- --------------------------------------------------------------------------------
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                             -----------------------

                                    FORM 10-Q


                QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(D)
                     OF THE SECURITIES EXCHANGE ACT OF 1934
                             -----------------------

                FOR THE QUARTERLY PERIOD ENDED SEPTEMBER 30, 2002

                        COMMISSION FILE NUMBER 000-21930


                          BIOSOURCE INTERNATIONAL, INC.
             (Exact name of Registrant as specified in its charter)

          DELAWARE                                               77-0340829
(State or other jurisdiction of                              (I.R.S. Employer
 incorporation or organization)                              Identification No.)


542 FLYNN ROAD, CAMARILLO, CALIFORNIA                              93012
(Address of principal executive offices)                        (Zip Code)


       Registrant's telephone number, including area code: (805) 987-0086


     Indicate  by check mark  whether the  Registrant  (1) has filed all reports
required to be filed by Section 13 or 15(d) of the  Securities  Exchange  Act of
1934  during the  preceding  12 months  (or for such  shorter  periods  that the
Registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the past 90 days.


                          YES /X/              NO / /


     The number of shares of the  Registrant's  common  stock,  $.001 par value,
outstanding as of November 8, 2002 was 9,644,916.


- --------------------------------------------------------------------------------





                 BIOSOURCE INTERNATIONAL, INC. AND SUBSIDIARIES
                                    FORM 10-Q
                               SEPTEMBER 30, 2002

                                      INDEX


                                                                        PAGE NO.
                                                                        --------
                          PART I. FINANCIAL INFORMATION

ITEM 1.  FINANCIAL STATEMENTS

                  Condensed Consolidated Balance Sheets
                  as of September 30, 2002 (unaudited)
                  and December 31, 2001 (unaudited) ........................ 3

                  Condensed Consolidated Statements of
                  Operations for the three and nine months
                  ended September 30, 2002 and 2001 (unaudited) ............ 4

                  Condensed Consolidated Statements of
                  Cash Flows for the nine months ended
                  September 30, 2002 and 2001 (unaudited) .................. 5

                  Notes to Condensed Consolidated Unaudited
                  Financial Statements ..................................... 6

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
         CONDITION AND RESULTS OF OPERATIONS ...............................10

ITEM 3.  QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT
         MARKET RISK .......................................................24

ITEM 4.  CONTROLS AND PROCEDURES ...........................................24


                           PART II. OTHER INFORMATION

ITEM 1.  LEGAL PROCEEDINGS .................................................26

ITEM 2.  CHANGES IN SECURITIES AND USE OF PROCEEDS .........................26

ITEM 3.  DEFAULTS UPON SENIOR SECURITIES ...................................26

ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS ...............26

ITEM 5.  OTHER INFORMATION .................................................26

ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K ..................................27

SIGNATURES .................................................................28


                                       2





                 BIOSOURCE INTERNATIONAL, INC. AND SUBSIDIARIES
                      CONDENSED CONSOLIDATED BALANCE SHEETS
                             (Amounts in thousands)
                                   (Unaudited)


                                                     SEPTEMBER 30,  DECEMBER 31,
                                                           2002          2001
                                                         --------      --------
ASSETS
Current assets:
   Cash and cash equivalents .......................     $  5,798         9,471
   Accounts receivable, less allowance
     for doubtful accounts of $347 at
     September 30, 2002 and $261 at
     December 31, 2001 .............................        6,520         6,184
   Inventories, net (note 3) .......................        8,133         7,184
   Prepaid expenses and other current
     assets ........................................          739           540
   Deferred income taxes ...........................        1,584         1,584
                                                         --------      --------
                  Total current assets .............       22,774        24,963

Property and equipment, net (note 4) ...............        6,949         5,408
Intangible assets net of accumulated
  amortization of $2,318 at September
  30, 2002 and $2,101 at December 31,
  2001 (note 5) ....................................        6,259         6,912
Goodwill, net of accumulated
  amortization of $176 at September 30,
  2002 and $1,276 at December 31, 2001
  (note 5) .........................................          284         4,741
Other assets .......................................          520           491
Deferred tax assets ................................        8,826         7,326
                                                         --------      --------
                                                         $ 45,612        49,841
                                                         ========      ========
LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
   Accounts payable ................................     $  2,533         2,416
   Accrued expenses ................................        2,702         2,707
   Deferred revenue ................................          439           404
   Income tax payable ..............................          815           436
                                                         --------      --------
                  Total current liabilities ........        6,489         5,963
                                                         --------      --------
Commitments and contingencies

Stockholders' equity:
  Common stock, $.001 par value. Authorized
         20,000,000 shares: issued
         9,696,582 and outstanding
         9,644,582 shares at September 30,
         2002; issued 10,449,817 shares
         and outstanding 10,353,817
         shares at December 31, 2001 ...............           10            10
  Additional paid-in capital .......................       44,373        48,761
  Accumulated deficit ..............................       (3,427)       (2,330)
  Accumulated other comprehensive loss .............       (1,833)       (2,563)
                                                         --------      --------
                  Net stockholders' equity .........       39,123        43,878
                                                         --------      --------
                                                         $ 45,612        49,841
                                                         ========      ========

The  accompanying  notes are an integral  part of these  condensed  consolidated
financial statements.


                                       3





                 BIOSOURCE INTERNATIONAL, INC. AND SUBSIDIARIES
                 CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
             THREE AND NINE MONTHS ENDED SEPTEMBER 30, 2002 AND 2001
                  (Amounts in thousands, except per share data)
                                   (Unaudited)

                                    THREE MONTHS ENDED        NINE MONTHS ENDED
                                       SEPTEMBER 30,            SEPTEMBER 30,
                                   --------------------    --------------------
                                     2002        2001        2002        2001
                                   --------    --------    --------    --------

Net sales ......................   $ 10,101       8,587      30,175      26,004
Cost of sales ..................      4,365       3,761      13,109      11,397
                                   --------    --------    --------    --------
    Gross profit ...............      5,736       4,826      17,066      14,607
                                   --------    --------    --------    --------

Operating expenses:
    Research and development ...      1,557       1,051       4,362       2,930
    Sales and marketing ........      1,961       1,806       6,239       5,552
    General and administrative .      1,394       1,751       4,325       4,918
    Amortization of intangibles
      assets and goodwill ......        160         275         481         824
                                   --------    --------    --------    --------
        Total operating expenses      5,072       4,883      15,407      14,224
                                   --------    --------    --------    --------
Operating income ...............        664         (57)      1,659         383

Interest income ................         21          85          82         330
Other income (expense), net ....         (8)        (28)        (10)         47
                                   --------    --------    --------    --------
Income before income taxes
  (benefit) ....................        677           0       1,731         760
Income tax expense (benefit) ...        149        (266)        381         (30)
                                   --------    --------    --------    --------
        Income before cumulative
          effect of accounting
          change ...............        528         266       1,350         790
Cumulative effect of accounting
  change (net of applicable
  income taxes (benefit) of
  ($259) and $1,500 for the
  three and nine months ended
  September 30, 2002,
  respectively) ................        423        --        (2,447)       --
                                   --------    --------    --------    --------

Net income (loss) ..............   $    951         266      (1,097)        790
                                   ========    ========    ========    ========

Net income per share before
  accounting change:
    Basic ......................   $   0.05        0.03        0.14        0.08
                                   ========    ========    ========    ========
    Diluted ....................   $   0.05        0.02        0.13        0.07
                                   ========    ========    ========    ========

Net income (loss) per share
  after accounting change:
    Basic ......................   $   0.10        0.03       (0.11)       0.08
                                   ========    ========    ========    ========
    Diluted ....................   $   0.09        0.02       (0.11)       0.07
                                   ========    ========    ========    ========

Shares used to compute net
  income (loss):
    Basic ......................      9,651      10,443       9,830      10,400
                                   ========    ========    ========    ========
    Diluted ....................     10,029      10,868      10,289      11,003
                                   ========    ========    ========    ========


The  accompanying  notes are an integral  part of these  condensed  consolidated
financial statements.


                                       4





                 BIOSOURCE INTERNATIONAL, INC. AND SUBSIDIARIES
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                  NINE MONTHS ENDED SEPTEMBER 30, 2002 AND 2001
                             (Amounts in thousands)
                                   (Unaudited)


                                                            2002          2001
                                                          -------       -------

Cash flows from operating activities:
     Net income (loss) .............................      $(1,097)          790
     Adjustments to reconcile net income
       (loss) to net cash provided by
       operating activities:
          Depreciation and amortization ............        1,686         1,662
          Stock compensation .......................         --            (388)
          Cumulative effect of accounting
            change - goodwill write-off ............        4,629          --
          Income tax benefit from the
            exercise of stock options ..............         --              94
     Changes in assets and liabilities:
          Accounts receivable ......................          (33)         (476)
          Inventories ..............................         (516)         (102)
          Prepaid expenses and other
            current assets .........................         (192)           19
          Deferred taxes ...........................       (1,500)          (94)
          Other assets .............................          (31)          305
          Accounts payable .........................           13           355
          Accrued expenses .........................         (173)         (151)
          Deferred revenue .........................           35           (61)
          Income taxes payable .....................          375             7
                                                          -------       -------
     Net cash provided from operating
       activities ..................................        3,196         1,960
                                                          -------       -------

Cash flows from investing activities:
     Purchase of property and equipment ............       (2,632)       (1,625)
                                                          -------       -------
          Net cash used in investing
            activities .............................       (2,632)       (1,625)
                                                          -------       -------

Cash flows from financing activities:
     Proceeds from the exercise of options .........          224           295
     Purchase of treasury stock ....................       (4,611)         --
                                                          -------       -------
Net cash provided by (used in) financing
  activities .......................................       (4,387)          295
                                                          -------       -------

          Net decrease in cash and cash
            equivalents ............................       (3,823)          630
Effect of exchange rates on cash and cash
  equivalents ......................................          150          (417)

Cash and cash equivalents at beginning of
  period ...........................................        9,471        10,633
                                                          -------       -------

Cash and cash equivalents at end of period .........      $ 5,798        10,846
                                                          =======       =======

Supplemental disclosure of cash flow
  information:
     Cash paid during the period
      for:
          Interest .................................      $     1             1
                                                          =======       =======
          Income taxes .............................      $    24          --
                                                          =======       =======

The  accompanying  notes are an integral  part of these  condensed  consolidated
financial statements.


                                       5





BIOSOURCE INTERNATIONAL, INC. AND SUBSIDIARIES
NOTES TO CONDENSED CONSOLIDATED UNAUDITED FINANCIAL STATEMENTS

1.   BASIS OF PRESENTATION

The  accompanying  condensed  consolidated  financial  statements  of  BioSource
International,  Inc.  (the  "Company")  are  unaudited  and have  been  prepared
pursuant to the rules and regulations of the Securities and Exchange  Commission
regarding interim financial reporting.  Accordingly,  they do not include all of
the  information  and  footnotes  required  by  generally  accepted   accounting
principles for complete  financial  statements and should be read in conjunction
with the  consolidated  financial  statements and notes thereto  included in our
Annual Report on Form 10-K,  for the fiscal year ended December 31, 2001. In the
opinion  of  management,   the  accompanying  unaudited  condensed  consolidated
financial  statements  include all  adjustments  that are  necessary  for a fair
presentation.  The results of  operations  for the three and nine  months  ended
September 30, 2002, are not necessarily indicative of results to be expected for
the full fiscal year.

2.   GENERAL

The  Company  develops,  manufactures,  markets  and  distributes  products  and
services that are widely used in biomedical research.  Our products and services
enable  scientists to better  understand the  biochemistry,  immunology and cell
biology of the human body, aging and certain diseases such as cancer,  arthritis
and other inflammatory diseases,  AIDS and certain other infectious diseases. We
have a wide  variety of  products,  including  immunoassay  and ELISA test kits;
immunological reagents, including bioactive proteins (cytokines,  growth factors
and  adhesion  molecules),   oligonucleotides,  and  monoclonal  and  polyclonal
antibodies. We also manufacture and market custom oligonucleotides, peptides and
antibodies  to the  specifications  of our  customers.  We use  recombinant  DNA
technology to produce cytokines and other proteins.

RECENTLY ISSUED ACCOUNTING STANDARDS

In July 2001, the Financial Accounting Standards Board ("FASB") issued Statement
of Financial  Accounting  Standards  ("FAS")  No.141,  "Accounting  For Business
Combinations,"  and FAS No. 142,  "Accounting For Goodwill and Other  Intangible
Assets." FAS No. 141 requires that the purchase method of accounting be used for
all business  combinations  initiated  after June 30, 2001. FAS No. 142 requires
that goodwill and intangible  assets with  indefinite  useful lives no longer be
amortized to earnings, but instead be reviewed for impairment in accordance with
FAS No. 142. The amortization of goodwill and intangible  assets with indefinite
lives was  approximately  $160,000 and $275,000 for the quarters ended September
30, 2002 and 2001,  respectively  and  $481,000 and $824,000 for the nine months
ended September 30, 2002 and 2001  respectively.  Effective January 1, 2002, the
Company's  goodwill and other intangible  assets are accounted for under FAS No.
141  "Business  Combinations"  and FAS No. 142  "Goodwill  and Other  Intangible
Assets." In the first quarter of 2002, the Company recognized a non-cash charge,
net of applicable income taxes, of $2,870,000 representing the cumulative effect
of a change in accounting  principle  resulting from the  implementation  of FAS
142. The charge included the write off of goodwill related to the acquisition of
Quality Controlled  Biochemicals  ("QCB") in December 1998. In the third quarter
of 2002,  the Company  received  cash  proceeds  of  $800,000 in an  arbitration
settlement  related to its 1998 acquisition of QCB. This recovery,  shown net of
legal  fees and  applicable  income  taxes,  totals  $423,000  and is shown as a
cumulative effect of a change in accounting principle for the three months ended
September 30, 2002.  The net impairment  charge for goodwill  resulting from the
adoption of FAS 142 for the nine months ended  September  30, 2002 is $2,447,000
and is shown in the accompanying  condensed consolidated statement of operations
as a cumulative effect of an accounting change.

In October 2001, the FASB issued FAS No. 144,  "Accounting for the Impairment or
Disposal  of  Long-Lived  Assets,"  which  addresses  financial  accounting  and
reporting for the impairment or disposal of long-lived assets. While FAS No. 144
supersedes FAS No.121,  "Accounting for the Impairment of Long-Lived  Assets and
for  Long-Lived  Assets to be Disposed  Of," it retains many of the  fundamental
provisions  of that  statement.  The  standard  is  effective  for fiscal  years
beginning after December 15, 2001. The implementation of FAS No. 144 has not had
a material impact on our financial position or results from operations.


                                       6





On July 30, 2002, the FASB issued FAS No. 146,  "Accounting for Costs Associated
with Exit or  Disposal  Activities."  FAS 146  nullifies  EITF  Issue No.  94-3,
"Liability Recognition for Certain Employee Termination Benefits and Other Costs
to Exit an Activity  (including Certain Costs Incurred in a Restructuring)."  It
requires that a liability be recognized  for those costs only when the liability
is incurred,  that is, when it meets the definition of a liability in the FASB's
conceptual  framework.  FAS No. 146 also establishes fair value as the objective
for initial measurement of liabilities  related to exit or disposal  activities.
FAS 146 is effective for exit or disposal  activities  that are initiated  after
December 31, 2002, with earlier adoption encouraged. The Company does not expect
that the  adoption  of FAS 146 will  have a  material  impact  on its  financial
position or results from operations.

3.   INVENTORIES (AMOUNTS IN THOUSANDS):

                                         SEPT. 30, 2002         DEC. 31, 2001
                                         --------------         -------------

     Raw materials ......................  $    2,484                 2,367
     Work in process ....................         534                   304
     Finished goods .....................       5,115                 4,513
                                           ----------            ----------
                                           $    8,133                 7,184
                                           ==========            ==========

4.   PROPERTY AND EQUIPMENT (AMOUNTS IN THOUSANDS):

                                         SEPT. 30, 2002         DEC. 31, 2001
                                         --------------         -------------

     Machinery and equipment ............  $    8,485                 6,919
     Office furniture and equipment .....       3,466                 2,604
     Leasehold improvements .............       1,468                   907
                                           ----------            ----------
                                               13,419                10,430
     Less accumulated depreciation
        and amortization ................       6,470                 5,022
                                           ----------            ----------
                                           $    6,949                 5,408
                                           ==========            ==========

5.   GOODWILL AND INTANGIBLE ASSETS - ADOPTION OF FINANCIAL ACCOUNTING STATEMENT
     142

In  July  2001,   the  FASB  issued  FAS  No.141,   "Accounting   For   Business
Combinations,"  and FAS No. 142,  "Accounting For Goodwill and Other  Intangible
Assets."

The pro forma effects of  implementation of FAS 142 to prior periods would be as
follows (amounts in thousands, except per share data):

                                                 NINE MONTHS ENDED SEPTEMBER 30,
                                                       2002          2001
                                                    ---------      --------

     REPORTED INCOME (LOSS) ...................     $  (1,097)          790
     Add:
     Impairment charge ........................         2,447          --
     Goodwill Amortization, net of tax ........          --             213
                                                    ---------      --------
     Adjusted net income ......................     $   1,350         1,003
                                                    =========      ========

     BASIC NET INCOME PER SHARE:
         Reported income (loss) ...............     $   (0.11)         0.08
         Impairment charge ....................          0.25          0.00
         Goodwill amortization ................          0.00          0.02
                                                    ---------      --------
         Adjusted net income ..................     $    0.14          0.10
                                                    =========      ========

     DILUTED NET INCOME PER SHARE:
         Reported income (loss) ...............     $   (0.11)         0.07
         Impairment charge ....................          0.24          0.00
         Goodwill amortization ................          0.00          0.02
                                                    ---------      --------
         Adjusted net income ..................     $    0.13          0.09
                                                    =========      ========


                                       7





6.   EARNINGS PER SHARE

The  reconciliation  of basic to diluted  weighted  average shares is as follows
(amounts in thousands):

                                                THREE MONTHS       NINE MONTHS
                                                    ENDED             ENDED
                                                SEPTEMBER 30,     SEPTEMBER 30,
                                                2002     2001     2002     2001
                                               ------   ------   ------   ------

Weighted average shares used in
     basic computation .....................    9,651   10,443    9,830   10,400

Dilutive stock options and warrants ........      378      425      459      603
                                               ------   ------   ------   ------

Weighted average shares used for
     diluted computation ...................   10,029   10,868   10,289   11,003
                                               ======   ======   ======   ======


Options to purchase  1,212,904  and  1,039,613  shares were not  included in the
computation  of diluted net income per share for the three month  periods  ended
September  30,  2002  and  2001,  respectively  because  their  effect  would be
anti-dilutive.

Options to  purchase  1,122,276  and  822,443  shares  were not  included in the
computation  of diluted net income  (loss) per share for the nine month  periods
ended  September 30, 2002 and 2001,  respectively  because their effect would be
anti-dilutive.

Warrants to purchase  1,287,000  shares at a weighted  average exercise price of
$7.77 per share were  outstanding as of September 30, 2002 and 2001 but were not
included  in the  computation  of diluted net income per share for the three and
nine months  ended  September  30, 2002 and 2001  because  their effect would be
anti-dilutive.


7.   STOCKHOLDERS' EQUITY

Comprehensive income (loss) is determined as follows (amounts in thousands):

                                                THREE MONTHS      NINE MONTHS
                                                    ENDED            ENDED
                                                SEPTEMBER 30,    SEPTEMBER 30,
                                              2002     2001     2002      2001
                                             ------   ------   ------    ------

Net income (loss) ........................   $  951      266   (1,097)      790

Foreign currency translation adjustments .       30      409      730      (115)
                                             ------   ------   ------    ------

Total comprehensive income (loss) ........   $  981      675     (367)      675
                                             ======   ======   ======    ======


                                       8





8.   BUSINESS SEGMENTS

The  Company  is  engaged  in a single  industry,  the  licensing,  development,
manufacture, marketing and distribution of immunological reagents, test kits and
oligonucleotides  used  in  biomedical  research  and  human  diagnostics.   Our
customers are not concentrated in any specific  geographic  region and no single
customer accounts for a significant amount of our sales.

Management of the Company has determined  its reportable  segments are strategic
business  units  that offer both sales to  external  customers  from  geographic
company  facilities  and  sales to  external  customers  in  certain  geographic
regions.  Significant  reportable  business  segments are the United  States and
European  facilities,  and sales to external  customers are  summarized as those
located in the United States,  Europe,  Japan and other. We evaluate performance
for  the  "Sales-from"  segments  on  net  revenue  and  profit  and  loss  from
operations.  Our  reportable  segments are strategic  business  units that offer
geographical  product  availability.  They are managed  separately  because each
business  requires  different  marketing and distribution  strategies.  Business
information is summarized as follows:




                                         THREE MONTHS ENDED      NINE MONTHS ENDED
                                            SEPTEMBER 30,          SEPTEMBER 30,
                                        --------------------    --------------------
                                          2002        2001        2002        2001
                                        --------    --------    --------    --------
                                                                
SALES - FROM SEGMENTS (IN THOUSANDS):
Net sales to external customers from:
     United States:
         Domestic ...................   $  5,951    $  5,241    $ 17,952    $ 15,348
         Export .....................      1,055       1,040       3,164       3,403
                                        --------    --------    --------    --------
                Total United States .      7,006       6,281      21,116      18,751
     Europe .........................      3,095       2,306       9,059       7,253
                                        --------    --------    --------    --------
                Consolidated ........   $ 10,101    $  8,587    $ 30,175    $ 26,004
                                        ========    ========    ========    ========

Operating income (loss):
     United States ..................   $    (20)   $   (483)   $   (340)   $ (1,359)
     Europe .........................        684         426       1,999       1,742
                                        --------    --------    --------    --------
                Consolidated ........   $    664    $    (57)   $  1,659    $    383
                                        ========    ========    ========    ========

SALES - TO SEGMENTS (IN THOUSANDS):
Net sales to external customers in:
     United States ..................   $  5,951    $  5,241    $ 17,952    $ 15,348
     Europe .........................      2,725       2,093       7,984       6,706
     Japan ..........................        842         721       2,601       2,276
     Other ..........................        583         532       1,638       1,674
                                        --------    --------    --------    --------
                Consolidated ........   $ 10,101    $  8,587    $ 30,175    $ 26,004
                                        ========    ========    ========    ========




                                       9





ITEM 2. MANAGEMENT'S  DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
OF OPERATIONS


This  discussion  and analysis of financial  condition and results of operations
should be read in conjunction with the consolidated  financial  statements,  the
notes thereto and other information, including information set forth in our 10-K
for the fiscal year ended  December  31, 2001,  and all other recent  filings we
have made with the Securities and Exchange Commission.

This Form 10-Q contains forward-looking  statements,  which are made pursuant to
the safe-harbor  provisions of the Private  Securities  Litigation Reform Act of
1995.   Within   this  Form  10-Q,   words  such  as   "believes,"   "designed,"
"anticipates," and similar expressions are intended to identify  forward-looking
statements,  but are not the exclusive  means of  identifying  such  statements.
These  forward-looking  statements  involve a number of risks and uncertainties,
including  the timely  development  and market  acceptance  of our  products and
technologies  and other factors  described  throughout this Form 10-Q and in our
other filings with the  Securities and Exchange  Commission.  The actual results
that we achieve may differ from any forward-looking statements due to such risks
and  uncertainties.  We do not undertake any  obligation to revise or update any
forward-looking  statements in order to reflect events or circumstances that may
arise after the date of this report.

OVERVIEW

Our  Company  develops,  manufactures,  markets  and  distributes  products  and
services that are widely used in biomedical research.  Our products and services
enable  scientists to better  understand the  biochemistry,  immunology and cell
biology of the human body, aging and certain diseases such as cancer,  arthritis
and other inflammatory diseases,  AIDS and certain other infectious diseases. We
have a wide  variety of  products,  including  immunoassay  and ELISA test kits;
immunological reagents, including bioactive proteins (cytokines,  growth factors
and  adhesion  molecules),   oligonucleotides,  and  monoclonal  and  polyclonal
antibodies. We also manufacture and market custom oligonucleotides, peptides and
antibodies  to the  specifications  of our  customers.  We use  recombinant  DNA
technology  to produce  cytokines and other  proteins.  We have  registered  our
analyte specific reagents with the FDA and have received a license to sell these
products  as Class I Medical  Devices.  We  market  these  products  to IN VITRO
diagnostic   manufacturers  and  clinical  reference   laboratories  as  "active
ingredients" in the tests they produce to identify various specific  diseases or
conditions.  In order to  market  these  products  as  medical  devices,  we are
required to be in compliance with the FDA's Current Good Manufacturing Practices
and Regulations.

CRITICAL ACCOUNTING POLICIES

General

Our discussion and analysis of our financial condition and results of operations
are based upon our consolidated  financial statements,  which have been prepared
in  accordance  with  accounting  principles  generally  accepted  in the United
States.  The  preparation  of these  financial  statements  requires  us to make
estimates and judgments that affect the reported amounts of assets, liabilities,
revenues  and  expenses,   and  related  disclosure  of  contingent  assets  and
liabilities.  On an on-going  basis,  we  evaluate  our  estimates.  We base our
estimates on historical  experience  and on various other  assumptions  that are
believed to be reasonable under the circumstances, the results of which form the
basis for making  judgments  about the carrying values of assets and liabilities
that are not readily apparent from other sources. Actual results may differ from
these  estimates  under  different  assumptions  or  conditions.   Specifically,
management must make estimates in the following areas:


         ALLOWANCE FOR DOUBTFUL  ACCOUNTS.  The Company has  $6,867,000 in gross
         trade  accounts  receivable  and  $347,000 in  allowance  for  doubtful
         accounts at September 30, 2002.  The Company has procedures in place to
         review the credit  worthiness  of new  customers  and also to  properly
         review  orders from  existing  customers  to  determine  if a change in
         credit  terms is  warranted.  A review of our  allowance  for  doubtful
         accounts is done timely and  consistently  throughout  the year.  As of
         September 30, 2002,  we believe our allowance for doubtful  accounts is
         fairly  stated.  We do have  accounts  receivable  amounts from certain
         customers as of September  30, 2002 that if their  financial  condition
         changed and a significant allowance needed to be created, the Company's
         financial results for 2002 could be materially and adversely affected.


                                       10





         INVENTORY  ADJUSTMENTS.  We review the components of our inventory on a
         regular  basis for excess,  obsolete  and impaired  inventory  based on
         estimated  future  usage and sales.  The Company  has written  down its
         entire  antibody  inventory at 100% of its value because the ability to
         sell the antibody inventory is uncertain. As of September 30, 2002, the
         Company had  $3,972,000 of antibodies in its inventory and a write down
         for these antibodies totaling $3,972,000.  The Company will continue to
         monitor  its  antibody  inventory.  Additionally,   material  inventory
         write-downs in our inventory can occur if competitive conditions or new
         product  introductions  by our  customers  or us vary from our  current
         expectations.


         DEFERRED  TAX  ASSETS  AND  DEFERRED  INCOME  TAXES.  The  Company  has
         $10,410,000 in deferred tax assets on its consolidated balance sheet as
         of September 30, 2002. As of September 30, 2002, no valuation allowance
         has been set up to offset any of the deferred  tax assets.  The ability
         to realize these  deferred tax assets  depends  entirely on the Company
         generating   taxable  income  in  the  future.  The  Company  has  used
         historical  information  as well as a  projected  financial  outlook to
         project taxable income amounts.  The Company believes it is more likely
         than  not that  they  will be able to  realize  these  benefits  in the
         future.  A material change in our expected  realization of these assets
         would  occur if the  ability to deduct tax loss  carryforwards  against
         future  taxable  income is altered.  If our  projections  involving tax
         planning and operating  strategies do not materialize or if significant
         changes in tax laws occur within the various tax jurisdictions in which
         we operate,  we would have to set up a valuation  allowance against our
         deferred  tax assets that could  materially  affect our tax expense and
         our financial results.


         REVENUE RECOGNITION. Our revenue is generated from the sale of products
         primarily  manufactured by us. We do have a small amount of products we
         sell on an outside equipment  manufactured  ("OEM") basis. We recognize
         revenue  from all of our  product  sales upon  transfer of title to the
         customer,  which  occurs  upon  shipment.  We  typically  ship  to  our
         customers FOB shipping  point.  We do have  customers who order and pay
         for certain cell  culture  products and request that we store a portion
         of the batch for them.  In these  instances,  we record all payments as
         deferred  revenue in the  consolidated  balance  sheets  and  recognize
         revenue upon  shipment of the product to the customer.  The  Securities
         and Exchange  Commission's Staff Accounting  Bulletin No. 101, "Revenue
         Recognition,"  ("SAB  101")  provides  guidance on the  application  of
         generally   accepted   accounting   principles   to  selected   revenue
         recognition  issues. We believe that our revenue  recognition policy is
         consistent with this guidance and in accordance with generally accepted
         accounting principles.  We do not anticipate any changes to our revenue
         recognition and shipping policies in the future.

         LONG-LIVED ASSETS. In October,  2001 the Financial Accounting Standards
         Board  ("FASB")  issued  Statement  on Financial  Accounting  Standards
         ("FAS")  No.  144,  "Accounting  for  the  Impairment  or  Disposal  of
         Long-Lived Assets," which addresses financial  accounting and reporting
         for the impairment or disposal of long-lived assets.  While FAS No. 144
         supersedes  FAS No.121,  "Accounting  for the  Impairment of Long-Lived
         Assets and for Long-Lived Assets to be Disposed Of," it retains many of
         the fundamental provisions of that statement. The standard is effective
         for fiscal years  beginning  after December 15, 2001. It is our policy,
         and in accordance  with FAS No. 144, to account for long-lived  assets,
         including intangibles,  at amortized cost. As part of an ongoing review
         of the valuation and  amortization  of  long-lived  assets,  management
         assesses the carrying  value of such assets if facts and  circumstances
         suggest  that  they may be  impaired.  If this  review  indicates  that
         long-lived  assets  will  not  be  recoverable,   as  determined  by  a
         non-discounted  cash  flow  analysis  over the  remaining  amortization
         period, the carrying value of the Company's  long-lived assets would be
         reduced to its estimated fair value based on discounted  cash flows. As
         a  result,  we have  determined  that  our  long-lived  assets  are not
         impaired as of September 30, 2002 and 2001, respectively.

         GOODWILL.  In July 2001,  the FASB issued FAS No.141,  "Accounting  For
         Business  Combinations," and FAS No. 142,  "Accounting For Goodwill and
         Other Intangible Assets." FAS No. 141 requires that the purchase method
         of accounting  be used for all business  combinations  initiated  after
         June 30, 2001. FAS No. 142 requires that goodwill and intangible assets
         with  indefinite  useful lives no longer be amortized to earnings,  but
         instead be reviewed for impairment in accordance  with FAS No. 142. The
         amortization of goodwill and intangible  assets with  indefinite  lives
         was approximately $160,000 and $275,000 for the


                                       11





         quarters ended September 30, 2002 and 2001,  respectively  and $481,000
         and  $824,000  for the nine months  ended  September  30, 2002 and 2001
         respectively.  Effective  January 1, 2002,  the Company's  goodwill and
         other  intangible  assets are accounted for under FAS No. 141 "Business
         Combinations"  and FAS No. 142 "Goodwill and Other Intangible  Assets."
         In the first quarter of 2002, the Company recognized a non-cash charge,
         net  of  applicable  income  taxes,  of  $2,870,000   representing  the
         cumulative  effect of a change in accounting  principle  resulting from
         the  implementation  of FAS 142.  The charge  included the write off of
         goodwill related to the acquisition of Quality Controlled  Biochemicals
         ("QCB") in December  1998.  In the third  quarter of 2002,  the Company
         received cash proceeds of $800,000 in an arbitration settlement related
         to its 1998 acquisition of QCB. This recovery,  shown net of legal fees
         and  applicable  income  taxes,  totals  $423,000  and  is  shown  as a
         cumulative  effect of a change in  accounting  principle  for the three
         months ended September 30, 2002. The net impairment charge for goodwill
         resulting  from  the  adoption  of FAS 142 for the  nine  months  ended
         September  30,  2002 is  $2,447,000  and is shown  in the  accompanying
         condensed  consolidated  statement of operations as a cumulative effect
         of an accounting change.

RESULTS OF OPERATIONS FOR THE THREE MONTHS ENDED SEPTEMBER 30, 2002

REVENUES: Net sales for the quarter ended September 30, 2002 were $10.1 million,
an increase of $1.5 million, or 18% (15% after eliminating the $254,000 positive
impact  of  foreign  exchange),  compared  to net sales  for the  quarter  ended
September 30, 2001. The Company's  increased  sales and marketing  expenditures,
including  increased sales personnel and marketing  programs,  and its continued
investment in research and development  activities resulting in new products for
sale,  have been primary  drivers for sales growth in North  America and Europe.
For the three months ended  September 30, 2002,  the Company  achieved net sales
growth in North  America of 12% as compared to the three months ended  September
30, 2001. European sales for the three months ended September 30, 2002 increased
30% (18% in local  currency),  as compared to the comparable  prior year period.
Sales in Japan and the rest of the world  increased  23%,  for the three  months
ended  September  30, 2002 as compared to the three months ended  September  30,
2001.  Solidifying our relationship with our Japanese  distributor through a new
distributor agreement in 2001 and expanding our customer base in the rest of the
world have contributed to our 23% growth in Japan and the rest of the world.

GROSS PROFIT:  Gross profit margin for the three months ended September 30, 2002
was 57%,  compared to 56% for the three months  ended  September  30, 2001.  The
gross  profit  margin was 1% higher for the  quarter  ended  September  30, 2002
primarily due to the selling mix of products.

RESEARCH  AND  DEVELOPMENT:  Research and  development  expenses for the quarter
ended September 30, 2002 and 2001 were $1,557,000 and $1,051,000 and represented
15% and 12% of sales  respectively.  The  increase in research  and  development
expenses  for the three  months ended  September  30, 2002 when  compared to the
comparable  prior year period  reflects the  Company's  investment in additional
personnel and materials in the cytokine and signal  transduction  research areas
with the goal of producing additional novel and proprietary products.

SALES AND  MARKETING:  Selling and marketing  expenses were $2.0 million for the
three  months  ended  September  30, 2002 and $1.8  million for the three months
ended September 30, 2001,  representing 19% and 21% of sales,  respectively.  In
the quarter  ended  September  30,  2002,  our sales and  marketing  expenses in
personnel and marketing  programs  increased  $155,000 from the comparable prior
year period.

GENERAL  AND  ADMINISTRATIVE:  General  and  administrative  expenses  were $1.4
million for the three months ended  September 30, 2002, and $1.8 million for the
three months ended September 30, 2001, a decrease of approximately  $400,000. As
a percentage of sales,  general and administrative  expenses represented 14% and
20% for the three  months  ended  September  30,  2002 and  2001,  respectively.
Excluding $429,000 of general and administrative charges in the third quarter of
2001 related to severance and termination  matters,  the Company reduced its G&A
expenses, as a percentage of sales, from 15% to 14%.

AMORTIZATION  OF  INTANGIBLE  ASSETS AND  GOODWILL:  Amortization  of intangible
assets for each of the three months ended  September  30, 2002 and 2001 amounted
to  $160,000  and  $275,000,  respectively  and  is  related  primarily  to  the
amortization of the  identifiable  intangible  assets from the QCB and Biofluids
acquisitions.  The reduction in amortization in the current quarter  compared to
the quarter ended  September 30, 2001, is related to the  implementation  of FAS
142 which eliminated a significant amount of goodwill amortization.


                                       12





INTEREST INCOME:  Interest income for the three months ended September 30, 2002,
and  September  30, 2001,  was $21,000 and $85,000 which was related to interest
income on cash invested in short-term  securities  during each of the respective
quarters.

INCOME TAX EXPENSE:  The effective income tax rate and income tax amount for the
three months ending September 30, 2002 was 22% or $149,000. In the quarter ended
September 30, 2001, the Company  adjusted its  annualized  effective tax rate to
- -4%. As a result,  the Company  recorded a ($266,000)  tax benefit for the three
month period ended  September 30, 2001. The Company has benefited from R & D and
other tax  credits  which  when  applied  to the lower  income  for the  periods
presented  results  in a lower  effective  tax rate for the three  months  ended
September 30, 2001, compared to the three months ended September 30, 2002.

RESULTS OF OPERATIONS FOR THE NINE MONTHS ENDED SEPTEMBER 30, 2002

REVENUES:  Net sales for the nine months ended  September 30, 2002 were a record
$30.2 million,  an increase of $4.2 million,  or 16%, (15% after eliminating the
$204,000 positive impact of foreign exchange) compared to net sales for the nine
months ended  September 30, 2001.  The Company's  increased  sales and marketing
expenditures,  including increased sales personnel and marketing  programs,  and
its continued investment in research and development activities resulting in new
products for sale,  have been primary  drivers for sales growth in North America
and Europe.  For the nine months ended September 30, 2002, the Company  achieved
net sales  growth in North  America of 15% as compared to the nine months  ended
September 30, 2001.  European sales for the nine months ended September 30, 2002
increased 19% (16% in local currency),  as compared to the comparable prior year
period.  Sales in Japan and the rest of the world  increased  15%,  for the nine
months ended  September 30, 2002 as compared to the nine months ended  September
30, 2001.  Solidifying our relationship with our Japanese  distributor through a
new distributor agreement in 2001 and expanding our customer base in the rest of
the world have contributed to our 15% growth in Japan and the rest of the world.

GROSS PROFIT:  Gross profit margin for the nine months ended  September 30, 2002
was 57%, compared to 56% for the nine months ended September 30, 2001. The gross
profit  margin  was 1% higher  for the nine  months  ended  September  30,  2002
primarily due to the selling mix of products.

RESEARCH AND DEVELOPMENT:  Research and development  expense for the nine months
ended September 30, 2002 and 2001 were $4,362,000 and $2,930,000 and represented
14% and 11% of sales  respectively.  The  increase in research  and  development
expenses  for the nine months  ended  September  30,  2002 when  compared to the
comparable  prior year period  reflects the  Company's  investment in additional
personnel and materials in the cytokine and signal  transduction  research areas
with the goal of producing  additional novel and proprietary  products.  Through
September  30, 2002,  the Company has  increased  its  research and  development
capabilities by adding approximately 20 new research and development positions.

SALES AND  MARKETING:  Selling and marketing  expenses were $6.2 million for the
nine months ended  September 30, 2002 and $5.6 million for the nine months ended
September 30, 2001, respectively.  As a percentage of sales, sales and marketing
expenses  represented  21% for each of the nine months ended  September 30, 2002
and 2001. In the nine months ended  September 30, 2002,  our sales and marketing
expenses  in  personnel  and  marketing  programs  increased  $687,000  from the
comparable prior year period.

GENERAL  AND  ADMINISTRATIVE:  General  and  administrative  expenses  were $4.3
million for the nine months ended  September 30, 2002,  and $4.9 million for the
nine months ended September 30, 2001, a decrease of approximately $600,000. As a
percentage of sales, general and administrative expenses represented 14% and 19%
for the nine months ended September 30, 2002 and 2001,  respectively.  Excluding
$701,000 of net general and  administrative  charges which  occurred  during the
nine months ended September 30 2001 and were related to  non-recurring  employee
and legal matters,  the Company reduced its general and administrative  expenses
as a percentage of sales from 16% to 14%.

AMORTIZATION  OF  INTANGIBLE  ASSETS AND  GOODWILL:  Amortization  of intangible
assets for each of the nine months ended September 30, 2002 and 2001 amounted to
$481,000 and $824,000, respectively and is primarily related to the amortization
of the intangible assets from the QCB and Biofluids acquisitions.  The reduction
in amortization in the


                                       13





current nine months ended compared to the nine months ended  September 30, 2001,
is related  to the  implementation  of FAS 142 which  eliminated  a  significant
amount of goodwill amortization.

INTEREST  INCOME,  NET:  Interest income for the nine months ended September 30,
2002 and September 30, 2001,  was $82,000 and $330,000  respectively,  which was
related to interest income on cash invested in short-term securities during each
of the respective nine month periods.

INCOME TAX EXPENSE:  The effective income tax rate and income tax amount for the
nine months ended  September 30, 2002 was 22% or $381,000,  and -4% or ($30,000)
for the nine months ended September 30, 2001. The Company has benefited from R &
D and other tax credits  which when  applied to the lower income for the periods
presented  results  in a lower  effective  tax rate for the  nine  months  ended
September  30,  2002,  and an  income  tax  benefit  for the nine  months  ended
September 30, 2001.

CUMULATIVE  EFFECT OF  ACCOUNTING  CHANGE:  In the first  quarter  of 2002,  the
Company  recognized  a non-cash  charge,  net of  applicable  income  taxes,  of
$2,870,000  representing  the  cumulative  effect  of  a  change  in  accounting
principle  resulting from the implementation of FAS 142. The charge included the
write  off  of  goodwill  related  to  the  acquisition  of  Quality  Controlled
Biochemicals ("QCB") in December 1998. In the third quarter of 2002, the Company
received cash proceeds of $800,000 in an arbitration  settlement  related to its
1998  acquisition of QCB. This recovery,  shown net of legal fees and applicable
income taxes, totals $423,000 and is shown as a cumulative effect of a change in
accounting  principle  for the three months ended  September  30, 2002.  The net
impairment  charge for goodwill  resulting  from the adoption of FAS 142 for the
nine  months  ended  September  30,  2002  is  $2,447,000  and is  shown  in the
accompanying  condensed  consolidated  statement of  operations  as a cumulative
effect of an  accounting  change.  The effect of the  implementation  of FAS 142
reduced  amortization  of intangibles  for the nine months ended  September from
$824,000 to  $481,000.  With these net  charges,  the Company has recorded a net
income for the three  months ended  September  30, 2002 of $ 951,000 or $.09 per
diluted  share and a net loss for the nine months  ended  September  30, 2002 of
($1,097,000) or ($.11) per diluted share.


LIQUIDITY AND CAPITAL RESOURCES:

Cash and cash  equivalents as of September 30, 2002, of $5,798,000  decreased by
$3,673,000  from  $9,471,000 at December 31, 2001.  The decrease in cash was due
primarily  from a cash outlay of $4,611,000 for the repurchase of 782,000 shares
of the Company's common stock through its stock repurchase  program initiated in
October  2001.  Net cash provided from  operating  activities of $3,196,000  was
offset by  capital  expenditures  of  $2,632,000  and  financing  activities  of
$4,387,000.  Working capital, which is the excess of current assets over current
liabilities,  was  $16,285,000 at September 30, 2002, as compared to $19,000,000
at December 31, 2001, representing a decrease of $3,175,000.

In the nine months ended September 30, 2002, the Company received  $224,000 from
the issuance of common stock related to the exercise of stock options.

In  October of 2001,  the  Company  announced  that its Board of  Directors  had
approved a stock  repurchase  program.  The Board has  authorized the Company to
repurchase up to $5,000,000 of its common stock.  The repurchases are to be made
at the  discretion  of  management  and  can be  made  at any  time,  as  market
conditions warrant. The stock repurchase program will end June 30, 2003. On July
19, 2002,  the Company  amended the stock  repurchase  program and increased its
repurchase  commitment by $5 million to a total of $10 million.  As of September
30, 2002 and at November 8, 2002, the Company had repurchased  878,000 shares of
common stock and incurred a cash outlay totaling $5,279,000.

The Company has never paid  dividends  on common stock and has no plans to do so
in fiscal 2002. Our earnings will be retained for reinvestment in the business.

The  Company  expects to be able to meet its  future  cash and  working  capital
requirements for operations and capital additions  through  currently  available
funds  and  cash  generated  from  operations,  if any.  However,  we may  raise
additional  capital or secure debt financing from time to time to take advantage
of  favorable  conditions  in the  market or in  connection  with our  corporate
development activities.


                                       14





                                  RISK FACTORS

You  should  carefully  consider  the  following  risk  factors  and  all  other
information  contained  in this report  before  purchasing  shares of our common
stock.  Investing in our common stock  involves a high degree of risk. If any of
the following events or outcomes actually occur, our business, operating results
and financial  condition would likely suffer. As a result,  the trading price of
our common  stock could  decline,  and you may lose all or part of the money you
paid to purchase our common stock.

                          RISKS RELATED TO OUR BUSINESS

FAILURE TO MANAGE OUR GROWTH AND EXPANSION COULD IMPAIR OUR BUSINESS.

We  historically  have sought,  and will continue to seek, to increase our sales
and profitability  primarily through the acquisition or internal  development of
new product  lines,  additional  customers and new  businesses.  Our  historical
revenue growth is primarily  attributable  to our  acquisitions  and new product
development  and, to a lesser  extent,  to increased  revenues from our existing
products. We expect that future acquisitions,  if successfully consummated, will
create  increased  working  capital  requirements,  which will likely precede by
several  months any material  contribution  of an acquisition to our net income.
Our  ability  to  achieve  our  expansion  objectives  and to manage  our growth
effectively and profitably depends upon a variety of factors, including:

o    our ability to internally develop new products;

o    our ability to make profitable acquisitions;

o    integration of new facilities into existing operations;

o    hiring, training and retention of qualified personnel;

o    establishment of new  relationships or expansion of existing  relationships
     with customers and suppliers; and

o    availability of capital.

In addition,  the  implementation  of our growth strategy will place significant
strain on our administrative,  operational and financial resources and increased
demands on our financial systems and controls.  Our ability to manage our growth
successfully  will require us to continue to improve and expand these resources,
systems and controls.  If our management is unable to manage growth effectively,
our operating  results could be adversely  affected.  Moreover,  there can be no
assurance that our historic rate of growth will continue,  that we will continue
to successfully expand or that growth or expansion will result in profitability.

WE CANNOT GUARANTEE THAT OUR FUTURE ACQUISITIONS WILL BE SUCCESSFUL.

We compete for acquisition and expansion opportunities with companies which have
significantly  greater financial and management  resources than us. There can be
no assurance  that  suitable  acquisition  or investment  opportunities  will be
identified,  that any of these  transactions  can be  consummated,  or that,  if
acquired,  these new  businesses can be integrated  successfully  and profitably
into our  operations.  These  acquisitions  and  investments  may also require a
significant  allocation of resources,  which will reduce our ability to focus on
the other portions of our business,  including many of the factors listed in the
prior risk factor.

REDUCTION  OR DELAYS IN  RESEARCH  AND  DEVELOPMENT  BUDGETS  AND IN  GOVERNMENT
FUNDING MAY NEGATIVELY IMPACT OUR SALES.

Our customers include researchers at pharmaceutical and biotechnology companies,
academic institutions and government and private  laboratories.  Fluctuations in
the  research  and   development   budgets  of  these   researchers   and  their
organizations  could have a  significant  effect on the demand for our products.
Research and development


                                       15





budgets  fluctuate due to numerous  factors that are outside our control and are
difficult  to  predict,  including  changes  in  available  resources,  spending
priorities and institutional budgetary policies. Our business could be seriously
damaged by any  significant  decrease in life sciences  research and development
expenditures   by   pharmaceutical   and   biotechnology   companies,   academic
institutions or government and private laboratories.

A  significant  portion  of our  sales  has been to  researchers,  universities,
government  laboratories and private foundations whose funding is dependent upon
grants from government  agencies such as the U.S. National  Institutes of Health
(the "NIH") and similar domestic and international agencies.  Although the level
of research  funding has  increased  during the past  several  years,  we cannot
assure  that this trend  will  continue.  Government  funding  of  research  and
development is subject to the political  process,  which is inherently fluid and
unpredictable.  Our revenues may be adversely  affected if our  customers  delay
purchases as a result of  uncertainties  surrounding  the approval of government
budget proposals.  Also,  government  proposals to reduce or eliminate budgetary
deficits  have  sometimes  included  reduced  allocations  to the NIH and  other
government agencies that fund research and development  activities.  A reduction
in government  funding for the NIH or other government  research  agencies could
seriously damage our business.

Many of our customers  receive funds from approved grants at particular times of
the year,  as determined  by the federal  government.  Grants have, in the past,
been frozen for extended periods or have otherwise become unavailable to various
institutions  without advance  notice.  The timing of the receipt of grant funds
affects the timing of purchase  decisions by our customers and, as a result, can
cause fluctuations in our sales and operating results.

WE RELY ON RAW MATERIALS AND SPECIALIZED EQUIPMENT FOR OUR MANUFACTURING,  WHICH
WE MAY NOT ALWAYS BE ABLE TO OBTAIN ON FAVORABLE TERMS.

Our manufacturing  process relies on the continued  availability of high-quality
raw  materials  and  specialized  equipment.  It is  possible  that a change  in
vendors,  or in the quality of the raw  materials  supplied to us, could have an
adverse impact on our manufacturing process and, ultimately,  on the sale of our
finished  products.  We have from time to time  experienced  a disruption in the
quality or availability of key raw materials,  which has created minor delays in
our ability to fill orders for specific test kits. This could occur again in the
future,  resulting in significant delays, and could have a detrimental impact on
the sale of our products and our results of operations.  In addition, we rely on
highly  specialized  manufacturing  equipment  that if damaged or disabled could
adversely   affect  our  ability  to  manufacture  our  products  and  therefore
negatively impact our business.

OUR ABILITY TO RAISE THE CAPITAL NECESSARY TO EXPAND OUR BUSINESS IS UNCERTAIN.

In the future,  in order to expand our business through internal  development or
acquisitions,  we may need to raise substantial  additional funds through equity
or  debt  financings,  research  and  development  financings  or  collaborative
relationships.  However,  this  additional  funding may not be available  or, if
available,  it  may  not be  available  on  economically  reasonable  terms.  In
addition,  any additional funding may result in significant dilution to existing
stockholders. If adequate funds are not available, we may be required to curtail
our operations or obtain funds through  collaborative  partners that may require
us to release material rights to our products.

OUR RESEARCH AND DEVELOPMENT EFFORTS FOR NEW PRODUCTS MAY BE UNSUCCESSFUL.

We incur significant  research and development  expenses to develop new products
and  technologies.  There  can be no  assurance  that any of these  products  or
technologies  will be  successfully  developed  or that  if  developed,  will be
commercially   successful.   In  the  event   that  we  are  unable  to  develop
commercialized  products  from our  research and  development  efforts or we are
unable or  unwilling  to  allocate  amounts  beyond  our  currently  anticipated
research and  development  investment,  we could lose our entire  investment  in
these new  products  and  technologies.  Any failure to  translate  research and
development expenditures into successful new product introductions could have an
adverse effect on our business.


                                       16





FAILURE TO LICENSE NEW TECHNOLOGIES COULD IMPAIR OUR NEW PRODUCT DEVELOPMENT.

Our business model of providing products to researchers  working on a variety of
genetic projects requires us to develop a wide spectrum of products. To generate
broad product lines it is advantageous to sometimes  license  technologies  from
others rather than depending  exclusively on our own employees.  As a result, we
believe our ability to license new  technologies  from third parties is and will
continue to be important to our ability to offer new products.

In  addition,  from time to time we are notified or become aware of patents held
by third parties that are related to  technologies we are selling or may sell in
the future.  After a review of these patents,  we may decide to obtain a license
for these  technologies  from these third parties or  discontinue  the products.
There  can be no  assurance  that we will be able to  continue  to  successfully
identify new technologies  developed by others.  Even if we are able to identify
new  technologies  of  interest,  we may not be able to  negotiate  a license on
favorable terms, or at all. If we lose the rights to patented technology, we may
need to discontinue  selling certain  products or redesign our products,  and we
may  lose  a  competitive  advantage.  Potential  competitors  could  in-license
technologies  that we fail to license and potentially erode our market share for
certain   products.    Our   licenses    typically   subject   us   to   various
commercialization,  sublicensing,  minimum payment, and other obligations. If we
fail to comply with these  requirements,  we could lose important rights under a
license. In addition, certain rights granted under the license could be lost for
reasons  out of our  control.  For  example,  the  licensor  could  lose  patent
protection for a number of reasons, including invalidity of the licensed patent.
We do not always receive  significant  indemnification  from a licensor  against
third party claims of intellectual property infringement.

We are  currently in the process of  negotiating  several of these  licenses and
expect that we will also negotiate these types of licenses in the future.  There
can be no  assurances  that  we will be able  to  negotiate  these  licenses  on
favorable terms, or at all.

OUR FUTURE SUCCESS  DEPENDS ON THE TIMELY  INTRODUCTION  OF NEW PRODUCTS AND THE
ACCEPTANCE OF THESE NEW PRODUCTS IN THE MARKETPLACE.

Our ability to gain access to technologies  needed for new products and services
also  depends  in  part  on  our  ability  to  convince  licensors  that  we can
successfully  commercialize  their inventions.  We cannot assure that we will be
able to continue to identify new  technologies  developed by others.  Even if we
are  able  to  identify  new  technologies  of  interest,  we may not be able to
negotiate a license on favorable terms, or at all.

IF WE FAIL TO INTRODUCE  NEW  PRODUCTS,  OR OUR NEW PRODUCTS ARE NOT ACCEPTED BY
POTENTIAL CUSTOMERS, WE MAY LOSE MARKET SHARE.

Rapid  technological  change and frequent new product  introductions are typical
for the markets we serve.  Our future success will depend in part on continuous,
timely development and introduction of new products that address evolving market
requirements.   We  believe  successful  new  product  introductions  provide  a
significant  competitive  advantage because customers make an investment of time
in  selecting  and  learning to use a new  product,  and then are  reluctant  to
switch. To the extent we fail to introduce new and innovative  products,  we may
lose market share to our  competitors,  which will be difficult or impossible to
regain.  Any inability,  for  technological  or other reasons,  to  successfully
develop and  introduce  new products  could reduce our growth rate or damage our
business.

In the past we have  experienced,  and are likely to  experience  in the future,
delays in the development and introduction of products. We cannot assure that we
will keep pace with the rapid rate of change in life sciences research,  or that
our new products will  adequately  meet the  requirements  of the marketplace or
achieve market  acceptance.  Some of the factors  affecting market acceptance of
new products include:

o    availability, quality and price relative to competitive products;

o    the timing of introduction of the product relative to competitive products;

o    customers' opinion of the products utility;


                                       17





o    ease of use;

o    consistency with prior practices;

o    scientists' opinion of the product's usefulness;

o    citation of the product in published research; and

o    general trends in life sciences research.

The  expenses  or  losses  associated  with  unsuccessful   product  development
activities  or lack of market  acceptance of our new products  could  materially
adversely affect our business,  operating results and financial  condition.  The
development,  introduction  and marketing of innovative  products in our rapidly
evolving markets will require significant sustained investment. We cannot assure
that cash from  operations  or other  sources will be  sufficient  to meet these
ongoing requirements.

FAILURE TO ATTRACT AND RETAIN  QUALIFIED  SCIENTIFIC OR PRODUCTION  PERSONNEL OR
LOSS OF KEY MANAGEMENT OR KEY PERSONNEL COULD HURT OUR BUSINESS.

Recruiting  and  retaining  qualified  scientific  and  production  personnel to
perform research and development  work and product  manufacturing is critical to
our success.  Because the industry in which we compete is very  competitive,  we
face significant  challenges  attracting and retaining this qualified  personnel
base.  Although  we believe we have been and will be able to attract  and retain
these  personnel,  there can be no assurance that we will be able to continue to
successfully  attract qualified personnel.  In addition,  our anticipated growth
and expansion into areas and activities requiring additional expertise,  such as
clinical testing,  government approvals,  production and marketing, will require
the addition of new  management  personnel  and the  development  of  additional
expertise by existing  management  personnel.  The failure to attract and retain
these personnel or,  alternatively,  to develop this expertise  internally would
adversely  affect  our  business.  We  generally  do not enter  into  employment
agreements  requiring  these  employees  to continue in our  employment  for any
period of time.

Our success also will continue to depend to a significant  extent on the members
of our management team and, in particular,  on our Chief  Executive  Officer and
President,  Leonard M.  Hendrickson.  We do not maintain any "key man" insurance
policies  regarding any of these  individuals.  We may not be able to retain the
services of our  executive  officers  and key  personnel  or attract  additional
qualified  members to  management  in the  future.  The loss of  services of Mr.
Hendrickson,  or of any of our other key  management or employees,  could have a
material adverse effect upon our business.

MANY OF OUR  CUSTOMERS  ARE  OBTAINING  OUR  PRODUCTS  THROUGH NEW  DISTRIBUTION
CHANNELS AND METHODS THAT MAY  ADVERSELY  IMPACT OUR RESULTS OF  OPERATIONS  AND
FINANCIAL CONDITION.

A number of our customers  have developed  purchasing  initiatives to reduce the
number of vendors they purchase  from in order to lower their supply  costs.  In
some cases, these customers have established  agreements with large distributors
which  include  discounts  and the  distributors'  direct  involvement  with the
purchasing process.  For similar reasons,  many larger customers,  including the
federal  government,  have  special  pricing  arrangements,   including  blanket
purchase  agreements.  These  agreements may limit our pricing  flexibility with
respect to our products,  which could adversely  impact our business,  financial
condition and results of operations. In addition, although we accept and process
some orders  through our Internet  website,  we also  implement  sales through a
third  party  Internet  vendor.   Internet  sales  through  third  parties  will
negatively  impact our gross margins because we pay commission on these Internet
sales. On the other hand, if we do not enter into  arrangements with third-party
e-commerce  providers,  we may lose  customers  who prefer to purchase  products
using these Web sites. Our business may be harmed as a result of these Web sites
or other sales methods which may be developed in the future.

                                       18





WE RELY ON INTERNATIONAL SALES, WHICH ARE SUBJECT TO ADDITIONAL RISKS.

International  sales accounted for  approximately 41% and 41% of our revenues in
the first nine months of 2002 and 2001, respectively. International sales can be
subject  to many  inherent  risks that are  difficult  or  impossible  for us to
predict or control, including:

o    unexpected changes in regulatory requirements and tariffs;

o    difficulties  and costs  associated  with in staffing and managing  foreign
     operations, including foreign distributor relationships;

o    longer accounts receivable collection cycles in certain foreign countries;

o    adverse economic or political changes;

o    more limited  protection for  intellectual  property in some  countries;

o    changes in our international distribution network and direct sales force;

o    potential  trade  restrictions,  exchange  controls  and  import and export
     licensing requirements;

o    problems in collecting accounts receivable; and

o    potentially adverse tax consequences of overlapping tax structure.

We intend to continue to generate  revenues  from sales outside North America in
the future.  Future  distribution of our products outside North America also may
be subject to greater governmental regulation. These regulations,  which include
requirements for approvals or clearance to market,  additional time required for
regulatory  review and sanctions  imposed for  violations,  as well as the other
risks indicated in the bullets listed above, vary by country. We may not be able
to obtain  regulatory  approvals in the countries in which we currently sell our
products  or in  countries  where we may sell our  products  in the  future.  In
addition,  we may be required to incur significant costs in obtaining  necessary
regulatory  approvals.  Failure to obtain necessary  regulatory approvals or any
other failure to comply with regulatory  requirements could result in a material
reduction in our revenues and earnings.

We also  depend  on  third-party  distributors  for a  material  portion  of our
international sales. If we lose or suffer any significant  reduction in sales to
any material distributor, our business could be materially adversely affected.

In addition,  approximately  26% of our sales in the nine months ended September
30, 2002,  were made in foreign  currencies,  primarily  the Euro. A significant
portion of the foreign currencies in which we conduct our business is currently,
or may in the future be,  denominated  in Euros.  We are not  certain  about the
future  effect of the Euro on our  business,  financial  condition or results of
operations.  In the past,  gains and losses on the  collection  of our  accounts
receivable  arising from  international  operations have contributed to negative
fluctuations in our results of operations. In general, increases in the exchange
rate of the United  States  dollar to foreign  currencies  cause our products to
become  relatively more expensive to customers in those countries,  leading to a
reduction in sales or profitability in some cases. We historically have not, and
currently  are not,  using  hedging  transactions  or other  means to reduce our
exposure to fluctuations in the value of the United States dollar as compared to
the foreign currencies in which many of our sales are made.

OUR OPERATING RESULTS MAY FLUCTUATE.

Our operating results may vary significantly quarter to quarter and from year to
year as a result of a variety of factors. These factors include:

o    level of demand for our products;


                                       19





o    changes in our customer and product mix;

o    timing of acquisitions and investments in infrastructure;

o    competitive conditions;

o    timing and extent of intellectual property litigation;

o    exchange rate fluctuations; and

o    general economic conditions.

We  believe  that  quarterly  comparisons  of  our  financial  results  may  not
necessarily  be  meaningful  and should not be relied upon as an  indication  of
future  performance.  Additionally,  if our  operating  results  in one or  more
quarters do not meet the expectations of security analysts or others,  the price
of our common  stock  could be  materially  adversely  affected.  Our  continued
investment in product  development  and sales and  marketing  are  significantly
ongoing expenses. If revenue in a particular period falls short of expectations,
we may not be able to reduce  significantly  our  expenditures  for that period,
which would materially adversely affect the operating results for that period.

WE MAY BE UNABLE TO PROTECT OUR TRADEMARKS, TRADE SECRETS AND OTHER INTELLECTUAL
PROPERTY RIGHTS THAT ARE IMPORTANT TO OUR BUSINESS.

We regard our  trademarks,  trade secrets and other  intellectual  property as a
component of our success.  We rely on trademark law and trade secret  protection
and  confidentiality  and/or  license  agreements  with  employees,   customers,
partners and others to protect our intellectual  property.  Effective  trademark
and trade secret  protection  may not be available in every country in which our
products are  available.  We cannot be certain that we have taken adequate steps
to protect our intellectual property, especially in countries where the laws may
not  protect  our  rights as fully as in the United  States.  In  addition,  our
third-party  confidentiality  agreements can be breached and, if they are, there
may not be an  adequate  remedy  available  to us. If our trade  secrets  become
known, we may lose our competitive position.

INTELLECTUAL PROPERTY OR OTHER LITIGATION COULD HARM OUR BUSINESS.

Litigation regarding patents and other intellectual property rights is extensive
in the biotechnology  industry. We are aware that patents have been applied for,
and in some  cases  issued to others,  claiming  technologies  that are  closely
related to ours. As a result,  and in part due to the  ambiguities  and evolving
nature  of  intellectual  property  law,  we  periodically  receive  notices  of
potential  infringement  of  patents  held by others.  Although  to date we have
successfully  resolved these types of claims, we may not be able to do so in the
future.

In the event of an intellectual  property dispute, we may be forced to litigate.
This  litigation  could  involve  proceedings  declared  by the U.S.  Patent and
Trademark Office or the International  Trade Commission,  as well as proceedings
brought directly by affected third parties. Intellectual property litigation can
be extremely expensive,  and these expenses,  as well as the consequences should
we not prevail, could seriously harm our business.

If a third party claimed an intellectual property right to technology we use, we
might need to  discontinue  an  important  product or  product  line,  alter our
products  and  processes,  pay  license  fees or  cease  our  affected  business
activities.  Although  we might under  these  circumstances  attempt to obtain a
license to this intellectual  property, we may not be able to do so on favorable
terms, or at all.

In addition to intellectual property litigation,  other substantial,  complex or
extended  litigation could result in large expenditures by us and distraction of
our management. For example, lawsuits by employees, stockholders,  collaborators
or  distributors  could be very costly and  substantially  disrupt our business.
Disputes from time to time with companies or individuals are not uncommon in our
industry,  and we cannot  assure you that we will always be able to resolve them
out of court.


                                       20





ACCIDENTS RELATED TO HAZARDOUS MATERIALS COULD ADVERSELY AFFECT OUR BUSINESS.

Portions  of  our  operations  require  the  controlled  use  of  hazardous  and
radioactive materials. Although we believe our safety procedures comply with the
standards prescribed by federal, state, local and foreign regulations,  the risk
of  accidental  contamination  of property or injury to  individuals  from these
materials cannot be completely eliminated. In the event of an accident, we could
be liable for any damages that result, which could seriously damage our business
and results of operations.

OUR SALES ARE SUBJECT TO  SEASONALITY,  WHICH MEANS THAT WE HAVE LESS REVENUE IN
SOME MONTHS.

We  experience  a slowing  of sales in  Europe  during  the  summer  months  and
worldwide during the Christmas holidays.  Generally, our fourth quarter revenues
are lower than our revenues in each of the first three  quarters of the year. We
believe  that  period to period  comparisons  of our  operating  results may not
necessarily be reliable indicators of our future performance.  It is likely that
in some future period our operating  results will not meet expectations or those
of public market analysts,  which could result in reductions in the market price
of our common stock.

POTENTIAL  PRODUCT  LIABILITY  CLAIMS COULD  AFFECT OUR EARNINGS AND  FINANCIAL
CONDITION.

We face a potential risk of liability claims based on our products and services,
and we have faced such claims in the past. We carry product liability  insurance
coverage  which is  limited  in scope  and  amount  but which we  believe  to be
adequate.  We cannot assure you, however,  that we will be able to maintain this
insurance at reasonable cost and on reasonable terms. We also cannot assure that
this insurance will be adequate to protect us against a product liability claim,
should one arise.

THE  LABOR  LAWS  APPLICABLE  TO  OUR  EMPLOYEES  IN  EUROPE  MAY  RESTRICT  THE
FLEXIBILITY OF OUR MANAGEMENT.

As of October 31, 2002, 66 of our 288 employees  worked for our BioSource Europe
subsidiary,  which is located in Nivelles, Belgium. As a result of Belgian labor
laws,  we are  required  to make  specified  severance  payments in the event we
terminate a European employee. Accordingly, our management may be limited by the
application of the Belgian labor laws in the  determination  of staffing levels,
and may have less flexibility in making such determinations than our competitors
whose employees are not subject to similar labor laws.

                       RISKS ASSOCIATED WITH OUR INDUSTRY

THE BIOMEDICAL  RESEARCH PRODUCTS  INDUSTRY IS VERY  COMPETITIVE,  AND WE MAY BE
UNABLE TO CONTINUE TO COMPETE EFFECTIVELY IN THIS INDUSTRY IN THE FUTURE.

We are engaged in a segment of the biomedical research products industry that is
highly  competitive.  We compete with many other  suppliers and new  competitors
continue  to enter the  markets.  Many of our  competitors,  both in the  United
States and  elsewhere,  are major  pharmaceutical,  chemical  and  biotechnology
companies,  and  many of them  have  substantially  greater  capital  resources,
marketing  experience,  research and development  staffs, and facilities than we
do. Any of these  companies  could succeed in developing  products that are more
effective  than the  products  that we have or may  develop and may also be more
successful  than us in producing and marketing  their  products.  We expect this
competition to continue and intensify in the future.  Competition in our markets
is primarily driven by:

o    product performance, features and liability;

o    price;

o    timing of product introductions;

o    ability  to  develop,   maintain  and  protect  proprietary   products  and
     technologies;

o    sales and distribution capabilities;


                                       21





o    technical support and service;

o    brand royalty;

o    applications support; and

o    breadth of product line.

If a competitor develops superior  technology or cost-effective  alternatives to
our products, our business,  financial condition and results of operations could
be materially adversely affected.

Our industry has also seen substantial  consolidation in recent years, which has
led to the creation of  competitors  with  greater  financial  and  intellectual
property resources than us. In addition, we believe that the success that others
have had in our industry will attract new  competitors.  Some of our current and
future  competitors  also may cooperate to better compete against us. We may not
be able to compete  effectively  against  these  current or future  competitors.
Increased competition could result in price reductions for our products, reduced
margins  and loss of market  share,  any of which  could  adversely  impact  our
business, financial condition and results of operations.

AS A  RESULT  OF  CONSOLIDATION  IN THE  PHARMACEUTICAL  INDUSTRY,  WE MAY  LOSE
EXISTING CUSTOMERS OR HAVE GREATER DIFFICULTY OBTAINING NEW CUSTOMERS.

In recent  years,  the  United  States  pharmaceutical  industry  has  undergone
substantial  consolidation.  As part of many  business  combinations,  companies
frequently  reduce the number of suppliers  used and we may not be selected as a
supplier  after  any  business  combination.   Further,   mergers  or  corporate
consolidations  in the  pharmaceutical  industry could cause us to lose existing
customers and potential  future  customers,  which could have a material adverse
effect on our business, financial condition and results of operations.

WE ARE CURRENTLY SUBJECT TO GOVERNMENT REGULATION.

Our business is currently  subject to regulation,  supervision  and licensing by
federal,  state and local governmental  authorities.  Also, from time to time we
must expend  resources  to comply  with newly  adopted  regulations,  as well as
changes in existing regulations. If we fail to comply with these regulations, we
could be subject to disciplinary actions or administrative  enforcement actions.
These actions could result in penalties, including fines.

                     RISKS ASSOCIATED WITH OUR COMMON STOCK

OUR STOCK PRICE HAS BEEN VOLATILE.

Our common  stock is quoted on the Nasdaq  National  Market,  and there has been
substantial  volatility  in the market  price of our common  stock.  The trading
price of our common stock has been,  and is likely to continue to be, subject to
significant fluctuations due to a variety of factors, including:

o    fluctuations in our quarterly operating and earnings per share results;

o    the gain or loss of significant contracts;

o    loss of key personnel;

o    announcements  of  technological  innovations  or new products by us or our
     competitors;

o    delays in the development and introduction of new products;

o    legislative or regulatory changes;

o    general trends in the industry;


                                       22





o    recommendations  and/or changes in estimates by equity and market  research
     analysts;

o    biological or medical discoveries;

o    disputes and/or developments  concerning  intellectual property,  including
     patents and litigation matters;

o    public concern as to the safety of new technologies;

o    sales of common stock of existing holders;

o    securities class action or other litigation;

o    developments  in our  relationships  with current or future  customers  and
     suppliers; and

o    general economic conditions, both in the United States and abroad.

As a result of these factors,  and  potentially  others,  the sales price of our
common  stock has ranged  from  $2.41 to $32.00 per share from  January 1, 1998,
through  November  8, 2002,  and from  $4.89 to $8.20 per share from  January 1,
2002, through November 8, 2002.

In  addition,  the stock  market in general has  experienced  extreme  price and
volume  fluctuations that have affected the market price of our common stock, as
well as the stock of many biotechnology companies. Often, price fluctuations are
unrelated to operating  performance  of the  specific  companies  whose stock is
affected.

In the past,  following periods of volatility in the market price of a company's
stock,  securities  class action  litigation  has  occurred  against the issuing
company.  If we were subject to this type of litigation in the future,  we could
incur  substantial  costs and a  diversion  of our  management's  attention  and
resources, each of which could have a material adverse effect on our revenue and
earnings.  Any  adverse  determination  in this type of  litigation  could  also
subject us to significant liabilities.

ANTI-TAKEOVER  PROVISIONS IN OUR GOVERNING  DOCUMENTS AND UNDER  APPLICABLE  LAW
COULD IMPAIR THE ABILITY OF A THIRD PARTY TO TAKE OVER OUR COMPANY.

We are subject to various  legal and  contractual  provisions  that may impede a
change in our control, including the following:

o    our  adoption of a  stockholders'  rights  plan,  which could result in the
     significant  dilution  of the  proportionate  ownership  of any person that
     engages in an unsolicited attempt to take over our company; and

o    the ability of our board of  directors  to issue  additional  shares of our
     preferred stock,  which shares may be given superior  voting,  liquidation,
     distribution and other rights as compared to our common stock.

These   provisions,   as  well  as  other   provisions  in  our  certificate  of
incorporation  and bylaws and under the Delaware General  Corporations  Law, may
make it more  difficult  for a third party to acquire our  company,  even if the
acquisition  attempt was at a premium  over the market value of our common stock
at that time.

Our principal  stockholders  and management own a significant  percentage of our
capital  stock  and  will be able to  exercise  significant  influence  over our
affairs.  Our executive  officers,  directors and  principal  stockholders  will
continue to beneficially own 33.8% of our outstanding  common stock,  based upon
the  beneficial  ownership  of our  common  stock as of  November  8,  2002.  In
addition,  these same persons also hold options to acquire  additional shares of
our common stock,  which may increase their  percentage  ownership of the common
stock further in the future. Accordingly, these stockholders:

o    will be able to  significantly  influence the  composition  of our board of
     directors;


                                       23





o    will significantly  influence all matters requiring  stockholder  approval,
     including change of control transactions; and

o    will continue to have significant influence over our business.

This  concentration  of  ownership  of our common stock could have the effect of
delaying or  preventing  a change of control of us or otherwise  discouraging  a
potential  acquirer from  attempting to obtain control of us. This in turn could
have a negative  effect on the market price of our common  stock.  It could also
prevent our  stockholders  from  realizing a premium over the market  prices for
their shares of common stock.

OUR PRINCIPAL  STOCKHOLDERS  AND MANAGEMENT OWN A SIGNIFICANT  PERCENTAGE OF OUR
CAPITAL  STOCK  AND  WILL BE ABLE TO  EXERCISE  SIGNIFICANT  INFLUENCE  OVER OUR
AFFAIRS.

Our executive officers,  directors and principal  stockholders  beneficially own
approximately  33.8% of our outstanding  common stock, based upon the beneficial
ownership  of our  common  stock as of  November  8,  2002.  As a result,  these
stockholders,  if they act  together,  could exert  substantial  influence  over
matters requiring stockholder approval,  including the election of directors and
approval of mergers and other  significant  corporate  transactions.  The voting
power of such persons may have the effect of delaying, preventing or deterring a
change in control, and could affect the market price of our common stock.

ABSENCE OF DIVIDENDS COULD REDUCE OUR ATTRACTIVENESS TO YOU.

Some  investors  favor  companies that pay  dividends,  particularly  in general
downturns in the stock market. We have never declared or paid any cash dividends
on our common  stock.  We  currently  intend to retain any future  earnings  for
funding growth and we do not currently  anticipate  paying cash dividends on our
common stock in the foreseeable  future.  Because we may not pay dividends,  the
return on this investment likely depends on selling this stock at a profit.


ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES OF MARKET RISK:

We conduct business in various foreign  currencies and are therefore  subject to
the  transaction  exposures  that arise from  foreign  exchange  rate  movements
between the dates that foreign currency  transactions are initiated and the date
that they are converted.  We are also subject to certain  exposures arising from
the  translation  and  consolidation  of the  financial  results of our  foreign
subsidiaries.  There can be no  assurance  that  actions  taken to  manage  such
exposures  will  continue to be  successful  or that future  changes in currency
exchange  rates will not have a material  impact on our future cash  collections
and operating results.  We do not currently hedge either our transaction risk or
our economic risk.


ITEM 4. CONTROLS AND PROCEDURES

EVALUATION OF CONTROLS AND PROCEDURES

We maintain  disclosure controls and procedures which we have designed to ensure
that material  information related to BioSource  International,  Inc., including
our consolidated  subsidiaries,  is disclosed in our public filings on a regular
basis. In response to recent legislation and proposed  regulations,  we reviewed
our internal control  structure and our disclosure  controls and procedures.  We
believe our  pre-existing  disclosure  controls and  procedures  are adequate to
enable us to comply with our disclosure obligations.

Within 90 days prior to the  filing of this  report,  members  of the  Company's
management,  including the Company's President and Chief Executive Officer,  Len
Hendrickson,   and  Chief  Financial  Officer,   Charles  Best,   evaluated  the
effectiveness of the design and operation of the Company's  disclosure  controls
and  procedures.  Based  upon that  evaluation,  Mr.  Hendrickson  and Mr.  Best
concluded that the Company's disclosure controls and procedures are effective in
causing material information to be recorded, processed,  summarized and reported
by management of the


                                       24





Company on a timely basis and to ensure that the quality and  timeliness  of the
Company's public disclosures complies with its SEC disclosure obligations.

CHANGES IN CONTROLS AND PROCEDURES

         There were no significant changes in the Company's internal controls or
in other factors that could  significantly  affect these internal controls after
the date of our most recent evaluation.


                                       25





                                     PART II

                                OTHER INFORMATION
ITEM 1.  LEGAL PROCEEDINGS

In June of 2000,  the former  shareholders  of QCB  commenced a AAA  arbitration
proceeding  against us seeking the recovery of escrowed  funds from the purchase
of QCB that were  withheld  from the  purchase  price paid by us as security for
claims we might  discover after  closing.  We filed a  counterclaim  against the
former shareholders of QCB, including Dr. Fishman, in the arbitration to recover
damages  management  believes we suffered in connection  with  inaccuracies  in,
and/or breaches of the representations and warranties contained in, the original
Stock  Purchase  Agreement  for  QCB  executed  on  December  9,  1998.  In  our
counterclaim,  we sought to recover  $1,347,000  of escrowed  funds.  On July 2,
2002,  we settled  the  arbitration  and all related  claims  against the former
shareholders  of QCB and Dr.  Fishman in  consideration  of the payment to us of
$800,000  from the  escrowed  funds.  The  remaining  funds held in escrow  were
released to the former  shareholders  of QCB. This  settlement,  net of attorney
fees  and  income  taxes,  is  considered  to be a  reduction  of  the  goodwill
originally  recorded in the acquisition of QCB. That goodwill was written off as
a cumulative  effect of accounting  change in the adoption of FASB Statement No.
142 during the first  quarter of 2002.  The  settlement  was accounted for as an
adjustment  to the  cumulative  effect of  accounting  change  during  the third
quarter of 2002.

The Company is involved in various  other claims and lawsuits  incidental to its
business. In the opinion of management,  these claims and suits in the aggregate
will not  materially  affect the  financial  position,  results of operations or
liquidity of the Company.

ITEM 2.  CHANGE IN SECURITIES AND USE OF PROCEEDS
         None

ITEM 3.  DEFAULTS UPON SENIOR SECURITIES
         None.

ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

               On July  19,  2002,  the  Company  held  its  Annual  Meeting  of
          Stockholders.  At the  annual  meeting,  there were  9,638,863  shares
          entitled to vote and 9,594,580  shares were represented at the meeting
          in  person or by proxy.  The  following  sets  forth the  identity  of
          directors  elected for one year and until their respective  successors
          have been  elected.  In  addition,  the  results  of the voting on the
          ratification of appointment of the Company's auditors are included:

                                                       For            Withheld
                                                       ---            --------
               1.  Election of directors
                      Jean-Pierre L. Conte          9,552,740          41,840
                      Leonard M. Hendrickson        8,599,731         994,849
                      David J. Moffa                9,549,427          45,153
                      John R. Overturf, Jr.         9,548,227          46,353
                      Robert D. Weist               9,541,227          53,353
                      Robert J. Weltman             9,552,894          41,686


                                                   For       Against     Abstain
                                                   ---       -------     -------

               2.  Ratification of Auditors     9,576,123     9,630       8,827

ITEM 5.  OTHER INFORMATION
         None.


                                       26





ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K

         (a) Exhibits
                  Exhibit 99.1   Certificates of our Chief Executive Officer and
                                 Chief Financial Officer pursuant to Section 906
                                 of the Sarbanes-Oxley Act of 2002.

         (b) Reports on Form 8-K
                  The  Company  filed a  Current  Report on Form 8-K on July 24,
                  2002,   reporting  the   issuance's  of  two  press   releases
                  announcing  the  Company's  financial  results  for the second
                  quarter of fiscal year 2002,  and  announcing  an amendment to
                  the Company's current stock repurchase program, respectively.


                                       27





                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended,
the  registrant  has duly  caused  this report to be signed on its behalf by the
undersigned thereunto duly authorized.




                                              BIOSOURCE INTERNATIONAL, INC.
                                                      (Registrant)




Date:  November 11, 2002                        /s/ LEONARD M. HENDRICKSON
                                                --------------------------
                                                   Leonard M. Hendrickson
                                                   President and
                                                   Chief Executive Officer




Date:  November 11, 2002                        /s/ CHARLES C. BEST
                                                -------------------
                                                   Charles C. Best
                                                   Executive Vice President and
                                                   Chief Financial Officer


                                       28





                        Certification of CEO Pursuant to
                 Securities Exchange Act Rules 13a-14 and 15d-14
                             as Adopted Pursuant to
                  Section 302 of the Sarbanes-Oxley Act of 2002


I, Leonard M. Hendrickson certify that:

         1. I have  reviewed  this  quarterly  report on Form 10-Q for the three
months ended September 30, 2002;

         2. Based on my knowledge,  this  quarterly  report does not contain any
untrue  statement of a material fact or omit to state a material fact  necessary
to make the  statements  made,  in light of the  circumstances  under which such
statements  were made, not misleading with respect to the period covered by this
quarterly report;

         3. Based on my knowledge, the financial statements, and other financial
information  included in this quarterly  report,  fairly present in all material
respects the financial  condition,  results of operations  and cash flows of the
registrant as of, and for, the periods presented in this quarterly report;

         4. The registrant's other certifying officers and I are responsible for
establishing and maintaining  disclosure  controls and procedures (as defined in
Exchange Act Rules 13a-14 and 15d-14) for the registrant and we have:

                  a) designed such disclosure  controls and procedures to ensure
that material information relating to the registrant, including its consolidated
subsidiaries, is made known to us by others within those entities,  particularly
during the period in which this quarterly report is being prepared;

                  b) evaluated the effectiveness of the registrant's  disclosure
controls and  procedures as of a date within 90 days prior to the filing date of
this quarterly report (the "Evaluation Date"); and

                  c) presented in this quarterly  report our  conclusions  about
the  effectiveness  of the  disclosure  controls  and  procedures  based  on our
evaluation as of the Evaluation Date;

         5. The  registrant's  other  certifying  officers and I have disclosed,
based on our most recent evaluation,  to the registrant's auditors and the audit
committee  of  registrant's  board  of  directors  (or  persons  performing  the
equivalent function):

                  a) all significant  deficiencies in the design or operation of
internal  controls  which could  adversely  affect the  registrant's  ability to
record, process, summarize and report financial data and have identified for the
registrant's auditors any material weaknesses in internal controls; and

                  b)  any  fraud,   whether  or  not  material,   that  involves
management or other  employees who have a significant  role in the  registrant's
internal controls; and

         6. The registrant's  other certifying  officers and I have indicated in
this quarterly report whether or not there were significant  changes in internal
controls or in other factors that could  significantly  affect internal controls
subsequent to the date of our most recent  evaluation,  including any corrective
actions with regard to significant deficiencies and material weaknesses.

Date: November 11, 2002
                                           /s/LEONARD M. HENDRICKSON
                                           -------------------------------------
                                           Leonard M. Hendrickson
                                           President and Chief Executive Officer


                                       29





                        Certification of CFO Pursuant to
                 Securities Exchange Act Rules 13a-14 and 15d-14
                             as Adopted Pursuant to
                  Section 302 of the Sarbanes-Oxley Act of 2002


I, Charles C. Best certify that:

         1. I have  reviewed  this  quarterly  report on Form 10-Q for the three
months ended September 30, 2002;

         2. Based on my knowledge,  this  quarterly  report does not contain any
untrue  statement of a material fact or omit to state a material fact  necessary
to make the  statements  made,  in light of the  circumstances  under which such
statements  were made, not misleading with respect to the period covered by this
quarterly report;

         3. Based on my knowledge, the financial statements, and other financial
information  included in this quarterly  report,  fairly present in all material
respects the financial  condition,  results of operations  and cash flows of the
registrant as of, and for, the periods presented in this quarterly report;

         4. The registrant's other certifying officers and I are responsible for
establishing and maintaining  disclosure  controls and procedures (as defined in
Exchange Act Rules 13a-14 and 15d-14) for the registrant and we have:

                  a) designed such disclosure  controls and procedures to ensure
that material information relating to the registrant, including its consolidated
subsidiaries, is made known to us by others within those entities,  particularly
during the period in which this quarterly report is being prepared;

                  b) evaluated the effectiveness of the registrant's  disclosure
controls and  procedures as of a date within 90 days prior to the filing date of
this quarterly report (the "Evaluation Date"); and

                  c) presented in this quarterly  report our  conclusions  about
the  effectiveness  of the  disclosure  controls  and  procedures  based  on our
evaluation as of the Evaluation Date;

         5. The  registrant's  other  certifying  officers and I have disclosed,
based on our most recent evaluation,  to the registrant's auditors and the audit
committee  of  registrant's  board  of  directors  (or  persons  performing  the
equivalent function):

                  a) all significant  deficiencies in the design or operation of
internal  controls  which could  adversely  affect the  registrant's  ability to
record, process, summarize and report financial data and have identified for the
registrant's auditors any material weaknesses in internal controls; and

                  b)  any  fraud,   whether  or  not  material,   that  involves
management or other  employees who have a significant  role in the  registrant's
internal controls; and

         6. The registrant's  other certifying  officers and I have indicated in
this quarterly report whether or not there were significant  changes in internal
controls or in other factors that could  significantly  affect internal controls
subsequent to the date of our most recent  evaluation,  including any corrective
actions with regard to significant deficiencies and material weaknesses.

Date: November 11, 2002
                                                     /s/ CHARLES C. BEST
                                                     ---------------------------
                                                     Charles C. Best
                                                     Chief Financial Officer


                                       30





                                  EXHIBIT INDEX

Exhibit           Description

99.1              Certificate of our Chief Executive Officer and Chief Financial
                  Officer pursuant to Section 906 of the  Sarbanes-Oxley  Act of
                  2002.


                                       31