25 patents
Utility
System and Methods for Immune Cells Expansion and Activation In Large Scale
23 Nov 23
This invention discloses a three-dimensional (3D) bioreactor for large scale expansion of immune cells and methods of use.
Lior RAVIV, Shirley BACHAR, Dorina ROBERMAN
Filed: 23 May 23
Utility
System for 3D Cultivation of Plant Cells and Methods of Use
9 Nov 23
This invention is directed to a method for three-dimensional cultivation of proliferating plant cells in a packed bed bioreactor, the bioreactor comprising at least one packed bed chamber configured to confine said proliferating plant cells within it such that the proliferating plant cells become a three-dimensional stationary biomass phase; and At least one container comprising a fluid media, the fluid media is configured to flow through said proliferating plant cells stationary biomass phase, wherein, the flow of the fluid media through the proliferating plant cells stationary biomass phase allows transfer of compounds from the fluid media into the cells and vice versa in low sheer forces within the at least one packed bed chamber thereby imitating natural growth environment of the proliferating plant cells within the 3D bioreactor.
Lior RAVIV, Eran BEN ELIEZER
Filed: 8 Jun 23
Utility
Methods And Compositions For Aesthetic And Cosmetic Treatment And Stimulating Hair Growth
30 Jun 22
Disclosed herein are methods and compositions comprising placental adherent stromal cells, conditioned media derived from a cultured placental ASC, lysates thereof, and fractions thereof, for treating a skin condition (e.g. a compromised skin barrier, acne, wrinkles, hyper/hypo-pigmentation, dryness, elastosis); increasing skin volume, and preventing or treating alopecia and related conditions.
Yaacob YANAY, Lior RAVIV, Murielle AGASSI, Sagi MORAN
Filed: 14 Mar 22
Utility
Use of Adherent Stromal Cells for Enhancing Hematopoiesis In a Subject In Need Thereof
16 Jun 22
Disclosed herein are methods and compositions comprising adherent stromal cells.
Zami ABERMAN
Filed: 7 Mar 22
Utility
Methods and Compositions for Producing Cannabinoids
17 Feb 22
Disclosed herein are methods of producing one or more cannabinoid compounds, expanding cells that produce the compounds, cannabinoid compounds produced by the methods, pharmaceutical compositions comprising the cannabinoid compounds, and methods of producing and utilizing the compounds and compositions.
Yaacob YANAY, Lior RAVIV
Filed: 20 Apr 20
Utility
Modular Bioreactor
3 Feb 22
The present disclosure relates to use of systems for culturing, incubating, and/or expanding adherent cells.
Lior RAVIV, Nadav ESHKOL, Dorina ROBERMAN
Filed: 3 Oct 19
Utility
Methods and Compositions for Treating Subjects Exposed to Vesicants and Other Chemical Agents
18 Nov 21
Disclosed herein are methods and compositions comprising adherent stromal cells.
Arie EISENKRAFT, Yaacob YANAY, Rachel OFIR
Filed: 18 Jun 19
Utility
Therapeutic Methods and Compositions
4 Nov 21
Disclosed herein are pharmaceutical compositions and methods comprising or utilizing placental adherent stromal cells.
Zami ABERMAN, Yaacob YANAY, Rachel OFIR, Marc TRITEL, Hoshea Yissachar ALLEN, Niva SHRAGA HELED
Filed: 6 Nov 19
Utility
Methods and Compositions for Treating Viral Infections
16 Sep 21
Disclosed herein are methods and compositions comprising placental adherent stromal cells for treating viral infections and sequelae thereof.
Yaacob Yanay, Rachel Ofir, Marc Tritel
Filed: 11 Mar 21
Utility
Therapeutic Dosage Regimens Comprising Adherent Stromal Cells
29 Jul 21
Disclosed herein are pharmaceutical compositions and therapeutic dosage regimens comprising or utilizing adherent stromal cells.
Zami ABERMAN, Yaacob YANAY, Rachel OFIR, Marc TRITEL
Filed: 10 Jun 19
Utility
Methods and Compositions for Treating Cancers and Neoplasms
8 Jul 21
Described herein are methods of anti-tumor therapy using adherent stromal cells and conditioned medium produced thereby.
Zami Aberman, Rachel Ofir, Hoshea Yissachar Allen, Ariel Gilert, Niva Shraga Heled
Filed: 16 Feb 17
Utility
Methods and Compositions for Formulating and Dispensing Pharmaceutical Formulations
13 May 21
The present disclosure relates to use of specialized vessels for formulating and dispensing pharmaceutical formulations.
Lior RAVIV, Nadav ESHKOL, Dorina ROBERMAN
Filed: 16 Apr 19
Utility
Adherent Stromal Cells Derived from Placentas of Multiple Donors and Uses Thereof
22 Apr 21
Pharmaceutical compositions comprising adherent stromal cells (ASCs) are provided.
Zami Aberman, Ora Burger, Shai Meretzki
Filed: 11 Dec 20
Utility
Methods for Expanding Adherent Stromal Cells and Cells Obtained Thereby
22 Apr 21
Disclosed herein are methods of expanding adherent stromal cells, including, inter alia, multi-step methods.
Lior RAVIV, David WILDAWER, Eva Bjerge ZINO
Filed: 28 Mar 19
Utility
Methods and systems for harvesting cells
30 Nov 20
Methods for using vibration to harvest cells grown in 3D culture are provided.
Harel Kasuto, Nirit Drori-carmi, Barak Zohar
Filed: 14 May 17
Utility
Altered adherent stromal cells and methods of producing and using same
30 Nov 20
Disclosed herein are altered adherent stromal cells and methods of producing and utilizing same.
Eytan Abraham, Lior Raviv, Maya Wadamany, Nadav Eshkol
Filed: 5 Jun 16
Utility
Methods and Compositions for Aesthetic and Cosmetic Treatment and Stimulating Hair Growth
25 Nov 20
Disclosed herein are methods and compositions comprising placental adherent stromal cells, conditioned media derived from a cultured placental ASC, lysates thereof, and fractions thereof, for treating a skin condition (e.g. a compromised skin barrier, acne, wrinkles, hyper/hypo-pigmentation, dryness, elastosis); increasing skin volume, and preventing or treating alopecia and related conditions.
Yaacob Yanay, Lior Raviv, Murielle Agassi, Sagi Moran
Filed: 10 Aug 20
Utility
Adherent Cells from Placenta and Use of Same In Disease Treatment
30 Sep 20
Methods for treating conditions by administration of placenta derived adherent stromal cells to a subject in thereof are provided.
ABERMAN Zami
Filed: 21 Jan 20
Utility
Methods for Treating Radiation or Chemical Injury
30 Sep 20
Methods for treating radiation or chemical injury are described that comprise administering to a subject a therapeutically effective amount of adherent stromal cells.
Raphael GORODETSKY, Zami ABERMAN
Filed: 8 Jun 20
Utility
Methods and Compositions for Treating Neurological Disorders
5 Aug 20
Disclosed herein are methods and compositions for cell induction and treating neurological disorders, utilizing adherent stromal cells, which may, for example, be derived from placental tissue, bone marrow, or adipose tissue.
Rachel OFIR, Niva SHRAGA HELED
Filed: 22 Apr 18