6 patents
Utility
Method of treating ocular conditions by administering an antibody that activates Tie2 and binds VEGF
16 Jan 24
The disclosure provides compositions comprising multi-specific compounds, including a compound that targets a phosphatase and a receptor tyrosine kinase agonist.
Kevin Peters
Filed: 10 Dec 20
Utility
Antibodies that bind human protein tyrosine phosphatase beta (HPTPbeta) and uses thereof
14 Nov 23
Antibodies and antigen binding fragments thereof that bind to human protein tyrosine phosphatase beta (HPTPβ), and uses thereof.
Rocco Jamie Rotello, Kevin Gene Peters, Michael Glenn Davis
Filed: 7 Feb 20
Utility
Small molecule activators of Tie-2
28 Mar 23
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta.
John M. Janusz
Filed: 28 Oct 20
Utility
Formulations of Tie-2 activators and methods of use thereof
16 Aug 22
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTPβ.
Kevin Peters
Filed: 23 Jun 20
Utility
Tie-2 activators targeting the Schlemm's canal
22 Feb 22
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta.
Kevin Peters
Filed: 28 Apr 20
Utility
Humanized monoclonal antibodies that target VE-PTP (HPTP-beta)
23 Nov 21
The disclosure provides compositions and methods for the treatment of ocular conditions associated with angiogenesis comprising administering an antibody that targets a tyrosine phosphatase inhibitor in a subject.
Kevin Peters, Michael Allen Flynn
Filed: 17 Apr 20
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