Exhibit 32.1:  Certification of Chief Executive Officer and Chief Financial
               Officer under Section 1350 as Adopted Pursuant Section 906 of
               the Sarbanes-Oxley Act



               CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350
                           AS ADOPTED PURSUANT TO
                SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

The undersigned officer of Signal Advance, Inc. (the "Company"), hereby
certifies, to such officer's knowledge, that the Company's Quarterly Report
on Form 10-Q for the six months ended June 30, 2014 (the "Report") fully
complies with the requirements of Section 13(a) of the Securities Exchange
Act of 1934 and that the information contained in the Report fairly presents,
in all material respects, the financial condition and results of operations
of the Company.



     /s/Chris M. Hymel

     Chris M. Hymel
     President/Treasurer


August 14, 2014