EXHIBIT 23.1 CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM The Board of Directors IR Biosciences Holdings, Inc.: As registered independent certified public accountants, we hereby consent to the incorporation by reference in this Registration Statement on Form S-8; of our report, which includes an explanatory paragraph regarding the substantial doubt about the Company's ability to continue as a going concern, dated March 24, 2006 included IR Biosciences Holdings, Inc.'s Annual Report on Form 10-KSB for the year ended December 31, 2005, and to all references to our firm included in this Registration Statement. /s/RUSSELL BEDFORD STEFANOU MIRCHANDANI LLP - ------------------------------------------- Russell Bedford Stefanou Mirchandani LLP New York, New York September 7, 2006