EXHIBIT 32.1

                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                       AS ADOPTED PURSUANT TO SECTION 906
                        OF THE SARBANES-OXLEY ACT OF 2002

     In connection with the Annual Report of Perma-Fix Environmental Services,
Inc. ("PESI") on Form 10-K for the year ended December 31, 2005 as filed with
the Securities and Exchange Commission on the date hereof (the "Form 10-K"), I
Dr. Louis F. Centofanti, Chief Executive Officer of the Company, certify,
pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002, that:

     (1) The Form 10-K fully complies with the requirements of Section 13(a) or
     15(d) of the Securities Exchange Act of 1934 (15 U.S.C. Section 78m or
     Section 78o(d)); and

     (2) The information contained in the Form 10-K fairly presents, in all
     material respects, the financial condition and results of operations of the
     Company.


Dated: March 30, 2006


/s/ Louis F. Centofanti
- --------------------------
Dr. Louis F. Centofanti
President and
Chief Executive Officer

This certification is furnished to the Securities and Exchange Commission solely
for purpose of 18 U.S.C. Section 1350 subject to the knowledge standard
contained therein, and not for any other purpose.