Chapman and Cutler LLP
111 West Monroe Street
Chicago, Illinois 60603
March 5, 2020
VIA EDGAR FILING
Mr. Edward Bartz
Division of Investment Management
Securities and Exchange Commission
100 F Street, N.E.
Washington, DC 20549
Re: Guggenheim Defined Portfolios, Series 2001
Global Balanced Income Builder Portfolio, Series 15
File Nos. 333-236113 and 811-03763
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Dear Mr. Bartz:
This letter responds to your comment given during a telephone conversation
with our office regarding the registration statement on Form S-6 for Guggenheim
Defined Portfolios, Series 2001, filed on January 28, 2020 with the Securities
and Exchange Commission (the "Commission"). The registration statement proposes
to offer the Global Balanced Income Builder Portfolio, Series 15 (the "Trust").
PROSPECTUS
Investment Summary -- Principal Investment Strategy
1. The "Principal Risks" section states that the Trust invests in
exchange-traded funds that invest in mortgage-backed securities. Please disclose
this in the "Principal Investment Strategy" section.
Response: In response to this comment, the last sentence of the "Principal
Investment Strategy" section will be revised to the following: "Finally, the
fixed-income ETFs included in the portfolio may invest fixed-income securities
that include, but are not limited to, mortgage-backed securities, municipal
bonds and debt securities issued by foreign companies, including companies
located in emerging markets."
We appreciate your prompt attention to this registration statement. If you
have any questions or comments or would like to discuss our responses to your
questions, please feel free to contact the undersigned at (312) 845-3484.
Very truly yours,
CHAPMAN AND CUTLER LLP
By /s/ Morrison C. Warren
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Morrison C. Warren