As filed with the Securities and Exchange Commission on July 9, 2007
Registration No. 333-______
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
______________________
POST-EFFECTIVE AMENDMENT NO. 1
TO
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
______________________
ACAMBIS PLC
(Exact name of registrant as specified in its charter)
England and Wales N/A
(State or other jurisdiction of Incorporation or organization) (IRS Employer Identification Number)
Peterhouse Technology Park, 100 Fulbourn Road
Cambridge, CB1 9PT, United Kingdom
(Address of principal executive offices)
_____________________________________
The Acambis 2006 Deferred Bonus Plan
The Acambis plc 2006 Unapproved Share Option Plan
The Acambis US Employee Stock Purchase Plan
1999 Share Option Plan
and
Options assumed in connection with the acquisition of Oravax, Inc.
and originally granted under the
Oravax, Inc. 1990 Stock Option Plan
and 1995 Stock Option Plan
(Full title of the Plans)
_________________________________________
Ian Garland
Chief Executive Officer
Peterhouse Technology Park, 100 Fulbourn Road
Cambridge, CB1 9PT, United Kingdom
011-44-1223-275-300
(Name, address and telephone number of agent for service)
Copy to:
Kristian E. Wiggert, Esq.
Morrison & Foerster MNP
7th Floor, CityPoint, One Ropemaker Street
London, EC2Y 9AW, United Kingdom
011-44-207-920-4000
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EXPLANATORY NOTE/DEREGISTRATION OF UNSOLD SECURITIES
This post-effective amendment relates to the following Registration Statements filed on Form S-8 (collectively, the
"Registration Statements"):
1 Registration Statement 333-140540, filed February 9, 2007, registering 1,000,000 ordinary shares s for The Acambis 2006
Deferred Bonus Plan;
2. Registration Statement 333-137759, filed October 3, 2006, registering 2,000,000 ordinary shares for The Acambis plc 2006
Unapproved Share Option Plan;
3. Registration Statement 333-109577, filed October 9, 2003, registering 1,000,000 ordinary shares for The Acambis US Employee
Stock Purchase Plan;
4. Registration Statement 333-100028, filed September 24, 2002, registering 4,835,121 ordinary shares for the 1999 Share
Option Plan; and
5. Registration Statement 333-100028, filed May 12, 1999, registering 618,797 ordinary shares for the Options assumed in
connection with the acquisition of Oravax, Inc. and originally granted under the Oravax, Inc. 1990 Stock Option Plan and
1995 Stock Option Plan.
On June 6, 2007, Acambis filed a Form 15F to terminate the registration of its ordinary shares under the Securities Exchange
Act of 1934, as amended. In accordance with an undertaking made by Acambis in each of the Registration Statements to remove from
registration by means of a post-effective amendment any securities which remain unsold at the termination of the offering, Acambis
hereby amends the Registration Statements to withdraw from registration the securities registered but unsold under the Registration
Statements.
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SIGNATURES
Pursuant to the requirements of the Securities Act, the Registrant, Acambis plc, certifies that it has reasonable
grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Post-Effective
Amendment No. 1 to Form S-8 Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized,
in the City of Cambridge, England, on July 9, 2007.
ACAMBIS PLC
By: /s/ Ian Garland_______________________________
Name: Ian Garland
Title: Chief Executive Officer
POWER OF ATTORNEY
Each person whose signature appears below constitutes and appoints Ian Garland
and Elizabeth Brown, and each of them, as attorneys-in-fact, each with the power of substitution, for him in any and all
capacities, to sign any amendments (including post-effective amendments) and supplements to this Post-Effective
Amendment No. 1 to the Registration Statement on Form S-8 and to cause the same to be filed, with exhibits thereto and other
documents in connection therewith, with the Securities and Exchange Commission, granting to said attorneys-in-fact,
full power and authority to do and perform each and every act and thing requisite and necessary to be done in
connection therewith, as fully to all intents and purposes as he might or could do in person, hereby ratifying and
confirming the said attorney-in-fact or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this Post-Effective Amendment No. 1 to the Registration
Statement on Form S-8 has been signed by or on behalf of the following persons in the capacities indicated as of July 9, 2007:
Signature Title Date
/s/ Ian Garland Chief Executive Officer and Director July 9, 2007
Ian Garland
/s/ Elizabeth Brown Acting Chief Financial Officer, and July 9, 2007
Elizabeth Brown Secretary
Non-Executive Chairman July 6, 2007
/s/ Dr. Peter Fellner
Dr. Peter Fellner
/s/ Dr. Michael Watson Executive Vice President and Director July 9, 2007
Dr. Michael Watson
Non-Executive Director July 6, 2007
/s/ Dr. Randal Chase
Dr. Randal Chase
/s/ Alan Dalby Non-Executive Director July 6, 2007
Alan Dalby
Non-Executive Director July 9, 2007
/s/ Ross Graham
Ross Graham
Non-Executive Director July 9, 2007
/s/ Dr. William Jenkins
Dr. William Jenkins
Non-Executive Director July 9, 2007
/s/ John Lambert
John Lambert
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