  fully
pursuing its own separate interests; and g. other parties that can significantly
influence the  management or operating  policies of the  transacting  parties or
that  have an  ownership  interest  in one of the  transacting  parties  and can
significantly  influence  the  other  to an  extent  that  one  or  more  of the
transacting  parties  might be  prevented  from fully  pursuing its own separate
interests.

The financial  statements  shall include  disclosures of material  related party
transactions,  other than compensation  arrangements,  expense  allowances,  and
other similar items in the ordinary course of business.  However,  disclosure of
transactions  that are eliminated in the preparation of consolidated or combined
financial statements is not required in those statements.  The disclosures shall
include: a. the nature of the relationship(s)  involved; b. a description of the
transactions, including transactions to which no amounts or nominal amounts were
ascribed, for each of the periods for which income statements are presented, and
such other  information  deemed  necessary to an understanding of the effects of

                                       8

the  transactions  on  the  financial  statements;  c.  the  dollar  amounts  of
transactions  for each of the periods for which income  statements are presented
and the effects of any change in the method of establishing  the terms from that
used in the preceding  period;  and d. amounts due from or to related parties as
of the date of each balance sheet presented and, if not otherwise apparent,  the
terms and manner of settlement.

COMMITMENT AND CONTINGENCIES

The  Company  follows   subtopic   450-20  of  the  FASB  Accounting   Standards
Codification  to report  accounting for  contingencies.  Certain  conditions may
exist as of the date the financial  statements are issued, which may result in a
loss to the  Company  but which will only be  resolved  when one or more  future
events occur or fail to occur. The Company assesses such contingent liabilities,
and such assessment  inherently  involves an exercise of judgment.  In assessing
loss  contingencies  related to legal  proceedings  that are pending against the
Company or unasserted  claims that may result in such  proceedings,  the Company
evaluates the perceived merits of any legal  proceedings or unasserted claims as
well as the  perceived  merits of the amount of relief  sought or expected to be
sought therein.

If the assessment of a contingency indicates that it is probable that a material
loss has been incurred and the amount of the  liability  can be estimated,  then
the estimated liability would be accrued in the Company's financial  statements.
If the assessment  indicates that a potential  material loss  contingency is not
probable but is  reasonably  possible,  or is probable but cannot be  estimated,
then the nature of the  contingent  liability,  and an  estimate of the range of
possible losses, if determinable and material, would be disclosed.

Loss  contingencies  considered  remote are generally not disclosed  unless they
involve guarantees, in which case the guarantees would be disclosed.  Management
does not believe,  based upon  information  available  at this time,  that these
matters will have a material adverse effect on the Company's financial position,
results of operations or cash flows.  However,  there is no assurance  that such
matters  will not  materially  and  adversely  affect  the  Company's  business,
financial position, and results of operations or cash flows.

REVENUE RECOGNITION

The Company follows  paragraph  605-10-S99-1  of the FASB  Accounting  Standards
Codification for revenue recognition.  The Company recognizes revenue when it is
realized or realizable and earned.  The Company  considers  revenue  realized or
realizable and earned when all of the following criteria are met: (i) persuasive
evidence of an  arrangement  exists,  (ii) the  product has been  shipped or the
services have been  rendered to the customer,  (iii) the sales price is fixed or
determinable, and (iv) collectability is reasonably assured.

FOREIGN CURRENCY TRANSACTIONS

The Company  applies the guidelines as set out in Section  830-20-35 of the FASB
Accounting  Standards  Codification  ("Section  830-20-35") for foreign currency
transactions.  Pursuant to Section  830-20-35 of the FASB  Accounting  Standards
Codification,  foreign currency  transactions  are  transactions  denominated in
currencies other than U.S. Dollar, the Company's  reporting currency or Canadian
dollar,  the  Company's  Canadian  subsidiaries'  functional  currency.  Foreign
currency  transactions  may produce  receivables  or payables  that are fixed in
terms of the amount of foreign  currency that will be received or paid. A change
in exchange  rates between the  functional  currency and the currency in which a
transaction  is  denominated  increases  or  decreases  the  expected  amount of
functional currency cash flows upon settlement of the transaction. That increase
or decrease in expected  functional  currency  cash flows is a foreign  currency
transaction  gain or loss that generally  shall be included in  determining  net
income  for  the  period  in  which  the  exchange  rate  changes.  Likewise,  a
transaction  gain or loss (measured from the transaction date or the most recent
intervening balance sheet date,  whichever is later) realized upon settlement of
a foreign  currency  transaction  generally shall be included in determining net
income for the period in which the  transaction  is settled.  The  exceptions to
this  requirement  for inclusion in net income of  transaction  gains and losses
pertain  to  certain  intercompany  transactions  and to  transactions  that are

                                       9

designated as, and effective as,  economic hedges of net investments and foreign
currency  commitments.  Pursuant  to Section  830-20-25  of the FASB  Accounting
Standards  Codification,  the  following  shall  apply to all  foreign  currency
transactions of an enterprise and its investees: (a) at the date the transaction
is recognized,  each asset, liability,  revenue,  expense, gain, or loss arising
from the transaction  shall be measured and recorded in the functional  currency
of the  recording  entity by use of the exchange  rate in effect at that date as
defined in section 830-10-20 of the FASB Accounting Standards Codification;  and
(b) at each  balance  sheet date,  recorded  balances  that are  denominated  in
currencies  other than the  functional  currency  or  reporting  currency of the
recording entity shall be adjusted to reflect the current exchange rate.

STOCK-BASED COMPENSATION FOR OBTAINING EMPLOYEE SERVICES

The  Company  accounts  for its stock  based  compensation  in which the Company
obtains  employee  services  in  share-based  payment   transactions  under  the
recognition and measurement  principles of the fair value recognition provisions
of section 718-10-30 of the FASB Accounting Standards Codification.  Pursuant to
paragraph  718-10-30-6  of  the  FASB  Accounting  Standards  Codification,  all
transactions in which goods or services are the  consideration  received for the
issuance of equity  instruments are accounted for based on the fair value of the
consideration  received  or the fair  value  of the  equity  instrument  issued,
whichever is more reliably  measurable.  The measurement  date used to determine
the fair value of the  equity  instrument  issued is the  earlier of the date on
which the  performance  is  complete  or the date on which it is  probable  that
performance will occur.

The fair value of options and similar  instruments  is  estimated on the date of
grant  using a  Black-Scholes  option-pricing  valuation  model.  The  ranges of
assumptions for inputs are as follows:

*    Expected term of share options and similar  instruments:  The expected life
     of options and similar instruments represents the period of time the option
     and/or  warrant are  expected  to be  outstanding.  Pursuant  to  Paragraph
     718-10-50-2(f)(2)(i)  of the FASB  Accounting  Standards  Codification  the
     expected  term of share  options and  similar  instruments  represents  the
     period of time the  options  and  similar  instruments  are  expected to be
     outstanding  taking  into  consideration  of the  contractual  term  of the
     instruments and employees'  expected  exercise and post-vesting  employment
     termination  behavior  into the fair  value  (or  calculated  value) of the
     instruments.  Pursuant to paragraph 718-10-S99-1,  it may be appropriate to
     use the SIMPLIFIED METHOD,  I.E., EXPECTED TERM = ((VESTING TERM + ORIGINAL
     CONTRACTUAL  TERM)  / 2),  if  (i)  A  company  does  not  have  sufficient
     historical  exercise  data to  provide a  reasonable  basis  upon  which to
     estimate  expected term due to the limited period of time its equity shares
     have been publicly traded; (ii) A company  significantly  changes the terms
     of its share  option  grants or the types of employees  that receive  share
     option grants such that its historical  exercise data may no longer provide
     a reasonable basis upon which to estimate expected term; or (iii) A company
     has or expects to have significant  structural changes in its business such
     that its historical  exercise data may no longer provide a reasonable basis
     upon which to  estimate  expected  term.  The Company  uses the  simplified
     method to calculate expected term of share options and similar  instruments
     as the company does not have sufficient historical exercise data to provide
     a reasonable basis upon which to estimate expected term.

*    Expected  volatility of the entity's shares and the method used to estimate
     it.  Pursuant to ASC Paragraph  718-10-50-2(f)(2)(ii)  a  thinly-traded  or
     nonpublic  entity that uses the calculated  value method shall disclose the
     reasons why it is not  practicable for the Company to estimate the expected
     volatility of its share price,  the appropriate  industry sector index that
     it has selected,  the reasons for selecting that particular  index, and how
     it has calculated  historical volatility using that index. The Company uses
     the average  historical  volatility of the  comparable  companies  over the
     expected  contractual  life of the share options or similar  instruments as
     its expected  volatility.  If shares of a company are thinly traded the use
     of weekly or monthly price observations would generally be more appropriate
     than the use of daily  price  observations  as the  volatility  calculation
     using daily observations for such shares could be artificially inflated due
     to a larger spread  between the bid and asked quotes and lack of consistent
     trading in the market.

                                       10

*    Expected annual rate of quarterly  dividends.  An entity that uses a method
     that employs  different  dividend rates during the  contractual  term shall
     disclose  the range of  expected  dividends  used and the  weighted-average
     expected  dividends.  The expected dividend yield is based on the Company's
     current dividend yield as the best estimate of projected dividend yield for
     periods  within the  expected  contractual  life of the option and  similar
     instruments.

*    Risk-free  rate(s).  An entity  that uses a method that  employs  different
     risk-free  rates shall  disclose  the range of  risk-free  rates used.  The
     risk-free interest rate is based on the U.S. Treasury yield curve in effect
     at the time of grant for periods within the contractual  life of the option
     and similar instruments.

The  Company's  policy is to  recognize  compensation  cost for awards with only
service  conditions and a graded vesting schedule on a straight-line  basis over
the requisite service period for the entire award.

EQUITY INSTRUMENTS ISSUED TO PARTIES OTHER THAN EMPLOYEES FOR ACQUIRING GOODS OR
SERVICES

The  Company  accounts  for  equity  instruments  issued to  parties  other than
employees for acquiring goods or services under guidance of Sub-topic  505-50 of
the FASB Accounting Standards Codification ("Sub-topic 505-50").

Pursuant to ASC Section  505-50-30,  all transactions in which goods or services
are the  consideration  received  for the  issuance  of equity  instruments  are
accounted for based on the fair value of the consideration  received or the fair
value of the equity instrument  issued,  whichever is more reliably  measurable.
The measurement  date used to determine the fair value of the equity  instrument
issued is the  earlier of the date on which the  performance  is complete or the
date on which it is probable that performance will occur.

The fair  value of option or  warrant  award is  estimated  on the date of grant
using a Black-Scholes  option-pricing valuation model. The ranges of assumptions
for inputs are as follows:

*    Expected  term of  share  options  and  similar  instruments:  Pursuant  to
     Paragraph  718-10-50-2 of the FASB Accounting  Standards  Codification  the
     expected  term of share  options and  similar  instruments  represents  the
     period of time the  options  and  similar  instruments  are  expected to be
     outstanding  taking  into  consideration  of the  contractual  term  of the
     instruments and holder's expected exercise behavior into the fair value (or
     calculated  value) of the instruments.  The Company uses historical data to
     estimate holder's expected exercise behavior. The contractual term of share
     options or similar instruments is used as expected term of share options or
     similar instruments for the Company if it is a newly formed corporation.

*    Expected  volatility of the entity's shares and the method used to estimate
     it. An entity that uses a method that employs different volatilities during
     the contractual term shall disclose the range of expected volatilities used
     and the weighted-average  expected volatility. A thinly-traded or nonpublic
     entity that uses the calculated value method shall disclose the reasons why
     it is not practicable  for the Company to estimate the expected  volatility
     of its share  price,  the  appropriate  industry  sector  index that it has
     selected,  the reasons for selecting that particular  index, and how it has
     calculated  historical  volatility  using that index.  The Company uses the
     average historical volatility of the comparable companies over the expected
     contractual  life  of the  share  options  or  similar  instruments  as its
     expected  volatility.  If shares of a company are thinly  traded the use of
     weekly or monthly price  observations  would generally be more  appropriate
     than the use of daily  price  observations  as the  volatility  calculation
     using daily observations for such shares could be artificially inflated due
     to a larger spread  between the bid and asked quotes and lack of consistent
     trading in the market.

*    Expected annual rate of quarterly  dividends.  An entity that uses a method
     that employs  different  dividend rates during the  contractual  term shall
     disclose  the range of  expected  dividends  used and the  weighted-average
     expected  dividends.  The expected dividend yield is based on the Company's
     current dividend yield as the best estimate of projected dividend yield for
     periods  within the  expected  contractual  life of the option and  similar
     instruments.

                                       11

*    Risk-free  rate(s).  An entity  that uses a method that  employs  different
     risk-free  rates shall  disclose  the range of  risk-free  rates used.  The
     risk-free interest rate is based on the U.S. Treasury yield curve in effect
     at the time of grant for periods within the contractual  life of the option
     and similar instruments.

Pursuant to ASC paragraph 505-50-25-7,  if fully vested,  non-forfeitable equity
instruments  are  issued  at the date the  grantor  and  grantee  enter  into an
agreement  for goods or services  (no  specific  performance  is required by the
grantee to retain those equity instruments), then, because of the elimination of
any obligation on the part of the counterparty to earn the equity instruments, a
measurement  date has  been  reached.  A  grantor  shall  recognize  the  equity
instruments  when they are issued (in most cases,  when the agreement is entered
into). Whether the corresponding cost is an immediate expense or a prepaid asset
(or  whether  the  debit  should be  characterized  as  contra-equity  under the
requirements  of  paragraph  505-50-45-1)  depends  on the  specific  facts  and
circumstances.  Pursuant to ASC  paragraph  505-50-45-1,  a grantor may conclude
that an asset (other than a note or a  receivable)  has been  received in return
for fully vested, non-forfeitable equity instruments that are issued at the date
the grantor and grantee  enter into an agreement  for goods or services  (and no
specific  performance is required by the grantee in order to retain those equity
instruments).  Such an asset  shall not be  displayed  as  contra-equity  by the
grantor of the equity instruments.  The transferability (or lack thereof) of the
equity instruments shall not affect the balance sheet display of the asset. This
guidance is limited to transactions in which equity  instruments are transferred
to other than  employees in exchange for goods or  services.  Section  505-50-30
provides  guidance on the determination of the measurement date for transactions
that are within the scope of this Subtopic.

Pursuant to Paragraphs  505-50-25-8  and  505-50-25-9,an  entity may grant fully
vested,  non-forfeitable  equity instruments that are exercisable by the grantee
only after a specified period of time if the terms of the agreement  provide for
earlier exercisability if the grantee achieves specified performance conditions.
Any measured cost of the  transaction  shall be recognized in the same period(s)
and in the same  manner as if the entity had paid cash for the goods or services
or used cash rebates as a sales discount  instead of paying with, or using,  the
equity instruments.  A recognized asset, expense, or sales discount shall not be
reversed  if a stock  option  that the  counterparty  has the right to  exercise
expires unexercised.

Pursuant to ASC paragraph  505-50-30-S99-1,  if the Company  receives a right to
receive   future   services  in  exchange  for  unvested,   forfeitable   equity
instruments,  those equity  instruments  are treated as unissued for  accounting
purposes until the future  services are received (that is, the  instruments  are
not  considered  issued  until  they  vest).  Consequently,  there  would  be no
recognition at the measurement date and no entry should be recorded.

INCOME TAX PROVISION

The Company  accounts  for income  taxes  under  Section  740-10-30  of the FASB
Accounting  Standards  Codification.  Deferred income tax assets and liabilities
are determined  based upon differences  between the financial  reporting and tax
bases of assets and liabilities and are measured using the enacted tax rates and
laws  that will be in effect  when the  differences  are  expected  to  reverse.
Deferred  tax  assets  are  reduced  by a  valuation  allowance  to  the  extent
management  concludes  it is more  likely  than not that the assets  will not be
realized.  Deferred tax assets and  liabilities  are measured  using enacted tax
rates expected to apply to taxable income in the years in which those  temporary
differences are expected to be recovered or settled.  The effect on deferred tax
assets and  liabilities of a change in tax rates is recognized in the statements
of operations in the period that includes the enactment date.

The  Company  adopted  section  740-10-25  of  the  FASB  Accounting   Standards
Codification   ("Section   740-10-25").    Section   740-10-25   addresses   the
determination of whether tax benefits claimed or expected to be claimed on a tax
return should be recorded in the financial statements.  Under Section 740-10-25,
the Company may recognize the tax benefit from an uncertain tax position only if
it is  more  likely  than  not  that  the tax  position  will  be  sustained  on
examination  by the taxing  authorities,  based on the  technical  merits of the
position.  The tax benefits  recognized in the financial  statements from such a

                                       12

position should be measured based on the largest benefit that has a greater than
fifty percent  (50%)  likelihood  of being  realized  upon ultimate  settlement.
Section  740-10-25  also provides  guidance on  de-recognition,  classification,
interest  and  penalties  on income  taxes,  accounting  in interim  periods and
requires increased disclosures.

The estimated future tax effects of temporary  differences between the tax basis
of assets and liabilities are reported in the  accompanying  balance sheets,  as
well as tax credit  carry-backs  and  carry-forwards.  The Company  periodically
reviews the recoverability of deferred tax assets recorded on its balance sheets
and provides valuation allowances as management deems necessary.

Management makes judgments as to the  interpretation  of the tax laws that might
be  challenged  upon an audit and cause  changes to  previous  estimates  of tax
liability.   In  addition,   the  Company   operates   within   multiple  taxing
jurisdictions  and is subject to audit in these  jurisdictions.  In management's
opinion,  adequate  provisions for income taxes have been made for all years. If
actual  taxable income by tax  jurisdiction  varies from  estimates,  additional
allowances or reversals of reserves may be necessary.

UNCERTAIN TAX POSITIONS

The Company did not take any uncertain tax positions and had no  adjustments  to
its income tax  liabilities  or benefits  pursuant to the  provisions of Section
740-10-25 for the interim period ended December 31, 2012 or 2011.

NET INCOME (LOSS) PER COMMON SHARE

Net income (loss) per common share is computed  pursuant to Section 260-10-45 of
the FASB Accounting Standards  Codification.  Basic net income (loss) per common
share is computed by dividing net income (loss) by the weighted  average  number
of shares of common  stock  outstanding  during the  period.  Diluted net income
(loss)  per common  share is  computed  by  dividing  net  income  (loss) by the
weighted  average  number of shares of  common  stock and  potentially  dilutive
outstanding  shares of common stock  during the period to reflect the  potential
dilution that could occur from common shares issuable  through  contingent share
arrangements, stock options and warrants.

There were no potentially  dilutive  common shares  outstanding  for the interim
period ended December 31, 2012 or 2011.

CASH FLOWS REPORTING

The Company adopted  paragraph  230-10-45-24  of the FASB  Accounting  Standards
Codification  for cash flows  reporting,  classifies  cash receipts and payments
according  to  whether  they  stem  from  operating,   investing,  or  financing
activities and provides  definitions of each category,  and uses the indirect or
reconciliation  method ("Indirect method") as defined by paragraph  230-10-45-25
of the FASB  Accounting  Standards  Codification  to  report  net cash flow from
operating  activities  by adjusting  net income to reconcile it to net cash flow
from  operating  activities by removing the effects of (a) all deferrals of past
operating  cash  receipts  and  payments  and all  accruals of  expected  future
operating  cash receipts and payments and (b) all items that are included in net
income that do not affect  operating  cash  receipts and  payments.  The Company
reports the reporting currency  equivalent of foreign currency cash flows, using
the  current  exchange  rate at the time of the cash  flows  and the  effect  of
exchange  rate  changes  on cash held in foreign  currencies  is  reported  as a
separate item in the reconciliation of beginning and ending balances of cash and
cash  equivalents  and  separately  provides  information  about  investing  and
financing  activities  not  resulting in cash receipts or payments in the period
pursuant  to   paragraph   830-230-45-1   of  the  FASB   Accounting   Standards
Codification.

SUBSEQUENT EVENTS

The Company  follows the guidance in Section  855-10-50  of the FASB  Accounting
Standards Codification for the disclosure of subsequent events. The Company will
evaluate  subsequent events through the date when the financial  statements were
issued.  Pursuant to ASU 2010-09 of the FASB Accounting Standards  Codification,
the Company as an SEC filer considers its financial  statements issued when they
are widely distributed to users, such as through filing them on EDGAR.

                                       13

RECENTLY ISSUED ACCOUNTING PRONOUNCEMENTS

FASB ACCOUNTING STANDARDS UPDATE NO. 2011-08

In September  2011,  the FASB issued the FASB  Accounting  Standards  Update No.
2011-08 "INTANGIBLES--GOODWILL AND OTHER: TESTING GOODWILL FOR IMPAIRMENT" ("ASU
2011-08").  This Update is to simplify how public and  nonpublic  entities  test
goodwill  for  impairment.  The  amendments  permit an  entity  to first  assess
qualitative  factors to  determine  whether it is more  likely than not that the
fair value of a reporting  unit is less than its carrying  amount as a basis for
determining  whether it is necessary to perform the two-step goodwill impairment
test described in Topic 350.  Under the amendments in this Update,  an entity is
not required to calculate  the fair value of a reporting  unit unless the entity
determines  that it is more likely than not that its fair value is less than its
carrying amount.

The guidance is effective for interim and annual  periods  beginning on or after
December 15, 2011. Early adoption is permitted.

FASB ACCOUNTING STANDARDS UPDATE NO. 2011-11

In December  2011,  the FASB  issued the FASB  Accounting  Standards  Update No.
2011-11 "BALANCE SHEET:  DISCLOSURES  ABOUT  OFFSETTING  ASSETS AND LIABILITIES"
("ASU 2011-11").  This Update requires an entity to disclose  information  about
offsetting and related  arrangements to enable users of its financial statements
to understand the effect of those  arrangements on its financial  position.  The
objective of this disclosure is to facilitate  comparison between those entities
that prepare  their  financial  statements  on the basis of U.S.  GAAP and those
entities that prepare their financial statements on the basis of IFRS.

The amended guidance is effective for annual reporting  periods  beginning on or
after January 1, 2013, and interim periods within those annual periods.

FASB ACCOUNTING STANDARDS UPDATE NO. 2012-02

In July 2012, the FASB issued the FASB Accounting  Standards  Update No. 2012-02
"INTANGIBLES--GOODWILL AND OTHER (TOPIC 350) TESTING INDEFINITE-LIVED INTANGIBLE
ASSETS FOR IMPAIRMENT" ("ASU 2012-02").

This  Update  is  intended  to  reduce  the  cost  and   complexity  of  testing
indefinite-lived  intangible  assets other than  goodwill for  impairment.  This
guidance builds upon the guidance in ASU 2011-08,  entitled TESTING GOODWILL FOR
IMPAIRMENT.  ASU 2011-08 was issued on  September  15, 2011,  and feedback  from
stakeholders  during the  exposure  period  related to the  goodwill  impairment
testing  guidance  was that the  guidance  also would be  helpful in  impairment
testing for intangible assets other than goodwill.

The revised  standard allows an entity the option to first assess  qualitatively
whether  it is more  likely  than not  (that  is, a  likelihood  of more than 50
percent)  that  an   indefinite-lived   intangible   asset  is  impaired,   thus
necessitating that it perform the quantitative impairment test. An entity is not
required to calculate the fair value of an indefinite-lived intangible asset and
perform the quantitative impairment test unless the entity determines that it is
more likely than not that the asset is impaired.

This Update is effective for annual and interim  impairment  tests  performed in
fiscal years  beginning  after  September 15, 2012.  Earlier  implementation  is
permitted.

OTHER RECENTLY ISSUED, BUT NOT YET EFFECTIVE ACCOUNTING PRONOUNCEMENTS

Management  does  not  believe  that  any  other  recently  issued,  but not yet
effective accounting pronouncements, if adopted, would have a material effect on
the accompanying financial statements.

                                       14

NOTE 3 - GOING CONCERN

The  accompanying  financial  statements  have been  prepared  assuming that the
Company will  continue as a going  concern,  which  contemplates  continuity  of
operations,  realization of assets, and liquidation of liabilities in the normal
course of business.

As reflected in the accompanying financial statements, the Company had a deficit
accumulated  during the  development  stage at December 31, 2012, a net loss and
net cash  used in  operating  activities  for the  interim  period  then  ended,
respectively.  These factors raise substantial doubt about the Company's ability
to continue as a going concern.

While the Company is attempting to commence  operations and generate  sufficient
revenues,  the Company's  cash position may not be sufficient  enough to support
the Company's daily operations.  Management intends to raise additional funds by
way of a private  or  public  offering.  Management  believes  that the  actions
presently  being  taken to further  implement  its  business  plan and  generate
sufficient  revenues  provide the  opportunity  for the Company to continue as a
going  concern.  While the Company  believes in the viability of its strategy to
generate sufficient revenues and in its ability to raise additional funds, there
can be no assurances to that effect. The ability of the Company to continue as a
going concern is dependent upon the Company's  ability to further  implement its
business plan and generate sufficient revenues.

The  financial  statements  do  not  include  any  adjustments  related  to  the
recoverability  and  classification of recorded asset amounts or the amounts and
classification  of  liabilities  that might be  necessary  should the Company be
unable to continue as a going concern.

NOTE 4 - RELATED PARTY TRANSACTIONS

ADVANCES FROM SOLE DIRECTOR AND OFFICER

From time to time,  the sole director and officer of the Company  advances funds
to the  Company for working  capital  purpose.  Those  advances  are  unsecured,
non-interest bearing and due on demand.

At December 31, 2012 the Company  owed $30,823 to the sole  director and officer
of the  Company.  The  balance  relates  to  advances  during  the  year  and is
unsecured, does not bear interest and is due on demand.

NOTE 5 - STOCKHOLDERS' EQUITY (DEFICIT)

SHARES AUTHORIZED

Upon  formation  the total  number of shares of all  classes of stock  which the
Company is authorized to issue is Two Hundred  Million  (200,000,000)  shares of
which One Hundred Million  (100,000,000)  shares shall be Preferred  Stock,  par
value $0.001 per share,  and One Hundred Million  (100,000,000)  shares shall be
Common Stock, par value $0.001 per share.

Effective  December 4, 2012,  the Board of  Directors  and the  majority  voting
stockholders  adopted  and  approved  a  resolution  to amend  its  Articles  of
Incorporation to effectuate a reverse split of all issued and outstanding shares
of common stock,  at a ratio of  one-for-thirty  five (1:35) (the "Reverse Stock
Split").

All shares and per share amounts in the financial  statements have been adjusted
to give retroactive effect to the Stock Split.

                                       15

COMMON STOCK

On July 23, 2012, the Company issued 1,000,000 shares of common stock, at $0.035
per share for gross proceeds of $35,000.

STOCK OPTIONS

The Company has a stock option plan (the "Plan")  authorizing the issuance of up
to  5,000,000  shares of its common stock upon  exercise of the options  granted
pursuant  to the Plan.  Under  the Plan,  the  Company's  employees,  directors,
officers,  consultants  and advisors  (collectively  the  "Optionee  Group") are
eligible to receive a grant of the Company's options, provided however that bona
fide services are rendered by  consultants or advisors and such services are not
in  connection  with  the  offer  or sale  of  securities  in a  capital-raising
transaction.

During the interim period ended December 31, 2012, the Company did not grant any
stock options.

NOTE 6 - SUBSEQUENT EVENTS

The Company  has  evaluated  all events that occur after the balance  sheet date
through the date when the financial  statements were issued to determine if they
must be reported.  The Management of the Company  determined  that there were no
reportable subsequent events to be disclosed.

                                       16

ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATIONS.

FORWARD-LOOKING STATEMENTS

This quarterly report contains forward-looking statements that involve risk,
uncertainties and assumptions. In some cases, you can identify forward-looking
statements by terminology such as "may", "should", "expect", "plan",
"anticipate", "believe", "estimate", "predict", "potential" or "continue" or the
negative of these terms or other comparable terminology. Examples of
forward-looking statements made in this quarterly report on Form 10-Q include
statements about:

     *    Our business plans,

     *    Our ability to raise additional finances, and

     *    Our future investments and allocation of capital resources.

These statements are only predictions and involve known and unknown risks,
uncertainties and other factors, including:

     *    General economic and business conditions,

     *    Our lack of operating history,

     *    Our financial condition,

     *    Our material weakness in our internal control over financial
          reporting,

     *    Our patents are only a provisional patent, and

     *    The risks in the section of this annual report entitled "Risk
          Factors",

any of which may cause our or our industry's actual results, levels of activity,
performance or achievements to be materially different from any future results,
levels of activity, performance or achievements expressed or implied by these
forward-looking statements.

While these forward-looking statements and any assumptions upon which they are
based are made in good faith and reflect our current judgment regarding the
direction of our business, actual results will almost always vary, sometimes
materially, from any estimates, predictions, projections, assumptions or other
future performance suggested herein. Except as required by applicable law,
including the securities laws of the United States, we do not intend to update
any of the forward-looking statements to conform these statements to actual
results.

Our unaudited interim financial statements are stated in United States dollars
and are prepared in accordance with United States generally accepted accounting
principles. The following discussion should be read in conjunction with our
unaudited interim financial statements and the related notes that appear
elsewhere in this quarterly report.

In this quarterly report, unless otherwise specified, all references to "common
shares" refer to the common shares in our capital stock and the terms "we", "us"
and "our" mean Upstream Biosciences Inc..

                                       17

RESULTS OF OPERATIONS FOR THE THREE MONTHS ENDED DECEMBER 31, 2012

REVENUE

We are a development stage company and have not generated any significant
revenues from our technologies since inception and $nil during the current
period. We anticipate significant additional time and financing will be required
before our technologies are developed to a marketable state.

EXPENSES

Our operating expenses for the three month period ended December 31, 2012 were
$29,217 compared to $7,093 in 2011. This net increase of $22,124 was primarily
due to the following:

     -    $7,159 increase in professional fees, which comprise legal and
          accounting fees, due to the special meeting held by the company during
          the period;

     -    14,965 increase in general and administrative expenses due to the
          special meeting held by the company during the period.

PLAN OF OPERATIONS AND CASH REQUIREMENTS OVER THE NEXT 12 MONTHS

Without adequate funding, it is management's intention to halt current research
and development efforts associated with our biomarker program and wait until
sufficient financial resources exist before spending additional and significant
funds for the commercialization of our biomarker program. However, we will
continue to evaluate and determine the most cost effective use of available
funds for all future research and development programs, including diagnostic
biomarkers, biomarkers for a drug response assay and drug development efforts.

There is no assurance that our research and development programs will produce
commercially viable products or treatments, and a great deal of additional
research and development will be required before a final evaluation of the
economic feasibility of our technologies can be determined.

We are also currently seeking new acquisitions and/or business opportunities
with established business entities for the merger of a target business with our
company including businesses not having a resource focus. In certain instances,
a target business may wish to become a subsidiary of us or may wish to
contribute assets to us rather than merge. There can be no assurance that we
will be able to enter into any agreements. We anticipate that any new
acquisition or business opportunities by our company will require additional
financing. There can be no assurance, however, that we will be able to acquire
the financing necessary to enable us to pursue our plan of operation. If our
company requires additional financing and we are unable to acquire such funds,
our business may fail.

ANTICIPATED CASH REQUIREMENTS

Over the next 12 months, we have estimated our minimum cash requirements to be
as follows:

            ESTIMATED CASH EXPENSES FOR THE NEXT TWELVE MONTH PERIOD

Cash Operating Expenses
  Professional fees                                                      $20,000
  General and administrative expenses                                    $20,000
  Corporate communications                                               $ 5,000
                                                                         -------
Total                                                                    $45,000
                                                                         =======

For the three and months ended December 31, 2012, we recorded a net operating
loss, before other items, of $29,217 and have accumulated losses of $7,109,971
since inception. As at December 31, 2012, we had a working capital deficiency of

                                       18

$55,981 and for the next twelve months, management estimates minimum cash
requirements of $45,000 to fund on-going operations.

Accordingly, we do not have sufficient funds to meet our plan of operation over
the next twelve months and will need to obtain further financing through
issuance of shares, debentures or convertible debentures. We will also endeavor
to access available funding from research and development grants or loans from
various public and private research granting agencies. Moreover, all cash
operating expenses will be carefully monitored to ensure we can meet our
obligations as they come due.

There can be no assurance that additional financing will be available when
needed or, if available, on commercially reasonable terms. If we are not able to
obtain additional financing on a timely basis, we may not be able to meet our
obligations as they come due.

LIQUIDITY AND CAPITAL RESOURCES

Our financial positions as at December 31, 2012 and September 30, 2012 are as
follows:

WORKING CAPITAL

                                                   As at              As at
                                                December 31,       September 30,
                                                   2012               2012
                                                 --------           --------
                                                (unaudited)         (audited)
Current assets                                   $  3,190           $  7,812
Current liabilities                                59,171             34,576
Working capital deficiency                       $(55,981)          $(26,764)

Working capital deficiency has increased from $26,764 at September 30, 2012 to
$55,981 at December 31, 2012. To date, we have had negative cash flows from
operations and we have been dependent on sales of our equity securities and debt
financing to meet our cash requirements. We expect this situation to continue
for the foreseeable future. We anticipate that we will have negative cash flows
during the next twelve month period.

CASH FLOWS

                                                Three Months       Three Months
                                                   Ended              Ended
                                                December 31,       December 31,
                                                   2012               2011
                                                 --------           --------
Net cash used in operating activities            $(24,070)          $ (7,316)
Net cash from investing activities               $     --           $     --
Net cash provided by financing activities        $ 20,823           $     --
Effect of exchange rate changes                  $     --           $    207
Decrease in cash during the period               $ (3,247)          $ (7,109)
Cash, beginning of period                        $  4,312           $ 12,602
Cash, end of period                              $  1,065           $  5,493

During the three month period ended December 30, 2012 and 2011:

     i)   Our net cash used in operating activities increased from $7,316 to
          $24,070 primarily due to our ( company holding a special meeting
          during the period and incurring various costs related to the meeting;

     (ii) Our net cash from investing activities was $nil in 2012 and $nil in
          2011.

     (iii) Our net cash from financing activities was $20,823 in 2012 and $nil
          in 2011.

                                       19

GOING CONCERN

The audited financial statements accompanying our annual report on Form 10-K
have been prepared on a going concern basis, which implies that our company will
continue to realize its assets and discharge its liabilities and commitments in
the normal course of business. Our company has not generated revenues since
inception, has never paid any dividends and is unlikely to pay dividends or
generate earnings in the immediate or foreseeable future. The continuation of
our company as a going concern is dependent upon: (i) the continued financial
support from our shareholders; (ii) the ability of our company to continue
raising necessary equity financing to achieve its operating objectives; and
(iii) the eventual attainment of profitable operations.

Our independent auditors included an explanatory paragraph in their annual
report on our financial statements for the year ended September 30, 2011
regarding concerns about our ability to continue as a going concern. In
addition, our financial statements contain further note disclosures in this
regard. The continuation of our business plan is dependent upon our ability to
continue raising sufficient new capital from equity or debt markets in order to
fund our on-going operating losses. The issuance of additional equity securities
could result in a significant dilution in the equity interests of our current
stockholders.

APPLICATION OF CRITICAL ACCOUNTING POLICIES

The preparation of financial statements in conformity with United States
generally accepted accounting principles requires management to make estimates
and assumptions that affect the amounts reported in the financial statements and
accompanying disclosures of our company. Although these estimates are based on
management's knowledge of current events and actions that our company may
undertake in the future, actual results may differ from such estimates.

BASIS OF PRESENTATION

These financial statements and related notes are presented in accordance with
United States generally accepted accounting principles ("US GAAP") and are
expressed in US dollars. Our company is in the development stage and has not
realized significant revenues from its business plan to date. These financial
statements include the accounts of our company and our previously wholly-owned
Canadian subsidiaries up to the date of their disposal.

USE OF ESTIMATES AND ASSUMPTIONS

The preparation of financial statements in conformity with US GAAP requires our
company to make estimates and assumptions that affect the reported amounts of
assets and liabilities and disclosure of contingent assets and liabilities at
the date of the financial statements and the reported amounts of revenue and
expenses during the reporting period. We base our estimates and assumptions on
current facts, historical experience and various other factors that we believe
to be reasonable under the circumstances, the results of which form the basis
for making judgments about the carrying values of assets and liabilities and the
accrual of costs and expenses that are readily apparent from other sources. The
actual results experienced by our company may differ materially from our
company's estimates. To the extent there are material differences, future
results may be affected. There were no significant estimates used in preparing
these financial statements.

SHARE-BASED COMPENSATION

Our company accounts for share-based compensation using the fair value method
and related compensation expense is recognized over the period of benefit when
the service is rendered.

FINANCIAL INSTRUMENTS

Our company's financial instruments consist of cash, accounts payable and due to
related parties. The carrying amounts of these financial instruments approximate
their fair values due to their short term nature.

                                       20

FOREIGN CURRENCY TRANSACTIONS AND TRANSLATION

The functional of our company is the Canadian dollar and the reporting currency
is the United States dollar. The financial statements are translated into United
States dollars using period-end rates of exchange for assets and liabilities,
and period average rates of exchange for revenues and expenses. Foreign currency
transaction gains (losses) are included in the statements of operations and
those arising from translation are included in other comprehensive income (loss)
which is disclosed as a separate component of shareholders' deficit. Our company
has not entered into any derivative instruments to offset the impact of foreign
currency fluctuations.

RESEARCH AND DEVELOPMENT

These costs were expensed when incurred and consisted primarily of direct
material and personnel costs, contract services and indirect costs. Our company
has received government assistance in the past and may receive same in the
future regarding research and development activities. When work is performed
that qualifies for such grants, the related assistance amount is credited to
research and development expense. There were no research or development
expenditures incurred during the period.

INCOME TAXES

Our company uses the asset and liability method of accounting for income taxes.
Under this method, deferred tax assets and liabilities are determined based on
temporary differences between the financial statements and the tax basis of
assets and liabilities, and net operating loss carry forwards based on using
enacted tax rates in effect for the year in which the differences are expected
to reverse. The effect of a change in tax rates on deferred tax assets and
liabilities is recognized in income in the year that includes the enactment
date. Valuation allowances are established to the extent that it is considered
more likely than not that deferred tax assets will be realized. A valuation
allowance for the full amount of the deferred tax assets has been recorded.

LOSS PER SHARE

Basic loss per share is computed by dividing the net loss by the weighted
average number of outstanding common shares during the year. Diluted loss per
share gives effect to all potentially dilutive common shares outstanding during
the year, including convertible debt, stock options and share purchase warrants,
using the treasury stock method. The computation of diluted loss per share does
not assume conversion, exercise or contingent exercise of securities that would
have an anti-dilutive effect on loss per share.

RECENT ACCOUNTING PRONOUNCEMENTS

Our company has reviewed recently issued, but not yet effective, accounting
pronouncements and plans to adopt those that are applicable to it. Due to our
limited activity we do not expect the adoption of these pronouncements to have a
material impact on our reported financial position, results of operations or
cash flows.

OFF-BALANCE SHEET ARRANGEMENTS

We have no significant off-balance sheet arrangements that have or are
reasonably likely to have a current or future effect on our financial condition,
changes in financial position, revenues and expenses, results of operations,
liquidity, capital expenditures or capital resources that are material to
stockholders.

ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK.

Not Applicable.

                                       21

ITEM 4. CONTROLS AND PROCEDURES.

DISCLOSURE CONTROLS AND PROCEDURES

As required by paragraph (b) of Rules 13a-15 or 15d-15 under the Exchange Act,
our principal executive officer and principal financial officer evaluated our
company's disclosure controls and procedures (as defined in Rules 13a-15(e) and
15d-15(e) of the Exchange Act) as of the end of the period covered by this
quarterly report on Form 10-Q. Based on this evaluation, these officers
concluded that as of the end of the period covered by this quarterly report on
Form 10-Q, these disclosure controls and procedures were not effective to ensure
that the information required to be disclosed by our company in reports it files
or submits under the Exchange Act is recorded, processed, summarized and
reported within the time periods specified in the rules and forms of the
Securities Exchange Commission and include controls and procedures designed to
ensure that such information is accumulated and communicated to our company's
management, including our company's principal executive officer and principal
financial officer, to allow timely decisions regarding required disclosure. The
conclusion that our disclosure controls and procedures were not effective was
due to the presence of the following material weaknesses in internal control
over financial reporting which are indicative of many small companies with small
staff: (i) inadequate segregation of duties and effective risk assessment; (ii)
insufficient written policies and procedures for accounting and financial
reporting with respect to the requirements and application of both US GAAP and
SEC guidelines; (iii) inadequate security and restricted access to computer
systems including insufficient disaster recovery plans; and (iv) no written
whistle-blower policy.

Our company plans to take steps to enhance and improve the design of our
internal controls over financial reporting. During the period covered by this
quarterly report on Form 10-Q, we have not been able to remediate the material
weaknesses identified above. To remediate such weaknesses, we plan to implement
the following changes during our fiscal year ending September 30, 2012: (i)
appoint additional qualified personnel to address inadequate segregation of
duties and ineffective risk management; (ii) adopt sufficient written policies
and procedures for accounting and financial reporting and a whistle-blower
policy; and (iii) implement sufficient security and restricted access measures
regarding our computer systems and implement a disaster recovery plan. The
remediation efforts set out in (i) and (iii) are largely dependent upon our
company securing additional financing to cover the costs of implementing the
changes required. If we are unsuccessful in securing such funds, remediation
efforts may be adversely effected in a material manner.

Because of the inherent limitations in all control systems, no evaluation of
controls can provide absolute assurance that all control issues, if any, within
our company have been detected. These inherent limitations include the realities
that judgments in decision-making can be faulty and that breakdowns can occur
because of simple error or mistake.

CHANGES IN INTERNAL CONTROL OVER FINANCIAL REPORTING.

There were no changes in our company's internal control over financial reporting
during the period ended December 31, 2012, that affected our company's internal
control over financial reporting subsequent to the date that we carried out our
evaluation for that period.

                           PART II - OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS.

We know of no material, active, or pending legal proceeding against our company,
nor are we involved as a plaintiff in any material proceeding or pending
litigation where such claim or action involves damages for more than 10% of our
current assets. Additionally, there were no proceedings in which any of our
company's directors, officers, or affiliates, or any registered or beneficial
shareholders holding more than 5% of our voting securities, is an adverse party
or has a material interest adverse to our company's interest.

                                       22

ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS.

None.

ITEM 3. DEFAULTS UPON SENIOR SECURITIES.

None.

ITEM 4. MINE SAFETY DISCLOSURES

None.

ITEM 5. OTHER INFORMATION.

None.

ITEM 6. EXHIBITS.

Exhibit
Number                              Description
------                              -----------

(2)       PLAN OF PURCHASE, SALE, REORGANIZATION, ARRANGEMENT, LIQUIDATION OR
          SUCCESSION

2.1       Share Exchange Agreement dated February 3, 2006, among our company,
          Upstream Canada, the shareholders of Upstream Canada and Steve Bajic
          (incorporated by reference from our Current Report on Form 8-K filed
          on February 6, 2006).

2.2       Amended and Restated Share Exchange Agreement dated February 24, 2006,
          among our company, Upstream Canada, the shareholders of Upstream
          Canada and Steve Bajic (incorporated by reference from our Current
          Report on Form 8-K filed on February 27, 2006).

(3)       ARTICLES OF INCORPORATION AND BY-LAWS

3.1       Articles of Incorporation (incorporated by reference from our
          Registration Statement on Form SB-2 filed on July 5, 2002).

3.2       Bylaws (incorporated by reference from our Registration Statement on
          Form SB-2 Filed on July 5, 2002).

3.3       Certificate of Amendment filed with the Nevada Secretary of State on
          March 8, 2005 (incorporated by reference from our Current Report on
          Form 8-K filed on March 10, 2005).

3.4       Certificate of Change filed with the Nevada Secretary of State on
          December 20, 2005 (incorporated by reference from our Current Report
          on Form 8-K filed on December 29, 2005).

3.5       Articles of Merger filed with the Nevada Secretary of State on
          February 6, 2006 (incorporated by reference from our Current Report on
          Form 8-K filed on February 9, 2006).

3.6       Certificate of Amendment filed with the Nevada Secretary of State on
          November 27, 2006 (incorporated by reference from our Current Report
          on Form 8-K filed on November 30, 2006).

(10)      MATERIAL CONTRACTS

10.1      2007 Stock Option Plan (incorporated by reference from our
          Registration Statement on Form SB-2 filed on October 1, 2007).

                                       23

10.2      Amendment to Employment Agreement dated August 18, 2009 between our
          company and Dexster Smith (incorporated by reference from our
          Quarterly Report on Form 10-Q filed on August 31, 2009).

10.3      Amendment to Employment Agreement dated August 18, 2009 between our
          company and Joel Bellenson (incorporated by reference from our
          Quarterly Report on Form 10-Q filed on August 31, 2009).

10.4      Return to Treasury Agreement dated December 14, 2009 between our
          company and Joel Bellenson (incorporated by reference from our Current
          Report on Form 8-K filed on December 14, 2009).

10.5      Return to Treasury Agreement dated December 14, 2009 between our
          company and Dexster Smith (incorporated by reference from our Current
          Report on Form 8-K filed on December 14, 2009).

10.6      Asset Sale Agreement dated December 14, 2009 between Pacific Pharma
          Technologies Inc. and JTAT Consulting Inc. (incorporated by reference
          from our Current Report on Form 8-K filed on December 14, 2009).

(31)      SECTION 302 CERTIFICATIONS

31.1*     Certification of Principal Executive Officer and Principal Financial
          Officer filed pursuant to Section 302 of the Sarbanes-Oxley Act of
          2002.

(32)      SECTION 906 CERTIFICATIONS

32.1*     Certification of Principal Executive Officer and Principal Financial
          Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to
          Section 906 of the Sarbanes-Oxley Act of 2002.

(99)      ADDITIONAL EXHIBITS

99.1      Compensation Committee Charter (incorporated by reference from our
          Annual Report on Form 10-K filed on December 19, 2008)

99.2      Audit Commission Charter (incorporated by reference from our Annual
          Report on Form 10-K filed on December 19, 2008)

101*      Interactive data files pursuant to Rule 405 of Regulation S-T

----------
* Filed herewith

                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.

UPSTREAM BIOSCIENCES INC.


By: /s/ Charles El-Moussa
   -------------------------------------------------
   Charles El Moussa
   Chief Financial Officer, President,
   Chief Executive Officer, Treasurer and Director
   (Principal Executive Officer, Principal Financial
   Officer and Principal Accounting Officer)

Dated: February 14, 2013

                                       24