Nuveen Insured Tax-Free Advantage Municipal Fund 2 333 West Wacker Drive Chicago, Illinois 60606 December 2, 2004 U.S. Securities and Exchange Commission 450 Fifth Street, N.W. Washington, D.C. 20549 Re: Nuveen Insured Tax-Free Advantage Municipal Fund 2 (CIK: 0001218077) Request for Withdrawal of Registration Statement on Form N-2 File No. 811-21303 Ladies and Gentlemen: On February 11, 2003, Nuveen Insured Tax-Free Advantage Municipal Fund 2 (the "Registrant") filed a registration statement on Form N-2 relating to the registration of common shares of beneficial interest of Nuveen Insured Tax-Free Advantage Municipal Fund 2 (accession number 000950131-03-000516). The registration statement has not yet become effective. Pursuant to Rule 477(a) under the Securities Act of 1933, the Registrant hereby requests the withdrawal of the above mentioned Form N-2 for Nuveen Insured Tax-Free Advantage Municipal Fund 2. Sincerely, Nuveen Insured Tax-Free Advantage Municipal Fund 2 (Registrant) By: /s/ Jessica R. Droeger -------------------------------------- Jessica R. Droeger Vice President and Secretary