UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                   FORM 12b-25

                           NOTIFICATION OF LATE FILING

                        Commission File Number: 811-23631

     (Check One): [ ] Form 10-K and Form 10-KSB [ ] Form 20-F [ ] Form 11-K
           [ ] Form 10-Q and Form 10-QSB [ ] Form N-SAR [X] Form N-CSR

                       For Period Ended: December 31, 2021


                       [ ] Transition Report on Form 10-K

                       [ ] Transition Report on Form 20-F

                       [ ] Transition Report on Form 11-K

                       [ ] Transition Report on Form 10-Q

                       [ ] Transition Report on Form N-SAR

                For the Transition Period Ended: _______________


         Nothing in this form shall be construed to imply that the Commission
has verified any information contained herein.

         If the notification relates to a portion of the filing checked above,
identify the Item(s) to which the notification relates:



                         PART I - REGISTRANT INFORMATION


                    Tactical Investment Series Trust
         ---------------------------------------------------------------
                            (Full Name of Registrant)


         ---------------------------------------------------------------
                           (Former Name if Applicable)

                            11726 Seven Gables Road
         ---------------------------------------------------------------
                     (Address of Principal Executive Office)

                            Cincinnati, OH 45249
         ---------------------------------------------------------------
                           (City, State and Zip Code)

                       PART II - RULE 12b-25 (b) AND (c)

         If the subject report could not be filed out without unreasonable
effort or expense and the registrant seeks relief pursuant to Rule 12b-25(b),
the following should be completed. (Check box if appropriate)

[X]     (a)       The reasons described in reasonable detail in Part III of this
                  form could not be eliminated without unreasonable effort or
                  expense;

[X]     (b)       The subject annual report, semi-annual report, transition
                  report on Form 10-K, Form 20-F, Form 11-K, Form
                  N-SAR or Form N-CSR, or portion thereof, will be filed on or
                  before the fifteenth calendar day following the prescribed due
                  date; or the subject quarterly portion thereof, will be filed
                  on or before the fifth calendar day following the prescribed
                  due date; and

[ ]     (c)       The accountant's statement or exhibit required by Rule
                  12b-25(c) has been attached if applicable.

                              PART III - NARRATIVE

         State below in reasonable detail the reasons why Forms 10-K,
20-F, 11-K, 10-Q, 10-D, N-SAR, N-CSR, or the transition report or
portion thereof, could not be filed within the prescribed time period.


        The Tactical Investment Series Trust is unable to file its Annual Report
        for the TFA Tactical Income Fund, Tactical Moderate Allocation Fund,
        Tactical Growth Allocation Fund, TFA Quantitative Fund, TFA
        Multidimensional Fund and TFA AlphaGen Growth Fund on Form N-CSR for the
        year ended December 31, 2021 (the "Annual Report") without unreasonable
        effort and expense because it requires more time to compile and review
        the information included in the Annual Report.   This was due to a
        delay in receiving certain files from the prior administrator. The
        Trust anticipates that it will file the Annual Report on Form N-CSR
        on or before the fifteenth calendar day following the prescribed
        due date.



                           PART IV - OTHER INFORMATION

(1)      Name and telephone number of persons to contact in regard to this
         notification.

             Brian Curley              631                 470-2720
         ---------------------     ---------------      ------------------
                (Name)               (Area Code)        (Telephone Number)

(2)      Have all other periodic reports required under Section 13 or 15(d) of
         the Securities Exchange Act of 1934 or Section 30 of the Investment
         Company Act of 1940 during the preceding 12 months or for such shorter
         period that the registrant was required to file such report(s) been
         filed? If the answer is no, identify report(s). [X] Yes [ ] No



(3)      Is it anticipated that any significant changes in results of operations
         from the corresponding period for the last fiscal year will be
         reflected by the earnings statements to be included in the subject
         report or in the portion thereof? [ ] Yes [X] No

         If so, attach an explanation of the anticipated change, both
         narratively and quantitatively, and, if appropriate, state the reasons
         why a reasonable estimate of the results cannot be made.



                    Tactical Investment Series Trust
         ---------------------------------------------------------------
                (Name of Registrant as specified in its charter)

has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.



Date: March 16, 2022                /s/ Brian Curley
                                   -------------------------
                                   Name: Brian Curley
                                   Title: Treasurer