UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No. ) (RULE 13d-102) Information to be included in statements filed pursuant to Rule 13d-1 (b) (c) and (d) and Amendments thereto filed pursuant to Rule 13d-2 (b). Threshold Pharmaceuticals Inc (Name of Issuer) Common shares (Title of Class of Securities) 885807206 (CUSIP/SEDOL Number) December 31, 2016 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [X] 	Rule 13d-1 (b) [ ]	Rule 13d-1 (c) [ ]	Rule 13d-1 (d) 	*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. 	The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). SCHEDULE 13G Issuer: Threshold Pharmaceuticals Inc CUSIP No.: 885807206 1	NAMES OF REPORTING PERSONS I.R.S. 	IDENTIFICATION NOS. OF ABOVE PERSONS 	First Eagle Investment Management, LLC 	Tax ID # 57-1156902 2	CHECK THE APPROPRIATE BOX IF A MEMBER 	OF A GROUP 	(a) 	(b) 3	SEC USE ONLY 4	CITIZENSHIP OR PLACE OF ORGANIZATION 	State of Delaware NUMBER OF SHARES	5 SOLE VOTING POWER - 7,093,802 BENEFICIALLY 		6 SHARED VOTING POWER - 0 OWNED BY EACH	 	7 SOLE DISPOSITIVE POWER - 7,093,802 REPORTING PERSON 	8 SHARED DISPOSITIVE POWER - 0 WITH: 9	AGGREGATE AMOUNT BENEFICIALLY OWNED 	BY EACH REPORTING PERSON 	7,093,802 10	CHECK IF THE AGGREGATE AMOUNT IN 	ROW (11) EXCLUDES CERTAIN SHARES 	N/A 11	PERCENT OF CLASS REPRESENTED BY AMOUNT 	IN ROW 9: 	9.91% 12	TYPE OF REPORTING PERSON 	IA SCHEDULE 13G Issuer: Threshold Pharmaceuticals Inc CUSIP No.: 885807206 ITEM 1 (a)	Name of Issuer: Threshold Pharmaceuticals Inc (b)	Address of Issuer's Principal Executive Offices: 	170 Harbor Way, Suite 300 	South San Francisco, CA 94080 ITEM 2 (a)	Name of Person Filing: First Eagle Investment Management, LLC (b)	Address of Principal Business Office: 	1345 Avenue of the Americas 	New York, NY 10105 (c)	Citizenship: Delaware, USA (d)	Title of Class of Securities: 	Common Stock (e)	CUSIP No.: 885807206 ITEM 3 If this statement is filed pursuant to Sections 240. 13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a: (a)	[ ]	Broker or dealer registered under 		Section 15 of the Act (15 U.S.C. 78o); (b)	[ ]	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c); (c) 	[ ]	Insurance Company as defined in section 		3(a)(19) of the Act (15 U.S.C. 78C); (d)	[ ]	Investment company registered under Section 		8 of the Investment Company Act if 1940 		(15 U.S.C. 80a-8); (e)	[X]	An investment adviser in accordance with Section 		240.13d-1(b)(1)(ii)(E); (f)	[ ]	An employee benefit plan or endowment fund in accordance with 		Section 240.13d-1(b)(1)(ii)(F); (g)	[ ]	A parent holding company or control person in accordance with 		Section 240.13d-1(b)(1)(ii)(G); (h)	[ ]	A savings associations as defined in Section 3(b) of the 		Federal Deposit Insurance Act (12 U.S.C. 1813); (i)	[ ]	A church plan that is excluded from the 		definition of an insurance company under Section 3 (c)(14) of 		the Investment Company Act of 1940 (15 U.S.C. 80a-3); (j)	[ ]	Group, in accordance with section 240.13d-1 (b)(1)(ii)(J). SCHEDULE 13G Issuer: Threshold Pharmaceuticals Inc CUSIP No.: 885807206 ITEM 4.	Ownership. 	N/A ITEM 5. Ownership of Five Percent or Less of a Class. 	N/A ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON 	First Eagle Investment Management, LLC (FEIM), an investment adviser 	registered under Section 203 of the Investment Advisers Act of 1940, 	is deemed to be the beneficial owner of 7,093,802 shares, or 9.91% 	of the common stock believed to be outstanding as a result of 	acting as investment adviser to various clients. Clients of FEIM 	have the right to receive and the ultimate power to direct the 	receipt of dividends from, or the proceeds of the sale of, such 	securities. ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE 	SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY OR CONTROL 	PERSON. 	N/A ITEM 8. Identification and Classification of Members of the Group. 	N/A ITEM 9. Notice of Dissolution of Group 	N/A ITEM 10. Certification 	By signing below I certify that, to the best of my knowledge and 	belief, the securities referred to above were acquired and held in the 	ordinary course of business and were not acquired and are not held for the 	purpose of or with the effect of changing or influencing the control of the 	issuer of such securities and were not acquired and are not held in 	connection with or as a participant in any transaction having that purpose 	of effect. SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Date:		February 6, 2017 Signature:	/s/ Michael M. Kellen Name/Title:	Michael M. Kellen, /Director