Chapman and Cutler LLP 111 West Monroe Street Chicago, Illinois 60603 November 25, 2014 Mr. Edward Bartz Division of Investment Management Securities and Exchange Commission 100 F Street, N.E. Washington, DC 20549 Re: Guggenheim Defined Portfolios, Series 1246 Floating Rate & Dividend Growth Portfolio, Series 7 File Nos. 333-198858 and 811-03763 -------------------------------------------------------------------------------- Dear Mr. Bartz: This letter is in response to your comments given during a telephone conversation with our office regarding the registration statement on Form S-6 for Guggenheim Defined Portfolios, Series 1246, filed on September 19, 2014 with the Securities and Exchange Commission (the "Commission"). The registration statement offers the Floating Rate & Dividend Growth Portfolio, Series 7 (the "trust"). PROSPECTUS Investment Summary -- Principal Investment Strategy 1. Please add a maturity policy for the high-yield securities held by the closed-end funds or exchange-traded funds in the trust's portfolio. Response: The following has been added to the first paragraph of this section: "The sponsor will consider Closed-End Funds and ETFs investing in securities of all durations." Investment Summary -- Principal Risks 2. The "Principal Investment Strategy" section states that the Trust may invest in U.S.-listed foreign companies and in companies with all market capitalizations. Please add disclosure about the risks of investing in U.S.-listed foreign companies and small-capitalization companies in the "Principal Risks" section. Response: Even though U.S.-listed foreign company securities and small-capitalization securities may be included in the portfolio, we include risks based upon the final portfolio. If such securities are selected for the portfolio of this Trust, we will add the appropriate risk disclosures. 3. The duration example in the eighth bullet uses a duration of three years. Please confirm that the average weighted duration of the closed-end funds and exchange-traded funds is approximately three years or less. If not, please revise this example to reflect the average weighted duration of the underlying securities. Response: We confirm that the average weighted duration of the underlying securities is approximately three years or less and, therefore, the example does not need to be revised. We appreciate your prompt attention to this registration statement. If you have any questions or comments or would like to discuss our responses to your questions please feel free to contact the undersigned at (312) 845-3484. Very truly yours, CHAPMAN AND CUTLER LLP By /s/ Morrison C. Warren ------------------------- Morrison C. Warren