Exhibit 99.1 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT ("Agreement") is made as of January 1, 2006, at San Diego, California among LPATH, INC., a Nevada corporation (the "Company"), and SCOTT R. PANCOAST ("Employee") with reference to the following facts: In consideration of their respective promises contained herein, the parties hereto agree as follows: 1. EMPLOYMENT Employee and the Company now desire to memorialize the terms and conditions associated with the Employee's hiring as Chief Executive Officer and President, which terms and conditions shall be contained in this Agreement. 2. EMPLOYEE'S DUTIES Employee shall, while contributing his services hereunder: (a) Serve the Company in the capacity set forth in Section 1, or in such other similar chief executive capacity as the Company's Board of Directors (hereinafter, referred to as "the Board") may direct, on a full-time basis and exclusive to the Company [excluding the agreed-upon duties relating to Western States Investment Corporation ("WSIC")], using his best efforts, skills, and diligence in the performance of such duties, at such place or places as may be required for valid business reasons and as determined in the reasonable determination of the Board; (b) Report to the Board and perform the duties and exercise the powers assigned or vested in him by the Board; (c) Comply with and conform to any lawful instructions or directions given or made by the Board, and faithfully, industriously, diligently, and to the best of Employee's ability, experience, and talents, serve the Company and perform all of the duties that may be required by the terms and conditions of this Agreement to the reasonable satisfaction of the Board, so as to promote the Company's business interests; and (d) Devote himself diligently to the business interests of the Company and personally attend thereto at all times during usual business hours and during such other times as the Board may reasonably require, except in case of incapacity through illness or accident, in which case he shall furnish to the Board such evidence thereof as it may reasonably require; however, Company understands, and finds acceptable, that (i) Employee still serves on the Board of Directors of various WSIC portfolio companies ("Portfolio Boards") and/or monitors such portfolio companies' performance and still serves on the board of publicly-traded 1 iVOW, Inc. (ii) that Employee will not join any other Boards unless granted permission by Company's Board of Directors, (iii) upon a change of control with respect to any of the Portfolio Boards, Employee will resign, unless granted permission otherwise by the Company's Board of Directors, and (iv) WSIC has agreed to reimburse the Company for the time and effort Employee expends serving on the Portfolio Boards. 3. COMPENSATION In consideration of the performance by Employee of his duties hereunder, the remuneration of Employee shall be (and the Company shall pay to Employee): (a) A base salary ("Salary") of $330,000 per annum payable in accordance with the Company's normal payroll procedure, subject to normal payroll deductions. (b) Paid vacation, which shall accrue at the rate of four weeks per year. (c) Other benefits and perquisites normally available to executives of the Company, as may be changed from time to time. (d) Such additional remuneration as Employee and the Company shall negotiate after January 1, 2006. In addition, the Company shall, at least on an annual basis, review Employee's stock-option/stock-grant holdings and make reasonable efforts to keep the level of such holdings competitive with companies that are similar to the Company or, in the alternative, provide to Employee its good-faith business reasons for not doing so. 4. EXPENSES The Company shall pay on behalf of Employee or reimburse Employee (against Employee's submission to the Company of proper receipts therefore) for all expenses properly incurred by him in the course of his employment hereunder or otherwise in connection with the business of the Company in accordance with Company policies, as such policies may be established and revised by the Board from time to time. 5. AT-WILL EMPLOYMENT Employee and the Company understand and expressly agree that Employee's employment with the Company is at-will, is not for a specified term, and may be terminated by the Company or by Employee at any time, with or without notice and with or without cause. While not required, as a courtesy, the parties shall attempt if possible to give thirty (30) days' notice of termination. This clause shall not be interpreted to conflict with Employee's at-will employment status. Employee and the Company further understand 2 and agree that no representation contrary to this section is valid, and that this section may not be augmented, contradicted, or modified in any way, by any representative or agent of the Company or any other person, except by a writing signed by Employee and by the Board. 6. TERMINATION 6.1 Upon termination for any reason, including voluntary resignation, Employee shall: (a) be entitled to the compensation set forth in Section 3(a) hereof, prorated to the effective date of such termination. (b) remain subject to the provisions of the Proprietary Information and Inventions Agreement, in the form attached hereto as Exhibit A, signed concurrently herewith. (c) be entitled to receive a termination payment for any accrued, unused vacation. (d) not be entitled to severance, unless as provided in Section 6.2. 6.2 If Company terminates the employment of Employee without Cause (to be defined later in this section), the Company will, in addition to the provisions of Section 6.1, and in exchange for Employee's execution of a full and complete release of all claims as described herein: (i) Pay Employee one year's base compensation if the termination occurs BEFORE there has been a Corporate Transaction (to be defined later in this section) or pay Employee 18 months' base compensation if the termination occurs AFTER there has been a Corporate Transaction. Such payments are to be made in accordance with the Company's normal payroll procedures with normal payroll deductions. (ii) Continue to provide to Employee all heath-care benefits, and other benefits that might apply, for the remainder of the month in which the termination occurs and reimburse Employee for Employee's COBRA coverage for another twelve-month period beyond that, or for an 18-month period if the termination occurs AFTER there has been a Corporate Transaction. (iii) Accelerate a certain amount of Employee's unvested stock options, as follows: (a) If the termination occurs BEFORE there has been a Corporate Transaction, Company will (i) accelerate-vest by 24 months Employee's unvested stock options, unvested stock grants, and any other such assets that vest over time, unless the termination occurs after December 31, 2006, in which case the accelerated vesting shall be 18 months, and (ii) allow 3 Employee up to 24 months to exercise such options, except to the extent that any such options expire before the end of this 24-month period or to the extent that earlier exercise is required by the Company to effect a sale or a merger. (b) If the termination occurs within 24 months AFTER there has been a Corporate Transaction, Company will (i) accelerate vest by 24 months Employee's unvested stock options, unvested stock grants, and any other such assets that vest over time and (ii) allow Employee up to 24 months to exercise such options except to the extent that any such options expire before the end of this 24-month period. . (iv) The term "Cause" is defined to mean conduct that in the good faith judgment of the Board constitutes a material breach of duty and is to include one or more of the following that results in a material adverse impact to the Company: falsification of company documents, fraud, moral turpitude, theft, embezzlement, criminal conduct, indictment on felony criminal charges, serious violations of Company policies, material breach of Employee's employment agreement, extended or repeated absence from work that in the reasonable judgment of the Board is unjustified, inability to perform duties for a period of thirty (30) or more days without reasonable excuse and notice, or insubordination (E.G., refusal to carry out the reasonable instructions of the Board). If the material breach of duty is reasonably curable, Company shall provide notice to Employee of such breach of duty and shall give Employee a 30-day cure period. Refusal to relocate to a facility more than 50 miles from the current facility is NOT considered Cause. (v) The term "Corporate Transaction" is defined to mean (a) a transaction whereby the Company is party to a merger or consolidation whereby the Company is NOT the surviving entity and whereby the transaction results in the voting securities of the Company outstanding immediately prior thereto failing to continue to represent (either by remaining outstanding or by being converted into voting securities of the surviving or another entity) at least fifty (50%) percent of the combined voting power of the voting securities of the Company or such surviving or other entity outstanding immediately after such merger or consolidation; or (b) the sale or disposition of all or substantially all of the Company's assets (or consummation of any transaction having similar effect). (vi) Employee will be eligible for no other severance compensation, benefits, or vesting other than that which is provided for in this Section 6.2 when he is terminated. A condition precedent to the Company's obligation to fulfill the severance terms in this Section 6.2 shall be Employee's execution of a full and complete release of all claims against the Company, its Board, officers, agents, and affiliates in reasonable form as provided by the Company. Nothing in this severance provision supersedes or in any way alters the at-will provisions of Section 5 above. (vii) Employee agrees that he will surrender to the Company, at its request, or at the conclusion of his employment, all accounts, notes, data, sketches, drawings and 4 reproductions, and copies thereof, any of which (a) relate in any way to the business, products, practices, or techniques of the Company, (b) contain Confidential Information, whether or not created by him, or (c) come into his possession by reason of his employment with the Company; and Employee agrees further that all of the foregoing are the property of the Company. 7. LOYAL PERFORMANCE 7.1 Employee shall not, during the period of his employment by the Company, engage in any employment or activity in any business competitive with the Company. Employee agrees to notify the Company in writing of any outside employment or business activity, including the name of the business and the general nature of employee's involvement, during the period of Employee's employment with the Company. 7.2 If, at any time during the period ending two years after Employee has ceased to be an employee of the Company (or of any subsidiary or affiliate of the Company), whether or not pursuant to this agreement, Employee: (a) directly or indirectly engages with... (b) assists or has an active interest in, whether as owner, partner, shareholder, joint venturer, corporate officer, director, employee, consultant, principal, agent, trustee or licensor, or in any other similar capacity whatsoever (provided that ownership of not more than two percent of the outstanding stock of a corporation traded on a National securities exchange or quoted on NASDAQ OTC shall not of itself be viewed as assisting or having an active interest)... or (c) enters the employment of or acts as an agent for or advisor or consultant to... ... any person, firm, partnership, association, corporation, business organization, entity, or enterprise (the Business") that is, or is about to become, directly or indirectly, engaged in any business or program that competes directly with or is substantially similar to any business or program that the Company (or any subsidiary or affiliate of the Company) was involved in (or was in the planning or development stage) during the 120-day period immediately prior to Employee's ceasing to provide services to the Company (or any subsidiary or affiliate of the Company) [such business or program shall include, but not be limited to, those that involve: (a) any composition of matter or method that is protected by (i) any Company trade secret or (ii) any Company intellectual property that is either issued, pending, or filed at the time of termination or (b) the use, research or development, for any therapeutic or diagnostic purpose, of (i) any sphingolipid, (ii) any lysophosphatidic acid, or (iii) any component of their respective pathways], then Employee shall immediately notify Company in writing of such involvement, including the name of the Business and the nature of Employee's involvement, and Employee 5 agrees to fully respond to reasonable questions by the Company regarding such involvement and to provide such further assurances reasonably requested by Company that Employee is not and will not be in breach of the Proprietary Information and Inventions Agreement attached hereto as Exhibit A. 7.3 Employee will not, at any time, without prior written consent of the Company: (a) Directly or indirectly take any action or make or cause to be made any statements which would disparage the reputation of the Company or any subsidiary or affiliate of the Company; or (b) Induce or attempt to influence any employee or consultant of the Company or any of its or their subsidiaries or affiliates to terminate his or her employment. 7.4 Nothing contained in this Section 7 is intended to supersede or alter in any way the provisions of the Proprietary Information and Inventions Agreement attached hereto as Exhibit A. 8. CONFIDENTIALITY MATTERS 8.1 It is an express condition to the employment of Employee by Company that Employee sign and deliver a Proprietary Information and Inventions Agreement in the form attached hereto as Exhibit A concurrently with the execution of this Agreement. 8.2 The covenants contained in the Proprietary Information and Inventions Agreement constitute separate covenants. If in any judicial proceeding, a court shall hold that any of the covenants set forth in the Proprietary Information and Inventions Agreement is not permitted by applicable laws, Employee and Company agree that such provision shall and is hereby reformed to the maximum time, geographic, or occupational limitations permitted by such laws. Further, in the event a court shall hold unenforceable any of the separate covenants deemed included herein, then such unenforceable covenant or covenants shall be deemed eliminated from the provisions of this Agreement for the purpose of such proceeding to the extent necessary to permit the remaining separate covenants to be enforced in such proceeding. Employee and Company further agree that the covenants in the Proprietary Information and Inventions Agreement shall each be construed as a separate agreement independent of any other provisions of this Agreement, and the existence of any claim or cause of action by Employee against the Company whether predicated on this Agreement or otherwise, shall not constitute a defense to the enforcement by the Company of any of the covenants set forth in the Proprietary Information and Inventions Agreement. 6 9. ACKNOWLEDGMENT Employee acknowledges that he has been advised by Company to consult with independent counsel of his own choice, at his expense, as to the entering into this Agreement, that he has had the opportunity to do so, and that he has taken advantage of the opportunity to the extent that he desires. Employee further acknowledges that he has read and that he understands this Agreement, is fully aware of its legal effect, and has entered into it freely based on his own judgment and such professional advice as he has seen fit to obtain. 10. ARBITRATION Employee and the Company agree that in the event of any dispute concerning, arising out of, or related in any way to this Agreement, such dispute shall be submitted to arbitration. Except as otherwise provided for herein, the disputes subject to this agreement to arbitrate include, to the fullest extent allowable by law, all potential claims between Employee and Company including, but not limited to, breach of contract, tort, discrimination, harassment, wrongful termination, compensation and benefits claims, constitutional claims and claims for the violation of any local, state or federal statute, ordinance or regulation. Arbitration proceedings may be commenced by either party by giving the other party written notice thereof and proceeding thereafter in accordance with the rules and procedures of the American Arbitration Association and California law. Any such arbitration shall take place before a single arbitrator only in San Diego, California. Any such arbitration shall be governed by and be subject to the applicable laws of the State of California and the then-prevailing rules of the American Arbitration Association (the "AAA"). If the parties are unable to agree on a single neutral arbitrator, the arbitrator shall be selected pursuant to the AAA rules. The arbitrator's award in any such arbitration shall be final and binding, and a judgment upon such award may be entered and enforced by any court of competent jurisdiction. EACH PARTY TO THIS AGREEMENT UNDERSTANDS THAT BY AGREEING TO ARBITRATE THEIR DISPUTES, THEY ARE GIVING UP THEIR RIGHT TO HAVE THEIR DISPUTES HEARD IN A COURT OF LAW AND, IF APPLICABLE, BY A JURY. Company shall bear the costs of the arbitrator, the forum, and filing fees. Each party shall bear its own respective attorney's fees and all other costs, unless otherwise required or allowed by law and awarded by the arbitrator. 11. VIOLATION OF THE PROPRIETARY INFORMATION AND INVENTIONS AGREEMENT Employee agrees and acknowledges that the violation of any of the provisions contained in the Proprietary Information and Inventions Agreement attached hereto as Exhibit A would cause irreparable injury to the Company, the remedy at law for any violation or threatened violation thereof would be inadequate, and that the Company shall be entitled to temporary and permanent injunctive or other equitable relief without the necessity of proving actual damages. Employee agrees that such relief shall be available in a court of law in San Diego, California, regardless of the arbitration provisions contained in Section 10 of this Agreement. 7 12. MISCELLANEOUS 12.1 Amendment. This Agreement may not be modified or amended without the express prior written consent of the Company and Employee. 12.2 Notices. All notices required or permitted under this Agreement shall be in writing, shall be sent either certified mail, return receipt requested, or by facsimile transmission and mailed or sent to the relevant party at its address or facsimile number set out below (or such other address or facsimile number as the addressee has given to the other parties in accordance with the terms of this Section): TO THE COMPANY: Lpath, Inc. 6335 Ferris Square, Suite A San Diego, CA 92121 Facsimile (858) 678-0900 TO THE EMPLOYEE: Scott Pancoast Any notice, demand or other communication so addressed to the relevant party shall be deemed to have been delivered (a) if given or made by certified letter, return receipt requested, when actually delivered to the relevant party; and (b) if given or made by facsimile, upon receipt of a transmission report confirming receipt. 12.3 Entire Agreement. This Agreement and the Exhibits attached hereto contain the entire agreement of the parties regarding the employment of Employee, and there are no other promises or conditions regarding Employee's employment in any other agreement, whether oral or written. This Agreement shall terminate and supersede any previous employment agreements or arrangements between Employee and Company. 12.4 Assignment. The rights and obligations of the Company under this Agreement shall inure to the benefit of and shall be binding upon the successors and assigns of the respective corporation. Employee shall not be entitled to assign any of his rights or obligations under this Agreement. 12.5 Sections. References herein to Sections are to the sections in this Agreement, unless the context requires otherwise. 12.6 Headings. The section headings are inserted for convenience only and shall not affect the construction of this Agreement. 12.7 Rules of Construction. Unless the context requires otherwise, words importing the singular include the plural and vice versa, and words importing a gender include every gender. 8 12.8 Severability. Whenever possible, each provision of this Agreement will be interpreted in such manner as to be effective and valid under applicable law, but if any provision of this Agreement is held to be invalid, illegal or unenforceable in any respect under applicable law or rule in any jurisdiction, such invalidity, illegality or unenforceability will not affect any other provision or any other jurisdiction, but this Agreement will be reformed, construed and enforced in such jurisdiction as if such invalid, illegal or unenforceable provision had never been contained therein. 12.9 Survival. Any variation in salary or conditions mutually agreed upon after the effective date of this Agreement shall not constitute a new agreement; instead, the terms and conditions of this Agreement, except as to such variation, shall continue in force. 12.10 Waiver. The failure of either party to enforce any provision of this Agreement shall not be construed as a waiver or limitation of that party's right to subsequently enforce and compel strict compliance with every provision of this Agreement. 12.11 Interpretation. This Agreement shall not be construed against any party on the grounds that such party drafted the Agreement or caused it to be drafted. 12.12 Governing Law. This Agreement shall be governed by the laws of the State of California. Any controversy or claim arising out of or relating to this Agreement or the breach thereof, whether involving remedies at law or equity, shall be adjudicated in San Diego, California. 12.13 No Conflicting Agreements. Employee represents and warrants to the Company that he is not a party to or bound by any confidentiality, noncompetition, nonsolicitation or other agreement or restriction which could conflict with or be violated by the performance of Employee's duties to the Company under this Agreement or otherwise. Employee agrees that he will not disclose to the Company, use, or induce the Company to use, any invention or confidential information belonging to any third party. 9 IN WITNESS WHEREOF, the parties hereto have executed this Agreement on the day and year first written above. THE COMPANY EMPLOYEE By: ---------------------------------- ---------------------------------- Its: Signature --------------------------------- ---------------------------------- Print Name 10