U.S. Securities and Exchange Commission
                             Washington, D.C. 20549

                                    FORM S-8

                             Registration Statement
                        Under the Securities Act of 1933

                                ANGIOGENEX INC.
- -------------------------------------------------------------------------------
               (Exact Name of Registrant as specified in charter)


         Nevada                     000-26181                 86-0945116
 ------------------------    ------------------------   ----------------------
 (State of Incorporation)       (SEC File Number)       (IRS Employer I.D. No.)

                           425 MADISON AVE STE 902
                           NEW YORK, NEW YORK  10017
- -------------------------------------------------------------------------------
                    (Address of principal executive offices)

                        LEGAL/ADMINISTRATIVE OPTION PLAN
                        --------------------------------
                            (Full Title of the Plan)


                           Richard Salvador, Ph.D.
                         425 Madison Ave., Suite 902
                             New York, NY  10017
- -------------------------------------------------------------------------------
                     (Name and Address of agent for Service)


                                 (212) 874-6608
          -------------------------------------------------------------
          (Telephone number, including area code for agent for service)








                         CALCULATION OF REGISTRATION FEE

===============================================================================
                                    Proposed        Proposed
Title of          (1)               maximum         maximum
securities        Securities        offering        aggregate      Amount of
to be             to be             price per       offering       Registration
registered        registered        share (2)       price (2)      Fee (3)
- ----------        ----------        ---------       ---------      ------------
                                                       
Common $.001      200,000           $0.54           $108,000       $3.32
par value         shares
===============================================================================


(1)   This Registration Statement relates to 200,000 shares of the
      Registrant's Common Stock, par value $0.001 per share, to be issued
      pursuant to the terms of the Legal/Administrative Option Plan with
      the Law Offices of Thomas C. Cook.

(2)   Estimated pursuant to Rule 457(c) solely for purposes of calculating the
      amount of the registration fee, based upon the average of the bid and
      asked prices reported on May 25, 2007 by the NASD OTC Bulletin Board.


                                EXPLANATORY NOTE

      In accordance with the instructional Note to Part I of Form S-8 as
promulgated by the Securities and Exchange Commission, the information
specified in Part I of Form S-8 has been omitted from this Registration
Statement on Form S-8 for offers of Common Stock pursuant to the
Legal/Administrative Option Plan.





                                      PART I

              INFORMATION REQUIRED IN THE SECTION 10(A) PROSPECTUS

        The following documents listed under this Part I and the documents
incorporated by reference under Item 3 of Part II to this Form S-8, taken
together, constitute a prospectus that meets the requirements of Section 10(a)
of the Securities Act, and are incorporated herein by reference.

Item 1. PLAN INFORMATION

        The information required to be provided pursuant to this Item to the
individual participants of Law Offices of Thomas C. Cook, who include:  Thomas
C. Cook, Esq., MQ Holdings, business manager, T. J. Jesky, document preparer
and Edward C. Zimmerman III, EDGAR filing agent as set forth in the
Legal/Administrative Option Plan dated January 31, 2007.  See Exhibit 10.5.

                                     PART II

Item 3.  INCORPORATION OF DOCUMENTS BY REFERENCE

The following documents heretofore filed by the Company with the Commission
pursuant to the Exchange Act are hereby incorporated by reference, except as
superseded or modified herein:

(a)   The Company's annual report on Form 10-KSB for the fiscal year ended
      December 31, 2006.

(b)   All other reports filed pursuant to Section 13(a) or 15(d) of the
      Exchange Act since the end of the fiscal year covered by the Company's
      annual report referred to in (a) above.

      In addition, all documents subsequently filed pursuant to Sections 13(a),
13(c), 14 and 15(d) of the Securities Exchange Act of 1934, prior to the filing
of a post-effective amendment to the registration statement which indicates
that all of the shares of common stock offered have been sold or which  de-
registers all of the shares then remaining unsold, will be deemed to be
incorporated by reference in the registration statement and to be a part
hereof from the date of filing of the documents.  Any statement contained in
a document incorporated or superseded for purposes of this  registration
statement, to the extent that a statement contained  herein or in any other
subsequently filed document which also is or is deemed to be incorporated by
reference herein modifies or supersedes such statement. Any such statement so
modified or superseded will not be deemed, except as so modified or superseded,
to constitute a part of this registration statement.

Item 4.     DESCRIPTION OF SECURITIES

      Not applicable, the class of securities to be offered is registered under
Section 12 of the Securities Exchange Act of 1934.

Item 5.     INTERESTS OF NAMED EXPERTS AND COUNSEL.

      Certain legal matters in connection with this registration statement will
be passed upon for AngioGenex, Inc. by the Law Offices of Thomas C. Cook.  Mr.
Cook will become a shareholder of the registrant once the shares are issued
pursuant to this S-8 registration statement.  Some shares registered under
this plan will be paid to Mr. Cook for legal services in the future.

Item 6.     INDEMNIFICATION OF OFFICERS AND DIRECTORS.

THE ARTICLES OF INCORPORATION OF THE COMPANY PROVIDE FOR INDEMNIFICATION OF
EMPLOYEES AND OFFICERS IN CERTAIN CASES.  INSOFAR AS INDEMNIFICATION FOR
LIABILITIES ARISING UNDER THE SECURITIES ACT OF 1933 MAY BE PERMITTED TO
DIRECTORS, OFFICERS OR PERSONS CONTROLLING THE COMPANY PURSUANT TO THE
FOREGOING PROVISIONS, THE COMPANY HAS BEEN INFORMED THAT IN THE OPINION OF
THE SECURTIES AND EXCHANGE COMMISSION SUCH INDEMNIFICATION IS AGAINST PUBLIC
POLICY AS EXPRESSED IN THE ACT AND IS THEREFORE UNENFORCEABLE.

In addition, Section 78.751 of the Nevada General Corporation Laws provides
as follows: 78.751 Indemnification of officers, directors, employees and
agents; advance of expenses.

1.  A corporation may indemnify any person who was or is a party or is
threatened to be made a party to any threatened, pending or completed
action, suit or proceeding, whether civil, criminal, administrative or
investigative, except an action by or in the right of the corporation, by
reason of the fact that he is or was a director, officer, employee or agent
of the corporation, or is or was serving at the request of the corporation
as a director, officer, employee or agent of another corporation, partnership,
joint venture, trust or other enterprise, against expenses, including
attorney's fees, judgments, fines and amounts paid in settlement actually
and reasonably incurred by him in connection with the action, suitor
proceeding if he acted in good faith and in a manner which he reasonably
believed to be in or not opposed to the best interests of the corporation,
and, with respect to any criminal action or proceeding, had no reasonable
cause to believe his conduct was unlawful.  The termination of any action,
suit or proceeding by judgment, order, settlement, conviction, or upon a plea
of nolo contendere or its equivalent, does not, of itself, create a
presumption that the person did not act in good faith and in a manner which
he reasonably believed to be in or not opposed to the best interests of the
corporation, and that, with respect to any criminal action or proceeding, he
had reasonable cause to believe that his conduct was unlawful.

2.  A corporation may indemnify any person who was or is a party or is
threatened to be made a party to any threatened, pending or completed action
or suit by or in the right of the corporation to procure a judgment in its
favor by reason of the fact that he is or was a director, officer, employee
or agent of the corporation, or is or was serving at the request of the
corporation as a director, officer, employee or agent of another corporation,
partnership, joint venture, trust or other enterprise against expenses,
including amounts paid in settlement and attorneys' fees actually and
reasonably incurred by him in connection with the defense or settlement of the
action or suit if he acted in good faith and in a manner which he reasonably
believed to be in or not opposed to the best interests of the corporation.
Indemnification may not be made for any claim, issue or matter as to which
such a person has been adjudged by a court of competent jurisdiction, after
exhaustion of all appeals therefrom, to be liable to the corporation or for
amounts paid in settlement to the corporation, unless and only to the extent
that the court in which the action or suit was brought or other court of
competent jurisdiction determines upon application that in view of all the
circumstances of the case, the person is fairly and reasonably entitled to
indemnity for such expenses as the court deems proper.

3.  To the extent that a director, officer, employee or agent of a
corporation has been successful on the merits or otherwise in defense of
any action, suit or proceeding referred to in subsections 1 and 2, or in
defense of any claim, issue or matter therein, he must be indemnified by
the corporation against expenses, including attorneys' fees, actually and
reasonably incurred by him in connection with the defense.

4.  Any indemnification under subsections 1 and 2, unless ordered by a court
or advanced pursuant to subsection 5, must be made by the corporation only as
authorized in the specific case upon a determination that indemnification of
the director, officer, employee or agent is proper in the circumstances. The
determination must be made: (a) By the stockholders: (b) By the board of
directors by majority vote of a quorum consisting of directors who were not
parties to act, suit or proceeding; (c) If a majority vote of a quorum
consisting of directors who were not parties to the act, suit or proceeding
so orders, by independent legal counsel in a written opinion; or (d) If a
quorum consisting of directors who were not parties to the act, suit or
proceeding cannot to obtained, by independent legal counsel in a written
opinion; or

5.  The Articles of Incorporation, the Bylaws or an agreement made by the
corporation may provide that the expenses of officers and directors incurred
in defending a civil or criminal, suit or proceeding must be paid by the
corporation as they are incurred and in advance of the final disposition of
the action, suit or proceeding, upon receipt of an undertaking by or on
behalf of the director or officer to repay the amount if it is ultimately
determined by a court of competent jurisdiction that he is not entitled to
be indemnified by corporation. The provisions of this subsection do not
affect any rights to advancement of expenses to which corporate personnel
other than the directors or officers may be entitled under any contract or
otherwise by law.

6.  The indemnification and advancement of expenses authorized in or ordered
by a court pursuant to this section: (a) Does not exclude any other rights to
which a person seeking indemnification or advancement of expenses may be
entitled under the articles of incorporation or any bylaw, agreement, vote of
stockholders or disinterested directors or otherwise, for either an action in
his official capacity or an action in another capacity while holding his
office, except that indemnification, unless ordered by a court pursuant to
subsection 2 or for the advancement of expenses made pursuant to subsection
5, may not be made to or on behalf of any director or officer if a final
adjudication establishes that his act or omissions involved intentional
misconduct, fraud or a knowing violation of the law and was material to the
cause of action. (b) Continues for a person who has ceased to be a director,
officer, employee or agent and endures to the benefit of the heirs, executors
and administrators of such a person.  Insofar as indemnification for
liabilities arising under the Securities Act may be permitted to directors,
officers and controlling persons of the Registrant pursuant to the foregoing
provisions, or otherwise, the Registrant has been advised that in the opinion
of the Securities and Exchange Commission such indemnification is against
public policy as expressed in the Securities Act and is, therefore,
unenforceable.  In the event that a claim for indemnification against such
liabilities (other than the payment by the registrant of expenses incurred
or paid by a director, officer or controlling person of the Registrant in the
successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities
being registered, the Registrant will, unless in the opinion of its counsel
the matter has been settled by controlling precedent, submit to a court of
appropriate jurisdiction the question whether such indemnification by it is
against public policy as expressed in the Securities Act and will be governed
by the final adjudication of such issue.

Item 7.     EXEMPTION FROM REGISTRATION CLAIMED.

      Not Applicable.

Item 8.     EXHIBITS.

      The following documents are incorporated by reference from the Company's
Periodic Report filings, SEC File # 000-26181, as filed with the Securities &
Exchange Commission.

Exhibit Number    Description
- --------------    -----------

(3.1)*            Articles of Incorporation of AngioGenex, Inc.
(3.2)*            Amended Articles of AngioGenex, Inc.
(3.3)*            By-Laws
(3.4)*            Amended Articles of AngioGenex, Inc.
(5.1)             Opinion of Counsel and consent regarding the legality of the
                  securities registered under this Registration Statement
(10.5)            Legal/Administrative Option, dated January 31, 2007
(23.1)            Consent of Independent Certifying Public Accountant

- -------------------
* Previously filed.

Item 9.     UNDERTAKINGS.

      The undersigned registrant hereby undertakes:

     (1) To file, during any period in which offers and sales are being made,
a post-effective amendment to this registration statement to include any
material information with respect to the plan of distribution not previously
disclosed in the  registration  statement or any material  change to such
information in the registration statement.

     (2)  That,  for  the  purpose  of  determining  any liability  under  the
Securities Act of 1933,each such post-effective amendment shall be deemed to be
a new registration statement relating to the securities offered therein,and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

     (3) To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of
the offering.

      (4) That, for purposes of determining any liability  under the Securities
Act of 1933, each filing of the  registrant's annual report pursuant to Section
13(a) or  Section  15(d) of the Securities  Exchange  Act of 1934  (and,  where
applicable, each filing of an employee benefit plan's annual report pursuant to
Section 15(d) of the Securities  Exchange Act of 1934) that is incorporated  by
reference in the registration statement shall be deemed to be a new
registration statement relating to the securities  offered therein,  and
the offering of such securities  at that time shall be deemed to be the
initial  bona fide  offering
thereof.

     (5) Insofar as indemnification for liabilities under the Securities Act of
1933 may be permitted to  directors, officers  and  controlling  persons of the
registrant pursuant to the foregoing provisions,  or otherwise,  the registrant
has been advised that in the opinion of the Securities and Exchange  Commission
such  indemnification is against public policy as expressed in the Act, and is,
therefore, unenforceable. In the event that a claim for indemnification against
such liabilities (other than the payment by the registrant of expenses incurred
or paid by a director, officer or  controlling  person of the registrant in the
successful  defense of any  action, suit or  proceeding)  is  asserted  by such
director, officer or controlling person in connection with the securities being
registered,the registrant will, unless in the opinion of its counsel the matter
has been  settled by  controlling  precedent, submit to a court of  appropriate
jurisdiction the question whether such indemnification  by it is against public
policy as expressed in the Act and will  be governed  by the final adjudication
of such issue.

                                   SIGNATURES

      Pursuant to the requirements of the Securities Act of 1933, the
registrant certifies that it has reasonable grounds to believe that it
meets all the requirements for filing  on Form S-8 and has duly caused this
registration statement to be signed on its behalf  by the undersigned,
thereunto duly authorized, in the Washington, D.C.

Dated: May 25, 2007

                                          ANGIOGENEX, INC.
                                          a Nevada corporation


                                          /s/ Richard Salvador, Ph.D.
                                          ---------------------------
                                              Richard Salvador, Ph.D.
                                              President, CEO




Pursuant to the requirements of the Securities Act of 1933, this report has
been signed below by the following persons on behalf of the Company and in the
capacities and on the dates indicated.


Date: May 25, 2007                        /s/ Richard Salvador, Ph.D.
                                          ---------------------------
                                              Richard Salvador, Ph.D.
                                              President, CEO


                                          /s/ Martin Murray
                                          -----------------------
                                              Martin Murray
                                              Chief Financial Officer,
                                              Secretary and Treasurer


                                          /s/ Michael M. Strage
                                          -----------------------
                                              Michael M. Strage
                                              Director