January 15, 2010 Securities & exchange Commission 450 Fifth Street, NW Washington, DC 20549 Attn.: Document Control RE:	American Depositary Shares evidenced by the American Depositary Receipts each representing Ten (10) Ordinary Shares of XTL Biopharmaceuticals Ltd. (Form F-6 File No. 333- 147677) Ladies and Gentlemen: Pursuant to Rule 424(b)(3) under the Securities Act of 1933, as amended, on behalf of The Bank of New York, as Depositary for securities against which American Depositary Receipts are to be issued, we attach a copy of the new prospectus (Prospectus) reflecting in number of ordinary shares represented by one American Depositary Share (the Ratio). As required by Rule 424(e), the upper right hand corner of the Prospectus cover page has a reference to Rule 424(b)(3) and to the file number of the registration statement to which the Prospectus relates. Pursuant to Section III B of the General Instructions to the Form F-6 Registration Statement, the Prospectus consists of the ADR certificate with revised ratio and par value for XTL Biopharmaceuticals Ltd. The Prospectus has been revised to reflect the new par value and ratio, and has been overstampted with: Effective June 22, 2009 the Companys American Depositary Share (ADS) Ratio Changed from 1:10 (One ADS Representing Ten Ordinary Shares to 1:2 (One ADS Representing Two Ordinary Shares) and the Par Value Changed from ILS 0.02 to ILS 0.10. Please contact me with any questions or comments at 212 815-8223 Agness Moskovits Assistant Vice President The Bank of New York Mellon - ADR Division Encl. CC: Paul Dudek, Esq. (Office of International Corporate Finance) 101 Barclay Street, New York NY 10286