UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


       Date of Report (Date of Earliest Event Reported): October 27, 2004


                            IRIS INTERNATIONAL, INC.
             (Exact name of registrant as specified in its charter)


         DELAWARE                       1-11181                  94-2579751
(State or other jurisdiction     (Commission File Number)     (I.R.S. Employer
   of incorporation)                                         Identification No.)


                                9172 ETON AVENUE
                              CHATSWORTH, CA 91311
                (Address of Principal Executive Offices/Zip Code)


                                 (818) 709-1244
              (Registrant's telephone number, including area code)


         Check the  appropriate  box below if the Form 8-K filing is intended to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (SEE General Instruction A.2. below):

|_|  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

|_|  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

|_|  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange ct (17 CFR 240.14d-2(B))

|_|  Pre-commencement  communications  pursuant  to  Rule  13e-4(c))  under  the
     Exchange Act (17 CFR 240.13e-4c))





ITEM 7.01 - REGULATION FD DISCLOSURE

         On October 27, 2004,  IRIS  International,  Inc. issued a press release
updating its outlook for fiscal 2004 results of operations.  A copy of the press
release is attached  hereto as Exhibit 99.1 and is  incorporated  herein by this
reference.

         The  information in this report is furnished  pursuant to Item 7.01 and
shall not be deemed to be "filed" for  purposes of Section 18 of the  Securities
Exchange Act of 1934,  nor shall it be deemed  incorporated  by reference in any
filing under the Securities Act of 1933 or the Securities  Exchange Act of 1934,
except as shall be expressly set forth by specific reference in such a filing.



ITEM 9.01 - FINANCIAL  STATEMENTS  AND EXHIBITS  (Information  furnished in this
            Item 9.01 is furnished pursuant to Item 7.01)

         (a)      Financial Statements of business acquired.

                  Not applicable.

         (b)      Pro Forma Financial Information.

                  Not applicable.

         (c)      Exhibits.

                  The following exhibits are filed herewith:

                  Exhibit
                  Number   Description
                  -------  -----------

                  99.1     Press Release  dated  October 27, 2004,  published by
                           IRIS International, Inc.


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                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                               IRIS INTERNATIONAL, INC.



Date:    October 27, 2004             By:      /s/ Martin G. Paravato
                                               ---------------------------------
                                               Martin G. Paravato
                                               Chief Financial Officer


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                                  EXHIBIT INDEX

Exhibit
Number         Description
- -------        -----------

99.1           Press  Release   dated  October  27,  2004,   published  by  IRIS
               International, Inc.


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