426 patents
Page 13 of 22
Utility
Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation
19 Oct 21
Methods for preparing labeled glycosylamines from a complex matrix are provided.
Matthew A. Lauber
Filed: 19 Jun 17
Utility
Dynamically Adjusting Set Points for a Heating/cooling Element of a Chromatography Column Using Available Information
14 Oct 21
The exemplary embodiments may determine a temperature set point for an outlet heater or cooler based on available information without requiring user input or requiring only minimal user input.
Michael O. Fogwill, Jason F. Hill, Fabrice Gritti
Filed: 14 Apr 21
Utility
Ion Detector
14 Oct 21
An ion detector comprises a surface configured to receive one or more ions and a detector configured to detect one or more ions by detecting electromagnetic radiation scattered by one or more ions at the surface.
Joseph A. Jarrell, Martin Gilar
Filed: 8 Apr 21
Utility
Coaxial Introduction of Calibrant In a Flow Path with Analyte to an Ion Source
14 Oct 21
Exemplary embodiments may deploy a valve that introduces a sample of a calibrant coaxially with flow exiting a source of a mobile phase flow, such as a liquid chromatography (LC) column, on a path to an ion source for the mass spectrometer (MS).
Michael O. Fogwill, Joseph D. Michienzi, Sylvain Gilles Cormier
Filed: 14 Apr 21
Utility
Systems, methods and devices for decreasing solubility problems in chromatography
12 Oct 21
A significant reduction in extra-column band broadening can be achieved by decoupling the injection system from the main solvent flow line.
Abhijit Tarafder
Filed: 19 Oct 16
Utility
Systems, devices, and methods for controlling the temperature of a CO2 pump
12 Oct 21
Methodologies, systems, and computer-readable media are provided for controlling the mass flow rate within a CO2 based chromatography system.
Abhijit Tarafder, Jason Hill, Joshua Shreve
Filed: 26 Oct 18
Utility
Method and an apparatus for analyzing a complex sample
5 Oct 21
A method of analyzing a complex sample includes performing a sequential chromatographic-IMS-MS analysis of a sample to obtain a plurality of experimental mass spectra having isotopic clusters, wherein each spectrum of the plurality of spectra is associated with a chromatographic retention time and an ion-mobility drift time.
Scott J. Geromanos, Marc V. Gorenstein, Daniel Golick, Steven J. Ciavarini
Filed: 19 May 20
Utility
Devices and Methods for the Sensitive Detection and Quantitation of Biomolecules
30 Sep 21
The present disclosure provides devices, systems, kits and methods useful for quantitation of biomolecules such as intact proteins and nucleic acids.
Jennifer M. Nguyen, Matthew A. Lauber, Yun Wang Alelyunas, Gregory T. Roman, Henry Y. Shion
Filed: 24 Mar 21
Utility
Sample Automation Manager
30 Sep 21
A liquid chromatography system includes a solvent delivery system, a sample manager including a sample delivery system in fluidic communication with the solvent delivery system, the sample delivery system configured to inject a sample from a sample-vial into a chromatographic flow stream, a liquid chromatography column located downstream from the sample delivery system, and a detector located downstream from the liquid chromatography column.
Sylvain Gilles Cormier, Joseph D. Antocci, Francis Patrick Tracey, Charles H. Phoebe, JR.
Filed: 23 Mar 21
Utility
Large Volume Sample Injection for Liquid Chromatography
30 Sep 21
Described are methods and fluidic networks for injecting a sample into a liquid chromatography system.
Sylvain Gilles Cormier, Jason F. Hill
Filed: 24 Mar 21
Utility
Metering Pump for Liquid Chromatography
30 Sep 21
Described is a metering pump that may be used to meter volumes of sample in a chromatography system.
Joshua A. Burnett, Rose Solow, David A. Simpson, Peter Osswald, John M. Auclair, Michael LeBeau
Filed: 25 Mar 21
Utility
Hybrid gradient delivery system and operation
28 Sep 21
A solvent delivery system for a liquid chromatography system may include a first gradient proportioning valve in fluidic communication with a first plurality of sources of solvent and producing therefrom a first low-pressure gradient stream.
Joseph A. Luongo, Craig Hamilton Dobbs
Filed: 12 Mar 19
Utility
Sample Manager, System and Method
23 Sep 21
A liquid chromatography sample manager includes a sampling mechanism; a sample platter mounted in the sampling mechanism, the sample platter configured to rotate about a first vertical axis; a needle arm mounted within the sampling mechanism, the needle arm configured to rotate about a second vertical axis; and a sample delivery system in fluidic communication with solvent delivery system, the sample delivery system including a sample needle attached to the needle arm, the sample delivery system configured to transfer a first sample from a first sample vial carrier located in the sample platter into a chromatographic flow stream.
Joshua A. Burnett, Rose Solow, David A. Simpson, Marc E. Lemelin
Filed: 16 Mar 21
Utility
High Throughput Affinity Sample Preparation for Mycotoxin Analysis
23 Sep 21
The present disclosure relates to a method of separating a sample including a mycotoxin.
Lingyun Chen, Jianmin Liu
Filed: 17 Mar 21
Utility
Needle Drive, System and Method
23 Sep 21
A liquid chromatography sample manager includes a thermal chamber, a sample platter mounted in the thermal chamber, and a needle drive including a base having a shaft configured to rotate about a vertical axis, the base attachable to an interior of a sample manager of a liquid chromatography system.
Joshua A. Burnett, Rose Solow, David A. Simpson, Marc E. Lemelin
Filed: 16 Mar 21
Utility
Purification elements for dispensing a purified liquid
21 Sep 21
In various aspects provided are purification media and containers for dispensing a purified liquid are provided herein where a high surface area-to-volume chemically interactive purification media positioned at the outlet of a container that purifies the liquid as it is dispensed and/or extracted.
Moon Chul Jung, Abhijit Tarafder, Wade P. Leveille
Filed: 18 Dec 18
Utility
Determination of dynamic parameters for adaptive actuator control
14 Sep 21
An actuator control system, mechanical testing system, and method for adaptive control of an actuator of a mechanical testing device is provided.
Kevin Alstrin
Filed: 2 Oct 18
Utility
Purification and Isolation of Synthetic Oligonucleotides Using Hydrophilic-interaction Liquid Chromatography
9 Sep 21
Methods of purifying targeted oligonucleotides within a reaction mixture using hydrophilic interaction liquid chromatography (HILIC) is disclosed.
Jo-Ann Jablonski, Catalin Doneanu
Filed: 4 Mar 21
Utility
DMD based UV absorption detector for liquid chromatography
7 Sep 21
A detector for use in liquid chromatography is provided.
Anthony C. Jeannotte, Daniel Gillund, Aditya Shankar Prasad, Saksham Saxena
Filed: 9 Oct 19
Utility
On-line sampling from a process source
7 Sep 21
An online sample manager of a liquid chromatography system includes a fluidic tee having a first inlet port, a second inlet port, and an outlet port.
Sylvain Cormier
Filed: 10 Feb 11