Chapman and Cutler LLP 111 West Monroe Street Chicago, Illinois 60603 October 3, 2017 Mr. Edward Bartz Division of Investment Management Securities and Exchange Commission 100 F Street, N.E. Washington, DC 20549 Re: Guggenheim Defined Portfolios, Series 1678 Convertible & Income Portfolio of Funds, Series 27 File Nos. 333-220192 and 811-03763 ------------------------------------------------------------------------------- Dear Mr. Bartz: This letter is in response to your comment given during a telephone conversation with our office regarding the registration statement on Form S-6 for Guggenheim Defined Portfolios, Series 1678, filed on August 28, 2017, with the Securities and Exchange Commission (the "Commission"). The registration statement proposes to offer the Convertible & Income Portfolio of Funds, Series 27 (the "Trust"). PROSPECTUS Investment Summary -- Principal Risks 1. The duration example in the sixth bullet uses a duration of five years. Please confirm that the average weighted duration of the fixed-income securities held indirectly by the Trust is approximately five years or less. If not, please revise this example to reflect the average weighted duration of the fixed-income securities. Response: The sponsor confirm that the average weighted duration of the fixed-income securities held indirectly by the Trust is approximately five years or less and, therefore, the example does not need to be revised. We appreciate your prompt attention to this registration statement. If you have any questions or comments or would like to discuss our responses to your questions, please feel free to contact the undersigned at (312) 845-3484. Very truly yours, CHAPMAN AND CUTLER LLP By /s/ Morrison C. Warren ------------------------- Morrison C. Warren