Guggenheim Funds Distributors, LLC 2455 Corporate West Drive Lisle, Illinois 60532 July 9, 2013 Securities and Exchange Commission 100 F Street NE Washington D.C. 20549 Re: Guggenheim Defined Portfolios, Series 1051 (the "Trust") (File Nos. 333-188251 & 811-03763) Ladies/Gentlemen: In connection with the response to the comments of the staff of the Securities and Exchange Commission (the "Commission") regarding the Registration Statement on Form S-6 for the registration under the Securities Act of 1933 and the Investment Company Act of 1940 of shares of beneficial interest of the Trust, we acknowledge that: 1. The Trust is responsible for the adequacy and accuracy of the disclosure in such Registration Statement; 2. Staff comments or changes to disclosure in response to staff comments in such Registration Statement reviewed by the staff do not foreclose the Commission from taking any action with respect to the Registration Statement; and 3. The Trust may not assert staff comments as a defense in any proceeding initiated by the Commission or any person under the federal securities laws of the United States. Very truly yours, Guggenheim Defined Portfolios, Series 1051 BY GUGGENHEIM FUNDS DISTRIBUTORS, LLC By /s/ Amy Lee --------------- Amy Lee Vice President and Secretary