Chapman and Cutler LLP
                             111 West Monroe Street
                             Chicago, Illinois 60603


                                October 12, 2016


Mr. Edward Bartz
Division of Investment Management
Securities and Exchange Commission
100 F Street, N.E.
Washington, DC  20549


                 Re: Guggenheim Defined Portfolios, Series 1529
              Floating Rate & Dividend Growth Portfolio, Series 13
                       File Nos. 333-213486 and 811-03763
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Dear Mr. Bartz:

     This letter is in response to your comment given during a telephone
conversation with our office regarding the registration statement on Form S-6
for Guggenheim Defined Portfolios, Series 1529, filed on September 2, 2016, with
the Securities and Exchange Commission (the "Commission"). The registration
statement proposes to offer the Floating Rate & Dividend Growth Portfolio,
Series 13 (the "Trust").

PROSPECTUS

Investment Summary -- Principal Risks

     1. The duration example in the eighth bullet uses a duration of three
years. Please confirm that the average weighted duration of the fixed-income
securities held by the underlying securities is approximately three years or
less. If not, please revise this example to reflect the average weighted
duration of the underlying securities.

     Response: We confirm that the average weighted duration of the fixed-income
securities held by the underlying securities is approximately three years or
less and, therefore, the example does not need to be revised.

     We appreciate your prompt attention to this registration statement. If you
have any questions or comments or would like to discuss our responses to your
questions please feel free to contact the undersigned at (312) 845-3484.

                                                               Very truly yours,

                                                          CHAPMAN AND CUTLER LLP


                                                       By /s/ Morrison C. Warren
                                                       -------------------------
                                                              Morrison C. Warren