25 patents
Utility
Canine antibody libraries
18 Jul 23
The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries.
Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
Filed: 22 Apr 21
Utility
Clinical assessment of M-protein response in multiple myeloma
4 Apr 23
Applicant discloses an anti-idiotypic antibody to MOR202, which when fused to human albumin, shifted the anti-body in IFE thus mitigating any potential interference of MOR202 with the M-protein clinical assessment.
Stefan Härtle
Filed: 3 Mar 17
Utility
Treatment for multiple myeloma (MM)
28 Feb 23
The present disclosure relates to the treatment of multiple myeloma.
Stéphane LeClair, Jan Endell, Stefan Härtle
Filed: 25 Nov 19
Utility
Antibodies targeting Glycoprotein VI
3 Jan 23
The present disclosure provides antibodies or antibody fragments specific for GPVI.
Kerstin Uhland, Julia Neugebauer, Steffen Runz
Filed: 15 May 19
Utility
Humanized antibodies for CD3
18 Oct 22
The present disclosure provides humanized antibodies that specifically bind to CD3 with an optimized affinity and induce T cell-mediated killing of tumour related target antigen high expressing cells with high potency but have limited killing activity on target antigen low expressing cells.
Thomas Tiller, Steffen Runz, Julia Neugebauer, Andreas Bültmann
Filed: 13 Aug 18
Utility
Anti-CD19 antibody formulations
7 Jun 22
The present disclosure describes a pharmaceutical formulation of an anti-CD19 antibody.
Patrick Garidel, Andreas Langer, Martin Hessling, Daniel Weinfurtner, Bodo Brocks
Filed: 27 Jun 17
Utility
Peptide libraries
7 Jun 22
The invention relates to novel libraries of linear and cyclic peptides, and methods of generating and screening such libraries for biological, pharmaceutical and other uses.
Katja Siegers, Jan Van Den Brulle
Filed: 8 Sep 20
Utility
Fab molecules with a rodent hinge region and a non-rodent CH1 region
22 Feb 22
The disclosure relates to novel Fab molecules comprising a modified heavy chain constant region.
Julia Neugebauer, Steffen Runz, Stefanie Urlinger
Filed: 13 Nov 17
Utility
Combinations and uses thereof
18 Jan 22
The present disclosure describes a pharmaceutical combination of an anti-CD19 antibody and a phosphoinositide 3-kinase inhibitor for the treatment of non-Hodgkin's lymphoma, chronic lymphocytic leukemia and/or acute lymphoblastic leukemia.
Jan Endell, Mark Winderlich, Rainer Boxhammer
Filed: 18 Aug 16
Utility
Polypeptide library
10 Aug 21
The invention relates to novel polypeptide libraries that are conformationally constrained in an anti-parallel, helix-turn-helix arrangement.
Roger Müller, Andreas Bültmann, Josef Prassler, Markus Moosmeier
Filed: 8 Apr 20
Utility
Generation and profiling of fully human HuCAL GOLD-derived therapeutic antibodies specific for human CD38
13 Jul 21
The present invention provides novel antibodies and methods for using recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions.
Michael Tesar, Ute Jäger
Filed: 7 Sep 18
Utility
Nucleic acid encoding anti-GM-CSF antibodies
8 Jun 21
The present invention provides recombinant antigen-binding regions, antibodies and functional fragments thereof that are specific for GM-CSF, which plays an integral role in various disorders or conditions.
Stefan Steidl, Elisabeth Thomassen-Wolf
Filed: 17 Jun 19
Utility
Canine antibody libraries
25 May 21
The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries.
Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
Filed: 21 Jun 18
Utility
Rodent combinatorial antibody libraries
16 Feb 21
The present invention provides synthetic rodent antibody libraries, such as mouse or rat antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries.
Josef Prassler, David Ott, Stefanie Thiel, Yvonne Stark, Ute Keck, Thomas Pietzonka, Hilmar Ebersbach
Filed: 10 Mar 17
Utility
Treatment for rheumatoid arthritis
9 Feb 21
The present invention provides anti-GM-CSF antibodies for use in the treatment of rheumatoid arthritis.
Stefan Hartle, Stephane Leclair, Amgad Shebl, Stefan Steidl, Bodo Brocks, Daniela Della Ducata, Kai Rosport
Filed: 26 Jan 18
Utility
Anti-WT1/HLA-specific antibodies
16 Nov 20
The present invention relates to antibodies or fragments thereof binding to human WT1/HLA.
Andrea Mahr, Toni Weinschenk, Dominik Maurer, Claudia Wagner, Klaus Felix Hartlepp, Alexandra Kraus
Filed: 6 Oct 16
Utility
Peptide libraries
2 Nov 20
The invention relates to novel libraries of linear and cyclic peptides, and methods of generating and screening such libraries for biological, pharmaceutical and other uses.
Katja Siegers, Jan Van Den Brulle
Filed: 29 Apr 15
Utility
Antagonists of IL17C for the treatment of inflammatory disorders
26 Oct 20
The present invention provides antagonists of IL17C for use in the treatment of an inflammatory disorder.
Andreas Bültmann, Robert Mühlbacher, Teresa Garcia, Reginald Christophe Xavier Brys, Luc Nelles, Katja Conrath
Filed: 7 Nov 18
Utility
Complex-specific antibodies and antibody fragments and its use
14 Sep 20
The present invention provides antibodies and fragments thereof that specifically detect the complex of a specific cognate antigen-binding moiety, in particular antibodies, and its antigen.
Stefan Haertle, Christian Frisch, Achim Knappik
Filed: 18 Dec 17
Utility
Polypeptide library
18 May 20
The invention relates to novel polypeptide libraries that are conformationally constrained in an anti-parallel, helix-turn-helix arrangement.
Roger Müller, Andreas Bültmann, Josef Prassler, Markus Moosmeier
Filed: 2 Mar 17