POWER OF ATTORNEY

	Know all by these presents that the undersigned hereby
constitutes and appoints each of Thomas A. Allen and
Andrew J. Gibbons, and each of them acting alone, signing
singly, the undersigned's true and lawful attorney-in-fact
to:

(1) execute for and on behalf of the undersigned, in the
undersigned's capacity as an officer, director, and/or 10%
or more stockholder of Clearside Biomedical , Inc. (the
"Company"), Forms ID, 3, 4 and 5 and Schedules 13D or 13G
(and any amendments thereto) under Section 13(d) and 16(a)
of the Securities Exchange Act of 1934, as amended (the
"1934 Act") in accordance with the 1934 Act, and the rules
promulgated thereunder;

(2) do and perform any and all acts for and on behalf of the
undersigned which may be necessary or desirable to complete
and execute any such Form or Schedule (and any amendments
thereto) and to file timely such Form or Schedule with the
United States Securities and Exchange Commission and any
stock exchange or similar authority; and

(3) take any other action of any type whatsoever in connection
with the foregoing which in the opinion of such attorney-in-
fact may be of benefit to, in the best interest of, or
legally required by, the undersigned, it being understood that
the documents executed by such attorney-in-fact on behalf of
the undersigned pursuant to this Power of Attorney shall be in
such form and shall contain such terms and conditions as such
attorney-in-fact may approve in such attorney-in-fact's
discretion.

	The undersigned hereby grants to each such attorney-in-
fact full power and authority to do and perform any and every
act and thing whatsoever requisite, necessary or proper to be
done in the exercise of any of the rights and powers herein
granted, as fully to all intents and purposes as the
undersigned might or could do if personally present, with full
power of substitution or revocation, hereby ratifying and
confirming all that such attorney-in-fact, or such attorney-
in-fact's substitute or substitutes, shall lawfully do or
cause to be done by virtue of this power of attorney and the
rights and powers herein granted.  The undersigned acknowledges
that the foregoing attorneys-in-fact, in serving in such
capacity at the request of the undersigned, are not assuming,
nor is the Company assuming, any of the undersigned's
responsibilities to comply with Section 13(d) or 16(a) of the
1934 Act.

	This Power of Attorney shall remain in full force and
effect until the undersigned is no longer required to file such
Forms or Schedules with respect to the undersigned's holdings
of and transactions in securities issued by the Company, unless
earlier revoked by the undersigned in a signed writing
delivered to each of the foregoing attorneys-in-fact.

	IN WITNESS WHEREOF, the undersigned has caused this Power
of Attorney to be executed as of this 18th day of January 2017.


HATTERAS VENTURE ADVISORS IV SBIC, LLC

By:  /s/ Clay B. Thorp
Name: 	Clay B. Thorp
Title: 	Manager


HATTERAS VENTURE PARTNERS IV SBIC, LP

By:  Hatteras Venture Advisors IV SBIC, LLC, its general
partner

By:	/s/ Clay B. Thorp
Name: 	Clay B. Thorp
Title: 	Manager


/s/ John C. Crumpler
John C. Crumpler


/s/ Robert A. Ingram
Robert A. Ingram


/s/ Kenneth B. Lee
Kenneth B. Lee


/s/ Douglas Reed
Douglas Reed


/s/ Clay B. Thorp
Clay B. Thorp