196 patents
Page 7 of 10
Utility
Hybrid gradient delivery system and operation
28 Sep 21
A solvent delivery system for a liquid chromatography system may include a first gradient proportioning valve in fluidic communication with a first plurality of sources of solvent and producing therefrom a first low-pressure gradient stream.
Joseph A. Luongo, Craig Hamilton Dobbs
Filed: 12 Mar 19
Utility
Purification elements for dispensing a purified liquid
21 Sep 21
In various aspects provided are purification media and containers for dispensing a purified liquid are provided herein where a high surface area-to-volume chemically interactive purification media positioned at the outlet of a container that purifies the liquid as it is dispensed and/or extracted.
Moon Chul Jung, Abhijit Tarafder, Wade P. Leveille
Filed: 18 Dec 18
Utility
Determination of dynamic parameters for adaptive actuator control
14 Sep 21
An actuator control system, mechanical testing system, and method for adaptive control of an actuator of a mechanical testing device is provided.
Kevin Alstrin
Filed: 2 Oct 18
Utility
On-line sampling from a process source
7 Sep 21
An online sample manager of a liquid chromatography system includes a fluidic tee having a first inlet port, a second inlet port, and an outlet port.
Sylvain Cormier
Filed: 10 Feb 11
Utility
DMD based UV absorption detector for liquid chromatography
7 Sep 21
A detector for use in liquid chromatography is provided.
Anthony C. Jeannotte, Daniel Gillund, Aditya Shankar Prasad, Saksham Saxena
Filed: 9 Oct 19
Utility
Compression fitting with coupled ferrule
31 Aug 21
The invention provides compression fittings and methods of assembling compression fittings.
Sylvain Cormier, Kurt D. Joudrey, Joshua A. Shreve
Filed: 7 May 14
Utility
Method and apparatus for injecting a chromatographic sample
31 Aug 21
A method for injecting a diluted sample in a chromatography system includes merging a flow of a sample and a flow of a diluent to form a flow of a diluted sample.
Martin Gilar, Richard W. Andrews, Peyton C. Beals, Thomas McDonald, Keith Fadgen, Jordan Kornfeld, Geoff Gerhardt, Sylvain Cormier
Filed: 4 May 17
Utility
Systems, methods and devices for reducing band dispersion in chromatography
24 Aug 21
Reduced column loading of a sample onto a chromatographic column may be mitigated by excluding diffuse portions of the sample from introduction to the column.
Abhijit Tarafder, Pamela C. Iraneta
Filed: 7 Mar 17
Utility
Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
17 Aug 21
The invention relates to poly-amide bonded hydrophilic interaction chromatography (HILIC) stationary phases and novel HILIC methods for use in the characterization of large biological molecules modified with polar groups, known to those skilled in the art as glycans.
Matthew A. Lauber, Stephan M. Koza, Pamela C. Iraneta, Kevin D. Wyndham
Filed: 2 Apr 15
Utility
Polar pesticide determination using chromatography
17 Aug 21
The present disclosure relates to the determination of pesticides, e.g., polar pesticides, in a sample using chromatography.
Dimple D. Shah, Jacob N. Fairchild, Euan Ross, Benjamin Wuyts
Filed: 7 Mar 18
Utility
Devices and methods for analyzing intact proteins, antibodies, antibody subunits, and antibody drug conjugates
17 Aug 21
The present disclosure relates devices and methods for analyzing intact antibodies, antibody subunits, antibody drug conjugate subunits, antibody drug conjugates, and intact proteins in a biological mixture.
Gregory T. Roman, James P. Murphy
Filed: 27 Feb 18
Utility
Techniques for monitoring chromatographic fluid flows
10 Aug 21
Various embodiments are generally directed to techniques for monitoring chromatographic fluid flows, such as the flow to and/or from one or more reservoirs used in chromatographic operations, for instance.
Abhijit Tarafder, Jonathan Belanger, Moon Chul Jung, Wade P. Leveille
Filed: 12 Jun 19
Utility
Systems and methods for chromatographic analysis
3 Aug 21
Methods of chromatographic detection are provided that include the step of providing a chromatography instrument without an autosampler, an external device, a pressurized sample injection device and a chromatographic data system.
Aaron D. Phoebe, Sylvain G. Cormier, Charles H. Phoebe, Jr.
Filed: 24 Sep 18
Utility
Continuous determination of medium stiffness and load gain for adaptive actuator control
3 Aug 21
An actuator control system, mechanical testing system, and method for adaptive control of an actuator of a mechanical testing device may include determining a stiffness of a medium that the actuator is moving through and/or load gain of the actuator, wherein the stiffness and load gain is determined by generating a waveform to actuate the actuator until a load sensor signal and/or a displacement sensor signal is received, and controllably moving the actuator through the medium according to a predefined constant velocity by calculating a current request using the stiffness of the medium, and/or adjusting the load of the actuator in accordance with a constant load ramp rate.
Kevin Alstrin
Filed: 2 Oct 18
Utility
Porous carbon-heteroatom-silicon inorganic/organic materials for chromatographic separations and process for the preparation thereof
27 Jul 21
The present disclosure provides porous carbon-heteroatom-silicon inorganic/organic homogenous copolymeric hybrid materials, methods for their preparation, and uses thereof, e.g., as chromatographic separations materials.
Kevin D. Wyndham, John E. O'Gara
Filed: 16 Jan 17
Utility
Chromatographic materials
13 Jul 21
In one aspect, the present invention provides a chromatographic stationary phase material for various different modes of chromatography represented by Formula 1: [X](W)a(Q)b(T)c (Formula 1).
Kevin D. Wyndham, Michael F. Morris, Darryl W. Brousmiche, Jason F. Hill, Jacob N. Fairchild
Filed: 20 Mar 19
Utility
Method and apparatus for injecting a chromatographic sample
13 Jul 21
Described are a method and apparatus for diluting a chromatographic sample.
Martin Gilar, Keith Fadgen, Peyton C. Beals, Sylvain Gilles Cormier, Richard Wayne Andrews, Geoff C. Gerhardt, Jordan Kornfeld, Thomas S. McDonald
Filed: 15 Oct 19
Utility
Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals
13 Jul 21
Novel reagents comprising MS active, fluorescent compounds having an activated functionality for reaction with aldehydes and useful in labeling biomolecules such as glycans and methods of making the same are taught and described.
Darryl W. Brousmiche, Matthew A. Lauber
Filed: 19 Jun 17
Utility
High surface area chromatographic device with low pressure drop
22 Jun 21
A chromatographic device includes a primary channel having a cross-sectional area and characteristic length such that analyte travel within the primary channel is substantially convective.
Abhijit Tarafder, Moon Chul Jung, Edouard S. P. Bouvier
Filed: 5 Mar 19
Utility
Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties
15 Jun 21
Solutions, detection methods and chromatographic systems are provided for electrospray ionization of glycans modified with amphipathic, strongly basic moieties.
Darryl W. Brousmiche, Matthew A. Lauber
Filed: 19 Jun 17