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                                  UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

     PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

                                November 23, 2005
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                Date of Report (Date of earliest event reported)

                                PhotoMedex, Inc.
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             (Exact name of Registrant as specified in its charter)

              Delaware                 0-11635            59-2058100
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    (State or other jurisdiction     (Commission       (I.R.S. Employer
           of incorporation)         File Number)     Identification No.)

     147 Keystone Drive, Montgomeryville, Pennsylvania           18936
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          (Address of principal executive offices)             (Zip Code)

                                 (215) 619-3600
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               Registrant's telephone number, including area code

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

[ ] Written communications pursuant to Rule 425 under the Securities
    Act (17 CFR 230.425)

[ ] Soliciting material pursuant to Rule 14a-12 under the Exchange
    Act (17 CFR 240.14a-12)

[ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange
    Act (17 CFR 240.14d-2(b))

[ ] Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange
    Act (17 CFR 240.13e-4(c))

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ITEM 8.01. OTHER EVENTS.

Regulation FD Disclosure. On November 23, 2005, the Registrant announced that
Highmark Blue Cross and Blue Shield, the largest insurance company in
Pennsylvania, based on membership, and one of the largest health insurers in the
United States, had approved for reimbursement procedures using the XTRAC(R)
excimer laser to treat psoriasis.

         The information contained herein and in the accompanying exhibit shall
not be incorporated by reference into any filing of the Registrant, whether made
before or after the date hereof, regardless of any general incorporation
language in such filing, unless expressly incorporated by specific reference to
such filing. The information in this report, including the exhibit hereto, shall
not be deemed to be "filed" for purposes of Section 16 of the Securities
Exchange Act of 1934, as amended, or otherwise subject to the liabilities of
that section or Sections 11 and 12 (a) (2) of the Securities Act of 1933, as
amended.

         A copy of the press release issued by the Registrant concerning the
announcement is furnished herewith as Exhibit 99.1.

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ITEM 9.01. FINANCIAL STATEMENTS AND EXHIBITS.

(c) EXHIBITS.

         99.1    Press Release, dated November 23, 2005.

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                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

                                                     PHOTOMEDEX, INC.

Dated: November 23, 2005                             By: /s/Jeffrey F. O'Donnell
                                                         -----------------------
                                                         Jeffrey F. O'Donnell
                                                         Chief Executive Officer

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                                  EXHIBIT INDEX

         Exhibit Number               Description
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              99.1        Press release, dated November 23, 2005.

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