13 patents
Utility
MORPHIC FORMS OF 4-AMINO-7-(3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-2-METHYL-7H-PYRROLO[2,3-d]PYRIMIDINE-5-CARBOXAMIDE AND USES THEREOF
14 Jul 22
The present disclosure relates to crystalline morphic forms of 4-amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide.
Roy W. WARE, Venkat LAKSHMANAN, Aaron Leigh DOWNEY
Filed: 4 Aug 21
Utility
Morphic Forms of Hexadecyloxypropyl-phosphonate Esters and Methods of Synthesis Thereof
12 May 22
The disclosure describes methods of synthesis of phosphonate ester compounds.
Roy Wendell WARE, Aaron Leigh DOWNEY
Filed: 16 Jun 21
Utility
G Protein-coupled Receptor (GPCR) Modulation by Imipridones
10 Mar 22
Imipridones has been found to selectively modulate Class A G protein-coupled receptors (GPCRs), such as the D2-like subfamily of dopamine receptors, and to be useful for the treatment of conditions and disorders in need of such modulation, such as cancers, psychiatric disorders, and bacterial infections.
Joshua E. ALLEN, Martin STOGNIEW, Varun Vijay PRABHU
Filed: 29 Jul 21
Utility
7-BENZYL-4-(2-METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZO [1,2-a]PYRIDO[3,4-e]PYRIMIDIN-5(1H)-ONE, ANALOGS THEREOF, AND SALTS THEREOF AND METHODS FOR THEIR USE IN THERAPY
20 Jan 22
Joshua E. ALLEN, Martin STOGNIEW, Richard S. POTTORF, Bhaskara Rao NALLAGANCHU, Gary OLSON, Yanjun SUN
Filed: 24 Jun 21
Utility
Pyrrolopyrimidine Nucleosides and Analogs Thereof
6 Jan 22
John Henry BOUGHER, III, Ramamurty V S CHANGALVALA, Aaron Leigh DOWNEY, John C. DRACH, Ernest Randall LANIER, JR., Andrew Louis MCIVER, Bradley David ROBERTSON, Dean Wallace SELLESETH, Phiroze Behram SETHNA, Leroy TOWNSEND, Roy W. WARE
Filed: 27 Jan 21
Utility
Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide and uses thereof
7 Sep 21
The present disclosure relates to crystalline morphic forms of 4-amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide.
Roy W. Ware, Venkat Lakshmanan, Aaron Leigh Downey
Filed: 21 Sep 18
Utility
Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
20 Jul 21
The disclosure describes methods of synthesis of phosphonate ester compounds.
Roy Wendell Ware, Aaron Leigh Downey
Filed: 11 Oct 19
Utility
Pyrrolopyrimidine nucleosides and analogs thereof
9 Mar 21
John Henry Bougher, III, Ramamurty V S Changalvala, Aaron Leigh Downey, John C. Drach, Ernest Randall Lanier, Jr., Andrew Louis McIver, Bradley David Robertson, Dean Wallace Selleseth, Phiroze Behram Sethna, Leroy Townsend, Roy W. Ware
Filed: 6 Aug 19
Utility
MORPHIC FORMS OF 4-AMINO-7-(3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-2-METHYL-7H-PYRROLO[2,3-d]PYRIMIDINE-5-CARBOXAMIDE AND USES THEREOF
2 Sep 20
The present disclosure relates to crystalline morphic forms of 4-amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide.
Roy W. WARE, Venkat LAKSHMANAN, Aaron Leigh DOWNEY
Filed: 20 Sep 18
Utility
Pyrrolopyrimidine Nucleosides and Analogs Thereof
24 Jun 20
John Henry BOUGHER, III, Ramamurty V S CHANGALVALA, Aaron Leigh DOWNEY, John C. DRACH, Ernest Randall LANIER, Jr., Andrew Louis MCIVER, Bradley David ROBERTSON, Dean Wallace SELLESETH, Phiroze Behram SETHNA, Leroy TOWNSEND, Roy W. WARE
Filed: 5 Aug 19
Utility
Formulations of Brincidofovir
6 May 20
Disclosed are formulations comprising brincidofovir.
Mohammed Anowrul KABIR, Odin Johann NADERER, Irma Marisa GROSSI
Filed: 19 Dec 19
Utility
Morphic Forms of Hexadecyloxypropyl-phosphonate Esters and Methods of Synthesis Thereof
25 Mar 20
The disclosure describes methods of synthesis of phosphonate ester compounds.
Roy Wendell WARE, Aaron Leigh DOWNEY
Filed: 10 Oct 19
Utility
Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
25 Nov 19
The disclosure describes methods of synthesis of phosphonate ester compounds.
Roy Wendell Ware, Aaron Leigh Downey
Filed: 18 Sep 18
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