LIMITED POWER OF ATTORNEY

      The  undersigned  hereby  constitutes and appoints Robert Farrell, William
DeVaul  and Praveen Tipirneni, as long as they are providing services to Morphic
Holding,  Inc.,  a  Delaware  corporation  (the  "Company"), or any of them, the
undersigned's true and lawful attorney-in-fact to:

      (1)   execute  for  and on behalf of the undersigned, in the undersigned's
            capacity  as  an  officer and/or director of the Company, Forms 3, 4
            and  5  in  accordance with Section 16(a) of the Securities Exchange
            Act  of  1934,  as  amended  (the "Exchange Act"), and the rules and
            regulations thereunder;

      (2)   do and perform any and all acts for and on behalf of the undersigned
            that  may be necessary or desirable to complete and execute any such
            Forms  3,  4s  and 5s and timely file such forms with the Securities
            and Exchange Commission and any stock exchange or similar authority,
            if required; and

      (3)   take  any other action of any type whatsoever in connection with the
            foregoing  that,  in the opinion of such attorney-in-fact, may be of
            benefit  to,  in  the  best interest of, or legally required by, the
            undersigned, it being understood that the documents executed by such
            attorney-in-fact on behalf of the undersigned pursuant to this Power
            of  Attorney  shall be in such form and shall contain such terms and
            conditions   as   such   attorney-in-fact   may   approve   in  such
            attorney-in-fact's discretion.

      The undersigned hereby grants to each such attorney-in-fact full power and
authority  to  do and perform each and every act and thing whatsoever requisite,
necessary  or  proper to be done in the exercise of any of the rights and powers
herein granted, as fully to all intents and purposes as the undersigned might or
could  do if personally present, with full power of substitution and revocation,
hereby  ratifying  and  confirming  all that each such attorney-in-fact, or each
such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to
be  done  by  virtue  of this power of attorney and the rights and powers herein
granted.   The   undersigned   acknowledges   that   each   of   the   foregoing
attorneys-in-fact,   in   serving  in  such  capacity  at  the  request  of  the
undersigned,  is  not  assuming,  nor  is  the  Company  assuming,  any  of  the
undersigned's responsibilities to comply with Section 16 of the Exchange Act.

      The  undersigned  agrees that each such attorney-in-fact may rely entirely
on  information  furnished  orally or in writing by the undersigned to each such
attorney-in-fact. The undersigned also agrees to indemnify and hold harmless the
Company  and  each  such attorney-in-fact against any losses, claims, damages or
liabilities (or actions in these respects) that arise out of or are based on any
untrue  statement  or omission of necessary facts in the information provided by
the   undersigned   to   such   attorney-in-fact   for  purposes  of  executing,
acknowledging,  delivering  and  filing  Forms  3,  4 or 5 (including amendments
thereto)  and agrees to reimburse the Company and each such attorney-in-fact for
any legal or other expenses reasonably incurred in connection with investigating
or defending against any such loss, claim, damage, liability or action.

      This  Power  of  Attorney  shall remain in full force and effect until the
undersigned  is  no longer required to file Forms 3, 4 and 5 with respect to the
undersigned's  holdings of and transactions in securities issued by the Company,
unless  earlier  revoked by the undersigned in a signed writing delivered to the
foregoing attorneys-in-fact.

      IN  WITNESS  WHEREOF, the undersigned has caused this Power of Attorney to
be executed as of this 21st day of June 2019.

                                                /s/ Amir Nashat
                                                --------------------------------
                                                Name:  Amir Nashat