UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 IRIS INTERNATIONAL, INC. (Exact Name of Registrant as Specified in Its Charter) DELAWARE 95-2579751 (State or Other Jurisdiction of (I.R.S. Employer Incorporation or Organization) Identification No.) 9172 ETON AVENUE CHATSWORTH, CALIFORNIA 91311 Address of Principal Executive Offices) (Zip Code) 1998 STOCK OPTION PLAN, AS AMENDED (Full Title of the Plans) MARTIN G. PARAVATO CHIEF FINANCIAL OFFICER IRIS INTERNATIONAL, INC. 9172 ETON AVENUE CHATSWORTH, CALIFORNIA 91311 (Name and Address of Agent for Service) (818) 709-1244 (Telephone Number, Including Area Code, of Agent for Service) Copies to: JOHN MCILVERY, ESQ. STUBBS ALDERTON & MARKILES, LLP 15821 VENTURA BOULEVARD, SUITE 525 ENCINO, CA 91436 CALCULATION OF REGISTRATION FEE ================================================================================ Proposed Proposed Maximum Maximum Title of Each Class Offering Aggregate Amount of of Securities Amount To Be Price Per Offering Registration To Be Registered Registered (1) Share (2) Price (2) Fee - -------------------------------------------------------------------------------- Common Stock, par value $.0001 per share ........... 1,200,000 $15.715 $18,858,000 $2,219.59 ================================================================================ (1) Pursuant to Rule 416(a) under the Securities Act of 1933, this Registration Statement also covers such additional shares of the Common Stock as may become issuable pursuant to the anti-dilution provisions of the 1998 Stock Option Plan, as amended. (2) Estimated solely for purposes of calculating the registration fee pursuant to Rule 457(h)(1) under the Securities Act of 1933, as amended, and based upon the average of the high and low prices of the Common Stock as quoted on the NASDAQ Stock Market on August 23, 2005. PURSUANT TO GENERAL INSTRUCTION E OF FORM S-8 ("REGISTRATION OF ADDITIONAL SECURITIES"), THE REGISTRANT HEREBY MAKES THE FOLLOWING STATEMENT: On October 9, 1998, IRIS International, Inc. (the "Company") filed with the Securities and Exchange Commission a Registration Statement on Form S-8 (Registration No. 333-65547), on September 7, 2000, the Company filed with the Securities and Exchange Commission a Registration Statement on Form S-8 (Registration No. 333-45348), on June 19, 2001, the Company filed with the Securities and Exchange Commission a Registration Statement on Form S-8 (Registration No. 333-63304), and on February 3, 2005, the Company filed with the Securities and Exchange Commission a Registration Statement on Form S-8 (Registration No. 333-122501) (collectively, the "Prior Registration Statements") relating to shares of the Common Stock to be issued pursuant to the Company's 1998 Stock Option Plan, as amended (the "Plan"), and the Prior Registration Statements are currently effective. This Registration Statement relates to securities (a) of the same class as those to which the Prior Registration Statements relate and (b) to be issued pursuant to the Plan. The contents of the Prior Registration Statements are incorporated herein by reference. THE FOLLOWING EXHIBITS ARE FILED AS PART OF THIS REGISTRATION STATEMENT: 5.1 Opinion of Stubbs Alderton & Markiles, LLP. 23.1 Consent of BDO Seidman, LLP. 23.2 Consent of Stubbs Alderton & Markiles, LLP (included in Exhibit 5.1). 24.1 Power of Attorney (included as part of the Signature Page of this Registration Statement). 2 SIGNATURES Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Chatsworth, State of California, on this 26th day of August, 2005. IRIS INTERNATIONAL, INC. (Registrant) By: /s/ Cesar M. Garcia ------------------------------------------- Cesar M. Garcia, Chief Executive Officer By: /s/ Martin G. Paravato ------------------------------------------- Martin G. Paravato, Chief Financial Officer POWER OF ATTORNEY Each person whose signature appears below constitutes and appoints Cesar M. Garcia and Martin G. Paravato, and each of them, as his true and lawful attorneys-in-fact and agents with full power of substitution and resubstitution, for him and his name, place and stead, in any and all capacities, to sign any or all amendments (including post-effective amendments) to this Registration Statement and to file a new Registration Statement under Rule 461 or Instruction E of Form S-8 of the Securities Act of 1933, as amended, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the foregoing, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or either of them, or their substitutes, may lawfully do or cause to be done by virtue hereof. Pursuant to the requirements of the Securities Act of 1933, as amended, this registration statement has been signed below by the following persons in the capacities and on the date indicated. SIGNATURE TITLE DATE --------- ----- ---- /s/ Cesar M. Garcia President and Chief Executive August 26, 2005 - ------------------------ Officer (Principal Executive Cesar M. Garcia Officer) /s/ Martin G. Paravato Chief Financial Officer and August 26, 2005 - ------------------------ Secretary (Principal Financial Martin G. Paravato Officer and Principal Accounting Officer) /s/ Richard H. Williams Chairman of the Board August 26, 2005 - ------------------------ Richard H. Williams /s/ Steven M. Besbeck Director August 26, 2005 - ------------------------ Steven M. Besbeck /s/ Thomas A. Adams Director August 26, 2005 - ------------------------ Thomas A. Adams /s/ Michael D. Matte Director August 26, 2005 - ------------------------ Michael D. Matte /s/ Richard G. Nadeau Director August 26, 2005 - ------------------------ Richard G. Nadeau 3 EXHIBIT INDEX EXHIBIT NO. EXHIBIT DESCRIPTION - ----------- ------------------- 5.1 Opinion of Stubbs Alderton & Markiles, LLP. 23.1 Consent of BDO Seidman, LLP. 23.2 Consent of Stubbs Alderton & Markiles, LLP (included in Exhibit 5.1). 24.1 Power of Attorney (included as part of the Signature Page of this Registration Statement). 4