[ON CHAPMAN AND CUTLER LLP LETTERHEAD]

                             Chapman and Cutler LLP
                             111 West Monroe Street
                            Chicago, Illinois 60603


                               September 8, 2016

Mr. Edward Bartz
Division of Investment Management
Securities and Exchange Commission
100 F Street, N.E
Washington, DC  20549


                 Re: Guggenheim Defined Portfolios, Series 1500
      UBS Opportunistic Equity Income List: Equity Advisory Group, 2016-3,
                  Series 6 File Nos. 333-212931 and 811-03763
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Dear Mr. Bartz:

      This letter is in response to your comments given during a telephone
conversation with our office regarding the registration statement on Form S-6
for Guggenheim Defined Portfolios, Series 1500, filed on August 5, 2016, with
the Securities and Exchange Commission (the "Commission"). The registration
statement proposes to offer the UBS Opportunistic Equity Income List: Equity
Advisory Group, 2016-3, Series 6 (the "Trust").

PROSPECTUS

Investment Summary -- Security Selection

      1. The second sentence of the first paragraph of this section states that
"the UBS 'Opportunistic Equity Income' criteria begins with a universe of all
dividend-paying companies traded in the United States as of the date of the
security selection." Please revise the term "dividend-paying companies" to state
that the criteria begins with a universe of all "dividend-paying equity
securities."

      Response: The disclosure has been revised in response to your comment.

      2. The first bullet in the first paragraph states that the minimum market
capitalization for securities in the Trust is $2 billion. Please include risk
disclosure related to small-capitalization securities.

      Response: The sponsor believes that small-capitalization securities have a
market capitalization under $2 billion. The risk disclosure has been revised to
disclose the Trust's potential investment in mid-capitalization securities.

      3. The fourth bullet point in the first paragraph of this section states
that securities may have split ratings on different UBS platforms. Please
disclose which UBS platforms will be used to determine the ratings of the
securities.

      Response: The disclosure has been revised in response to your comment.

      4. The second paragraph of this section states that companies are chosen
from a sub-universe. Please state whether the sub-universe is from a stock list
and if so, which stock list is used.

      Response: The disclosure has been revised in response to your comment.

      We appreciate your prompt attention to this registration statement. If you
have any questions or comments or would like to discuss our responses to your
questions please feel free to contact the undersigned at (312) 845-3484.

                                                               Very truly yours,

                                                          CHAPMAN AND CUTLER LLP


                                                       By /s/ Morrison C. Warren
                                                       -------------------------
                                                              Morrison C. Warren