UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


       Date of Report (Date of Earliest Event Reported): November 7, 2007


                            IRIS INTERNATIONAL, INC.
             (Exact name of registrant as specified in its charter)


         DELAWARE                     1-11181                    94-2579751
(State or other jurisdiction       (Commission               (I.R.S. Employer
      of incorporation)            File Number)             Identification No.)


                                9172 ETON AVENUE
                              CHATSWORTH, CA 91311
                (Address of Principal Executive Offices/Zip Code)


                                 (818) 709-1244
              (Registrant's telephone number, including area code)


         Check the  appropriate  box below if the Form 8-K filing is intended to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (SEE General Instruction A.2. below):

         |_|      Written   communications   pursuant  to  Rule  425  under  the
                  Securities Act (17 CFR 230.425)

         |_|      Soliciting material pursuant to Rule 14a-12 under the Exchange
                  Act (17 CFR 240.14a-12)

         |_|      Pre-commencement  communications  pursuant  to  Rule  14d-2(b)
                  under the Exchange Act (17 CFR 240.14d-2(b))

         |_|      Pre-commencement  communications  pursuant  to Rule  13e-4(c))
                  under the Exchange Act (17 CFR 240.13e-4c))





ITEM 5.02         DEPARTURE  OF  DIRECTORS  OR  CERTAIN  OFFICERS;  ELECTION  OF
                  DIRECTORS;   APPOINTMENT  OF  CERTAIN  OFFICERS;  COMPENSATORY
                  ARRANGEMENTS OF CERTAIN OFFICERS.

     AMENDMENT TO EMPLOYMENT AGREEMENT WITH CESAR M. GARCIA

         On November 14, 2007, IRIS International,  Inc. (the "Company") and Mr.
Cesar M. Garcia,  Chief Executive  Officer of the Company,  amended Mr. Garcia's
employment  agreement (the "Garcia  Amendment").  The Garcia  Amendment  revised
Section 3.7 of Mr. Garcia's employment agreement governing the timing of receipt
by Mr.  Garcia of  payments  upon his  termination  without  cause,  or for good
reason,  to avoid  adverse tax  consequences  under Section 409A of the Internal
Revenue Code of 1986, as amended ("IRC"). The Garcia Amendment also added a form
of release to be delivered by Mr. Garcia upon such termination as a condition to
receiving  severance.  All other provisions of Mr. Garcia's employment agreement
were unchanged.  A copy of the Garcia Amendment is filed as Exhibit 10.1 to this
Current Report on Form 8-K, and is incorporated herein by this reference.

     EMPLOYMENT AGREEMENT WITH ROBERT MELLO

         Effective  November 7, 2007, IRIS  International,  Inc. entered into an
employment  agreement with Robert Mello,  Corporate Vice President and President
of Statspin  Inc.  (dba IRIS Sample  Processing),  a subsidiary  of the Company.
Under  the terms of the  employment  agreement,  we can  terminate  Mr.  Mello's
employment at any time with or without cause, upon written notice. Mr. Mello has
been  employed  by the  Company  since  April  2000 and has been  serving in his
current role since  joining the Company.  Under the  employment  agreement,  Mr.
Mello will receive the following compensation:

         o        Base  salary  of  $225,000   per  annum,   subject  to  upward
                  adjustment.

         o        Based on  performance,  Mr.  Mello will be eligible for option
                  and/or  equity  awards as  determined  by the Chief  Executive
                  Officer and Compensation Committee of our Board of Directors.

         The employment  agreement also contains certain payment provisions upon
a termination  without cause by the Company. A copy of the Employment  Agreement
is filed as Exhibit 10.2 to this Current Report on Form 8-K, and is incorporated
herein by this reference.

     EMPLOYMENT AGREEMENT WITH JOHN YI

         Effective  November 7, 2007, IRIS  International,  Inc. entered into an
employment agreement with John Yi, Corporate Vice President of Operations of the
Company. Under the terms of the employment agreement,  we can terminate Mr. Yi's
employment at any time with or without cause,  upon written  notice.  Mr. Yi has
been  employed by the Company since  September  2003 and has been serving in his
current role since joining the Company.  Under the employment agreement,  Mr. Yi
will receive the following compensation:

         o        Base  salary  of  $210,000   per  annum,   subject  to  upward
                  adjustment.

         o        Based on  performance,  Mr.  Yi will be  eligible  for  option
                  and/or  equity  awards as  determined  by the Chief  Executive
                  Officer and Compensation Committee of our Board of Directors.

         The employment  agreement also contains certain payment provisions upon
a termination  without cause by the Company. A copy of the Employment  Agreement
is filed as Exhibit 10.3 to this Current Report on Form 8-K, and is incorporated
herein by this reference.


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ITEM 9.01 - FINANCIAL STATEMENTS AND EXHIBITS.

         (c)      Exhibits.

                  The following exhibits are filed herewith:

                  EXHIBIT
                  NUMBER   DESCRIPTION
                  -------  -----------

                  10.1     Second Amendment To Key Employee  Agreement for Cesar
                           M. Garcia, effective November 14, 2007,  between IRIS
                           International, Inc. and Cesar M. Garcia.

                  10.2     Key Employee  Agreement for Robert  Mello,  effective
                           November 7, 2007,  between IRIS  International,  Inc.
                           and Robert Mello.

                  10.3     Key  Employee   Agreement  for  John  Yi,   effective
                           November 7, 2007,  between IRIS  International,  Inc.
                           and John Yi.


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                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                       IRIS INTERNATIONAL, INC.



Date:    November 14, 2007             By:        /S/ CESAR M. GARCIA
                                                -----------------------------
                                                      Cesar M. Garcia
                                                      Chief Executive Officer


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