Exhibit 32.1

         CERTIFICATION OF CHIEF EXECUTIVE OFFICER PURSUANT TO TITLE 18,
            UNITED STATES CODE, SECTION 1350, AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

I, Anthony A. Lombardo, President, Chief Executive Officer and Director of E-Z-
EM, Inc. (the "Company"), certify, pursuant to Section 906 of the Sarbanes-Oxley
Act of 2002, 18 U.S.C. Section 1350, that, to the best of my knowledge:

      1.    the Quarterly Report on Form 10-Q of the Company for the quarter
            ended February 28, 2004 (the "Report") fully complies with the
            requirements of Section 13(a) or 15(d) of the Securities Exchange
            Act of 1934 (15 U.S.C. 78m or 78o(d); and

      2.    the information contained in the Report fairly presents, in all
            material respects, the financial condition and results of operations
            of the Company.

Date April 8, 2004               /s/ Anthony A. Lombardo
     --------------              -------------------------------------
                                 Anthony A. Lombardo, President,
                                 Chief Executive Officer and Director


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