100 patents
Utility
Multiple Analyte Fecal Antigen Testing
18 Jan 24
Methods, compositions, and systems for testing fecal samples, including small human fecal samples, for a plurality of different marker analytes, e.g., a plurality of different human protein, nucleic acid, and other molecular marker analytes.
Keith D. Fourrier, Michael J. Domanico, Stephanie M. Weber, Tanya M. Quint, Graham P. Lidgard
Filed: 16 Oct 20
Utility
Detecting gastric neoplasm
2 Jan 24
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.
David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Hatim T. Allawi
Filed: 5 Feb 20
Utility
Detecting Prostate Cancer
28 Dec 23
Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
Filed: 24 May 23
Utility
Methylation Assay
21 Dec 23
A method for detecting a methylated genomic locus is provided.
Graham P. Lidgard, Michael J. Domanico, Hatim Allawi, Hongzhi Zou
Filed: 12 May 23
Utility
Fecal sample processing and analysis comprising detection of blood
19 Dec 23
A method of processing a fecal sample from a human subject comprising removing a portion of a collected fecal sample and adding the removed portion of the sample to a buffer that prevents denaturation or degradation of blood proteins found in the sample, and detecting the presence of human blood in the removed portion of the fecal sample.
Joost Louwagie
Filed: 27 Jun 17
Utility
Mutation detection assay
19 Dec 23
A method of sample analysis is provided.
Hongzhi Zou, Graham P. Lidgard, Michael J. Domanico, Hatim Allawi
Filed: 8 Jul 21
Utility
Isolation and Detection of Dna from Plasma
7 Dec 23
Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA.
Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
Filed: 1 May 23
Utility
Detecting neoplasm
21 Nov 23
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
David A. Ahlquist, John B. Kisiel, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
Filed: 12 May 20
Utility
Modification of DNA on magnetic beads
14 Nov 23
Provided herein is technology related to the chemical modification and purification of DNA.
Michael J. Domanico, Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Oliver Hunt, Tobias Charles Zutz
Filed: 29 May 20
Utility
Synthetic Nucleic Acid Control Molecules
9 Nov 23
The present invention provides synthetic DNA strands that find use as controls or in nucleic acid testing methods.
Ilse A. Tyler, Keith Yaeger, Michael J. Domanico, Hatim Allawi, Graham P. Lidgard
Filed: 1 May 23
Utility
Ergonomic stool specimen container and enclosing holder systems, methods, and kits
31 Oct 23
Provided herein is technology relating to collecting and containing samples and particularly, but not exclusively, to technology for collecting and containing a stool specimen.
Joseph E. Schiestle, Krystal A. Burger, Timothy A. Parmer, Jad A. Lunde, Sam M. Jang, David A. Schuelke, David B. Wolgemuth, Jing Yang Lu
Filed: 6 Nov 20
Utility
Fecal Sample Processing and Analysis Comprising Detection of Blood
5 Oct 23
A method of processing a fecal sample from a human subject comprising combining a first portion of a collected fecal sample with a stabilizing buffer, combining a second portion of the sample with a solution that prevents denaturation or degradation of blood proteins found in a fecal sample.
Joost Louwagie
Filed: 7 Mar 23
Utility
Compositions comprising ZDHHC1 DNA in a complex
5 Sep 23
Provided herein is technology relating compositions and methods for detecting tissue cell-specific DNA, such as epithelial cell-specific DNA, in blood or blood products from a subject.
Hatim T. Allawi, Graham P. Lidgard
Filed: 28 Oct 19
Utility
Fecal Sample Processing and Analysis Comprising Detection of Blood
31 Aug 23
A method of processing a fecal sample from a human subject comprising combining a first portion of a collected fecal sample with a stabilizing buffer that maintains DNA integrity in a fecal sample, and combining a second portion of the sample with a solution that prevents denaturation or degradation of blood proteins found in a fecal sample.
Joost Louwagie
Filed: 7 Mar 23
Utility
Normalization of polymerase activity
25 Jul 23
Provided herein is technology relating to the amplification-based detection of nucleic acids and particularly, but not exclusively, to methods and compositions for minimizing variability in the activity between different samples or manufacturing lots of DNA polymerases, such as Taq DNA polymerase.
Hatim Allawi, Rebecca Oldham-Haltom, Zubin Gagrat, Michael Domanico, Graham Lidgard
Filed: 11 Feb 21
Utility
Detecting ovarian cancer
18 Jul 23
Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Michael W. Kaiser
Filed: 30 Oct 20
Utility
Method for stabilizing hemoglobin and reagents for performing the same
18 Jul 23
A stool resuspension solution comprising a hemoglobin stabilization reagent is provided.
Keith D. Fourrier, Jacquelyn T. Hennek, Michael J. Domanico, William G. Weisburg, Graham P. Lidgard, Kathleen S. Harings, Daniel J. Simpson
Filed: 6 Jun 22
Utility
Method for Stabilizing Hemoglobin and Reagents for Performing the Same
13 Jul 23
A stool resuspension solution comprising a hemoglobin stabilization reagent is provided.
Keith D. Fourrier, Jacquelyn T. Hennek, Michael J. Domanico, William G. Weisburg, Graham P. Lidgard, Kathleen S. Harings, Daniel J. Simpson
Filed: 24 Jan 23
Utility
Detecting prostate cancer
11 Jul 23
Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
Filed: 8 Jan 21
Utility
Methylation assay
27 Jun 23
A method for detecting a methylated genomic locus is provided.
Graham P. Lidgard, Michael J. Domanico, Hatim Allawi, Hongzhi Zou
Filed: 8 Feb 21