MORGAN, LEWIS & BOCKIUS LLP
                              ONE FEDERAL STREET
                          BOSTON, MASSACHUSETTS 02110

                                                     January 25, 2017

VIA EDGAR
Securities and Exchange Commission
Division of Investment Management
100 F Street, NE
Washington, D.C. 20549

    Re:  Pioneer Series Trust X (File Nos. 333-89354; 811-21108)
         Registration Statement on Form N-1A

Ladies and Gentlemen:

   This letter is to respond to comments we received from Mr. Jay Williamson of
the Staff of the Division of Investment Management of the Securities and
Exchange Commission (the "Commission") regarding Post-Effective Amendment
No. 41 to the Registration Statement on Form N-1A of Pioneer Series Trust X
(the "Registrant"), with respect to Class T shares of Pioneer Fundamental
Growth Fund (the "Fund"). Following are the Staff's comments and the
Registrant's responses thereto:


1.  Comment:   The Staff requested that the line item "Net Expenses" in the
               Fee Table be revised to read "Total Annual Fund Operating
               Expenses After Fee Waiver and Expense Reimbursement."

    Response:  The Registrant will revise the line item "Net Expenses" in the
               Fee Table to read "Total Annual Fund Operating Expenses After
               Fee Waiver and Expense Reimbursement."

2.  Comment:   The Staff noted that, based on publicly available information,
               the Fund appears to have significant allocations to the
               information technology and consumer discretionary sectors. The
               Staff requested that the Registrant add appropriate sector risk
               disclosures if these sector exposures are expected to persist
               over time.

    Response:  The Registrant notes that the disclosure in the "More on the
               Risks of Investing in the Fund," section of the Prospectus
               includes disclosure regarding the information technology and
               consumer discretionary sectors. The Registrant will revise the
               "Market Segment Risk" disclosure in the "Principal Risks"
               section of the Prospectus to address exposure to the
               information technology and consumer discretionary sectors. As
               revised, the disclosure in the "Principal Risks" section of the
               Prospectus will state:

               MARKET SEGMENT RISK. To the extent the fund emphasizes, from
               time to time, investments in a market segment, the fund will be
               subject to a greater degree to the risks particular to that
               segment, and may experience greater market fluctuation, than a
               fund without the same focus.



               Industries in the technology segment, such as information
               technology, communications equipment, computer hardware and
               software, and office and scientific equipment, are generally
               subject to risks of rapidly evolving technology, short product
               lives, rates of corporate expenditures, falling prices and
               profits, competition from new market entrants, and general
               economic conditions.

               Industries in the consumer discretionary segment, such as
               consumer durables, hotels, restaurants, media, retailing and
               automobiles, may be significantly affected by the performance
               of the overall economy, interest rates, competition, consumer
               confidence and spending, and changes in demographics and
               consumer tastes.

3.  Comment:   The Staff noted that the Registrant includes extensive
               disclosure regarding the risks of investing in real estate
               securities and REITs in the "More on the Risks of Investing in
               the Fund" section of the Prospectus, however, the principal
               investment strategy disclosure does not address these types of
               investments to the same extent. The Staff requested that the
               Registrant consider re-locating the risk disclosure included in
               the "More on the Risks of Investing in the Fund" section of the
               Prospectus or revising the principal investment strategy
               disclosure to address the Fund's investment in real estate
               securities and REITs.

    Response:  The Registrant will re-locate the disclosure regarding the
               risks of investing in real estate securities and REITs in the
               "More on the Risks of Investing in the Fund" section of the
               Prospectus to the Statement of Additional Information.

4.  Comment:   The Staff requested that the Registrant update the disclosure
               under "Investment Adviser" relating to UniCredit S.p.A. as
               necessary.

    Response:  The Registrant will update the disclosure referenced by the
               Staff to reflect that UniCredit S.p.A. has announced that it
               has entered into a binding agreement for the sale of its
               Pioneer Investments business, which includes the Fund's
               investment adviser, to Amundi S.A.

5.  Comment:   The Staff requested that the Registrant confirm whether there
               will be any scheduled variations in or eliminations of sales
               loads for Class T shares and, if so, provide appropriate
               disclosure regarding such scheduled variations in or
               eliminations of sales loads. The Staff referred the Registrant
               to the 2016 IM Guidance Update regarding mutual fund fee
               structures.

    Response:  The Registrant confirms that the scheduled variations in sales
               loads for Class T shares are set forth on pages 38-39 of the
               Prospectus.

6.  Comment:   The Staff asked if there are any limitations on eligibility for
               Class T shares and, if so, to revise the "Share
               Class Eligibility" section accordingly.

    Response:  The Registrant will add disclosure under "Share
               Class Eligibility" to clarify that Class T shares are available
               only through a financial intermediary.

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   Please call the undersigned at (617) 951-8458 or Toby Serkin at (617)
951-8760 with any questions.

                                                  Sincerely,

						  /s/ Jeremy Kantrowitz
                                                  --------------------
                                                  Jeremy Kantrowitz


cc:  Terrence J. Cullen
     Christopher J. Kelley
     Roger P. Joseph
     Toby R. Serkin

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