Exhibit 12.2

CERTIFICATION ON THE EFFECTIVENESS OF DISCLOSURE CONTROLS AND
PROCEDURES IN FORM 20-F FOR 2004

In the Form 20-F for 2004 I have certified that:

     1.   I have reviewed this annual report on Form 20-F of Novo Nordisk;

     2.   Based on my  knowledge,  this  report  does  not  contain  any  untrue
          statement  of a  material  fact  or  omit to  state  a  material  fact
          necessary to make the statements  made, in light of the  circumstances
          under which such  statements were made, not misleading with respect to
          the period covered by this report;

     3.   Based on my knowledge,  the financial statements,  and other financial
          information  included in this report,  fairly  present in all material
          respects the financial condition, results of operations and cash flows
          of the company as of, and for, the periods presented in this report;

     4.   The company's  other  certifying  officer(s) and I are responsible for
          establishing  and maintaining  disclosure  controls and procedures (as
          defined in Exchange Act Rules  13a-15(e) and  15d-15(e))  and internal
          control  over  financial  reporting  (as defined in Exchange Act Rules
          13a-15(f) and 15d-15(f) for the company and have:

               (a) Designed such disclosure  controls and procedures,  or caused
          such  disclosure  controls  and  procedures  to be designed  under our
          supervision,  to ensure  that  material  information  relating  to the
          company, including its consolidated subsidiaries,  is made known to us
          by others  within those  entities,  particularly  during the period in
          which this report is being prepared;

                  (b) Designed such internal control over financial
         reporting, or caused such internal control over financial reporting to
         be designed under our supervision, to provide reasonable assurance
         regarding the reliability of financial reporting and the preparation of
         financial statements for external purposes in accordance with generally
         accepted accounting principles;



NOVO NORDISK A/S    Novo Alle           Telephone:         Internet:
                    2880 Bagsvaerd      +45 4444 8888      www.novonordisk.com
                    Denmark                                CVR Number:
                                                           24 25 67 90



               (c)  Evaluated  the  effectiveness  of the  company's  disclosure
          controls and procedures  and presented in this report our  conclusions
          about the effectiveness of the disclosure controls and procedures,  as
          of the  end of the  period  covered  by  this  report  based  on  such
          evaluation; and

               (d) Disclosed in this report any change in the company's internal
          control  over  financial  reporting  that  occurred  during the period
          covered by the  annual  report  that has  materially  affected,  or is
          reasonably likely to materially affect, the company's internal control
          over financial reporting; and

     5.   The company's other certifying officer(s) and I have disclosed,  based
          on our most recent  evaluation  of  internal  control  over  financial
          reporting,  to the company's  auditors and the audit  committee of the
          company's  board of directors (or persons  performing  the  equivalent
          functions):

               (a) All significant  deficiencies and material  weaknesses in the
          design or operation of internal control over financial reporting which
          are reasonably likely to adversely affect the registrant's  ability to
          record, process, summarize and report financial information; and

               (b) Any fraud, whether or not material,  that involves management
          or  other  employees  who  have a  significant  role in the  company's
          internal control over financial reporting.

Date: 21 February 2005

/s/ Jesper Brandgaard
- -------------------------------------------------------
[Jesper Brandgaard]
[Chief Financial Officer]