UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


         Date of Report (Date of Earliest Event Reported): March 7, 2007


                            IRIS INTERNATIONAL, INC.
             (Exact name of registrant as specified in its charter)


          DELAWARE                    1-11181                    94-2579751
(State or other jurisdiction       (Commission                (I.R.S. Employer
      of incorporation)            File Number)              Identification No.)


                                9172 ETON AVENUE
                              CHATSWORTH, CA 91311
                (Address of Principal Executive Offices/Zip Code)


                                 (818) 709-1244
              (Registrant's telephone number, including area code)


         Check the  appropriate  box below if the Form 8-K filing is intended to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (SEE General Instruction A.2. below):

[_]      Written  communications  pursuant to Rule 425 under the  Securities Act
         (17 CFR 230.425)

[_]      Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17
         CFR 240.14a-12)

[_]      Pre-commencement  communications  pursuant to Rule  14d-2(b)  under the
         Exchange ct (17 CFR 240.14d-2(B))

[_]      Pre-commencement  communications  pursuant to Rule 13e-4(c))  under the
         Exchange Act (17 CFR 240.13e-4c))





ITEM 2.02 - RESULTS OF OPERATION AND FINANCIAL CONDITION.

ITEM 7.01 - REGULATION FD DISCLOSURE.

         On March 7,  2007,  IRIS  International,  Inc.  issued a press  release
announcing  its  financial  results  for the three  months and fiscal year ended
December 31, 2006 and outlook for fiscal year 2007 results.  A copy of the press
release  is  attached  hereto  as  Exhibit  99.1 and is  incorporated  herein by
reference.

         The  information  in this  Current  Report on Form 8-K and Exhibit 99.1
attached hereto shall not be deemed to be "filed" for the purposes of Section 18
of the  Securities  Exchange  Act of 1934 (the  "Exchange  Act"),  or  otherwise
subject  to the  liabilities  of such  section,  nor shall such  information  or
exhibit be deemed  incorporated  by reference in any filing under the Securities
Act of 1933 or the  Exchange  Act,  except  as shall be  expressly  set forth by
specific reference in such a filing.

ITEM 9.01 - FINANCIAL STATEMENTS AND EXHIBITS.

         (c)      Exhibits.

                  The following exhibits are filed herewith:

                  Exhibit
                  Number   Description
                  -------  -----------------------------------------------------
                  99.1     Press Release dated March 7, 2007,  published by IRIS
                           International, Inc.*


                  *   This exhibit is furnished, not filed.


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                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                       IRIS INTERNATIONAL, INC.

Date:    March 7, 2007                 By: /S/ CESAR M. GARCIA
                                           -------------------------------------
                                           Cesar M. Garcia
                                           President and Chief Executive Officer


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