UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


       Date of Report (Date of Earliest Event Reported): November 2, 2005


                            IRIS INTERNATIONAL, INC.
             (Exact name of registrant as specified in its charter)


          DELAWARE                       1-11181                94-2579751
(State or other jurisdiction     (Commission File Number)    (I.R.S. Employer
     of incorporation)                                       Identification No.)


                                9172 ETON AVENUE
                              CHATSWORTH, CA 91311
                (Address of Principal Executive Offices/Zip Code)


                                 (818) 709-1244
              (Registrant's telephone number, including area code)


         Check the  appropriate  box below if the Form 8-K filing is intended to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (SEE General Instruction A.2. below):

         |_|      Written   communications   pursuant  to  Rule  425  under  the
                  Securities Act (17 CFR 230.425)

         |_|      Soliciting material pursuant to Rule 14a-12 under the Exchange
                  Act (17 CFR 240.14a-12)

         |_|      Pre-commencement  communications  pursuant  to  Rule  14d-2(b)
                  under the Exchange ct (17 CFR 240.14d-2(b))

         |_|      Pre-commencement  communications  pursuant  to Rule  13e-4(c))
                  under the Exchange Act (17 CFR 240.13e-4c))





ITEM 2.02 - RESULTS OF OPERATIONS AND FINANCIAL CONDITION

            On  November  2,  2005,  we issued a press  release  announcing  our
financial results for the three and nine-month periods ended September 30, 2005.
A copy  of  the  press  release  is  attached  hereto  as  Exhibit  99.1  and is
incorporated herein by reference.

            We will host a  conference  call on November 2, 2005,  at 11:00 a.m.
EST to review our financial  results for the three and nine-month  periods ended
September  30,  2005.  The call may be accessed via a live audio web cast on our
web site at www.proiris.com or at www.vcall.com,  or through a dial-in telephone
number at 1-800-289-0572. International callers should dial 913-981-5543.

            The  information in Item 2.02 of this Current Report on Form 8-K and
Exhibit 99.1 attached  hereto shall not be deemed to be "filed" for the purposes
of Section 18 of the Securities  Exchange Act of 1934 (the "Exchange  Act"),  or
otherwise subject to the liabilities of such section, nor shall such information
or  exhibit  be  deemed  incorporated  by  reference  in any  filing  under  the
Securities  Act of 1933 or the Exchange  Act,  except as shall be expressly  set
forth by specific reference in such a filing.

ITEM 9.01 - FINANCIAL STATEMENTS AND EXHIBITS

         (c)      Exhibits.

                  The following exhibits are filed herewith:

                  EXHIBIT
                  NUMBER   DESCRIPTION
                  -------  -----------

                  99.1     Press  Release dated  November 2, 2005,  published by
                           IRIS International, Inc.


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                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                                 IRIS INTERNATIONAL, INC.



Date:    November 2, 2005                   By:  /s/ Martin G. Paravato
                                                 -------------------------------
                                                     Martin G. Paravato
                                                     Chief Financial Officer


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                                  EXHIBIT INDEX

EXHIBIT
NUMBER            DESCRIPTION
- -------           -----------

99.1              Press  Release  dated  November  2,  2005,  published  by IRIS
                  International, Inc.


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